BRILINTA 90MG TABLET 180'S ASTRAZENECA PHARMA INDIA LTD Salt: Ticagrelor (90mg) Description Brilinta 90mg Tablet belongs to a group of medicines called antiplatelet or blood thinners. It reduces the formation of harmful blood clots in blood vessels. This helps to prevent a heart attack or stroke in people with heart disease. Brilinta 90mg Tablet belongs to a group of medicines called antiplatelet or blood thinners. It reduces the formation of harmful blood clots in blood vessels. This helps to prevent a heart attack or stroke in people with heart disease. Benefits In Prevention of heart attack and stroke Brilinta 90mg Tablet is an antiplatelet medicine or blood thinner. It prevents blood from clotting inside the veins and arteries. This helps the blood flow freely around your body thereby preventing a heart attack or stroke (or deep vein thrombosis or pulmonary embolism). Take this medicine regularly and make appropriate lifestyle changes to achieve maximum benefits. It is often prescribed along with a low dose of aspirin which also helps to prevent blood from clotting. Side Effects Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Brilinta Bleeding Breathlessness

Brilinta 90mg Tablet Marketer AstraZeneca SALT COMPOSITION Ticagrelor (90mg) Storage Store below 30°C Uses of Brilinta Tablet Heart attack Prevention of heart attack and stroke Unstable angina Product introduction Brilinta 90mg Tablet belongs to a group of medicines called antiplatelet or blood thinners. It reduces the formation of harmful blood clots in blood vessels, which helps to prevent heart attacks or strokes in people with heart disease. Brilinta 90mg Tablet is also used to treat people with a recent heart attack or severe heart-related chest pain (unstable angina) who have undergone stenting of the heart. It helps to prevent serious heart-related problems like having another heart attack, stroke, or formation of blood clots in stents in such people. Your doctor will also prescribe aspirin, another antiplatelet medicine, along with this medicine. Brilinta 90mg Tablet may be taken with or without food and should be taken regularly at the same time each day. It is important to keep taking it even if you feel well. If you stop taking this medicine, it may increase your chances of having another heart attack or stroke. The most common side effects of this medicine are dyspnea (breathlessness) and bleeding. If you cut or injure yourself, it may take longer than usual for the bleeding to stop. Such episodes of bleeding are usually mild and resolve on their own. Mild breathlessness caused by this medicine usually resolves on its own with continued treatment. Let your doctor know if bleeding persists or if the breathlessness worsens or does not go away. Brilinta 90mg Tablet is not suitable for some people. Do not take it if you are bleeding from anywhere in the body, such as a stomach ulcer or bleeding within the brain. It is also not recommended for people with liver diseases. Before using the medicine, inform your doctor of any such problems. Benefits of Brilinta Tablet In Prevention of heart attack and stroke Brilinta 90mg Tablet is an antiplatelet medicine or blood thinner. It prevents blood from clotting inside the veins and arteries, helping the blood flow freely around your body and preventing a heart attack or stroke (deep vein thrombosis or pulmonary embolism). To achieve maximum benefits, take this medicine regularly and make appropriate lifestyle changes. It is often prescribed with a low dose of aspirin, which also helps prevent blood from clotting. Side effects of Brilinta Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Brilinta Bleeding Breathlessness How to use Brilinta Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Brilinta 90mg Tablet may be taken with or without food, but it is better to take it at a fixed time. How Brilinta Tablet works Brilinta 90mg Tablet is an antiplatelet medication. It works by preventing platelets from sticking together, thereby decreasing the formation of harmful blood clots. This lowers the chance of heart attack or stroke. Safety advice warnings Alcohol CAUTION Caution is advised when consuming alcohol with Brilinta 90mg Tablet. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Brilinta 90mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. warnings Breast feeding CONSULT YOUR DOCTOR Information regarding the use of Brilinta 90mg Tablet during breastfeeding is not available. Please consult your doctor. warnings Driving CONSULT YOUR DOCTOR It is not known whether Brilinta 90mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Dizziness, confusion, vertigo, and syncope have been reported in some patients. If you experience such symptoms, be cautious while driving or using machines. warnings Kidney SAFE IF PRESCRIBED Brilinta 90mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Brilinta 90mg Tablet is recommended. Limited information is available on the use of Brilinta 90mg Tablet in renal dialysis patients. warnings Liver SAFE IF PRESCRIBED Brilinta 90mg Tablet is safe to use in patients with liver disease. No dose adjustment of Brilinta 90mg Tablet is recommended. Use of Brilinta 90mg Tablet is not recommended in patients with severe liver disease.

