Marketer Cipla Ltd SALT COMPOSITION Darunavir (800mg) + Ritonavir (100mg) Storage Store below 30°C Uses of Daruvir R Tablet Treatment of HIV infection Product introduction Daruvir 800 R Tablet is a combination of antiretrovirals medicines. It is prescribed to treat HIV (human immunodeficiency virus) infection. It boosts up the immunity to fight against HIV to manage or treat AIDS (acquired immunodeficiency syndrome). Daruvir 800 R Tablet restricts the growth of HIV in the body and reduces the risk of getting HIV-related complications to improve the lifespan of an individual. The medicine can be taken with or without food. Taking these medicines regularly at the same time increases their effectiveness. A dose of this medicine should not be missed as it can affect your recovery. It is important to complete the full course of the treatment until your doctor advises you to stop it. Sudden discontinuation of the treatment may affect the potency of the medicine. The most common side effects of this medicine are headaches, nasal congestion, diarrhea, nausea, weakness and tiredness, cough, and rash. These side effects are generally temporary, but if they persist or become serious inform your doctor. This medicine can also make you feel lazy or weak, so it is advised to avoid driving. Drinking plenty of fluid can help you to cope up with the side effects, so stay hydrated. Before starting with the treatment, you should consult your doctor if you are pregnant or breastfeeding, or have any health condition. Your doctor may suggest regular blood tests to check your blood counts, kidney and liver functions, and other health conditions. If you are HIV positive, you should not breastfeed or share personal belongings like razors or toothbrushes. Consult your doctor to know about safe sex methods in order to prevent transmission of HIV during intercourse. Benefits of Daruvir R Tablet In Treatment of HIV infection Daruvir 800 R Tablet controls HIV infection by preventing the virus from multiplying in the body. It also helps your immune system to work better and may decrease your chance of developing HIV-related illnesses such as AIDS. This ensures that you live a long and healthy life. Avoid skipping doses and follow your doctor’s instructions carefully to get maximum benefit. Taking Daruvir 800 R Tablet along with practicing safer sex and making other lifestyle changes may decrease the risk of transmitting the HIV virus to other people. Side effects of Daruvir R Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Daruvir R Diarrhea Headache Nausea Abdominal pain Rash Vomiting How to use Daruvir R Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Daruvir 800 R Tablet may be taken with or without food, but it is better to take it at a fixed time. How Daruvir R Tablet works Daruvir 800 R Tablet is a combination of two anti-HIV medicines. Altogether, Darunavir and Ritonavir work by interfering with an enzyme (protease), which is required by HIV-infected cells to make new viruses. This stops the production of new viruses. This is how it works to treat HIV infections.

Phoscut 800 Tablet is used to treat increased phosphate levels in the blood. It is used in patients who are on dialysis due to severe kidney disease. It inhibits the absorption of phosphate from the intestine and lowers the phosphate levels in the blood. Phoscut 800 Tablet should be taken with food. Take it in the dose and duration as advised by your doctor. Take it regularly and at a fixed time each day to get the maximum benefit of the medicine. Phoscut 800 Tablet may cause side effects such as nausea, vomiting, abdominal pain, constipation, and diarrhea. You may also develop low levels of calcium, folic acid, and vitamins A, D, E, and K in your blood. Take necessary supplements as advised by your doctor.

Sevcar 800 Tablet is used to treat increased phosphate levels in the blood. It is used in patients who are on dialysis due to severe kidney disease. It inhibits the absorption of phosphate from the intestine and lowers the phosphate levels in the blood. Sevcar 800 Tablet should be taken with food. Take it in the dose and duration as advised by your doctor. Take it regularly and at a fixed time each day to get the maximum benefit of the medicine. Sevcar 800 Tablet may cause side effects such as nausea, vomiting, abdominal pain, constipation, and diarrhea. You may also develop low levels of calcium, folic acid, and vitamins A, D, E, and K in your blood. Take necessary supplements as advised by your doctor.

