Marketer BDR Pharmaceuticals Internationals Pvt SALT COMPOSITION Rucaparib (300mg) Uses of Bdparib Tablet Sickle cell anemia Ovarian cancer Prostate cancer Blood cancer (Acute lymphocytic leukemia) Soft tissue sarcoma Hodgkin’s disease Product introduction Bdparib 300 Tablet is used in the treatment of prostate and ovarian cancers. It works by stopping the repair of damaged cancer cells, which stops their further growth, and kills the damaged cancer cells. Bdparib 300 Tablet can be taken with or without food, but better to have it at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as advised by the doctor. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include increased liver enzymes, decreased appetite, anemia, weakness, gastrointestinal disturbance, acute myeloid leukemia (blood cancer), and nasopharyngitis (inflammation of the throat and nasal passages). Inform your doctor if you notice fever, chills, sore throat, and severe diarrhea. Regular blood tests are required to check your blood cells along with the heart, liver, and blood uric acid levels. It is advised to stay hydrated while taking this medicine to overcome diarrhea. Before taking it, tell your doctor if you have heart disease, liver or kidney problems, or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine, so let your healthcare team know about all the medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Effective contraception by both males and females during the treatment is important to avoid pregnancy. Benefits of Bdparib Tablet In Ovarian cancer Ovarian cancer is a cancer that begins in the female organs that produce eggs (ovaries). This type of cancer is usually detected very late and can be fatal too. It usually spreads to the pelvis and stomach. Bdparib 300 Tablet kills the cancer cells and also prevents the repair of damaged cancer cells. It is an effective medicine but has some side effects that may be bothersome. Consult your doctor to know about the ways that can help you avoid these side effects. Side effects of Bdparib Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Bdparib Nasopharyngitis (inflammation of the throat and nasal passages) Rash Increased liver enzymes Decreased appetite Anemia (low number of red blood cells) Weakness Gastrointestinal disturbance Myelodysplastic syndrome Acute myeloid leukemia (blood cancer) How to use Bdparib Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bdparib 300 Tablet may be taken with or without food, but it is better to take it at a fixed time. How Bdparib Tablet works Bdparib 300 Tablet prevents (by blocking certain proteins) cancer cells from repairing their damaged DNA, causing them to die. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Bdparib 300 Tablet. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Bdparib 300 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Marketer BDR Pharmaceuticals Internationals Pvt SALT COMPOSITION Rucaparib (200mg) Uses of Bdparib Tablet Sickle cell anemia Ovarian cancer Prostate cancer Blood cancer (Acute lymphocytic leukemia) Soft tissue sarcoma Hodgkin’s disease Benefits of Bdparib Tablet In Ovarian cancer Ovarian cancer is a cancer that begins in the female organs that produce eggs (ovaries). This type of cancer is usually detected very late and can be fatal too. It usually spreads to the pelvis and stomach. Bdparib 200 Tablet kills the cancer cells and also prevents the repair of damaged cancer cells. It is an effective medicine but has some side effects that may be bothersome. Consult your doctor to know about the ways that can help you avoid these side effects. Side effects of Bdparib Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Bdparib Nasopharyngitis (inflammation of the throat and nasal passages) Rash Increased liver enzymes Decreased appetite Anemia (low number of red blood cells) Weakness Gastrointestinal disturbance Myelodysplastic syndrome Acute myeloid leukemia (blood cancer) How to use Bdparib Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bdparib 200 Tablet may be taken with or without food, but it is better to take it at a fixed time. How Bdparib Tablet works Bdparib 200 Tablet prevents (by blocking certain proteins) cancer cells from repairing their damaged DNA, causing them to die. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Bdparib 200 Tablet. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Bdparib 200 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. warnings Breast feeding CONSULT YOUR DOCTOR Bdparib 200 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. warnings Driving CONSULT YOUR DOCTOR It is not known whether Bdparib 200 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. warnings Kidney SAFE IF PRESCRIBED Bdparib 200 Tablet is safe to use in patients with kidney disease. No dose adjustment of Bdparib 200 Tablet is recommended. warnings Liver SAFE IF PRESCRIBED Bdparib 200 Tablet is safe to use in patients with liver disease. No dose adjustment of Bdparib 200 Tablet is recommended.