INTRODUCTION ABOUT RITUXIREL 100 INJECTION RITUXIREL 100 INJECTION contains Rituximab which belongs to the group of medicines called Anticancer drugs. It is used to manage blood cancer (leukaemia) and lymph cancer (lymphoma). It can also be used to manage various auto-immune disease conditions such as rheumatoid arthritis, granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels) and pemphigus vulgaris (severe skin blistering and peeling especially on the mouth, nose, throat, eyes and genitals). It is mostly used in combination with other cytotoxic anticancer agents to achieve better results. It is suitable for use both in adults and in children (aged 6 months or older). RITUXIREL 100 INJECTION will be administered to you only by an oncologist or a trained professional into your vein (as intravenous infusion). Before receiving RITUXIREL 100 INJECTION inform your doctor if you have any heart problems (such as chest pain, heart attack, heart failure or abnormal heartbeat). You must also inform your doctor if you currently have or previously had hepatitis B infection or any other mild infections (including minor cough and cold) as a precaution. RITUXIREL 100 INJECTION is not recommended for use in pregnant or breastfeeding women. Both men and women receiving RITUXIREL 100 INJECTION must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with RITUXIREL 100 INJECTION. The most common side effects of receiving this medicine are fever, chills, skin rashes with itching, shortness of breath and low blood pressure. Consult your doctor if any of these side effect worsens. USES OF RITUXIREL 100 INJECTION It is used to manage: Blood cancer (Chronic lymphocytic leukaemia) Lymph cancer (Non-Hodgkin’s Lymphoma) Rheumatoid arthritis (joint pain and inflammation) Granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels) Pemphigus vulgaris (severe skin blistering and peeling especially on the mouth, nose, throat, eyes and genitals) HOW RITUXIREL 100 INJECTION WORKS RITUXIREL 100 INJECTION is a monoclonal antibody. It destroys the immune cells (B-cells) that triggers cancer formation. It also reduces the production of certain chemicals within the body (such as rheumatoid factor, T-cells, cytokines) that causes inflammation, pain and swelling which helps in managing various autoimmune diseases. DIRECTIONS FOR USE RITUXIREL 100 INJECTION will be given to you only by a doctor or a nurse into the vein (intravenously). Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF RITUXIREL 100 INJECTION COMMON increased infections (bacterial, viral or fungal) low RBC, WBC and platelet counts in blood nausea, vomiting, diarrhea, stomach pain, constipation, indigestion mouth ulcers hair loss fever, chills, pneumonia, shingles, cold, sinusitis thrush, urinary tract infection headache, dizziness, tiredness, weakness hepatitis B infection high blood sugar and cholesterol levels weight loss, lack of appetite numbness, tingling, pricking, burning sensation on the skin restlessness, problems in falling asleep, anxiety, depression flushing (skin redness) eye inflammation or watery eyes ringing sound in the ears, ear pain uneven or fast heart rate, high or low blood pressure shortness of breath, runny nose, nasal itching and repeated sneezing increased sweating, night sweats muscle pain, joint pain, back pain, neck pain pain while passing urine fungal foot infection (athlete’s foot) tremors (shakiness) swelling of the hands or ankles UNCOMMON blood clotting problems changes in taste slow heart rate chest tightness and lung problems RARE Contact your doctor immediately if you experience any of the following side effects: fever, chills, shivering, nausea, vomiting, skin rashes with blisters and itching, flushing, pain at the infusion site, headache, tiredness, wheezing, high blood pressure, palpitations, swelling of throat or tongue, runny or itchy nose and chest pain fever, cough, sore throat, burning pain while passing urine, feeling weak or generally unwell signs of brain problem (such as memory loss, trouble thinking, difficulty in walking or vision problems) signs of severe skin reactions (such as severe skin blistering and redness that may appear on the on the mucous membranes, such as inside the mouth, the genital areas or the eyelids, with fever)

