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Heart Disorder

Nitrocin 5ML Injection Marketer Samarth Life Sciences Pvt Ltd SALT COMPOSITION Nitroglycerin (5mg/ml) Salt Synonyms Glyceryl Trinitrate Storage Store below 30°C Uses of Nitrocin Injection Angina (heart-related chest pain) Heart Failure Treatment of Hypertension (high blood pressure) Coronary artery disease Hypertensive emergency Anal fissure Product introduction Nitrocin 5mg Injection is used to treat and prevent heart-related chest pain (angina) and hypertension (high blood pressure) during surgery. This medicine works by relaxing and widening blood vessels so blood can flow more easily to the heart. It has a very short-lived effect. Nitrocin 5mg Injection is given as an injection under the supervision of a doctor with careful blood pressure monitoring. This is given as a continuous infusion into a vein and should not be stopped abruptly. It should not be mixed with any other medication of any kind. The most common side effect of Nitrocin 5mg Injection is a headache which may be severe. This can sometimes be helped by drinking plenty of fluids and avoiding alcohol. You may also experience lightheadedness, which could increase your risk of having a fall. There are other, rarer side effects, some of them serious. Ask your doctor and read the leaflet which comes with the medicine to make sure you are keeping safe. Do not use Nitrocin 5mg Injection if you are taking medicines to treat high blood pressure in your lungs (pulmonary hypertension), or erectile dysfunction; or if you have anemia or glaucoma (increased pressure inside the eye). Always tell your doctor what other health conditions you have and what other medicines you are taking. It is best not to drink alcohol with this medicine as it increases some of the side effects. If you are affected by dizziness, avoid driving. If you are pregnant, thinking about becoming pregnant, or breastfeeding, ask your doctor before taking this medicine. Benefits of Nitrocin Injection In Treatment of Hypertension (high blood pressure) Nitrocin 5mg Injection is used to treat hypertension in hypertensive emergencies. It rapidly dilates (widens) the blood vessels. This rapid vasodilation helps reduce blood pressure levels, relieving the strain on the heart and improving blood flow to vital organs. It is typically used in critical situations where immediate blood pressure reduction is necessary, such as severe high blood pressure that can lead to organ damage or other life-threatening complications. Side effects of Nitrocin Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Nitrocin Blurred vision Decreased blood pressure Dizziness Headache Increased heart rate Lightheadedness Paresthesia (tingling or pricking sensation) How to use Nitrocin Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Nitrocin Injection works Nitrocin 5mg Injection is a nitrate. It works by improving blood supply to heart and relaxing the blood vessels which decreases the oxygen demand of the heart and reduces its workload, thereby preventing/treating attacks of angina (chest pain). Relaxation of blood vessels lowers blood pressure. Safety advice warnings Alcohol UNSAFE Consuming alcohol while taking Nitrocin 5mg Injection may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction). warnings Pregnancy SAFE IF PRESCRIBED Nitrocin 5mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies. warnings Breast feeding SAFE IF PRESCRIBED Nitrocin 5mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. warnings Driving UNSAFE Nitrocin 5mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. warnings Kidney SAFE IF PRESCRIBED Nitrocin 5mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nitrocin 5mg Injection may not be needed in these patients. Please consult your doctor. warnings Liver CONSULT YOUR DOCTOR There is limited information available on the use of Nitrocin 5mg Injection in patients with liver disease. Please consult your doctor.

