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'cystic fibrosis'

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General Medicine

Mucanix Injection is a brand of Acetylcysteine Injection, manufactured by American Remedies. Acetylcysteine is a mucolytic agent that helps in thinning and loosening mucus in the airways, making it easier to cough up and clear the airways. ________________________________________ ✅ Primary Uses Mucanix Injection is primarily used for: • Respiratory Disorders: Conditions such as chronic bronchitis, asthma, and cystic fibrosis, where there is excessive mucus production. • Paracetamol (Acetaminophen) Overdose: As an antidote to prevent liver damage when administered within 8 hours of overdose. ________________________________________ ⚙️ Mechanism of Action Acetylcysteine works by: • Breaking down mucus: It reduces the viscosity of mucus, facilitating easier expectoration. • Restoring glutathione levels: In cases of paracetamol overdose, it replenishes glutathione, a vital antioxidant, aiding in detoxification and protecting the liver. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Allergy: Do not use if allergic to acetylcysteine or any of its components. • Asthma: Use with caution in patients with asthma; monitoring is required. • Pregnancy and Breastfeeding: Consult a doctor before use during pregnancy or breastfeeding. Common Side Effects: • Nausea • Vomiting • Rash • Fever • Headache Serious Side Effects: • Anaphylactic reactions (rare) • Hypotension • Tachycardia If you experience any of these serious side effects, seek immediate medical attention.

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General Medicine

Colistican 3 Injection is an intravenous formulation containing Colistimethate Sodium 3 Million IU, manufactured by American Remedies. It is primarily used to treat severe infections caused by multidrug-resistant Gram-negative bacteria. ________________________________________ 🩺 Uses of Colistican 3 Injection Colistican 3 Injection is indicated for: • Ventilator-Associated Pneumonia (VAP): A lung infection acquired during mechanical ventilation. • Bloodstream Infections (Sepsis): Infections caused by resistant bacteria entering the bloodstream. • Urinary Tract Infections (UTIs): Caused by multidrug-resistant Gram-negative organisms. • Intra-abdominal Infections: Such as peritonitis. • Cystic Fibrosis: For chronic pulmonary infections due to Pseudomonas aeruginosa in both adults and children. ________________________________________ 💊 Mechanism of Action Colistimethate sodium is a prodrug that, upon administration, is converted to colistin. Colistin binds to the bacterial cell membrane, disrupting its structure and leading to cell death. It is particularly effective against aerobic Gram-negative bacteria with hydrophobic outer membranes. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Renal Function: Use with caution in patients with kidney impairment. • Neurological Effects: Monitor for signs of neurotoxicity, including dizziness and muscle weakness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Injection site reactions • Renal toxicity • Neurological symptoms (e.g., confusion, dizziness) • Gastrointestinal disturbances (e.g., nausea, vomiting) • Muscle weakness

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Antibiotic Medicine

Colistican 1 Injection is a brand of Colistimethate Sodium for Injection manufactured by American Remedies. Colistimethate sodium is a polymyxin-class antibiotic, also known as polymyxin E, used to treat serious infections caused by multidrug-resistant Gram-negative bacteria. ________________________________________ 🩺 Uses of Colistican 1 Injection Colistican 1 Injection is primarily used for: • Multidrug-Resistant Infections: Especially those caused by Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae. • Ventilator-Associated Pneumonia (VAP): A lung infection acquired during mechanical ventilation. • Urinary Tract Infections (UTIs): Caused by resistant Gram-negative bacteria. • Bloodstream Infections (Sepsis): Resulting from resistant pathogens. • Intra-abdominal Infections: Such as peritonitis. • Cystic Fibrosis: For chronic pulmonary infections due to Pseudomonas aeruginosa in both adults and children. ________________________________________ 💊 Mechanism of Action Colistimethate sodium is a prodrug that, upon administration, is converted to colistin. Colistin binds to the bacterial cell membrane, disrupting its structure and leading to cell death. It is particularly effective against aerobic Gram-negative bacteria with hydrophobic outer membranes. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Renal Function: Use with caution in patients with kidney impairment. • Neurological Effects: Monitor for signs of neurotoxicity, including dizziness and muscle weakness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Injection site reactions • Renal toxicity • Neurological symptoms (e.g., confusion, dizziness) • Gastrointestinal disturbances (e.g., nausea, vomiting) • Muscle weakness