INTRODUCTION ABOUT RITUXIREL 500MG INJECTION RITUXIREL 500MG INJECTION contains Rituximab which belongs to the group of medicines called Anticancer drugs. It is used to manage blood cancer (leukaemia) and lymph cancer (lymphoma). It can also be used to manage various auto-immune disease conditions such as rheumatoid arthritis, granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels) and pemphigus vulgaris (severe skin blistering and peeling especially on the mouth, nose, throat, eyes and genitals). It is mostly used in combination with other cytotoxic anticancer agents to achieve better results. It is suitable for use both in adults and in children (aged 6 months or older). RITUXIREL 500MG INJECTION will be administered to you only by an oncologist or a trained professional into your vein (as intravenous infusion). Before receiving RITUXIREL 500MG INJECTION inform your doctor if you have any heart problems (such as chest pain, heart attack, heart failure or abnormal heartbeat). You must also inform your doctor if you currently have or previously had hepatitis B infection or any other mild infections (including minor cough and cold) as a precaution. RITUXIREL 500MG INJECTION is not recommended for use in pregnant or breastfeeding women. Both men and women receiving RITUXIREL 500MG INJECTION must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with RITUXIREL 500MG INJECTION. The most common side effects of receiving this medicine are fever, chills, skin rashes with itching, shortness of breath and low blood pressure. Consult your doctor if any of these side effect worsens. USES OF RITUXIREL 500MG INJECTION It is used to manage: Blood cancer (Chronic lymphocytic leukaemia) Lymph cancer (Non-Hodgkin’s Lymphoma) Rheumatoid arthritis (joint pain and inflammation) Granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels) Pemphigus vulgaris (severe skin blistering and peeling especially on the mouth, nose, throat, eyes and genitals) HOW RITUXIREL 500MG INJECTION WORKS RITUXIREL 500MG INJECTION is a monoclonal antibody. It destroys the immune cells (B-cells) that triggers cancer formation. It also reduces the production of certain chemicals within the body (such as rheumatoid factor, T-cells, cytokines) that causes inflammation, pain and swelling which helps in managing various autoimmune diseases. DIRECTIONS FOR USE RITUXIREL 500MG INJECTION will be given to you only by a doctor or a nurse into the vein (intravenously). Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF RITUXIREL 500MG INJECTION COMMON increased infections (bacterial, viral or fungal) low RBC, WBC and platelet counts in blood nausea, vomiting, diarrhea, stomach pain, constipation, indigestion mouth ulcers hair loss fever, chills, pneumonia, shingles, cold, sinusitis thrush, urinary tract infection headache, dizziness, tiredness, weakness hepatitis B infection high blood sugar and cholesterol levels weight loss, lack of appetite numbness, tingling, pricking, burning sensation on the skin restlessness, problems in falling asleep, anxiety, depression flushing (skin redness) eye inflammation or watery eyes ringing sound in the ears, ear pain uneven or fast heart rate, high or low blood pressure shortness of breath, runny nose, nasal itching and repeated sneezing increased sweating, night sweats muscle pain, joint pain, back pain, neck pain pain while passing urine fungal foot infection (athlete’s foot) tremors (shakiness) swelling of the hands or ankles UNCOMMON blood clotting problems changes in taste slow heart rate chest tightness and lung problems RARE Contact your doctor immediately if you experience any of the following side effects: fever, chills, shivering, nausea, vomiting, skin rashes with blisters and itching, flushing, pain at the infusion site, headache, tiredness, wheezing, high blood pressure, palpitations, swelling of throat or tongue, runny or itchy nose and chest pain fever, cough, sore throat, burning pain while passing urine, feeling weak or generally unwell signs of brain problem (such as memory loss, trouble thinking, difficulty in walking or vision problems) signs of severe skin reactions (such as severe skin blistering and redness that may appear on the on the mucous membranes, such as inside the mouth, the genital areas or the eyelids, with fever) HOW TO MANAGE SIDE EFFECTS Constipation Try to eat more high-fibre foods such as fresh fruit, vegetables, cereals, and drink plenty of water. Try doing exercise regularly (going for a daily walk or run). If this does not help, inform your doctor for receiving alternate managements for constipation.

A healthy eye produces enough tears to keep it moist and healthy. However, in patients with Dry Eyes or Keratoconjunctivitis sicca (KCS), either the amount of tear production is reduced or the rate at which the tear evaporates is increased. Visioaid is Schirmer’s test strip (STT) that helps to diagnose KCS. Based on the extent to which the STT strip is moistened by tears, the veterinarian is able to diagnose the severity of KCS and provide suitable treatment. The veterinarian will place the tip of VISIOAID inside the eyelid, closes the eye, and holds the paper for exactly 60 seconds. The distance travelled by the tears on the VISIOAID strip in sixty seconds is recorded and the diagnosis is made.