Marketer Cipla Ltd SALT COMPOSITION Darunavir (600mg) + Ritonavir (100mg) Storage Store below 30°C Uses of Daruvir R Tablet Treatment of HIV infection Product introduction Daruvir 600 R Tablet is a combination of antiretrovirals medicines. It is prescribed to treat HIV (human immunodeficiency virus) infection. It boosts up the immunity to fight against HIV to manage or treat AIDS (acquired immunodeficiency syndrome). Daruvir 600 R Tablet restricts the growth of HIV in the body and reduces the risk of getting HIV-related complications to improve the lifespan of an individual. The medicine can be taken with or without food. Taking these medicines regularly at the same time increases their effectiveness. A dose of this medicine should not be missed as it can affect your recovery. It is important to complete the full course of the treatment until your doctor advises you to stop it. Sudden discontinuation of the treatment may affect the potency of the medicine. The most common side effects of this medicine are headaches, nasal congestion, diarrhea, nausea, weakness and tiredness, cough, and rash. These side effects are generally temporary, but if they persist or become serious inform your doctor. This medicine can also make you feel lazy or weak, so it is advised to avoid driving. Drinking plenty of fluid can help you to cope up with the side effects, so stay hydrated. Before starting with the treatment, you should consult your doctor if you are pregnant or breastfeeding, or have any health condition. Your doctor may suggest regular blood tests to check your blood counts, kidney and liver functions, and other health conditions. If you are HIV positive, you should not breastfeed or share personal belongings like razors or toothbrushes. Consult your doctor to know about safe sex methods in order to prevent transmission of HIV during intercourse. Benefits of Daruvir R Tablet In Treatment of HIV infection Daruvir 600 R Tablet controls HIV infection by preventing the virus from multiplying in the body. It also helps your immune system to work better and may decrease your chance of developing HIV-related illnesses such as AIDS. This ensures that you live a long and healthy life. Avoid skipping doses and follow your doctor’s instructions carefully to get maximum benefit. Taking Daruvir 600 R Tablet along with practicing safer sex and making other lifestyle changes may decrease the risk of transmitting the HIV virus to other people. Side effects of Daruvir R Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Daruvir R Diarrhea Headache Nausea Abdominal pain Rash Vomiting How to use Daruvir R Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Daruvir 600 R Tablet may be taken with or without food, but it is better to take it at a fixed time. How Daruvir R Tablet works Daruvir 600 R Tablet is a combination of two anti-HIV medicines. Altogether, Darunavir and Ritonavir work by interfering with an enzyme (protease), which is required by HIV-infected cells to make new viruses. This stops the production of new viruses. This is how it works to treat HIV infections.

Combinib 250mg Tablet is used in the treatment of breast cancer. It works by stopping or slowing down the growth of cancer cells. It is either used alone or in combination with some other medicine to cure advanced-stage breast cancer. Combinib 250mg Tablet should be taken on an empty stomach or an hour before or 2 hours after a meal. The dose and duration vary according to the severity of your condition and your response to treatment. Take it exactly as prescribed to avoid serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include nausea, headache, back pain, and breathing difficulty. It may cause severe diarrhea, drink plenty of fluids or consult with your doctor if it bothers you. You may be asked for regular monitoring of blood pressure while taking this medicine. Inform your doctor if you notice a severe headache, confusion, problems with your eyesight, nausea, or vomiting. Your doctor may check your liver function before, during, and after treatment with this medicine. Before taking Combinib 250mg Tablet, let your doctor know if you have liver or kidney problems. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are taking. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details. Uses of Combinib Tablet Pancreatic cancer Small cell lung cancer Liver cancer Kidney cancer Thyroid cancer Blood cancer (Chronic myeloid leukaemia) Gastrointestinal stromal tumour Cancer of colon and rectum Non-small cell lung cancer Soft tissue sarcoma Chronic idiopathic myelofibrosis Breast cancer Side effects of Combinib Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Combinib Abdominal pain Back pain Breathing problems Constipation Cough Diarrhea Fatigue Headache Hot flashes Increased bilirubin in the blood Insomnia (difficulty in sleeping) Joint pain Liver damage Loss of appetite Mucosal inflammation Nausea Pain in extremities Rash Stomatitis (Inflammation of the mouth) Vomiting Weakness Weight gain How to use Combinib Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Combinib 250mg Tablet is to be taken empty stomach. How Combinib Tablet works Combinib 250mg Tablet is an anti-cancer medication. It works against the HER2 (human epidermal growth factor receptor protein) receptors and EGFRs (epidermal growth factor receptor) which are responsible for the over-proliferation of cells. This is how it inhibits the growth of cancerous cells causing downstream signaling pathways. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Combinib 250mg Tablet. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Combinib 250mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding UNSAFE Combinib 250mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. warnings Driving UNSAFE Combinib 250mg Tablet may cause side effects which could affect your ability to drive. warnings Kidney CAUTION Combinib 250mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Combinib 250mg Tablet may be needed. Please consult your doctor. Limited information is available on the use of Combinib 250mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease. warnings Liver CAUTION Combinib 250mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Combinib 250mg Tablet may be needed. Please consult your doctor. Limited information is available on the use of this medicine in patients with the severe liver disease.