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General Medicine

Acetylcysteine (N-Acetylcysteine or NAC) Injection is a medication with various clinical uses, particularly in treating acute poisoning and respiratory conditions. It is the injectable form of NAC, which is also available in oral and inhalation formulations. 🔹 Common Uses of Acetylcysteine Injection (NAC Injection): 💊 Acetaminophen (Paracetamol) Overdose: Primary and well-established use: Acetylcysteine is the antidote for acetaminophen toxicity (overdose). It works by replenishing glutathione, a crucial antioxidant in the liver, thus preventing liver damage caused by acetaminophen metabolism. Early administration is key: Can prevent or minimize liver damage if administered within 8–10 hours of overdose. 🫁 Chronic Obstructive Pulmonary Disease (COPD) / Respiratory Conditions: Mucolytic action: NAC helps to break down and thin mucus in the lungs, making it easier to cough up. Often used in COPD, chronic bronchitis, asthma, and other conditions where thick mucus obstructs airways. Nebulized NAC is sometimes used for inhalation to directly treat respiratory conditions. 🧬 Kidney Protection (Preventing Contrast-Induced Nephropathy): Prophylactic use in patients who are at high risk of contrast-induced kidney damage (e.g., before receiving contrast media in imaging procedures like CT scans). NAC may help protect kidney function from damage caused by the contrast agents used during these procedures. 🔬 Antioxidant Therapy in Critical Care: NAC is used as an antioxidant to reduce oxidative stress in various conditions such as sepsis, acute respiratory distress syndrome (ARDS), and other critical illnesses. It helps to reduce inflammation and cell damage by neutralizing free radicals. 🧪 Treatment of Cystic Fibrosis (CF): While primarily in oral or nebulized form, acetylcysteine may sometimes be used intravenously to help manage mucus buildup in the airways in CF patients, although this is less common. 🍸 Alcohol-Induced Liver Injury: NAC has been investigated in treating alcohol-induced liver damage, as it helps with glutathione replenishment and reduces oxidative stress. It’s sometimes used in the hospital setting for patients with alcoholic liver disease. 💉 How It’s Administered: Intravenously (IV) is the most common method for acetaminophen overdose or critical care. It is usually given as a slow infusion, with the dosage adjusted based on the severity of the condition being treated (e.g., for acetaminophen toxicity, a specific dosing regimen is followed). ⚠️ Precautions & Side Effects: Common Side Effects: Nausea or vomiting (especially with high doses) Rash Fever Hypotension (low blood pressure) during IV administration Severe Reactions: Rarely, an allergic reaction (e.g., anaphylaxis) may occur. Bronchospasm (tightening of the airways) in patients with a history of asthma, though this is less common with IV use. Kidney function should be monitored, especially in patients at high risk of renal issues or those receiving contrast agents. ✅ Summary of Acetylcysteine Injection Uses: Condition Use of Acetylcysteine (NAC) Injection Acetaminophen overdose ✅ Primary antidote Mucolytic (thinning mucus) for respiratory conditions ✅ COPD, chronic bronchitis, asthma Kidney protection in contrast nephropathy ✅ Prevent contrast-induced kidney damage Antioxidant therapy in critical care ✅ Sepsis, ARDS, oxidative stress Cystic Fibrosis (mucus management) ✅ Less common, but used Alcohol-induced liver injury ✅ Investigational (glutathione replenishment)

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Hepatitis Medicine

Velasof tablet contains the active components Sofosbuvir and Velpatasvir. It is used to treat chronic hepatitis C. Hepatitis C is a liver infection caused by the hepatitis C virus (HCV). The treatment duration is often shorter than older treatment regimens. The duration can vary depending on factors such as HCV genotype, previous treatment history, and the presence of liver cirrhosis. Successful treatment with Velasof tablet can significantly reduce liver inflammation and fibrosis caused by HCV infection. By achieving viral eradication, the risk of developing liver cirrhosis, liver failure, and hepatocellular carcinoma (a type of liver cancer) can be substantially reduced. If you have a known allergy or hypersensitivity to Velasof tablet or any of the components of the medication, you should not take it. The safety and efficacy of sofosbuvir and velpatasvir combination therapy have not been established in children under 18. Its use in the pediatric population is currently limited. It is recommended to use alternative treatment options or adjust the dosage in these cases.

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Respiratory

Pirfenex Tablet is a prescription medicine used in the treatment of idiopathic pulmonary fibrosis. It reduces scarring and swelling in the lungs and helps to breathe better. Pirfenex Tablet is best taken with food. Take it at the same time every day to get the most benefits. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. The most common side effects of this medicine include insomnia, headache, dizziness, dyspepsia, nausea, diarrhea, and photosensitivity. To overcome dizziness, avoid driving or attention-seeking activity. Some people may experience weight loss and other side effects. Monitor your weight regularly or ask for the doctor's advice in such cases. Your doctor also may perform a liver function test while on treatment with this medicine.

