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'contrast agents'

Items tagged with 'contrast agents'

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General Medicine

Acetylcysteine (N-Acetylcysteine or NAC) Injection is a medication with various clinical uses, particularly in treating acute poisoning and respiratory conditions. It is the injectable form of NAC, which is also available in oral and inhalation formulations. 🔹 Common Uses of Acetylcysteine Injection (NAC Injection): 💊 Acetaminophen (Paracetamol) Overdose: Primary and well-established use: Acetylcysteine is the antidote for acetaminophen toxicity (overdose). It works by replenishing glutathione, a crucial antioxidant in the liver, thus preventing liver damage caused by acetaminophen metabolism. Early administration is key: Can prevent or minimize liver damage if administered within 8–10 hours of overdose. 🫁 Chronic Obstructive Pulmonary Disease (COPD) / Respiratory Conditions: Mucolytic action: NAC helps to break down and thin mucus in the lungs, making it easier to cough up. Often used in COPD, chronic bronchitis, asthma, and other conditions where thick mucus obstructs airways. Nebulized NAC is sometimes used for inhalation to directly treat respiratory conditions. 🧬 Kidney Protection (Preventing Contrast-Induced Nephropathy): Prophylactic use in patients who are at high risk of contrast-induced kidney damage (e.g., before receiving contrast media in imaging procedures like CT scans). NAC may help protect kidney function from damage caused by the contrast agents used during these procedures. 🔬 Antioxidant Therapy in Critical Care: NAC is used as an antioxidant to reduce oxidative stress in various conditions such as sepsis, acute respiratory distress syndrome (ARDS), and other critical illnesses. It helps to reduce inflammation and cell damage by neutralizing free radicals. 🧪 Treatment of Cystic Fibrosis (CF): While primarily in oral or nebulized form, acetylcysteine may sometimes be used intravenously to help manage mucus buildup in the airways in CF patients, although this is less common. 🍸 Alcohol-Induced Liver Injury: NAC has been investigated in treating alcohol-induced liver damage, as it helps with glutathione replenishment and reduces oxidative stress. It’s sometimes used in the hospital setting for patients with alcoholic liver disease. 💉 How It’s Administered: Intravenously (IV) is the most common method for acetaminophen overdose or critical care. It is usually given as a slow infusion, with the dosage adjusted based on the severity of the condition being treated (e.g., for acetaminophen toxicity, a specific dosing regimen is followed). ⚠️ Precautions & Side Effects: Common Side Effects: Nausea or vomiting (especially with high doses) Rash Fever Hypotension (low blood pressure) during IV administration Severe Reactions: Rarely, an allergic reaction (e.g., anaphylaxis) may occur. Bronchospasm (tightening of the airways) in patients with a history of asthma, though this is less common with IV use. Kidney function should be monitored, especially in patients at high risk of renal issues or those receiving contrast agents. ✅ Summary of Acetylcysteine Injection Uses: Condition Use of Acetylcysteine (NAC) Injection Acetaminophen overdose ✅ Primary antidote Mucolytic (thinning mucus) for respiratory conditions ✅ COPD, chronic bronchitis, asthma Kidney protection in contrast nephropathy ✅ Prevent contrast-induced kidney damage Antioxidant therapy in critical care ✅ Sepsis, ARDS, oxidative stress Cystic Fibrosis (mucus management) ✅ Less common, but used Alcohol-induced liver injury ✅ Investigational (glutathione replenishment)

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Cats and Dogs

Essential Oto® is a physiological cleanser specifically designed for the regular hygiene of dogs, cats or rabbits’ ears(Excess earwax, Earwax plugs, Bad odors). Based on active ingredients of 100% natural origin, it helps eliminate excessive earwax and debris while deodorizing ear canals. It also has a hydrating and soothing action. Thanks to its alcohol-free formula and its mild ceruminolytic agents, Essential Oto® is perfectly adapted to the maintenance of healthy ears even the most sensitive. Its use is facilitated thanks to a twist-off service cap allowing a single-handed opening. Its transparent bottle enables to check the integrity of the formula throughout the product’s lifespan.