Marketer Cipla Ltd SALT COMPOSITION Abiraterone Acetate (250mg) Storage Store below 30°C Uses of Xbira Tablet Sickle cell anemia Prostate cancer Blood cancer (Acute lymphocytic leukemia) Soft tissue sarcoma Hodgkin’s disease Product introduction Xbira 250mg Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy. Xbira 250mg Tablet should not be taken on an empty stomach. Taking it with food may cause side effects. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include vomiting, decreased potassium level in blood, edema (swelling), decreased white blood cell count, fatigue and increased liver enzymes. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Other than this, yellowing of skin, loss of appetite, shortness of breath, dark urine and nausea can happen, which indicate some liver problem. Your doctor might check you for liver function, blood pressure, and the level of potassium in your blood. Before taking it, tell your doctor if have high blood pressure, heart problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment. There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details. Side effects of Xbira Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Xbira Edema (swelling) Vomiting Decreased potassium level in blood Fatigue Anemia (low number of red blood cells) Urinary tract infection Diarrhea High blood pressure Cough Joint swelling How to use Xbira Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xbira 250mg Tablet is to be taken empty stomach. How Xbira Tablet works Xbira 250mg Tablet is an anticancer medication. It works by preventing androgen (male hormone) production in man. This is done by inhibiting an enzyme (CYP17) that is responsible for the production of androgen. This is how it slows down the growth of prostate cancer.

Marketer Cipla Ltd SALT COMPOSITION Abiraterone Acetate (500mg) Storage Store below 30°C Uses of Xbira Tablet Sickle cell anemia Prostate cancer Blood cancer (Acute lymphocytic leukemia) Soft tissue sarcoma Hodgkin’s disease Product introduction Xbira 500 Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy. Xbira 500 Tablet should not be taken on an empty stomach. Taking it with food may cause side effects. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include vomiting, decreased potassium level in blood, edema (swelling), decreased white blood cell count, fatigue and increased liver enzymes. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Other than this, yellowing of skin, loss of appetite, shortness of breath, dark urine and nausea can happen, which indicate some liver problem. Your doctor might check you for liver function, blood pressure, and the level of potassium in your blood. Before taking it, tell your doctor if have high blood pressure, heart problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment. There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details. Side effects of Xbira Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Xbira Edema (swelling) Vomiting Decreased potassium level in blood Fatigue Anemia (low number of red blood cells) Urinary tract infection Diarrhea High blood pressure Cough Joint swelling How to use Xbira Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xbira 500 Tablet is to be taken empty stomach. How Xbira Tablet works Xbira 500 Tablet is an anticancer medication. It works by preventing androgen (male hormone) production in man. This is done by inhibiting an enzyme (CYP17) that is responsible for the production of androgen. This is how it slows down the growth of prostate cancer.

Cyclomune 0.05% About the brand Cyclomune is brand of Sun Pharmaceuticals having salt Cyclosporine. Sun Pharmaceuticals is one of biggest generic drug manufacturer throughout global markets. It has served more than 150 markets globally. It has more than 2000 marketed products and is the leading pharmaceutical drug company of India. About the drug Cyclomune is drug having Cyclosporine as salt. Cyclosporine eye drops work differently as compared to cyclosporine used in different dosage forms. Cyclosporine is an immunosuppressant drug. It interferes with the immune system of the body. Cyclosporine eye drops help in curing the dry eye condition when used as an ophthalmic solution. Manufacturer of the drug Cyclomune is manufactured by Sun Pharmaceutical in India. Strength of the drug The 3 ml solution of Cyclomune contains 0.5 % strength of Cyclosporine. USA equivalent brand Restasis is the US brand equivalent to Cyclomune available in USA markets. Uses of the drug Cyclomune is used for dry eye conditions. It has proven effects to cure chronic dry eye conditions. How does it work? As an eye drop, Cyclomune works as a partial modulator of the immune system. Tear production in the eyes gets lowered due to the accumulation of dead lymphocytes cells in tear glands. Cyclomune eye drops works by reversing the cycle and hence helps in increasing the tear production from tear glands. How to take the drug? Take the medicine as directed by your physician. It should be taken twice in a day with a gap of 12 hours in between in both eyes. Efforts shall be made to take the drug drops the same time every day. Dosage needed Cyclomune eye drops shall be taken twice in a day. For correct dosage take your physician advice and guidelines. How long should drug to be continued? It shall be continued as directed by your doctor. Do not overdose yourself with the eye drops. What if you miss the dosage? Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not instill a double dose to make up for a missed one. Drug interaction with other More than 800 drug interactions have been reported with use of Cyclosporine. It interacts with atorvastatin, aspirin, Calcium 600 D, docusate, amlodipine, pregabalin, Zyrtec etc. When not to take the drug Avoid taking the drug if you are allergic to any of the constituents of the drug Cyclomune. Consult your doctor for further advise. Side effects of intake Side effects associated with the drug are, burning, itching, stinging, redness, or pain of the eyes overflow of tears red eyes eye discharge blurred vision or other vision changes feeling that something is in the eye Overdose effects Shaking, headache, dizziness, unusual growth of body hair, nausea/vomiting, diarrhea, stomach upset, flushing or Unusual growth and swelling of the gums may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. General information and precautions Do not let anyone else use your medication. Ask your pharmacist any doubts you have about refilling your prescription. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. carry this list with you every time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.