DARCEPT 40MG INJECTION belongs to the class of medication called 'blood-forming agent' primarily used to treat anaemia (low red blood cell count) in person with long-term serious (chronic) kidney disease and persons receiving chemotherapy for some types of cancer (except for bone marrow or blood cells' cancer). DARCEPT 40MG INJECTION helps to reverse anaemia and reduce the need for blood transfusion. Anaemia occurs when the body has a lower amount of red blood cells or haemoglobin. In chronic kidney disease, the kidney gets damaged and doesn't filter the blood, leading to anaemia. DARCEPT 40MG INJECTION contains a protein 'Darbepoetin alfa' which works by providing signals to the bone marrow to make more red blood cells. DARCEPT 40MG INJECTION is a biologic response modifier and erythropoiesis-stimulating protein. In chronic kidney disease, when the kidney fails to produce sufficient 'erythropoietin protein' which aids in the formation of red blood cells, DARCEPT 40MG INJECTION stimulates the production of this protein in the bone marrow. DARCEPT 40MG INJECTION will be injected by the healthcare provider. Do not self-administer. The most common side effects of DARCEPT 40MG INJECTION are shortness of breath, cough, low blood pressure during dialysis, headache, body aches, diarrhoea, injection site pain and abdominal pain. Most of these sides effects of DARCEPT 40MG INJECTION do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Zynesp 200 mcg Injection belongs to the class of medication called 'blood-forming agent' primarily used to treat anaemia (low red blood cell count) in person with long-term serious (chronic) kidney disease and persons receiving chemotherapy for some types of cancer (except for bone marrow or blood cells' cancer). Zynesp 200 mcg Injection helps to reverse anaemia and reduce the need for blood transfusion. Anaemia occurs when the body has a lower amount of red blood cells or haemoglobin. In chronic kidney disease, the kidney gets damaged and doesn't filter the blood, leading to anaemia. Zynesp 200 mcg Injection contains a protein 'Darbepoetin alfa' which works by providing signals to the bone marrow to make more red blood cells. Zynesp 200 mcg Injection is a biologic response modifier and erythropoiesis-stimulating protein. In chronic kidney disease, when the kidney fails to produce sufficient 'erythropoietin protein' which aids in the formation of red blood cells, Zynesp 200 mcg Injection stimulates the production of this protein in the bone marrow. Zynesp 200 mcg Injection will be injected by the healthcare provider. Do not self-administer. The most common side effects of Zynesp 200 mcg Injection are shortness of breath, cough, low blood pressure during dialysis, headache, body aches, diarrhoea, injection site pain and abdominal pain. Most of these sides effects of Zynesp 200 mcg Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. If you have uncontrolled/untreated high blood pressure or red cell aplasia (a type of anaemia) due to darbepoetin alfa or epoetin alfa, please inform your doctor before taking Zynesp 200 mcg Injection to avoid any complications. Also, mention all the other medications you are taking to affect the way Zynesp 200 mcg Injection works. Inform your doctor immediately, if you feel weak, lightheaded, tired, or short of breath, or if your skin looks pale as it may be signs that the body has stopped responding to Zynesp 200 mcg Injection .

FLURACIL 250MG INJECTION contains Fluorouracil, which belongs to a group of medicines called Nucleoside metabolic inhibitors. FLURACIL 250MG INJECTION is used to manage cancer involving the breast, oesophagus, stomach, colon, rectum, pancreas, prostate, ovary, bladder, and head and neck cancer. FLURACIL 250MG INJECTION should not be used in patients with serious infections (for example, Herpes zoster or chickenpox), non-malignant tumours, poor nutrition, weakened immunity due to long illness, damaged bone marrow due to other antineoplastics or radiotherapy, severe liver disease, or homozygotic or complete deficiency of dihydropyrimidine dehydrogenase (DPD) enzyme. FLURACIL 250MG INJECTION should be used with caution in patients with decreased blood cells, oral ulcers, fever or haemorrhage at any site or weakness (due to decreased blood cells), kidney or liver problems like jaundice (yellowing of the skin) or heart problems like chest pain, reduced activity or deficiency of the enzyme DPD (dihydropyrimidine dehydrogenase), had high-dose radiation to pelvic, spine, ribs, metastatic tumours with involvement of bone marrow, severe bone marrow suppression include neutropenia, thrombocytopenia, and anaemia, viral, bacterial, fungal and/or parasitic infections, encephalopathy, gastrointestinal side effects like stomatitis, diarrhoea, bleeding from the G.I. tract or haemorrhage at any site, family history of partial or complete deficiency of the enzyme dihydropyrimidine dehydrogenase (DPD), had recent major surgery.