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Heart Disorder

Prostal 500mcg Injection Salt Composition : Alprostadil Manufacturer : CELON LABORATORIES LTD Introduction to Prostal 500mcg Injection Prostal 500mcg injection contains active components called Alprostadil. This medication is often used to treat ED in men with difficulty achieving or maintaining an erection. It may be used to improve blood flow in patients with peripheral arterial disease (PAD), a condition in which blood flow to the extremities (usually the legs) is reduced. In newborns with certain heart conditions, such as PDA, it can open a blood vessel called the ductus arteriosus. It can also be used in diagnostic tests to assess blood flow in specific body areas, such as during penile Doppler ultrasound studies to evaluate erectile function. Individuals who have a known allergy or hypersensitivity to Alprostadil or any of its components should not use the medication. It should be avoided in men with penile implants or conditions that make penile injections unsafe, such as penile fibrosis, curvature, or priapism (prolonged erections). It should not be used in individuals with conditions predisposing them to priapism, such as sickle cell anemia, multiple myeloma, or leukemia. It should not be used in individuals who experience unexplained genital or pelvic pain, as it may indicate an underlying medical condition. Individuals with bleeding disorders or those taking anticoagulant medications (blood thinners) should use Prostal 500mcg injection cautiously, as it may increase the risk of bleeding at the injection site. It should not be used concomitantly with alpha-blocker medications used to treat conditions like benign prostatic hyperplasia (BPH) and high blood pressure, as it can lead to severe low blood pressure. It should not be used in infants with congenital heart defects who have conditions that are worsened by increased blood flow to the lungs. It can be used in elderly patients, but caution may be required. Uses of Prostal 500mcg Injection Erectile dysfunction (ED) Peripheral arterial disease (PAD) Patent ductus arteriosus (PDA) in Infants Diagnostic testing Therapeutic Effects of Prostal 500mcg Injection Prostal 500mcg injection binds to specific receptors on smooth muscle cells in blood vessels and various tissues. When it binds to these receptors, it triggers biochemical events that lead to vasodilation. It relaxes the smooth muscles in blood vessel walls, particularly in the penis, when used for erectile dysfunction. It involves promoting the relaxation of smooth muscle cells, improving blood flow to specific body areas, depending on its intended use. Interaction of Prostal 500mcg Injection with other drugs Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Prostal 500mcg injection, reducing effectiveness by causing undesirable side effects. More Information about Prostal 500mcg Injection Store at room temperature below 20 to 25°C Keep away from moisture, heat, and light. It should not be frozen. Keep away from children and pets. How to consume Prostal 500mcg Injection Prostal 500mcg injection can be administered via various routes, depending on the medical condition. For erectile dysfunction (ED), it can be injected directly into the penis (intracavernosal injection), applied topically to the penile tip (urethral application), or used as a urethral suppository. Safety Advices for Prostal 500mcg Injection Image Not Available Pregnancy If you are pregnant or trying to become pregnant, it is important to talk to your doctor before taking Prostal 500mcg injection. Image Not Available Breast Feeding There is limited research on the safety of Prostal 500mcg injection in breastfeeding women. It is important to talk to your doctor before taking this medication. Image Not Available Lungs If you have lung diseases, talking to your doctor before taking Prostal 500mcg injection is important. Image Not Available Liver Prostal 500mcg injection is metabolized in the liver, so individuals with severe liver disease may require dose adjustments. Patients with liver problems should discuss their condition with their healthcare provider before using it. Image Not Available Alcohol It is unsafe to drink alcohol while taking Prostal 500mcg injection. Excessive alcohol consumption can increase the risk of certain side effects. Image Not Available Driving Prostal 500mcg injection can cause dizziness or fainting, especially if low blood pressure occurs. If you experience any side effects, consult your healthcare provider before taking it while driving. Side Effects of Prostal 500mcg Injection Prostal 500mcg injection causes some side effects like all medications, although not everyone will experience them. Serious: Priapism Penile fibrosis Allergic reactions Low blood pressure Cardiovascular effects Bleeding Common:

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Anti Cancer Medicine

Decarb 200mg injection is an antineoplastic drug belonging to the class of alkylating agents, containing the active ingredient Dacarbazine. It is used to prevent and treat metastatic malignant melanoma (skin cancer), Hodgkin's disease (cancer that forms in the lymph system, part of the immune system). It is often combined with cisplatin, a cytotoxic agent, to treat certain types of cancers for the treatment of Hodgkin's lymphoma, and also combined with temozolomide for the treatment of melanoma. There may be an increased risk of certain types of skin cancer (non-melanoma skin cancer) with the use of this medicine. This drug is contraindicated in pregnant women, and women of childbearing potential should use effective contraception during and for at least 6 months after treatment with the drug. It is not known whether it is excreted in human milk, so breastfeeding should be avoided during treatment with the drug. It should also be used with caution in patients with pre-existing liver or kidney dysfunction. You should not have a live vaccine if you are having this injection. This is because it may weaken your immune system and make you more likely to catch a serious infection. Consult your doctor immediately for more advice.

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Anti Cancer Medicine

Decarb 500mg injection is an antineoplastic drug belonging to the class of alkylating agents, containing the active ingredient Dacarbazine. It is used to prevent and treat metastatic malignant melanoma (skin cancer), Hodgkin's disease (cancer that forms in the lymph system, part of the immune system). It is often combined with cisplatin, a cytotoxic agent, to treat certain types of cancers for the treatment of Hodgkin's lymphoma, and also combined with temozolomide for the treatment of melanoma. There may be an increased risk of certain types of skin cancer (non-melanoma skin cancer) with the use of this medicine. This drug is contraindicated in pregnant women, and women of childbearing potential should use effective contraception during and for at least 6 months after treatment with the drug. It is not known whether it is excreted in human milk, so breastfeeding should be avoided during treatment with the drug. It should also be used with caution in patients with pre-existing liver or kidney dysfunction. You should not have a live vaccine if you are having this injection. This is because it may weaken your immune system and make you more likely to catch a serious infection. Consult your doctor immediately for more advice.

