Nitrocin 5ML Injection Marketer Samarth Life Sciences Pvt Ltd SALT COMPOSITION Nitroglycerin (5mg/ml) Salt Synonyms Glyceryl Trinitrate Storage Store below 30°C Uses of Nitrocin Injection Angina (heart-related chest pain) Heart Failure Treatment of Hypertension (high blood pressure) Coronary artery disease Hypertensive emergency Anal fissure Product introduction Nitrocin 5mg Injection is used to treat and prevent heart-related chest pain (angina) and hypertension (high blood pressure) during surgery. This medicine works by relaxing and widening blood vessels so blood can flow more easily to the heart. It has a very short-lived effect. Nitrocin 5mg Injection is given as an injection under the supervision of a doctor with careful blood pressure monitoring. This is given as a continuous infusion into a vein and should not be stopped abruptly. It should not be mixed with any other medication of any kind. The most common side effect of Nitrocin 5mg Injection is a headache which may be severe. This can sometimes be helped by drinking plenty of fluids and avoiding alcohol. You may also experience lightheadedness, which could increase your risk of having a fall. There are other, rarer side effects, some of them serious. Ask your doctor and read the leaflet which comes with the medicine to make sure you are keeping safe. Do not use Nitrocin 5mg Injection if you are taking medicines to treat high blood pressure in your lungs (pulmonary hypertension), or erectile dysfunction; or if you have anemia or glaucoma (increased pressure inside the eye). Always tell your doctor what other health conditions you have and what other medicines you are taking. It is best not to drink alcohol with this medicine as it increases some of the side effects. If you are affected by dizziness, avoid driving. If you are pregnant, thinking about becoming pregnant, or breastfeeding, ask your doctor before taking this medicine. Benefits of Nitrocin Injection In Treatment of Hypertension (high blood pressure) Nitrocin 5mg Injection is used to treat hypertension in hypertensive emergencies. It rapidly dilates (widens) the blood vessels. This rapid vasodilation helps reduce blood pressure levels, relieving the strain on the heart and improving blood flow to vital organs. It is typically used in critical situations where immediate blood pressure reduction is necessary, such as severe high blood pressure that can lead to organ damage or other life-threatening complications. Side effects of Nitrocin Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Nitrocin Blurred vision Decreased blood pressure Dizziness Headache Increased heart rate Lightheadedness Paresthesia (tingling or pricking sensation) How to use Nitrocin Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Nitrocin Injection works Nitrocin 5mg Injection is a nitrate. It works by improving blood supply to heart and relaxing the blood vessels which decreases the oxygen demand of the heart and reduces its workload, thereby preventing/treating attacks of angina (chest pain). Relaxation of blood vessels lowers blood pressure. Safety advice warnings Alcohol UNSAFE Consuming alcohol while taking Nitrocin 5mg Injection may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction). warnings Pregnancy SAFE IF PRESCRIBED Nitrocin 5mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies. warnings Breast feeding SAFE IF PRESCRIBED Nitrocin 5mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. warnings Driving UNSAFE Nitrocin 5mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. warnings Kidney SAFE IF PRESCRIBED Nitrocin 5mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nitrocin 5mg Injection may not be needed in these patients. Please consult your doctor. warnings Liver CONSULT YOUR DOCTOR There is limited information available on the use of Nitrocin 5mg Injection in patients with liver disease. Please consult your doctor.