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Eye Care

Tropind Plus is a combination ophthalmic solution containing Tropicamide 0.8% and Phenylephrine 5%. This formulation is primarily used for both diagnostic and therapeutic purposes in ophthalmology. 🩺 Primary Uses of Tropind Plus 1. Pupillary Dilation (Mydriasis): The combination of Tropicamide and Phenylephrine effectively dilates the pupil, allowing eye care professionals to conduct thorough examinations of the retina, optic nerve, and other internal structures. 2. Cycloplegia: Tropicamide paralyzes the ciliary muscle, preventing accommodation (focusing), which is useful in refractive error assessments. 3. Uveitis Management: In cases of uveitis, Tropind Plus helps alleviate pain and prevents further spasms of the eye muscles. 4. Preoperative Preparation: Before surgeries like cataract extraction or retinal procedures, dilating the pupil is essential for clear visualization of the posterior segment. 5. Retinal Imaging: Facilitates procedures such as fundus photography and optical coherence tomography (OCT) by ensuring adequate pupil dilation. ⚙️ How It Works • Tropicamide is a parasympatholytic agent that inhibits the contraction of the circular muscle and paralyzes the ciliary muscle, leading to pupil dilation and cycloplegia. Phenylephrine is a sympathomimetic drug that causes contraction of the radial muscle of the iris, contributing to pupil dilation. Together, these agents produce rapid and effective dilation of the pupil, facilitating detailed eye examinations and procedures. ⚠️ Side Effects Common side effects may include: • Eye pain or stinging • Blurred vision • Sensitivity to light (photophobia) • Allergic reactions These effects are typically temporary and resolve shortly after the examination. 🧪 Safety and Precautions • Driving and Operating Machinery: Avoid activities that require clear vision, such as driving, immediately after application, as the solution can cause temporary blurred vision. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or while breastfeeding, as safety data may be limited. • Drug Interactions: Be cautious when using Tropind Plus with certain medications, especially monoamine oxidase inhibitors (MAOIs) or tricyclic antidepressants, as interactions may occur.

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Eye Care

Blink Plus (Polyethylene & Propylene Glycol) Ophthalmic Solution is an over-the-counter eye drop formulation designed to provide relief for dry or irritated eyes. Here's an overview of its uses, dosage, side effects, and safety considerations: ________________________________________ 🔍 Uses Blink Plus combines two lubricating agents: • Polyethylene Glycol 400 (0.4%): Acts as a lubricant to relieve dryness and irritation by providing moisture to the eyes. It creates a protective layer on the eye's surface, reducing discomfort and enhancing tear film stability. Propylene Glycol (0.3%): Functions as a solvent and humectant, helping to dissolve and stabilize the active ingredients while attracting moisture to the eye, aiding in hydration and alleviating dryness. This combination is used to treat dry eye symptoms caused by environmental factors such as wind, sun, air conditioning, or prolonged screen time. ________________________________________ 💧 Dosage and Administration • General Dosage: Instill one or two drops into the affected eye(s) as needed. • Application Method: 1. Wash your hands thoroughly before use. 2. Tilt your head back slightly and pull down the lower eyelid to form a pouch. 3. Hold the dropper above the eye and instill the prescribed number of drops. 4. Close the eye gently and apply gentle pressure to the inner corner of the eye for 1 to 2 minutes to prevent the medication from draining away. 5. Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. ________________________________________ ⚠️ Safety and Side Effects • Common Side Effects: o Temporary blurred vision. o Mild burning or stinging sensation upon application. o Eye discomfort or irritation. • Redness or watering of the eyes. • Serious Side Effects: o Persistent eye pain or swelling. o Allergic reactions such as rash, itching, swelling, or severe dizziness. • Precautions: o Consult your doctor if you are pregnant or breastfeeding, as the safety of Blink Plus during these periods is not well-established. o Use with caution if you have a history of eye infections or other eye conditions. o Avoid driving or operating machinery if you experience blurred vision or visual disturbances.

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General Medicine

Labecanol Injection 4 ml belongs to the group of anti-hypertensive medicines called beta-blocking agents used to treat severe hypertension (high blood pressure). Additionally, American Labecanol Injection 4 ml is used to control high blood pressure in pregnancy and during anaesthesia. Labecanol Injection 4 ml contains ‘labetalol’ that works by blocking the receptors in the cardiovascular (circulatory) system, this helps in decreasing the blood pressure in the blood vessels. Thus, it helps lower the blood pressure to normal. In some cases, American Labecanol Injection 4 ml may cause common side effects such as postural hypotension, dizziness, fatigue, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