Marketer BDR Pharmaceuticals Internationals Pvt SALT COMPOSITION Rucaparib (300mg) Uses of Bdparib Tablet Sickle cell anemia Ovarian cancer Prostate cancer Blood cancer (Acute lymphocytic leukemia) Soft tissue sarcoma Hodgkin’s disease Product introduction Bdparib 300 Tablet is used in the treatment of prostate and ovarian cancers. It works by stopping the repair of damaged cancer cells, which stops their further growth, and kills the damaged cancer cells. Bdparib 300 Tablet can be taken with or without food, but better to have it at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as advised by the doctor. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include increased liver enzymes, decreased appetite, anemia, weakness, gastrointestinal disturbance, acute myeloid leukemia (blood cancer), and nasopharyngitis (inflammation of the throat and nasal passages). Inform your doctor if you notice fever, chills, sore throat, and severe diarrhea. Regular blood tests are required to check your blood cells along with the heart, liver, and blood uric acid levels. It is advised to stay hydrated while taking this medicine to overcome diarrhea. Before taking it, tell your doctor if you have heart disease, liver or kidney problems, or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine, so let your healthcare team know about all the medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Effective contraception by both males and females during the treatment is important to avoid pregnancy. Benefits of Bdparib Tablet In Ovarian cancer Ovarian cancer is a cancer that begins in the female organs that produce eggs (ovaries). This type of cancer is usually detected very late and can be fatal too. It usually spreads to the pelvis and stomach. Bdparib 300 Tablet kills the cancer cells and also prevents the repair of damaged cancer cells. It is an effective medicine but has some side effects that may be bothersome. Consult your doctor to know about the ways that can help you avoid these side effects. Side effects of Bdparib Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Bdparib Nasopharyngitis (inflammation of the throat and nasal passages) Rash Increased liver enzymes Decreased appetite Anemia (low number of red blood cells) Weakness Gastrointestinal disturbance Myelodysplastic syndrome Acute myeloid leukemia (blood cancer) How to use Bdparib Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bdparib 300 Tablet may be taken with or without food, but it is better to take it at a fixed time. How Bdparib Tablet works Bdparib 300 Tablet prevents (by blocking certain proteins) cancer cells from repairing their damaged DNA, causing them to die. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Bdparib 300 Tablet. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Bdparib 300 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Marketer BDR Pharmaceuticals Internationals Pvt SALT COMPOSITION Rucaparib (200mg) Uses of Bdparib Tablet Sickle cell anemia Ovarian cancer Prostate cancer Blood cancer (Acute lymphocytic leukemia) Soft tissue sarcoma Hodgkin’s disease Benefits of Bdparib Tablet In Ovarian cancer Ovarian cancer is a cancer that begins in the female organs that produce eggs (ovaries). This type of cancer is usually detected very late and can be fatal too. It usually spreads to the pelvis and stomach. Bdparib 200 Tablet kills the cancer cells and also prevents the repair of damaged cancer cells. It is an effective medicine but has some side effects that may be bothersome. Consult your doctor to know about the ways that can help you avoid these side effects. Side effects of Bdparib Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Bdparib Nasopharyngitis (inflammation of the throat and nasal passages) Rash Increased liver enzymes Decreased appetite Anemia (low number of red blood cells) Weakness Gastrointestinal disturbance Myelodysplastic syndrome Acute myeloid leukemia (blood cancer) How to use Bdparib Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bdparib 200 Tablet may be taken with or without food, but it is better to take it at a fixed time. How Bdparib Tablet works Bdparib 200 Tablet prevents (by blocking certain proteins) cancer cells from repairing their damaged DNA, causing them to die. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Bdparib 200 Tablet. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Bdparib 200 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. warnings Breast feeding CONSULT YOUR DOCTOR Bdparib 200 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. warnings Driving CONSULT YOUR DOCTOR It is not known whether Bdparib 200 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. warnings Kidney SAFE IF PRESCRIBED Bdparib 200 Tablet is safe to use in patients with kidney disease. No dose adjustment of Bdparib 200 Tablet is recommended. warnings Liver SAFE IF PRESCRIBED Bdparib 200 Tablet is safe to use in patients with liver disease. No dose adjustment of Bdparib 200 Tablet is recommended.

