Colistican 3 Injection is an intravenous formulation containing Colistimethate Sodium 3 Million IU, manufactured by American Remedies. It is primarily used to treat severe infections caused by multidrug-resistant Gram-negative bacteria. ________________________________________ 🩺 Uses of Colistican 3 Injection Colistican 3 Injection is indicated for: • Ventilator-Associated Pneumonia (VAP): A lung infection acquired during mechanical ventilation. • Bloodstream Infections (Sepsis): Infections caused by resistant bacteria entering the bloodstream. • Urinary Tract Infections (UTIs): Caused by multidrug-resistant Gram-negative organisms. • Intra-abdominal Infections: Such as peritonitis. • Cystic Fibrosis: For chronic pulmonary infections due to Pseudomonas aeruginosa in both adults and children. ________________________________________ 💊 Mechanism of Action Colistimethate sodium is a prodrug that, upon administration, is converted to colistin. Colistin binds to the bacterial cell membrane, disrupting its structure and leading to cell death. It is particularly effective against aerobic Gram-negative bacteria with hydrophobic outer membranes. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Renal Function: Use with caution in patients with kidney impairment. • Neurological Effects: Monitor for signs of neurotoxicity, including dizziness and muscle weakness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Injection site reactions • Renal toxicity • Neurological symptoms (e.g., confusion, dizziness) • Gastrointestinal disturbances (e.g., nausea, vomiting) • Muscle weakness

Colistican 2 Injection is a brand of Colistimethate Sodium for Injection, manufactured by American Remedies. It is a polymyxin-class antibiotic used to treat serious infections caused by multidrug-resistant Gram-negative bacteria. ________________________________________ 🩺 Uses of Colistican 2 Injection Colistican 2 Injection is primarily indicated for: • Ventilator-Associated Pneumonia (VAP): A lung infection acquired during mechanical ventilation. • Bacteremia (Bloodstream Infection): Infections caused by resistant bacteria entering the bloodstream. • Lower Respiratory Tract Infections: Including severe cases of pneumonia and bronchitis. • Urinary Tract Infections (UTIs): Caused by multidrug-resistant Gram-negative organisms. These infections are typically caused by pathogens such as Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae, which are resistant to multiple antibiotics. ________________________________________ 💊 Mechanism of Action Colistimethate sodium is a prodrug that, upon administration, is converted to colistin. Colistin binds to the bacterial cell membrane, disrupting its structure and leading to cell death. It is particularly effective against aerobic Gram-negative bacteria with hydrophobic outer membranes. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Renal Function: Use with caution in patients with kidney impairment. • Neurological Effects: Monitor for signs of neurotoxicity, including dizziness and muscle weakness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Injection site reactions • Renal toxicity • Neurological symptoms (e.g., confusion, dizziness) • Gastrointestinal disturbances (e.g., nausea, vomiting) • Muscle weakness

Colistican 1 Injection is a brand of Colistimethate Sodium for Injection manufactured by American Remedies. Colistimethate sodium is a polymyxin-class antibiotic, also known as polymyxin E, used to treat serious infections caused by multidrug-resistant Gram-negative bacteria. ________________________________________ 🩺 Uses of Colistican 1 Injection Colistican 1 Injection is primarily used for: • Multidrug-Resistant Infections: Especially those caused by Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae. • Ventilator-Associated Pneumonia (VAP): A lung infection acquired during mechanical ventilation. • Urinary Tract Infections (UTIs): Caused by resistant Gram-negative bacteria. • Bloodstream Infections (Sepsis): Resulting from resistant pathogens. • Intra-abdominal Infections: Such as peritonitis. • Cystic Fibrosis: For chronic pulmonary infections due to Pseudomonas aeruginosa in both adults and children. ________________________________________ 💊 Mechanism of Action Colistimethate sodium is a prodrug that, upon administration, is converted to colistin. Colistin binds to the bacterial cell membrane, disrupting its structure and leading to cell death. It is particularly effective against aerobic Gram-negative bacteria with hydrophobic outer membranes. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Renal Function: Use with caution in patients with kidney impairment. • Neurological Effects: Monitor for signs of neurotoxicity, including dizziness and muscle weakness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Injection site reactions • Renal toxicity • Neurological symptoms (e.g., confusion, dizziness) • Gastrointestinal disturbances (e.g., nausea, vomiting) • Muscle weakness

Uti-Zen® is a palatable food supplement for Animals prone to urinary discomfort (elderly, stressed animals…). Its breakable tablets enable a great ease of use. Successfully used in human medicine for centuries, the cranberry now offers its benefits to pets. Cranberry is known for its properties in limiting the adhesion of E. Coli bacteria and also for its antioxidant effect. Uti-Zen® is very easy to use thanks to its breakable and palatable tablet presentation which facilitates spontaneous intake.