Icikinase 1.5MIU Injection Marketer Abbott SALT COMPOSITION Streptokinase (1500000IU) Storage Store in a refrigerator (2 - 8°C). Do not freeze. Uses of Icikinase Injection Heart attack Pulmonary embolism Product introduction Icikinase 1.5MIU Injection is a medicine used to break down harmful blood clots that have formed in the blood vessels. It is used to treat patients who have suffered a recent heart attack. It is also used in treating conditions such as pulmonary embolism and stroke. Icikinase 1.5MIU Injection is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. The doctor may closely monitor your condition until you become stable. Use of this medicine may cause injection site bleeding, nausea, allergic reaction, and a decrease in blood pressure. It may increase your risk of bleeding also. Your doctor will explain the benefits and risks associated with this medicine before it is administered. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection. This medicine is used with caution for some people. Thus, you must inform the doctor if you are suffering from any bleeding disorder, kidney, or liver disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly. Side effects of Icikinase Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Icikinase Allergic reaction Nausea Injection site bleeding Decrease in blood pressure How to use Icikinase Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Icikinase Injection works Icikinase 1.5MIU Injection works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected tissue, thereby preventing tissue death and improving outcomes. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Icikinase 1.5MIU Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Icikinase 1.5MIU Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. warnings Breast feeding CONSULT YOUR DOCTOR Information regarding the use of Icikinase 1.5MIU Injection during breastfeeding is not available. Please consult your doctor. warnings Driving NOT RELEVANT Not relevant, as Icikinase 1.5MIU Injection is intended for use in hospitalised patients. warnings Kidney SAFE IF PRESCRIBED Icikinase 1.5MIU Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Icikinase 1.5MIU Injection may not be needed in these patients. Please consult your doctor. Use of Icikinase 1.5MIU Injection is not recommended in patients with severe kidney disease. warnings Liver CAUTION Icikinase 1.5MIU Injection should be used with caution in patients with severe liver disease. Dose adjustment of Icikinase 1.5MIU Injection may be needed. Please consult your doctor. What if you forget to take Icikinase Injection? If you miss a dose of Icikinase 1.5MIU Injection, please consult your doctor.n

Brilinta 90mg Tablet Marketer AstraZeneca SALT COMPOSITION Ticagrelor (90mg) Storage Store below 30°C Uses of Brilinta Tablet Heart attack Prevention of heart attack and stroke Unstable angina Product introduction Brilinta 90mg Tablet belongs to a group of medicines called antiplatelet or blood thinners. It reduces the formation of harmful blood clots in blood vessels, which helps to prevent heart attacks or strokes in people with heart disease. Brilinta 90mg Tablet is also used to treat people with a recent heart attack or severe heart-related chest pain (unstable angina) who have undergone stenting of the heart. It helps to prevent serious heart-related problems like having another heart attack, stroke, or formation of blood clots in stents in such people. Your doctor will also prescribe aspirin, another antiplatelet medicine, along with this medicine. Brilinta 90mg Tablet may be taken with or without food and should be taken regularly at the same time each day. It is important to keep taking it even if you feel well. If you stop taking this medicine, it may increase your chances of having another heart attack or stroke. The most common side effects of this medicine are dyspnea (breathlessness) and bleeding. If you cut or injure yourself, it may take longer than usual for the bleeding to stop. Such episodes of bleeding are usually mild and resolve on their own. Mild breathlessness caused by this medicine usually resolves on its own with continued treatment. Let your doctor know if bleeding persists or if the breathlessness worsens or does not go away. Brilinta 90mg Tablet is not suitable for some people. Do not take it if you are bleeding from anywhere in the body, such as a stomach ulcer or bleeding within the brain. It is also not recommended for people with liver diseases. Before using the medicine, inform your doctor of any such problems. Benefits of Brilinta Tablet In Prevention of heart attack and stroke Brilinta 90mg Tablet is an antiplatelet medicine or blood thinner. It prevents blood from clotting inside the veins and arteries, helping