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Kidney Disease Medicine

Zyrop 5000IU injection contains active components such as Recombinant human erythropoietin alfa/epoetin alfa. It is a medication that belongs to a class of drugs called erythropoiesis-stimulating agents (ESAs). This medication treats anemia caused by chronic kidney disease (CKD), cancer chemotherapy, or HIV infection treatment with zidovudine. It also reduces the need for red blood cell transfusions in patients at high risk for blood loss due to planned surgery or other procedures. Zyrop 5000IU injection should not be used in patients with hypersensitivity to it or any of its components, uncontrolled hypertension, active thrombotic microangiopathy (TMA), pure red cell aplasia (PRCA), uncontrolled seizures, pregnancy, or lactation. It should also be used cautiously in patients with a history of blood clots, heart disease, stroke, kidney disease, liver disease, thalassemia, sickle cell anemia, myelodysplastic syndrome, leukemia, or cancer. It should only be used in children under 18 if the benefits outweigh the risks. Older adults taking this medication should be closely monitored for side effects. Before starting this medication, it is important to talk to your doctor about the risks and benefits of Zyrop 5000IU injection.

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Kidney Disease Medicine

Nodosis Suspension 300 ml belongs to a group of medicines called alkalinising agents used to correct the acid-alkaline balance in the body. Nodosis Suspension 300 ml is used to treat acid indigestion, heartburn, sour stomach, stomach upset, metabolic acidosis, severe diarrhoea and poisoning. Nodosis Suspension 300 ml may also be used to treat patients who have taken too many tricyclic antidepressants only after other resuscitation methods have been attempted. Nodosis Suspension 300 ml contains ‘Sodium bicarbonate’, which helps in neutralising the acidic pH in the stomach. Thereby, Nodosis Suspension 300 ml helps to provide relief from acidity. Nodosis Suspension 300 ml helps in reducing the amount of acid in the body after a heart attack in patients who have too much potassium in their blood or too much acid in their body. Nodosis Suspension 300 ml can also be prescribed to make the blood or urine less acidic in certain conditions. Take Nodosis Suspension 300 ml as prescribed. You are advised to take Nodosis Suspension 300 ml for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as dry mouth, urinating more than usual, and increased thirst. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

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Heart Disorder

Celginase 10000 Injection belongs to the class of medicines called antineoplastic (anticancer) agents used in the treatment of acute lymphoblastic leukaemia (a type of blood and bone marrow cancer). Acute lymphoblastic leukaemia (ALL) is the most common childhood cancer. It is a type of blood cancer which causes excessive production of lymphocytes (a type of white blood cells) by the bone marrow. Celginase 10000 Injection contains L Asparaginase which works by lowering asparagine levels in the body, which is necessary for the survival of cancer cells. Thus, Celginase 10000 Injection stops the cancer cells from dividing and growing. Celginase 10000 Injection will be administered by a healthcare professional; do not self-administer. Sometimes, Celginase 10000 Injection may cause common side effects such as nausea, weight loss, generalised pain or muscle pain, infections or a decrease in normal blood content. Most of these side effects of Celginase 10000 Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. If you are allergic to L asparaginase or other medicines, please tell your doctor. You are recommended to avoid breastfeeding during treatment with Celginase 10000 Injection as there may be a risk to the feeding child. If you are pregnant or planning pregnancy, please inform your doctor before receiving Celginase 10000 Injection. Also, you are recommended to use effective contraceptive methods before and for at least 3 months after treatment with Celginase 10000 Injection to prevent pregnancy. Celginase 10000 Injection is given to children in doses as advised by the doctor, depending on the age. Avoid driving after receiving Celginase 10000 Injection as it may cause drowsiness or dizziness.

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Hepatitis Medicine

Heparel 100IU injection contains the active ingredient called human hepatitis B immunoglobulin, which belongs to the family of antiviral agents. It is used in adults and children to protect from the hepatitis B virus, usually given with the hepatitis B vaccine. The Hepatitis B virus damages the liver and gradually stops the liver from working properly. Additionally, this medicine can also be given to newborn babies born to mothers with the hepatitis B virus. Do not take this drug if you are allergic to hepatitis B Immunoglobulin and its other ingredients. Usually, this vaccine is given if you have been exposed to infections or if your previous hepatitis B vaccination has not worked. It is also given if you are having kidney dialysis (waiting for a hepatitis B vaccination to be fully effective). Before taking the Heparel 100IU injection, inform your doctor if you have any allergic reaction or a blood disorder (blood clotting). Notify your doctor if you have IgA deficiency, high blood pressure, or diabetics, recently had any vaccinations, or planning to get any vaccination, especially MMR (measles, mumps, and rubella) vaccine and Varicella (chickenpox) vaccine. Consult your doctor for more information about Heparel 100IU injection.

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