Ceforzone SB 1.5 Injection is a combination antibiotic formulation containing Cefoperazone (1000 mg) and Sulbactam (500 mg). Manufactured by American Remedies, it is primarily used to treat a wide range of bacterial infections. ________________________________________ 🩺 Uses of Ceforzone SB 1.5 Injection Ceforzone SB 1.5 Injection is indicated for the treatment of various bacterial infections, including: • Respiratory Tract Infections: Such as pneumonia and bronchitis. • Urinary Tract Infections: Including cystitis and pyelonephritis. • Intra-abdominal Infections: Such as peritonitis and abscesses. • Skin and Soft Tissue Infections: Including cellulitis and wound infections. • Bone and Joint Infections: Such as osteomyelitis and septic arthritis. • Meningitis: Infection of the membranes covering the brain and spinal cord. • Pelvic Inflammatory Disease: Infection of the female reproductive organs. • Gonorrhea: A sexually transmitted infection. Septicemia: Bloodstream infection. Surgical Prophylaxis: To prevent infections associated with major surgeries. ________________________________________ 💊 Mechanism of Action • Cefoperazone: A third-generation cephalosporin antibiotic that inhibits the synthesis of the bacterial cell wall, leading to cell lysis and death. Sulbactam: A beta-lactamase inhibitor that protects cefoperazone from enzymatic degradation by bacterial beta-lactamases, thereby enhancing its antibacterial activity. ________________________________________ ⚠️ Precautions • Allergy: Inform your healthcare provider if you have a history of allergic reactions to penicillins, cephalosporins, or beta-lactam antibiotics. • Liver or Kidney Impairment: Use with caution in patients with liver or kidney dysfunction. Dosage adjustments may be necessary. • Pregnancy and Breastfeeding: Consult your doctor before use during pregnancy or breastfeeding. • Drug Interactions: Inform your healthcare provider about all other medications you are taking to avoid potential interactions.

Pipracan 4.5 Injection is a combination antibiotic medication containing Piperacillin (4 g) and Tazobactam (0.5 g). This formulation is used to treat a wide range of serious bacterial infections that may not respond to other antibiotics. ________________________________________ 🔹 Common Uses Pipracan 4.5 Injection is prescribed for: • Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) • Urinary tract infections (UTIs) • Intra-abdominal infections (e.g., peritonitis) • Skin and soft tissue infections, including diabetic foot infections • Gynecological infections, such as uterine infections • Bone and joint infections • Bloodstream infections (bacteremia) It is also used for prophylactic treatment in surgical procedures to prevent infections. ________________________________________ 🔹 How It Works • Piperacillin is a broad-spectrum penicillin antibiotic that inhibits bacterial cell wall synthesis, leading to bacterial cell death. • Tazobactam is a beta-lactamase inhibitor that protects piperacillin from degradation by beta-lactamase enzymes produced by certain bacteria, thereby enhancing its efficacy. This combination allows Pipracan 4.5 to target a wide array of bacteria, including those resistant to other antibiotics. ________________________________________ 🔹 Administration Pipracan 4.5 Injection is administered intravenously by a healthcare professional. The dosage and duration of treatment depend on the type and severity of the infection, as well as the patient's medical condition. Self-administration is not recommended. ________________________________________ 🔹 Side Effects Common side effects may include: • Nausea or vomiting • Diarrhea • Rash or itching • Pain, redness, or swelling at the injection site Serious side effects are rare but can include allergic reactions, liver enzyme abnormalities, or blood disorders. Seek immediate medical attention if you experience symptoms like difficulty breathing, swelling of the face or throat, or unusual bruising or bleeding. ________________________________________ 🔹 Precautions Before using Pipracan 4.5 Injection, inform your doctor if you have: Allergies to penicillins or beta-lactam antibiotics • Kidney or liver disease • A history of gastrointestinal diseases, such as colitis • Bleeding disorders • Undergoing dialysisUse during pregnancy and breastfeeding should be discussed with your healthcare provider. The medication should only be used if the potential benefits justify the potential risks.

Aone SB 1.5 gm Injection is a combination antibiotic manufactured by American Remedies. It contains Ceftriaxone (1000 mg) and Sulbactam (500 mg). Ceftriaxone is a third-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis, leading to cell death. Sulbactam is a β-lactamase inhibitor that protects Ceftriaxone from degradation by β-lactamase-producing bacteria, thereby enhancing its effectiveness. ________________________________________ 🩺 Uses of Aone SB 1.5 gm Injection Aone SB 1.5 gm Injection is prescribed for the treatment of various bacterial infections, including: • Lower Respiratory Tract Infections: Such as pneumonia. • Urinary Tract Infections (UTIs): Including both complicated and uncomplicated UTIs. • Intra-abdominal Infections: Such as peritonitis. • Skin and Soft Tissue Infections: Including cellulitis and abscesses. • Bone and Joint Infections: Such as osteomyelitis and septic arthritis. • Septicemia: Bloodstream infections. • Meningitis: Infections of the brain and spinal cord membranes. • Pelvic Inflammatory Disease: Infections of the female reproductive organs. • Endocarditis: Infection of the heart valves. • Surgical Prophylaxis: To prevent infections during or after surgery. ________________________________________ 💊 How It Works Ceftriaxone works by inhibiting the synthesis of bacterial cell walls, leading to the destruction of the bacteria. Sulbactam enhances the activity of Ceftriaxone by inhibiting β-lactamase enzymes that can degrade Ceftriaxone, thereby extending its spectrum of activity against resistant bacteria. ________________________________________ ⚠️ Side Effects Common side effects may include: • Injection site reactions (pain, redness, or swelling). • Diarrhea. • Rash. • Increased liver enzymes. • Low blood platelets. • Changes in white blood cell counts. If any of these side effects persist or worsen, consult your healthcare provider promptly. ________________________________________ ⚠️ Precautions Before using Aone SB 1.5 gm Injection, inform your doctor if you: • Have a history of allergies to cephalosporin antibiotics. • Have liver or kidney disease. • Are pregnant, planning to become pregnant, or breastfeeding. • Are taking any other medications, including over-the-counter drugs and supplements. Your doctor will determine the appropriate dosage and duration of treatment based on your specific condition.