the blood flow freely around your body and preventing a heart attack or stroke (deep vein thrombosis or pulmonary embolism). To achieve maximum benefits, take this medicine regularly and make appropriate lifestyle changes. It is often prescribed with a low dose of aspirin, which also helps prevent blood from clotting. Side effects of Brilinta Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Brilinta Bleeding Breathlessness How to use Brilinta Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Brilinta 90mg Tablet may be taken with or without food, but it is better to take it at a fixed time. How Brilinta Tablet works Brilinta 90mg Tablet is an antiplatelet medication. It works by preventing platelets from sticking together, thereby decreasing the formation of harmful blood clots. This lowers the chance of heart attack or stroke. Safety advice warnings Alcohol CAUTION Caution is advised when consuming alcohol with Brilinta 90mg Tablet. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Brilinta 90mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. warnings Breast feeding CONSULT YOUR DOCTOR Information regarding the use of Brilinta 90mg Tablet during breastfeeding is not available. Please consult your doctor. warnings Driving CONSULT YOUR DOCTOR It is not known whether Brilinta 90mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Dizziness, confusion, vertigo, and syncope have been reported in some patients. If you experience such symptoms, be cautious while driving or using machines. warnings Kidney SAFE IF PRESCRIBED Brilinta 90mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Brilinta 90mg Tablet is recommended. Limited information is available on the use of Brilinta 90mg Tablet in renal dialysis patients. warnings Liver SAFE IF PRESCRIBED Brilinta 90mg Tablet is safe to use in patients with liver disease. No dose adjustment of Brilinta 90mg Tablet is recommended. Use of Brilinta 90mg Tablet is not recommended in patients with severe liver disease.

Prostal 500mcg Injection Salt Composition : Alprostadil Manufacturer : CELON LABORATORIES LTD Introduction to Prostal 500mcg Injection Prostal 500mcg injection contains active components called Alprostadil. This medication is often used to treat ED in men with difficulty achieving or maintaining an erection. It may be used to improve blood flow in patients with peripheral arterial disease (PAD), a condition in which blood flow to the extremities (usually the legs) is reduced. In newborns with certain heart conditions, such as PDA, it can open a blood vessel called the ductus arteriosus. It can also be used in diagnostic tests to assess blood flow in specific body areas, such as during penile Doppler ultrasound studies to evaluate erectile function. Individuals who have a known allergy or hypersensitivity to Alprostadil or any of its components should not use the medication. It should be avoided in men with penile implants or conditions that make penile injections unsafe, such as penile fibrosis, curvature, or priapism (prolonged erections). It should not be used in individuals with conditions predisposing them to priapism, such as sickle cell anemia, multiple myeloma, or leukemia. It should not be used in individuals who experience unexplained genital or pelvic pain, as it may indicate an underlying medical condition. Individuals with bleeding disorders or those taking anticoagulant medications (blood thinners) should use Prostal 500mcg injection cautiously, as it may increase the risk of bleeding at the injection site. It should not be used concomitantly with alpha-blocker medications used to treat conditions like benign prostatic hyperplasia (BPH) and high blood pressure, as it can lead to severe low blood pressure. It should not be used in infants with congenital heart defects who have conditions that are worsened by increased blood flow to the lungs. It can be used in elderly patients, but caution may be required. Uses of Prostal 500mcg Injection Erectile dysfunction (ED) Peripheral arterial disease (PAD) Patent ductus arteriosus (PDA) in Infants Diagnostic testing Therapeutic Effects of Prostal 500mcg Injection Prostal 500mcg injection binds to specific receptors on smooth muscle cells in blood vessels and various tissues. When it binds to these receptors, it triggers biochemical events that lead to vasodilation. It relaxes the smooth muscles in blood vessel walls, particularly in the penis, when used for erectile dysfunction. It involves promoting the relaxation of smooth muscle cells, improving blood flow to specific body areas, depending on its intended use. Interaction of Prostal 500mcg Injection with other drugs Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Prostal 500mcg injection, reducing effectiveness by causing