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Anti Cancer Medicine

Introduction to Dacsted 200mg Injection Dacsted 200mg injection is an antineoplastic drug belonging to the class of alkylating agents, containing the active ingredient dacarbazine. It is used to prevent and treat metastatic malignant melanoma (skin cancer), Hodgkin's disease (cancer that forms in the lymph system, part of the immune system). It is often combined with cisplatin, an cytotoxic agent, to treat certain types of cancers for the treatment of Hodgkin's lymphoma, and dacarbazine with temozolomide for the treatment of melanoma. There may be an increased risk of certain types of skin cancer (non-melanoma skin cancer) with the use of this medicine. This drug is contraindicated in pregnant women, and women of childbearing potential should use effective contraception during and for at least 6 months after treatment with the drug. It is not known whether dacsted 200mg injection is excreted in human milk, so breastfeeding should be avoided during treatment with the drug. It should also be used with caution in patients with pre-existing liver or kidney dysfunction. You should not have a live vaccine if you are having dacsted 200mg injection. This is because dacsted 200mg injection may weaken your immune system and make you more likely to catch a serious infection. Consult your doctor immediately for more advice. Dacsted 200mg injection may cause pain along the vein. If you feel pain, tell your nurse straight away so that the infusion site can be checked. They may give the drug more slowly or flush it through with more fluids to reduce pain. Treatment should not be started if your white blood cells (leukocytes) have fallen to counts below determined levels. Your doctor will determine these values at regular intervals. This medicine should not be used if you are allergic to dacarbazine. Before each administration you will have blood tests to check that you have enough blood cells to receive this medicine. It is usually administered once every three to four weeks. Tell your physician about all the medications you have been taking recently, including herbal medicines and supplements, before taking dacsted 200mg injection. Uses of Dacsted 200mg Injection Metastatic malignant melanoma Hodgkin’s disease Therapeutic Effects of Dacsted 200mg Injection It is a type of alkylating agent, which works majorly through the process of alkylation. It enters the cancer cells after getting activated by the liver and inhibits DNA synthesis. This process disrupts the normal cell cycle and DNA function, leading to arrest in cancer cell growth and multiplication. Interaction of Dacsted 200mg Injection with other drugs Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Dacsted 200mg injection and reduce effectiveness by causing undesirable side effects. More Information about Dacsted 200mg Injection Store Dacsted 200mg injection in the refrigerator (2°-8°C). Do not freeze. Keep it out of reach from children and pets. How to consume Dacsted 200mg Injection The medicine will be administered to you by a healthcare professional in a hospital setting. This injection will be given intravenously into a vein in your arm or hand. Do not self-administer this medicine. The specific dose and schedule of administration depend on the type and stage of cancer being treated. Dacsted 200mg injection Injection is usually given about 30 minutes before you receive your anti-cancer medicine (chemotherapy). During the infusion, you will be monitored for any side effects or reactions to the medication. It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor and reschedule the dose. Safety Advices for Dacsted 200mg Injection Image Not Available Pregnancy Dacsted 200mg injection is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment. Image Not Available Breast Feeding It is not known if dacsted 200mg injection Injection passes into your breast milk or if it will affect your baby. Please consult your doctor before breastfeeding. Image Not Available Lungs No Data Image Not Available Liver Inform your doctor if you have any liver problems before taking dacsted 200mg injection. Regular monitoring of liver function tests is recommended. Image Not Available Alcohol Consuming alcohol may affect the effectiveness of dacsted 200mg injection. Stop consuming alcohol if you are taking this medicine. Image Not Available Driving It is unsafe to drive vehicles or operate heavy machinery after taking dacsted 200mg injection Injection, it may cause dizziness and impair your concentration.

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General Medicine

Dobutacan 12 Injection is a brand of Dobutamine Hydrochloride 12.5 mg/mL, a synthetic catecholamine used in critical care settings to support heart function. It is administered intravenously under medical supervision. ________________________________________ 🩺 Medical Uses Dobutacan 12 Injection is indicated for: • Cardiac Decompensation: Acute heart failure due to conditions like myocardial infarction, cardiomyopathies, or post-cardiac surgery. • Cardiogenic Shock: A state of low cardiac output leading to inadequate tissue perfusion. • Septic Shock: A severe infection causing low blood pressure and organ dysfunction. • Stress Echocardiography: As a pharmacological agent to assess coronary artery disease when exercise is not feasible. It works by stimulating beta-1 adrenergic receptors, increasing heart contractility and stroke volume, thereby improving cardiac output. ________________________________________ ⚙️ Dosage and Administration Dobutacan 12 Injection is administered intravenously in a hospital setting. The typical dosage ranges from 2.5 to 10 mcg/kg/min, adjusted based on the patient's response. In some cases, doses up to 20 mcg/kg/min may be required. ________________________________________ ⚠️ Precautions and Contraindications Before using Dobutacan 12 Injection, inform your healthcare provider if you have: • Allergies to dobutamine or other components of the injection. • A history of arrhythmias or heart disease. • Kidney or liver problems. • A history of stroke or blood clots. This medication is typically administered by healthcare professionals in a clinical setting and is not intended for self-administration. It is usually given as an intramuscular (IM) or intravenous (IV) injection. ________________________________________ 💊 Side Effects Common side effects may include: • Headache • Nausea or vomiting • Dizziness or lightheadedness • Injection site reactions (pain, redness, or swelling) Serious side effects are rare but can occur. Seek immediate medical attention if you experience symptoms like chest pain, shortness of breath, or signs of gastrointestinal bleeding.