INTRODUCTION ABOUT TAXONAB 100MG INJECTION TAXONAB 100MG INJECTION contains Paclitaxel which belongs to a group of anti-cancer medicines called Taxanes. TAXONAB 100MG INJECTION is used to manage ovarian and breast cancer as a first line of therapy and as a second line of management when platinum containing medicines (such as cisplatin) or anthracyclines are insufficient to manage the disease in affected individuals. TAXONAB 100MG INJECTION is also used to manage advanced NSCLC (non-small cell lung cancer) when surgery/radiation therapy is not suitable. The medicine is also indicated for use to manage AIDS-related Kaposi’s sarcoma when other managements (such as anthracyclines) are insufficient to manage the disease in affected individuals. TAXONAB 100MG INJECTION is not recommended for use in patients allergic to paclitaxel and polyoxyethylated castor oil. It is also not recommended for use in patients with few white blood cells count and serious & uncontrolled infection. The medicine is also not used in patients suffering from severe liver disease. Before receiving TAXONAB 100MG INJECTION, inform your doctor if you had previously received radiation to your chest and/or suffering from thrombocytopenia (low platelet count)/acute infections (such as herpes zoster, chickenpox, herpes), kidney problems (such as chronic kidney disease), liver problems (such as mild/moderate hepatic impairment) and/or heart problems (such as severe coronary artery disease, myocardial infarction and arrhythmias). TAXONAB 100MG INJECTION is not recommended for use during pregnancy. Women of child-bearing potential should use effective contraception method while receiving TAXONAB 100MG INJECTION which should be continued for next-6 months after completing the management. The medicine is also not recommended for use in breastfeeding women. TAXONAB 100MG INJECTION is also not recommended for use in children and adolescents (aged below 18 years). The medicine can be used with caution in elderly patients (aged above 65 years) after consulting the doctor. The most common side effects of receiving TAXONAB 100MG INJECTION are minor allergic reactions (such as flushing, rash, itching), shortness of breath, sore throat/mouth ulcers, diarrhea, nausea, vomiting and/or loss of hair. Consult your doctor if any of these symptoms worsen. USES OF TAXONAB 100MG INJECTION Manage ovarian and breast cancer. Manage advanced NSCLC (non-small cell lung cancer) Manage AIDS-related Kaposi’s sarcoma in affected individuals. HOW TAXONAB 100MG INJECTION WORKS TAXONAB 100MG INJECTION works by interfering with the microtubule structures in the cell (substance which aids cancer cells to divide and multiply) thus inhibiting the growth of cancer cells and managing its spread in affected individuals. DIRECTIONS FOR USE TAXONAB 100MG INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF TAXONAB 100MG INJECTION COMMON minor allergic reactions such as flushing, rash and/or itching infections such as upper respiratory infection, urinary tract infection shortness of breath sore throat/mouth ulcers, sore and red mouth diarrhea, nausea, vomiting loss of hair pain in the muscles, cramps, joints fever, severe chills, headache, dizziness, tiredness, looking pale bleeding, bruising more easily than normal signs of peripheral neuropathy such as numbness, tingling/weakness in arms and legs temporary mild nail change and skin changes reactions at injection sites such as localized swelling, pain and/or redness of the skin. UNCOMMON septic shock (severe drop in blood pressure) due to infections racing heartbeat, rapid beating of the heart, respiratory distress, heart attack, heart block fatigue, sweating, fainting, significant allergic reactions, phlebitis (inflammation of a vein), swelling of the