undesirable side effects. More Information about Prostal 500mcg Injection Store at room temperature below 20 to 25°C Keep away from moisture, heat, and light. It should not be frozen. Keep away from children and pets. How to consume Prostal 500mcg Injection Prostal 500mcg injection can be administered via various routes, depending on the medical condition. For erectile dysfunction (ED), it can be injected directly into the penis (intracavernosal injection), applied topically to the penile tip (urethral application), or used as a urethral suppository. Safety Advices for Prostal 500mcg Injection Image Not Available Pregnancy If you are pregnant or trying to become pregnant, it is important to talk to your doctor before taking Prostal 500mcg injection. Image Not Available Breast Feeding There is limited research on the safety of Prostal 500mcg injection in breastfeeding women. It is important to talk to your doctor before taking this medication. Image Not Available Lungs If you have lung diseases, talking to your doctor before taking Prostal 500mcg injection is important. Image Not Available Liver Prostal 500mcg injection is metabolized in the liver, so individuals with severe liver disease may require dose adjustments. Patients with liver problems should discuss their condition with their healthcare provider before using it. Image Not Available Alcohol It is unsafe to drink alcohol while taking Prostal 500mcg injection. Excessive alcohol consumption can increase the risk of certain side effects. Image Not Available Driving Prostal 500mcg injection can cause dizziness or fainting, especially if low blood pressure occurs. If you experience any side effects, consult your healthcare provider before taking it while driving. Side Effects of Prostal 500mcg Injection Prostal 500mcg injection causes some side effects like all medications, although not everyone will experience them. Serious: Priapism Penile fibrosis Allergic reactions Low blood pressure Cardiovascular effects Bleeding Common:

Norbit Injection Marketer Celon Laboratories Ltd SALT COMPOSITION Norepinephrine (2mg) Storage Store below 30°C Uses of Norbit Injection Low blood pressure Severe allergic reactions Glaucoma Decreased blood pressure Local anesthesia (Numb tissues in a specific area) Bleeding Allergic conditions Cardiac arrest Product introduction Norbit Injection is used to treat hypotension (low blood pressure) that may occur due to causes such as sepsis (infection). It helps to increase blood pressure by narrowing the blood vessels of the heart. It may be used to revive a patient with cardiac arrest. Norbit Injection is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. Doctor may closely monitor your blood pressure and heart rate till you became stable. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection. Your doctor may advise for regular monitoring of blood pressure. It may cause side effects like high blood pressure, headache, and insomnia (difficulty in sleeping). You must inform the doctor if you are suffering from diabetes, liver, heart or kidney disease. Also, let your doctor know about all the other medications that you are using regularly. This medicine is not usually recommended during pregnancy or breastfeeding, so always consult your doctor before taking it. Benefits of Norbit Injection In Low blood pressure Norbit Injection is used to normalise decreased blood pressure (hypotension) which may occur all of a sudden during an operation, severe infection (sepsis) or due to an emergency condition (cardiac arrest). This medicine helps to bring back the blood pressure within normal range and therefore prevents any sudden fall or even serious complications that might have otherwise followed due to low blood pressure. Side effects of Norbit Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Norbit Systemic hypertension (high blood pressure) Headache Restlessness Insomnia (difficulty in sleeping) Palpitations Tremors How to use Norbit Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Norbit Injection works NA. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Norbit Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Norbit Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. warnings Breast feeding CONSULT YOUR DOCTOR Norbit Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. warnings Driving NOT RELEVANT Not relevant, as Norbit Injection is intended for use in hospitalised patients. warnings Kidney CONSULT YOUR DOCTOR There is limited information available on the use of Norbit Injection in patients with kidney disease. Please consult your doctor. warnings Liver CONSULT YOUR DOCTOR There is limited information available on the use of Norbit Injection in patients with liver disease. Please consult your doctor.