Marketer Samarth Life Sciences Pvt Ltd SALT COMPOSITION Leuprolide (22.5mg) Salt Synonyms Leuprorelin Storage Store in a refrigerator (2 - 8°C). Do not freeze. Uses of Leulide Injection Prostate cancer Endometriosis Uterine fibroids Precocious puberty (premature puberty) Female infertility Product introduction Leulide Depot 22.5mg Injection is used in the treatment of prostate cancer. It is also used to treat endometriosis (endometrium of the uterus grows excessively and causes symptoms like pain, heavy or irregular periods), uterine fibroids and central precocious puberty (very early puberty). Leulide Depot 22.5mg Injection is given as an injection under the skin by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Decreased libido, increased sweating, fatigue, muscle weakness, and hot flashes are some very common side effects of this medicine. The long-term use of medicine may cause weakened bones and a reduction in bone mineral density. You are advised to take vitamin D and calcium supplements while taking this medicine. It might cause menstrual periods to stop for a period of 7- 12 weeks, inform your doctor if menstrual bleeding continues even during the treatment. Before taking this medicine, inform your doctor if you have a history of drinking alcohol, smoking, and osteoporosis. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. Side effects of Leulide Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Leulide Decreased libido Testicular atrophy Increased sweating Fatigue Muscle weakness Erectile dysfunction Hot flashes How to use Leulide Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Leulide Injection works Leulide Depot 22.5mg Injection reduces the amount of sex hormones (testosterone in men and estrogen in women). It works by decreasing the blood levels of testosterone in males. Leulide Depot 22.5mg Injection also acts by shutting off hormones made by the ovaries (female reproductive organs), so the estrogen (one of the hormones that causes females to have periods) level is lowered.

Marketer Sun Pharmaceutical Industries Ltd SALT COMPOSITION Leuprolide (11.25mg) Salt Synonyms Leuprorelin Storage Store below 25°C Uses of Lupride Injection Prostate cancer Endometriosis Uterine fibroids Precocious puberty (premature puberty) Female infertility Product introduction Lupride Depot 11.25mg Injection is used in the treatment of prostate cancer. It is also used to treat endometriosis (endometrium of the uterus grows excessively and causes symptoms like pain, heavy or irregular periods), uterine fibroids and central precocious puberty (very early puberty). Lupride Depot 11.25mg Injection is given as an injection under the skin by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Decreased libido, increased sweating, fatigue, muscle weakness, and hot flashes are some very common side effects of this medicine. The long-term use of medicine may cause weakened bones and a reduction in bone mineral density. You are advised to take vitamin D and calcium supplements while taking this medicine. It might cause menstrual periods to stop for a period of 7- 12 weeks, inform your doctor if menstrual bleeding continues even during the treatment. Before taking this medicine, inform your doctor if you have a history of drinking alcohol, smoking, and osteoporosis. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. Side effects of Lupride Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Lupride Decreased libido Testicular atrophy Increased sweating Fatigue Muscle weakness Erectile dysfunction Hot flashes How to use Lupride Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Lupride Injection works Lupride Depot 11.25mg Injection reduces the amount of sex hormones (testosterone in men and estrogen in women). It works by decreasing the blood levels of testosterone in males. Lupride Depot 11.25mg Injection also acts by shutting off hormones made by the ovaries (female reproductive organs), so the estrogen (one of the hormones that causes females to have periods) level is lowered.

Clindacan 600 Injection is a brand of Clindamycin 600 mg/4 ml Injection, manufactured by American Remedies. Clindamycin is a lincosamide antibiotic used to treat various serious bacterial infections. ________________________________________ 🩺 Uses of Clindacan 600 Injection Clindacan 600 Injection is indicated for the treatment of: • Lower Respiratory Tract Infections: Such as pneumonia, empyema, and lung abscesses caused by susceptible organisms. • Skin and Soft Tissue Infections: Including cellulitis, abscesses, and wound infections. • Bone and Joint Infections: Such as osteomyelitis and septic arthritis. • Intra-abdominal Infections: Including peritonitis and intra-abdominal abscesses. • Pelvic Inflammatory Disease: Infections of the female reproductive organs. • Septicemia (Bloodstream Infection): Blood poisoning caused by bacteria. • Endocarditis: Infection of the heart valves. • Dental Infections: Such as dental abscesses. • Malaria: In combination with quinine for the treatment of multi-drug-resistant Plasmodium falciparum infection. ________________________________________ 💊 Mechanism of Action Clindamycin works by binding to the 50S subunit of bacterial ribosomes, inhibiting protein synthesis and thereby preventing bacterial growth. It is effective against gram-positive cocci and anaerobic bacteria. ________________________________________ ⚠️ Precautions Before administering Clindacan 600 Injection, inform your healthcare provider if you have: • A history of gastrointestinal diseases, especially colitis. • Liver or kidney disease. • Allergies to clindamycin or other lincosamide antibiotics. • Asthma, eczema, or hay fever.