INTRODUCTION ABOUT ENCORATE CHRONO 500MG TABLET ENCORATE CHRONO 500MG TABLET is a combination of Sodium valproate and Valproic acid, which belong to the group of medicines called Anticonvulsant/Antiepileptic drugs. It is used to manage epilepsy in adults and children. It is also used to manage bipolar disorders. Epilepsy is an abnormal electrical activity in the brain and nervous system. The symptoms may include temporary confusion, muscle stiffness, jerky movements in legs or arms, loss of consciousness, psychological symptoms (such as anxiety or fear), etc. ENCORATE CHRONO 500MG TABLET is not recommended for use in patients with liver problems or with a family history of liver problems, porphyria (a hereditary disease that affects the skin or nervous system), blood coagulation or clotting disorders, pancreatic diseases (inflammation of the pancreas), urea cycle disorder (a genetic disorder) or Alpers-Huttenlocher syndrome (a rare disorder that affects brain, liver & muscles), etc. ENCORATE CHRONO 500MG TABLET should be used with caution in patients with kidney problems or lung diseases (such as chronic obstructive pulmonary disease) and diabetes. ENCORATE CHRONO 500MG TABLET is also not recommended for use in pregnant and breastfeeding women. It should be used with caution in children (below 2 years of age). Consult your doctor before taking the medicine. The common side effects of taking ENCORATE CHRONO 500MG TABLET may include dizziness, headache, sleep disorders, clumsiness/unsteadiness, trembling of hands and arms and nervousness. Consult your doctor if any of the symptoms worsen or persist. USES OF ENCORATE CHRONO 500MG TABLET Manage epilepsy Manage bipolar disorders HOW ENCORATE CHRONO 500MG TABLET WORKS ENCORATE CHRONO 500MG TABLET helps in managing epilepsy, where sodium valproate and valproic acid effectively increases the GABA (a neurotransmitter/chemical messenger) concentration in the central nervous system by reducing its degradation. It also blocks certain ion channels which reduce high-frequency neuronal activity in the brain, thereby reliving seizure activity. DIRECTIONS FOR USE Take ENCORATE CHRONO 500MG TABLET as advised by your physician. Swallow the medicine with a glass of water with or after food. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition. SIDE EFFECTS OF ENCORATE CHRONO 500MG TABLET COMMON headache sleep disorders clumsiness or unsteadiness trembling of hands and arms nervousness changing moods blurred vision ringing in ears deafness dizziness flu abdominal or stomach pain heartburn nausea and vomiting diarrhoea skin rash hair loss or thinning of hair back pain change in menstrual periods lack or loss of strength mental confusion aggression convulsion memory problems becoming unreactive bedwetting signs of liver damage such as skin and eyes that appear yellowish (jaundice), abdominal pain and swelling. signs of inflammation of the pancreas (pancreatitis) such as upper abdominal pain, abdomen tenderness, fever and rapid pulse signs of Fanconi syndrome (a disorder of kidney tubes) such as excessive thirst, urination, vomiting overgrown gum tissue agitation disturbance in attention abnormal behaviour hyperactivity learning disorder UNCOMMON unusual bleeding or bruising abnormal dreams anxiety feeling sad irritability pain in joints cough constipation dry eyes spots before the eyes ear infection ear pain runny nose dental pain bloating muscle pains or stiffness tiredness weight gain or loss learning disorder coma loss of muscle control brittle bones and fractures shortness of breath chest pain blood clotting problems RARE Stop taking ENCORATE CHRONO 500MG TABLET and contact your doctor if you experience any of the following side effects: signs of allergic reactions such as swelling of the face, lips, eyelids, throat and tongue, which may cause difficulty in breathing and swallowing signs of altered levels of ammonia in the blood characterized by vomiting, balance issues and lack of alertness signs of liver problems characterized by nausea, vomiting, tiredness, sleepiness, weakness, stomach pain, yellowing of the skin or whites of the eye signs of inflammation of the pancreas characterized by acute abdominal pain chest pain shortness of breath hallucinations suicidal thoughts psychosis (mental disorder causing disconnection from reality) toxic epidermal necrolysis (life-threatening skin disorder causing widespread skin pain, rashes, blisters, sores and crusting) Steven-Johnson syndrome (a skin disorder characterized by painful rashes and blisters on the skin) anaphylaxis (severe allergic reaction characterized by shortness of breath, fainting or fastened heartbeat) erythema multiforme (a skin condition characterized by raised red rashes on the skin)