Pipracan 4.5 Injection is a combination antibiotic medication containing Piperacillin (4 g) and Tazobactam (0.5 g). This formulation is used to treat a wide range of serious bacterial infections that may not respond to other antibiotics. ________________________________________ 🔹 Common Uses Pipracan 4.5 Injection is prescribed for: • Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) • Urinary tract infections (UTIs) • Intra-abdominal infections (e.g., peritonitis) • Skin and soft tissue infections, including diabetic foot infections • Gynecological infections, such as uterine infections • Bone and joint infections • Bloodstream infections (bacteremia) It is also used for prophylactic treatment in surgical procedures to prevent infections. ________________________________________ 🔹 How It Works • Piperacillin is a broad-spectrum penicillin antibiotic that inhibits bacterial cell wall synthesis, leading to bacterial cell death. • Tazobactam is a beta-lactamase inhibitor that protects piperacillin from degradation by beta-lactamase enzymes produced by certain bacteria, thereby enhancing its efficacy. This combination allows Pipracan 4.5 to target a wide array of bacteria, including those resistant to other antibiotics. ________________________________________ 🔹 Administration Pipracan 4.5 Injection is administered intravenously by a healthcare professional. The dosage and duration of treatment depend on the type and severity of the infection, as well as the patient's medical condition. Self-administration is not recommended. ________________________________________ 🔹 Side Effects Common side effects may include: • Nausea or vomiting • Diarrhea • Rash or itching • Pain, redness, or swelling at the injection site Serious side effects are rare but can include allergic reactions, liver enzyme abnormalities, or blood disorders. Seek immediate medical attention if you experience symptoms like difficulty breathing, swelling of the face or throat, or unusual bruising or bleeding. ________________________________________ 🔹 Precautions Before using Pipracan 4.5 Injection, inform your doctor if you have: Allergies to penicillins or beta-lactam antibiotics • Kidney or liver disease • A history of gastrointestinal diseases, such as colitis • Bleeding disorders • Undergoing dialysisUse during pregnancy and breastfeeding should be discussed with your healthcare provider. The medication should only be used if the potential benefits justify the potential risks.

Xylistin 1MIU Injection is an antibiotic that fights bacteria. It is used to treat severe bacterial infections of the body. It is commonly used for critically ill patients admitted to the hospital. Xylistin 1MIU Injection is given under the supervision of a healthcare professional. You should not self-administer this medicine at home. The dose and duration will be decided by your doctor based on the severity and type of infection you have. Get the injection regularly for as long as your doctor has prescribed to get maximum benefits. Common side effects of this medicine include gastrointestinal upset, slurred speech, dizziness, vertigo, fever, rash, and paresthesia. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or do not go away.

Xylistin Forte 2MIU Injection is an antibiotic that fights bacteria. It is used to treat severe bacterial infections of the body. It is commonly used for critically ill patients admitted to the hospital. Xylistin Forte 2MIU Injection is given under the supervision of a healthcare professional. You should not self-administer this medicine at home. The dose and duration will be decided by your doctor based on the severity and type of infection you have. Get the injection regularly for as long as your doctor has prescribed to get maximum benefits. Common side effects of this medicine include gastrointestinal upset, slurred speech, dizziness, vertigo, fever, rash, and paresthesia. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or do not go away.

Xylistin Forte Plus 3MIU Injection is an antibiotic that fights bacteria. It is used to treat severe infections of the lungs, stomach, urinary tract, blood, and others. It works by killing the bacteria that cause these problems. It is commonly used to treat critically ill patients admitted to the hospital. Xylistin Forte Plus 3MIU Injection is given under the supervision of a healthcare professional. You should not self-administer this medicine at home. The dose and duration will be decided by your doctor based on the severity and type of infection you have. Get the injection regularly for as long as your doctor has prescribed to get maximum benefits. It may cause pain, swelling, or redness at the site of injection. However, these are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or do not go away. It can even cause kidney damage in some people. You might need to be monitored while on this medication.

Xylistin 4.5MIU Injection is an antibiotic that fights bacteria. It is used to treat severe bacterial infections of the body. It is commonly used for critically ill patients admitted to the hospital. Xylistin 4.5MIU Injection is given under the supervision of a healthcare professional. You should not self-administer this medicine at home. The dose and duration will be decided by your doctor based on the severity and type of infection you have. Get the injection regularly for as long as your doctor has prescribed to get maximum benefits. Common side effects of this medicine include gastrointestinal upset, slurred speech, dizziness, vertigo, fever, rash, and paresthesia. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or do not go away.