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'lactic acidosis accumulation'

Items tagged with 'lactic acidosis accumulation'

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Hepatitis Medicine

Tafero 25mg Tablet is an antiviral medication containing the active constituent Tenofovir alafenamide. It is used to treat chronic hepatitis B virus (HBV) infection. Hepatitis B is an infection affecting the liver caused by the hepatitis B virus. Discuss with your doctor about the precautions needed to avoid infecting others. Tell your doctor if you have or have ever had kidney diseases, liver diseases, or HIV before taking Tafero 25mg Tablet. Administration of this medicine may lead to lactic acidosis (accumulation of excessive acid) and hepatomegaly (enlarged liver). It is not recommended for patients weighing less than 35 kg. This medicine contains lactose. Contact your doctor if you are intolerant to sugars before taking medicine. Tell your doctor if you are breastfeeding or pregnant before taking Tafero 25mg Tablet. Do not stop taking this medicine without your doctor’s advice, as it may worsen the condition. The safety and efficacy of this medication in pediatric patients may differ from those in adults. Dosage adjustments and careful monitoring may be necessary for children and the elderly.

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HIV/AIDS

Introduction to Tafero 25mg Tablet Tafero 25mg Tablet is an antiviral medication containing the active constituent Tenofovir alafenamide. It is used to treat chronic hepatitis B virus (HBV) infection. Hepatitis B is an infection affecting the liver caused by the hepatitis B virus. Discuss with your doctor about the precautions needed to avoid infecting others. Tell your doctor if you have or have ever had kidney diseases, liver diseases, or HIV before taking Tafero 25mg Tablet. Administration of this medicine may lead to lactic acidosis (accumulation of excessive acid) and hepatomegaly (enlarged liver). It is not recommended for patients weighing less than 35 kg. This medicine contains lactose. Contact your doctor if you are intolerant to sugars before taking medicine. Tell your doctor if you are breastfeeding or pregnant before taking Tafero 25mg Tablet. Do not stop taking this medicine without your doctor’s advice, as it may worsen the condition. The safety and efficacy of this medication in pediatric patients may differ from those in adults. Dosage adjustments and careful monitoring may be necessary for children and the elderly. Uses of Tafero 25mg Tablet Tafero 25mg Tablet is used in the treatment of: Hepatitis B virus (HBV) infection Therapeutic Effects of Tafero 25mg Tablet Its therapeutic effect of Tafero 25mg Tablet involves reducing viral replication, lowering a viral load, preserving the immune system, and delaying disease progression in individuals with HIV-1 or HBV. Interaction of Tafero 25mg Tablet with other drugs Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Tafero 25mg Tablet, reducing effectiveness by causing undesirable side effects. More Information about Tafero 25mg Tablet Store at temprature between 20°C to 25°C (68°F to 77°F). Keep away from moisture, heat, and light. It should not be frozen. Keep it in its original packaging. Keep away from children and pets. How to consume Tafero 25mg Tablet To consume Tafero 25mg Tablet properly, follow your healthcare provider's instructions regarding dosage, frequency, and duration. Take it with or without food, swallowing the tablets or capsules with water. Adhere to the prescribed dosing schedule; do not alter the dosage without consulting your healthcare provider. Safety Advices for Tafero 25mg Tablet Image Not Available Pregnancy If you are pregnant or planning to become pregnant, it is crucial to consult with your healthcare provider before taking Tafero 25mg Tablet. Image Not Available Breast Feeding Tafero 25mg Tablet is excreted into human breast milk, but the potential risks to the infant are not well established. So it is better to consult a doctor before taking it. Image Not Available Lungs If you have a history of lung disease or are experiencing respiratory symptoms while taking, it is important to consult your healthcare provider for a thorough evaluation before taking Tafero 25mg Tablet. Image Not Available Liver The safety of Tafero 25mg Tablet in individuals with liver disease may depend on the specific type and severity of liver disease and other factors. It is important to consult with a healthcare provider Image Not Available Alcohol It is generally recommended to avoid excessive alcohol consumption while taking Tafero 25mg Tablet or any medication. Alcohol can interact with this medication and affect liver function. Image Not Available Driving People may experience side effects such as dizziness, drowsiness, or fatigue while taking Tafero 25mg Tablet. Suppose you experience any of these side effects or any other symptoms that may interfere with your ability to drive safely. In that case, avoid driving or operating heavy machinery. Side Effects of Tafero 25mg Tablet Tafero 25mg Tablet causes some side effects like all medications, although not everyone will experience them. Serious: Too much lactic acid in the blood (unusual weakness, muscle pain, cold hands and feet) Severe liver problems (yellow skin and eyes, tea-colored urine, light-colored stools, loss of appetite) Severe kidney problems Common: Nausea, vomiting Diarrhea Stomach pain, joint pain Rash, itching Feeling tired Headache, dizziness