Tropind (Tropicamide 1%) Ophthalmic Solution is commonly used for the following purposes: Pupillary Dilation (Mydriasis): Tropind is often used by eye care professionals to dilate the pupils during eye exams, such as fundoscopy or slit-lamp examinations. It helps them get a clear view of the retina, optic nerve, and other structures inside the eye. Cycloplegia: Tropind is used to temporarily paralyze the ciliary muscle in the eye, which controls the lens's focusing ability. This is useful during certain types of eye exams, such as refraction tests, to evaluate the eye's refractive error without interference from accommodation (focusing). Treatment of Certain Eye Conditions: It may also be used to treat or manage certain eye conditions, such as uveitis (inflammation of the middle layer of the eye), to relieve pain and prevent further spasms of the eye muscles. How it works: Tropind contains tropicamide, which is an anticholinergic agent that works by blocking the action of acetylcholine on the muscles of the iris (pupil) and the ciliary body, causing pupil dilation and paralysis of accommodation. Administration: It is usually instilled directly into the eye as drops. The effects typically last for a few hours, depending on the individual and the purpose of use. Side effects: Potential side effects may include temporary blurry vision, sensitivity to light (due to pupil dilation), or stinging when the drops are first applied. Always follow the instructions provided by your healthcare provider or the product label when using Tropind.

Timipar (Timolol Maleate 0.25%) eye drops are a prescription medication primarily used to manage elevated intraocular pressure (IOP) associated with conditions like open-angle glaucoma and ocular hypertension. By reducing the production of aqueous humor, the fluid inside the eye, Timolol helps lower IOP, thereby reducing the risk of optic nerve damage and potential vision loss . ________________________________________ ✅ Primary Uses • Open-Angle Glaucoma: A common type of glaucoma where the drainage angle in the eye remains open, but the trabecular meshwork is partially blocked, leading to increased IOP. • Ocular Hypertension: A condition characterized by higher-than-normal IOP without any signs of glaucoma damage. ________________________________________ 💊 Dosage and Administration • Typical Dosage: Instill one drop of the 0.25% solution into the affected eye(s) once or twice daily, as directed by your healthcare provider. • Application Tips: o Wash your hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them . ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: o Hypersensitivity to any component of the formulation. o Bronchial asthma or a history of bronchial asthma. o Severe chronic obstructive pulmonary disease (COPD). • Sinus bradycardia, second- or third-degree atrioventricular block, overt cardiac failure, or cardiogenic shock . • Cautions: o Use with caution in patients with a history of heart disease, diabetes, or thyroid disorders, as beta-blockers can mask symptoms of hypoglycemia and hyperthyroidism. o Monitor for potential additive effects when used with other systemic beta-blockers . ________________________________________ 🧪 Mechanism of Action Timolol is a non-selective beta-adrenergic antagonist (beta-blocker) that reduces aqueous humor production in the eye, leading to a decrease in IOP. Its onset of action is typically within 20 minutes, with effects lasting up to 24 hours .

Ofx Eye/Ear Drops is an antibiotic, used in the treatment of bacterial eye/ear infections. It relieves the symptoms of the infection by stopping the further growth of the causative microorganisms. Ofx Eye/Ear Drops is for external use only. Take it in the dose and duration as advised by your doctor. Hold the dropper close to the eye/ear without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid or ear. Wipe off extra liquid. Avoid skipping any doses and finish the full course of treatment even if you feel better. It may cause application site irritation and burning sensation immediately following application. However, these side effects are temporary and usually subside on their own. Inform your doctor if they persist for a longer duration. While using for eye infections, it may cause short term blurring of vision when first used. Use caution before driving or using machines. Do not wear contact lenses while using it.

Ofx-P Eye/Ear Drops is an antibiotic, used in the treatment of bacterial eye/ear infections. It relieves the symptoms of the infection by stopping the further growth of the causative microorganisms. Ofx-P Eye/Ear Drops is for external use only. Take it in the dose and duration as advised by your doctor. Hold the dropper close to the eye/ear without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid or ear. Wipe off extra liquid. Avoid skipping any doses and finish the full course of treatment even if you feel better. It may cause application site irritation and burning sensation immediately following application. However, these side effects are temporary and usually subside on their own. Inform your doctor if they persist for a longer duration. While using for eye infections, it may cause short term blurring of vision when first used. Use caution before driving or using machines. Do not wear contact lenses while using it.