About the brand Malegra 50 is marketed globally by Sunrise. About the drug Malegra 50 Mg An active ingredient in Malegra 50 is Sildenafil citrate. Sildenafil citrate is used in the treatment for erectile dysfunction treatment (inadequate penile erection during sexual activity), pulmonary hypertension (high pressure in blood vessels of lungs), benign prostatic hyperplasia (enlarged prostate). Manufacturer of Malegra 50 Mg Malegra 50 having 50 mg of sildenafil citrate is manufactured by sunrise. It is mainly marketed and supplied by the company and its associates in India. Strength Malegra 50 having 50 mg of Sildenafil citrate. USA Brands Equivalent to Sildenafil citrate the salt in Malegra 50 Mg Viagra is the USA brand equivalent to Malegra 50 Use of Sildenafil citrate the salt in Malegra 50 Mg It is used to treat erectile dysfunction (ED). In men, it is used to treat the signs of an enlarged prostate. It is used to treat raised pressure in the lungs. It may be given to you for other reasons. Talk with the doctor. Erectile dysfunction: It is a medical condition, in which, proper erection of penis is a problem. Men are not able to erect their penis even during sexual stimulation. This leads to impotency. Malegra 50 helps in relaxing the veins and arteries in penis leading to perfect erection before sexual activity and thus increase the satisfaction level during sexual intercourse Pulmonary Arterial Hypertension: It is a condition in which there is a raised pressure in your lungs. Malegra 50 relax blood vessels in the lungs leads to lowering of blood pressure. Benign prostatic hyperplasia: it is a condition in which your prostate gland is enlarged. Malegra 50 improve the blood flow to the prostate and relax the muscles in the prostate and bladder and thus help in relieving urinary symptoms. Usually, a high dose is used for Pulmonary Arterial Hypertension than the other two indications. How Malegra 50 Mg works Malegra 50 having Sildenafil citrate works by inhibiting the phosphodiesterase type 5 in the body. Thus it stops the degradation of cGMP( Cyclic guanosine monophosphate). Availability of cGMP helps relax the veins in penis and thus helps in erection when there is a need for sexual activity or sexual stimulation. Inhibition of phosphodiesterase type 5 (PDE-5) in smooth muscle of pulmonary blood vessels results in its relaxation of and it helps to reduce the pressure in your lungs. How to take Malegra 50 Mg Malegra 50 having salt Sildenafil citrate shall be taken before 1 hour of sexual intercourse with a glass of water. More information will be directed by your doctor. Hence consult your doctor before having Malegra 50. Sildenafil Dosage Sildenafil citrate the active salt in Malegra 50 is to be taken usually in a dosage which ranges from 25 mg to 100 mg. More specific dose will be directed by your doctor. Hence, do not take Malegra 50 without consulting with your doctor. How long should Malegra 50 Mg be continued Malegra 50 having sildenafil citrate is a need to basis medicine. Consult your doctor regarding the intake and stoppage of the drug. Do not take a decision on your own. Consult your doctor for each possible steps. Dose of Malegra 50 Mg missed The possible chances of missing the dose of the drug is minimal, however, consult your doctor regarding the same. The drug is mainly taken before the actual sexual intercourse, hence missing the dose is rare. Drug interaction with Sildenafil citrate the salt in Malegra 50 Mg Nitrates(Isosorbide dinitrate, isosorbide mononitrate, nitroglycerin) generally react with Sildenafil citrate, the salt present in Malegra 50. Tell your doctor If you are taking any of these drugs: Itraconazole or ketoconazole, riociguat, or ritonavir, rifampin. If you are taking another brand that has the same active ingredient (sildenafil citrate) If you are taking another drug in the same class as of sildenafil citrate (eg: tadalafil) If you are taking any of these drugs-alfuzosin, doxazosin, silodosin, tamsulosin, terazosin When not to take Malegra 50 Mg Do not take Malegra 50 if you have allergic reactions with the salt or excipients. Sildenafil Adverse Effects / Side effects Some patients may have allergic reactions. Inform your doctor if you have any signs of allergic reaction like rash, itching, red-swollen skin, fever, trouble breathing, swollen face etc. Chest pain or pressure A fast heartbeat or a heartbeat that does not feel normal. Dizziness or passing out. Severe headache. Weakness on one side of the body, trouble speaking or thinking, loss of balance, drooping on one side of the face, or blurred eyesight. Change in eyesight. Loss of eyesight. Hearing loss or change in hearing Ringing in ears. Very bad muscle pain, back pain, soreness, or weakness. If you have a painful erection (hard penis) or an erection that lasts for longer than 4 hours, then call your doctor immediately. It should be treated properly otherwise it may cause lasting sex problems. Overdose E