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Cats and Dogs

Chronic kidney disease is a common kidney disorder in adult and aged dogs and cats. The gradual decline in kidney function leads to an accumulation of toxins normally cleared by the kidneys, resulting in uremia. Renodis is a combination of prebiotic and probiotic bacteria that helps to normalize gut dysbiosis, a condition that happens when there is an imbalance between good and bad bacteria in the gut. Renodis contains 3 live therapeutic bacteria that have been validated in patients with kidney disease. Renodis performs natural enteric dialysis by helping to restore the balance of bacteria in the gut. It can further help to slow down uremic toxin build-up in patients with renal insufficiency

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Eye Care

Tobi-D (Tobramycin with Dexamethasone) Eye Drops is a prescription ophthalmic solution combining an antibiotic and a corticosteroid to treat specific bacterial eye infections accompanied by inflammation. ________________________________________ ✅ Primary Uses Tobi-D is primarily used for: • Bacterial Conjunctivitis: Infection of the conjunctiva (the membrane covering the white part of the eye and the inner surface of the eyelids). • Keratitis: Infection of the cornea. • Post-surgical Infections: Prophylactic treatment or management of infections following eye surgeries. It addresses both the infection and the inflammation associated with these conditions. ________________________________________ 💊 Dosage and Administration • Standard Dosage: Instill 1–2 drops into the affected eye(s) every 4–6 hours, or as directed by your healthcare provider. • Application Tips: o Wash your hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. ________________________________________ ⚠️ Contraindications and Cautions • Contraindications: o Hypersensitivity to tobramycin, dexamethasone, or any component of the formulation. o Active viral infections of the eye, such as herpes simplex keratitis. o Untreated fungal or mycobacterial infections of the eye. • Cautions: o Use with caution in patients with a history of glaucoma, as corticosteroids can increase intraocular pressure. o Prolonged use may lead to cataract formation or secondary ocular infections. o Consult your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. ________________________________________ 🧪 Mechanism of Action • Tobramycin: An aminoglycoside antibiotic that inhibits bacterial protein synthesis, leading to bacterial cell death. • Dexamethasone: A corticosteroid that reduces inflammation by inhibiting the release of inflammatory mediators. Together, these components address both the infection and the inflammation associated with certain eye conditions.

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Eye Care

Tobi (Tobramycin Ophthalmic Solution) is a prescription antibiotic eye drop used to treat bacterial infections of the eye. It contains 0.3% tobramycin, a broad-spectrum aminoglycoside antibiotic effective against various gram-positive and gram-negative bacteria. ________________________________________ ✅ Primary Uses • Bacterial Conjunctivitis: Infection of the conjunctiva (the membrane covering the white part of the eye and the inner surface of the eyelids). • Blepharitis: Inflammation of the eyelid margins, often associated with bacterial infection. • Keratitis: Infection of the cornea. • Post-surgical Infections: Prophylactic treatment or management of infections following eye surgeries. Tobramycin ophthalmic solution is typically used alone or in combination with other medications, depending on the severity and type of infection . ________________________________________ 💊 Dosage and Administration • Standard Dosage: Instill 1–2 drops into the affected eye every 4 hours during the day. • Severe Infections: In some cases, the dosage may be increased to 2 drops every hour, as directed by a healthcare provider . • Application Tips: o Wash hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If wearing contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: • Hypersensitivity to tobramycin or any component of the formulation . • Cautions: o Use with caution in pregnant or breastfeeding women; consult a healthcare provider before use . o Prolonged use may lead to the development of resistant bacteria. o Should not be used in children without medical supervision. ________________________________________

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Eye Care

SGOS-5 (Sodium Chloride 5% Ophthalmic Solution) is a hypertonic saline eye drop primarily used to treat corneal edema—a condition where the cornea swells due to fluid accumulation, leading to blurred vision and discomfort. ________________________________________ 🔍 Uses • Corneal Edema Management: SGOS-5 helps reduce swelling in the cornea by drawing out excess fluid, thereby improving vision clarity. Post-Surgical Care: It is commonly used after eye surgeries like cataract operations to alleviate corneal swelling. • Treatment of Corneal Disorders: Conditions such as Fuchs' dystrophy or bullous keratopathy, which cause fluid buildup in the cornea, can be managed with SGOS-5. ________________________________________ 💧 Dosage and Administration • Typical Dosage: Instill 1–2 drops into the affected eye(s) every 3 to 4 hours, or as directed by your healthcare provider. • Application Tips: 1. Wash your hands thoroughly before use. 2. Tilt your head back and gently pull down the lower eyelid to form a pocket. 3. Squeeze the prescribed number of drops into the pocket. 4. Close your eye and apply gentle pressure to the inner corner for 1–2 minutes to prevent drainage. 5. Avoid touching the dropper tip to any surface to maintain sterility. ________________________________________ ⚠️ Side Effects and Precautions • Common Side Effects: o Temporary burning or stinging upon application. o Mild irritation or redness. • Temporary blurred vision. • Serious Side Effects: o Persistent eye pain or swelling. o Worsening of vision. • Signs of an allergic reaction (rash, itching, swelling). • Precautions: o Use under medical supervision, especially if you have thyroid disorders. o Not recommended for use in infants under one month of age. o Avoid concurrent use with other antiseptic eye drops containing mercury-based preservatives or sodium thiosulfate.