Combinib 250mg Tablet is used in the treatment of breast cancer. It works by stopping or slowing down the growth of cancer cells. It is either used alone or in combination with some other medicine to cure advanced-stage breast cancer. Combinib 250mg Tablet should be taken on an empty stomach or an hour before or 2 hours after a meal. The dose and duration vary according to the severity of your condition and your response to treatment. Take it exactly as prescribed to avoid serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include nausea, headache, back pain, and breathing difficulty. It may cause severe diarrhea, drink plenty of fluids or consult with your doctor if it bothers you. You may be asked for regular monitoring of blood pressure while taking this medicine. Inform your doctor if you notice a severe headache, confusion, problems with your eyesight, nausea, or vomiting. Your doctor may check your liver function before, during, and after treatment with this medicine. Before taking Combinib 250mg Tablet, let your doctor know if you have liver or kidney problems. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are taking. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details. Uses of Combinib Tablet Pancreatic cancer Small cell lung cancer Liver cancer Kidney cancer Thyroid cancer Blood cancer (Chronic myeloid leukaemia) Gastrointestinal stromal tumour Cancer of colon and rectum Non-small cell lung cancer Soft tissue sarcoma Chronic idiopathic myelofibrosis Breast cancer Side effects of Combinib Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Combinib Abdominal pain Back pain Breathing problems Constipation Cough Diarrhea Fatigue Headache Hot flashes Increased bilirubin in the blood Insomnia (difficulty in sleeping) Joint pain Liver damage Loss of appetite Mucosal inflammation Nausea Pain in extremities Rash Stomatitis (Inflammation of the mouth) Vomiting Weakness Weight gain How to use Combinib Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Combinib 250mg Tablet is to be taken empty stomach. How Combinib Tablet works Combinib 250mg Tablet is an anti-cancer medication. It works against the HER2 (human epidermal growth factor receptor protein) receptors and EGFRs (epidermal growth factor receptor) which are responsible for the over-proliferation of cells. This is how it inhibits the growth of cancerous cells causing downstream signaling pathways. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Combinib 250mg Tablet. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Combinib 250mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding UNSAFE Combinib 250mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. warnings Driving UNSAFE Combinib 250mg Tablet may cause side effects which could affect your ability to drive. warnings Kidney CAUTION Combinib 250mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Combinib 250mg Tablet may be needed. Please consult your doctor. Limited information is available on the use of Combinib 250mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease. warnings Liver CAUTION Combinib 250mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Combinib 250mg Tablet may be needed. Please consult your doctor. Limited information is available on the use of this medicine in patients with the severe liver disease.

Marketer Hetero Healthcare Limited SALT COMPOSITION Fulvestrant (250mg) Storage Store in a refrigerator (2 - 8°C). Do not freeze. Uses of Fulzos Injection Breast cancer Product introduction Fulzos 250mg Injection is an estrogen blocker. It is used in the treatment of breast cancer in women who have gone through menopause. It works by adjusting the level of estrogen and slow down the growth of cancer cells. Fulzos 250mg Injection is given as an injection into the muscles under the supervision of a doctor. It should be taken as doctor your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. The most common side effects of this medicine include injection site reaction, headache, vomiting, allergic reaction, and nausea. If these bother you, or appear serious, let your doctor know. There may be ways of reducing or preventing them. Before taking this medicine, tell your doctor if you ever had kidney or liver disease or had bleeding disorder or had any blood clotting medicine. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant, planning pregnancy or breastfeeding. Side effects of Fulzos Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Fulzos Nausea Vomiting Back pain Fatigue Hot flashes Decreased appetite Constipation Bone pain Joint pain Cough Injection site pain Headache Pain in extremity Musculoskeletal (bone, muscle or joint) pain Breathlessness Increased alanine aminotransferase Increased aspartate aminotransferase Weakness How to use Fulzos Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Fulzos Injection works Fulzos 250mg Injection blocks the action of estrogen on breast cancer cells. This can lower or stop the growth of some breast cancer cells that need estrogen to grow. Safety advice warnings Alcohol CAUTION Caution is advised when consuming alcohol with Fulzos 250mg Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Fulzos 250mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding UNSAFE Fulzos 250mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. warnings Driving SAFE Fulzos 250mg Injection does not usually affect your ability to drive. warnings Kidney CAUTION Fulzos 250mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Fulzos 250mg Injection may be needed. Please consult your doctor. Limited information is available on the use of Fulzos 250mg Injection in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease. warnings Liver CAUTION Fulzos 250mg Injection should be used with caution in patients with liver disease. Dose adjustment of Fulzos 250mg Injection may be needed. Please consult your doctor.