face, lips, mouth, tongue and/or throat back pain, chest pain, pain around hands and feet, chills, abdominal pain. RARE febrile neutropenia (type of fever) due to low white blood cell count associated with fever and increased risk of infection motor neuropathy (disease that affects your body’s motor nerves) pulmonary embolism (blockade of lung artery), lung fibrosis (damaged/scarred lung tissue), interstitial pneumonia (scarring of lung tissue), pleural effusion (build of fluid between lungs and chest) bowel obstruction, bowel perforation, inflammation of colon, inflammation of the pancreas (pancreatitis) skin redness peritonitis (inflammation of abdominal layer) fever, dehydration, weakness anaphylactic reactions (life threatening allergic reaction). HOW TO MANAGE SIDE EFFECTS Diarrhea: Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult your doctor and inform them if the symptom gets worse.

Obparp 150 Tablet is a prescription medicine used in the treatment of ovarian and breast cancer. It works by blocking an enzyme called PARP, which helps fix damaged DNA. By stopping PARP, the medicine prevents cancer cells from repairing themselves, leading them to die off and slowing tumor growth. Obparp 150 Tablet may be taken with or without food. Swallow the tablets whole, without crushing, chewing, or splitting them. Take it regularly and at the same time every day to maintain an even level of the medication in your body. Follow your doctor’s instructions on the exact dosage and schedule. Common side effects include nausea, fatigue, vomiting, loss of appetite, diarrhea, and dizziness. If you experience nausea or vomiting, eating smaller, more frequent meals and staying hydrated can help. Inform your doctor if these side effects become severe or do not go away. Be cautious about driving or operating heavy machinery if you feel dizzy or fatigued.

Bracanat 150mg Tablet is a prescription medicine used in the treatment of ovarian and breast cancer. It works by blocking an enzyme called PARP, which helps fix damaged DNA. By stopping PARP, the medicine prevents cancer cells from repairing themselves, leading them to die off and slowing tumor growth. Bracanat 150mg Tablet may be taken with or without food. Swallow the tablets whole, without crushing, chewing, or splitting them. Take it regularly and at the same time every day to maintain an even level of the medication in your body. Follow your doctor’s instructions on the exact dosage and schedule. Common side effects include nausea, fatigue, vomiting, loss of appetite, diarrhea, and dizziness. If you experience nausea or vomiting, eating smaller, more frequent meals and staying hydrated can help. Inform your doctor if these side effects become severe or do not go away. Be cautious about driving or operating heavy machinery if you feel dizzy or fatigued.

Lynza Tablet is a prescription medicine used in the treatment of ovarian and breast cancer. It works by blocking an enzyme called PARP, which helps fix damaged DNA. By stopping PARP, the medicine prevents cancer cells from repairing themselves, leading them to die off and slowing tumor growth. Lynza Tablet may be taken with or without food. Swallow the tablets whole, without crushing, chewing, or splitting them. Take it regularly and at the same time every day to maintain an even level of the medication in your body. Follow your doctor’s instructions on the exact dosage and schedule. Common side effects include nausea, fatigue, vomiting, loss of appetite, diarrhea, and dizziness. If you experience nausea or vomiting, eating smaller, more frequent meals and staying hydrated can help. Inform your doctor if these side effects become severe or do not go away. Be cautious about driving or operating heavy machinery if you feel dizzy or fatigued.