Clindacan 300 Injection is a brand name for Clindamycin 300 mg/2 ml Injection, manufactured by Hills Pharmaceuticals. Clindamycin is a lincosamide antibiotic used to treat various serious bacterial infections. ________________________________________ 🩺 Uses of Clindacan 300 Injection Clindacan 300 Injection is prescribed for the treatment of: • Lower Respiratory Tract Infections: Such as pneumonia and empyema. Skin and Soft Tissue Infections: Including cellulitis and abscesses. • Bone and Joint Infections: Like osteomyelitis and septic arthritis. • Intra-abdominal Infections: Including peritonitis and abscesses. • Pelvic Inflammatory Disease: Infections of the female reproductive organs. • Septicemia (Bloodstream Infections): Blood poisoning caused by bacteria. Endocarditis: Infection of the heart valves. • Dental Infections: Such as dental abscesses. • Malaria: In combination with quinine for the treatment of multi-drug-resistant Plasmodium falciparum infection. ________________________________________ 💊 Mechanism of Action Clindamycin works by inhibiting bacterial protein synthesis, thereby stopping bacterial growth. It is effective against gram-positive cocci and anaerobic bacteria. ________________________________________ ⚠️ Precautions Before using Clindacan 300 Injection, inform your healthcare provider if you have: • A history of gastrointestinal diseases, especially colitis. • Liver or kidney disease. • Allergies to clindamycin or other lincosamide antibiotics. Asthma, eczema, or hay fever. This medication should be administered under the supervision of a healthcare professional.

Ceforzone SB 1.5 Injection is a combination antibiotic formulation containing Cefoperazone (1000 mg) and Sulbactam (500 mg). Manufactured by American Remedies, it is primarily used to treat a wide range of bacterial infections. ________________________________________ 🩺 Uses of Ceforzone SB 1.5 Injection Ceforzone SB 1.5 Injection is indicated for the treatment of various bacterial infections, including: • Respiratory Tract Infections: Such as pneumonia and bronchitis. • Urinary Tract Infections: Including cystitis and pyelonephritis. • Intra-abdominal Infections: Such as peritonitis and abscesses. • Skin and Soft Tissue Infections: Including cellulitis and wound infections. • Bone and Joint Infections: Such as osteomyelitis and septic arthritis. • Meningitis: Infection of the membranes covering the brain and spinal cord. • Pelvic Inflammatory Disease: Infection of the female reproductive organs. • Gonorrhea: A sexually transmitted infection. Septicemia: Bloodstream infection. Surgical Prophylaxis: To prevent infections associated with major surgeries. ________________________________________ 💊 Mechanism of Action • Cefoperazone: A third-generation cephalosporin antibiotic that inhibits the synthesis of the bacterial cell wall, leading to cell lysis and death. Sulbactam: A beta-lactamase inhibitor that protects cefoperazone from enzymatic degradation by bacterial beta-lactamases, thereby enhancing its antibacterial activity. ________________________________________ ⚠️ Precautions • Allergy: Inform your healthcare provider if you have a history of allergic reactions to penicillins, cephalosporins, or beta-lactam antibiotics. • Liver or Kidney Impairment: Use with caution in patients with liver or kidney dysfunction. Dosage adjustments may be necessary. • Pregnancy and Breastfeeding: Consult your doctor before use during pregnancy or breastfeeding. • Drug Interactions: Inform your healthcare provider about all other medications you are taking to avoid potential interactions.