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General Medicine

Ceforzone SB 1.5 Injection is a combination antibiotic formulation containing Cefoperazone (1000 mg) and Sulbactam (500 mg). Manufactured by American Remedies, it is primarily used to treat a wide range of bacterial infections. ________________________________________ 🩺 Uses of Ceforzone SB 1.5 Injection Ceforzone SB 1.5 Injection is indicated for the treatment of various bacterial infections, including: • Respiratory Tract Infections: Such as pneumonia and bronchitis. • Urinary Tract Infections: Including cystitis and pyelonephritis. • Intra-abdominal Infections: Such as peritonitis and abscesses. • Skin and Soft Tissue Infections: Including cellulitis and wound infections. • Bone and Joint Infections: Such as osteomyelitis and septic arthritis. • Meningitis: Infection of the membranes covering the brain and spinal cord. • Pelvic Inflammatory Disease: Infection of the female reproductive organs. • Gonorrhea: A sexually transmitted infection. Septicemia: Bloodstream infection. Surgical Prophylaxis: To prevent infections associated with major surgeries. ________________________________________ 💊 Mechanism of Action • Cefoperazone: A third-generation cephalosporin antibiotic that inhibits the synthesis of the bacterial cell wall, leading to cell lysis and death. Sulbactam: A beta-lactamase inhibitor that protects cefoperazone from enzymatic degradation by bacterial beta-lactamases, thereby enhancing its antibacterial activity. ________________________________________ ⚠️ Precautions • Allergy: Inform your healthcare provider if you have a history of allergic reactions to penicillins, cephalosporins, or beta-lactam antibiotics. • Liver or Kidney Impairment: Use with caution in patients with liver or kidney dysfunction. Dosage adjustments may be necessary. • Pregnancy and Breastfeeding: Consult your doctor before use during pregnancy or breastfeeding. • Drug Interactions: Inform your healthcare provider about all other medications you are taking to avoid potential interactions.

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General Medicine

Bluecan Injection is a brand of Methylene Blue Injection, primarily used in medical settings for its diagnostic and therapeutic properties. ________________________________________ 🩺 Uses of Bluecan Injection 1. Treatment of Methemoglobinemia: Methylene Blue is the first-line treatment for methemoglobinemia, a condition where methemoglobin levels are elevated, impairing oxygen delivery to tissues. It acts as a reducing agent, converting methemoglobin back to hemoglobin, thereby restoring normal oxygen transport. 2. Urinary Tract Infections (UTIs): It is sometimes used as a urinary antiseptic to treat UTIs, although its use for this purpose has become less common with the advent of more effective antibiotics. 3. Surgical Dye: In surgical procedures, Methylene Blue is used as a dye to delineate tissues, identify sentinel lymph nodes, or assess organ perfusion. 4. Diagnostic Tool: It is used in diagnostic procedures to assess the function of certain organs, such as the kidneys, and to evaluate the patency of ducts. ________________________________________ ⚠️ Side Effects While generally well-tolerated, potential side effects of Methylene Blue Injection include: • Injection site reactions (pain, redness, swelling) • Headache • Dizziness • Nausea or vomiting • Skin discoloration (temporary blue or greenish tint) • In rare cases, serotonin syndrome, especially if used with serotonergic drugs ________________________________________ 💊 Mechanism of Action Methylene Blue acts by accepting electrons and donating them to reduce methemoglobin back to hemoglobin. This process restores the oxygen-carrying capacity of the blood. It also inhibits certain enzymes and has antimicrobial properties, which contribute to its use in treating infections. ________________________________________ ⚠️ Precautions • Drug Interactions: Avoid concurrent use with serotonergic drugs (e.g., SSRIs, SNRIs, MAO inhibitors) to prevent serotonin syndrome. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. • G6PD Deficiency: Use with caution in individuals with glucose-6-phosphate dehydrogenase deficiency, as it may cause hemolysis. • Renal Impairment: Dosage adjustments may be necessary in patients with kidney dysfunction

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