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General Medicine

Pipracan 4.5 Injection is a combination antibiotic medication containing Piperacillin (4 g) and Tazobactam (0.5 g). This formulation is used to treat a wide range of serious bacterial infections that may not respond to other antibiotics. ________________________________________ 🔹 Common Uses Pipracan 4.5 Injection is prescribed for: • Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) • Urinary tract infections (UTIs) • Intra-abdominal infections (e.g., peritonitis) • Skin and soft tissue infections, including diabetic foot infections • Gynecological infections, such as uterine infections • Bone and joint infections • Bloodstream infections (bacteremia) It is also used for prophylactic treatment in surgical procedures to prevent infections. ________________________________________ 🔹 How It Works • Piperacillin is a broad-spectrum penicillin antibiotic that inhibits bacterial cell wall synthesis, leading to bacterial cell death. • Tazobactam is a beta-lactamase inhibitor that protects piperacillin from degradation by beta-lactamase enzymes produced by certain bacteria, thereby enhancing its efficacy. This combination allows Pipracan 4.5 to target a wide array of bacteria, including those resistant to other antibiotics. ________________________________________ 🔹 Administration Pipracan 4.5 Injection is administered intravenously by a healthcare professional. The dosage and duration of treatment depend on the type and severity of the infection, as well as the patient's medical condition. Self-administration is not recommended. ________________________________________ 🔹 Side Effects Common side effects may include: • Nausea or vomiting • Diarrhea • Rash or itching • Pain, redness, or swelling at the injection site Serious side effects are rare but can include allergic reactions, liver enzyme abnormalities, or blood disorders. Seek immediate medical attention if you experience symptoms like difficulty breathing, swelling of the face or throat, or unusual bruising or bleeding. ________________________________________ 🔹 Precautions Before using Pipracan 4.5 Injection, inform your doctor if you have: Allergies to penicillins or beta-lactam antibiotics • Kidney or liver disease • A history of gastrointestinal diseases, such as colitis • Bleeding disorders • Undergoing dialysisUse during pregnancy and breastfeeding should be discussed with your healthcare provider. The medication should only be used if the potential benefits justify the potential risks.

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General Medicine

Nor-ADR Injection is a brand of Noradrenaline (Norepinephrine) Bitartrate Injection, manufactured by American Remedies. It is primarily used in critical care settings to manage severe hypotension (low blood pressure) and shock. ________________________________________ ✅ Primary Uses Nor-ADR Injection is indicated for: • Septic Shock: A life-threatening condition caused by severe infection leading to dangerously low blood pressure. • Cardiogenic Shock: A state where the heart is unable to pump sufficient blood to meet the body's needs. Anaphylactic Shock: A severe allergic reaction causing a sudden drop in blood pressure. • Hypotension During Surgery or Trauma: To maintain adequate blood pressure during and after surgical procedures or traumatic events. • Cardiac Arrest: As an adjunct in the management of cardiac arrest to improve blood flow to vital organs. These indications are supported by clinical guidelines and pharmacological references. ________________________________________ ⚙️ Mechanism of Action Noradrenaline is a potent vasopressor that works by: Alpha-1 Adrenergic Receptor Activation: Causing vasoconstriction, which increases systemic vascular resistance and raises blood pressure. • Beta-1 Adrenergic Receptor Activation: Increasing heart rate and myocardial contractility, thereby enhancing cardiac output. This dual action helps restore blood pressure and improve perfusion to vital organs in shock states. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Administration: Should be administered intravenously under strict medical supervision, typically in an intensive care unit (ICU) setting. • Monitoring: Continuous monitoring of blood pressure and heart rate is essential during administration. • Contraindications: Should not be used in patients with mesenteric or peripheral vascular thrombosis unless absolutely necessary. Common Side Effects: • Hypertension (high blood pressure) • Headache Nausea • Anxiety • Dizziness Serious Side Effects: • Arrhythmias (irregular heartbeats) • Tissue necrosis at the injection site • Reduced renal perfusion leading to renal failure Immediate medical attention is required if any serious side effects occur.

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