Aone SB 1.5 gm Injection is a combination antibiotic manufactured by American Remedies. It contains Ceftriaxone (1000 mg) and Sulbactam (500 mg). Ceftriaxone is a third-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis, leading to cell death. Sulbactam is a β-lactamase inhibitor that protects Ceftriaxone from degradation by β-lactamase-producing bacteria, thereby enhancing its effectiveness. ________________________________________ 🩺 Uses of Aone SB 1.5 gm Injection Aone SB 1.5 gm Injection is prescribed for the treatment of various bacterial infections, including: • Lower Respiratory Tract Infections: Such as pneumonia. • Urinary Tract Infections (UTIs): Including both complicated and uncomplicated UTIs. • Intra-abdominal Infections: Such as peritonitis. • Skin and Soft Tissue Infections: Including cellulitis and abscesses. • Bone and Joint Infections: Such as osteomyelitis and septic arthritis. • Septicemia: Bloodstream infections. • Meningitis: Infections of the brain and spinal cord membranes. • Pelvic Inflammatory Disease: Infections of the female reproductive organs. • Endocarditis: Infection of the heart valves. • Surgical Prophylaxis: To prevent infections during or after surgery. ________________________________________ 💊 How It Works Ceftriaxone works by inhibiting the synthesis of bacterial cell walls, leading to the destruction of the bacteria. Sulbactam enhances the activity of Ceftriaxone by inhibiting β-lactamase enzymes that can degrade Ceftriaxone, thereby extending its spectrum of activity against resistant bacteria. ________________________________________ ⚠️ Side Effects Common side effects may include: • Injection site reactions (pain, redness, or swelling). • Diarrhea. • Rash. • Increased liver enzymes. • Low blood platelets. • Changes in white blood cell counts. If any of these side effects persist or worsen, consult your healthcare provider promptly. ________________________________________ ⚠️ Precautions Before using Aone SB 1.5 gm Injection, inform your doctor if you: • Have a history of allergies to cephalosporin antibiotics. • Have liver or kidney disease. • Are pregnant, planning to become pregnant, or breastfeeding. • Are taking any other medications, including over-the-counter drugs and supplements. Your doctor will determine the appropriate dosage and duration of treatment based on your specific condition.

Aone 2 gm Injection is an antibiotic medication manufactured by American Remedies. It contains Ceftriaxone, a third-generation cephalosporin antibiotic, and is used to treat a wide range of bacterial infections. ________________________________________ 🩺 Uses of Aone 2 gm Injection Aone 2 gm Injection is prescribed for the treatment of various bacterial infections, including: • Lower Respiratory Tract Infections: Such as pneumonia and bronchitis. • Urinary Tract Infections (UTIs): Both complicated and uncomplicated. • Meningitis: Infections of the brain and spinal cord. • Skin and Soft Tissue Infections: Including abscesses and cellulitis. • Bone and Joint Infections: Such as osteomyelitis and septic arthritis. • Bloodstream Infections (Bacteremia): Including sepsis. • Pelvic Inflammatory Disease: Infections of the female reproductive organs. • Gonorrhea: A sexually transmitted infection caused by Neisseria gonorrhoeae. • Surgical Prophylaxis: To prevent infections during or after surgery. ________________________________________ 💊 How It Works Ceftriaxone works by inhibiting the synthesis of bacterial cell walls, leading to the destruction of the bacteria. It is administered either intravenously (IV) or intramuscularly (IM) under the supervision of a healthcare professional. ________________________________________ ⚠️ Side Effects Common side effects may include: • Injection site reactions (pain, redness, or swelling). • Diarrhea. • Rash. • Changes in liver function tests. • Abnormal blood cell counts (e.g., decreased white blood cells or platelets). If any of these side effects persist or worsen, consult your healthcare provider promptly. ________________________________________ 💰 Price and Availability The price of Aone 2 gm Injection varies by retailer. For instance, it is available for ₹36.8 per injection on 1mg. Prices may differ based on location and pharmacy. ________________________________________ ⚠️ Precautions Before using Aone 2 gm Injection, inform your doctor if you: • Have a history of allergies to cephalosporin antibiotics. • Have liver or kidney disease. • Are pregnant, planning to become pregnant, or breastfeeding. • Are taking any other medications, including over-the-counter drugs and supplements. Your doctor will determine the appropriate dosage and duration of treatment based on your specific condition.