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Respiratory

Cyendiv 150mg Soft Gelatin Capsule is used in the treatment of idiopathic pulmonary fibrosis and non-small cell lung cancer. It works by targeting certain pathways involved in the growth and progression of these diseases and helps to stop or slow the spread of cancer cells. Cyendiv 150mg Soft Gelatin Capsule should be taken with food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

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Respiratory

Cyendiv 100mg Soft Gelatin Capsule is used in the treatment of idiopathic pulmonary fibrosis and non-small cell lung cancer. It works by targeting certain pathways involved in the growth and progression of these diseases and helps to stop or slow the spread of cancer cells. Cyendiv 100mg Soft Gelatin Capsule should be taken with food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Diarrhea is a very common side effect of this medicine. You are advised to drink plenty of fluids and inform your doctor if it does not go away. Other common side effects include nausea, abdominal pain, vomiting, abnormal liver function tests, loss of appetite, headache, weight loss, and high blood pressure. Your doctor might ask you for some blood tests to monitor liver functioning.

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Heart Disorder

Prostal 500mcg Injection Salt Composition : Alprostadil Manufacturer : CELON LABORATORIES LTD Introduction to Prostal 500mcg Injection Prostal 500mcg injection contains active components called Alprostadil. This medication is often used to treat ED in men with difficulty achieving or maintaining an erection. It may be used to improve blood flow in patients with peripheral arterial disease (PAD), a condition in which blood flow to the extremities (usually the legs) is reduced. In newborns with certain heart conditions, such as PDA, it can open a blood vessel called the ductus arteriosus. It can also be used in diagnostic tests to assess blood flow in specific body areas, such as during penile Doppler ultrasound studies to evaluate erectile function. Individuals who have a known allergy or hypersensitivity to Alprostadil or any of its components should not use the medication. It should be avoided in men with penile implants or conditions that make penile injections unsafe, such as penile fibrosis, curvature, or priapism (prolonged erections). It should not be used in individuals with conditions predisposing them to priapism, such as sickle cell anemia, multiple myeloma, or leukemia. It should not be used in individuals who experience unexplained genital or pelvic pain, as it may indicate an underlying medical condition. Individuals with bleeding disorders or those taking anticoagulant medications (blood thinners) should use Prostal 500mcg injection cautiously, as it may increase the risk of bleeding at the injection site. It should not be used concomitantly with alpha-blocker medications used to treat conditions like benign prostatic hyperplasia (BPH) and high blood pressure, as it can lead to severe low blood pressure. It should not be used in infants with congenital heart defects who have conditions that are worsened by increased blood flow to the lungs. It can be used in elderly patients, but caution may be required. Uses of Prostal 500mcg Injection Erectile dysfunction (ED) Peripheral arterial disease (PAD) Patent ductus arteriosus (PDA) in Infants Diagnostic testing Therapeutic Effects of Prostal 500mcg Injection Prostal 500mcg injection binds to specific receptors on smooth muscle cells in blood vessels and various tissues. When it binds to these receptors, it triggers biochemical events that lead to vasodilation. It relaxes the smooth muscles in blood vessel walls, particularly in the penis, when used for erectile dysfunction. It involves promoting the relaxation of smooth muscle cells, improving blood flow to specific body areas, depending on its intended use. Interaction of Prostal 500mcg Injection with other drugs Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Prostal 500mcg injection, reducing effectiveness by causing undesirable side effects. More Information about Prostal 500mcg Injection Store at room temperature below 20 to 25°C Keep away from moisture, heat, and light. It should not be frozen. Keep away from children and pets. How to consume Prostal 500mcg Injection Prostal 500mcg injection can be administered via various routes, depending on the medical condition. For erectile dysfunction (ED), it can be injected directly into the penis (intracavernosal injection), applied topically to the penile tip (urethral application), or used as a urethral suppository. Safety Advices for Prostal 500mcg Injection Image Not Available Pregnancy If you are pregnant or trying to become pregnant, it is important to talk to your doctor before taking Prostal 500mcg injection. Image Not Available Breast Feeding There is limited research on the safety of Prostal 500mcg injection in breastfeeding women. It is important to talk to your doctor before taking this medication. Image Not Available Lungs If you have lung diseases, talking to your doctor before taking Prostal 500mcg injection is important. Image Not Available Liver Prostal 500mcg injection is metabolized in the liver, so individuals with severe liver disease may require dose adjustments. Patients with liver problems should discuss their condition with their healthcare provider before using it. Image Not Available Alcohol It is unsafe to drink alcohol while taking Prostal 500mcg injection. Excessive alcohol consumption can increase the risk of certain side effects. Image Not Available Driving Prostal 500mcg injection can cause dizziness or fainting, especially if low blood pressure occurs. If you experience any side effects, consult your healthcare provider before taking it while driving. Side Effects of Prostal 500mcg Injection Prostal 500mcg injection causes some side effects like all medications, although not everyone will experience them. Serious: Priapism Penile fibrosis Allergic reactions Low blood pressure Cardiovascular effects Bleeding Common:

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