Marketer Getwell Pharma (I) Pvt Ltd SALT COMPOSITION Oxaliplatin (50mg) Storage Store below 30°C Uses of Xylotin Injection Ovarian cancer Small cell lung cancer Cervical cancer Testicular cancer Cancer of colon and rectum Lung cancer Product introduction Xylotin 50mg Injection is used in the treatment of cancer of colon and rectum. It shows its working by stopping or slowing down the growth of cancer cells. Xylotin 50mg Injection is given as an injection into vein by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Nausea, fatigue, vomiting, and diarrhea are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. It may cause some serious allergic reaction, inform your doctor if you notice sore lips or mouth ulcers, rash, itching and difficulty breathing. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels. Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It makes men infertile, hence men should take doctor advice about the freezing of sperm before the treatment. You must avoid driving after taking this medicine as it may cause dizziness. Side effects of Xylotin Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Xylotin Abdominal pain Injection site reaction Weight gain Conjunctivitis Fever Nosebleeds Hair loss Constipation Skin disorder Decreased appetite Infection Peripheral sensory neuropathy Inflammation of the nose Pain Increased transaminase level in blood Increased alkaline phosphatase level in blood Taste change Edema (swelling) Lacrimation disorder Allergic reaction Fatigue Nausea Vomiting Diarrhea Stomatitis (Inflammation of the mouth) Anemia (low number of red blood cells) Decreased white blood cell count (neutrophils) Low blood platelets Headache Breathlessness How to use Xylotin Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Xylotin Injection works Xylotin 50mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and multiplication. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Xylotin 50mg Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Xylotin 50mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding UNSAFE Xylotin 50mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. warnings Driving UNSAFE Xylotin 50mg Injection may cause side effects which could affect your ability to drive. Xylotin 50mg Injection treatment may result in an increased risk of dizziness, nausea, and vomiting, and other neurological symptoms that affect walking and this may affect your ability to drive. warnings Kidney CAUTION Xylotin 50mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Xylotin 50mg Injection may be needed. Please consult your doctor. Limited information is available on the use of Xylotin 50mg Injection in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease. warnings Liver CAUTION Xylotin 50mg Injection should be used with caution in patients with liver disease. Dose adjustment of Xylotin 50mg Injection may be needed. Please consult your doctor.

Marketer Getwell Pharma (I) Pvt Ltd SALT COMPOSITION Irinotecan (100mg) Storage Store below 25°C Uses of Rinowel Injection Ovarian cancer Small cell lung cancer Cervical cancer Cancer of colon and rectum Uses of Rinowel Injection Ovarian cancer Small cell lung cancer Cervical cancer Cancer of colon and rectum Side effects of Rinowel Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Rinowel Fatigue Nausea Vomiting Weakness Hair loss Fever Anemia (low number of red blood cells) Diarrhea Decreased white blood cell count (neutrophils) Decreased appetite Mucosal inflammation How to use Rinowel Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Rinowel Injection works Rinowel 100mg Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase I) involved in DNA multiplication of the cancer cells. This slows the growth of cancer cells and eventually kills them. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Rinowel 100mg Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Rinowel 100mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding UNSAFE Rinowel 100mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. warnings Driving UNSAFE Rinowel 100mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. warnings Kidney SAFE IF PRESCRIBED Rinowel 100mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Rinowel 100mg Injection may not be needed in these patients. Please consult your doctor. Use of this medicine is not recommended for patients on dialysis. warnings Liver CONSULT YOUR DOCTOR There is limited information available on the use of Rinowel 100mg Injection in patients with liver disease. Please consult your doctor.