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General Medicine

Restome Tablet is a dietary supplement formulated to support restful sleep and overall well-being. Manufactured by Liv Bio Pharma, it combines natural ingredients known for their calming and rejuvenating properties. ________________________________________ 🛏️ Composition Each vegetarian capsule contains: • Melatonin – 5 mg • Shoden™ Bio-Active Ashwagandha Extract – 60 mg • Ashwagandha Extract – 435 mg Melatonin is a hormone that regulates the sleep-wake cycle, while Ashwagandha is an adaptogen that helps the body manage stress and promotes relaxation. ________________________________________ 🌿 Uses and Benefits Restome Tablet is primarily used to: • Promote Restful Sleep: Helps in cases of insomnia, jet lag, and delayed sleep-wake phase disorder. • Reduce Sleep Onset Time: Facilitates falling asleep faster. • Improve Sleep Quality: Enhances sleep maintenance and reduces frequent awakenings. • Alleviate Anxiety: Ashwagandha's adaptogenic properties help reduce stress and anxiety levels. • Support Overall Well-being: Contributes to rejuvenation and freshness. ________________________________________ ⚠️ Side Effects Restome Tablet is generally well-tolerated. However, some individuals may experience mild side effects, including: • Drowsiness • Headache • Nausea • Gastrointestinal discomfort If any side effects persist or worsen, it's advisable to consult a healthcare professional. ________________________________________ 💊 Dosage and Administration • Recommended Dosage: One capsule per day, preferably taken 30 minutes before bedtime. • Administration: Swallow the capsule whole with a glass of water. • Consistency: For best results, use consistently as directed. ________________________________________ 🛒 Availability and Pricing Restome Tablet is available for purchase online and in select pharmacies across India. The price may vary depending on the retailer. ________________________________________ ⚠️ Precautions • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. • Medical Conditions: Individuals with autoimmune diseases or thyroid disorders should seek medical advice before use. • Drug Interactions: Inform your doctor about all medications you are currently taking to avoid potential interactions.

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General Medicine

Nezolid 600 Injection is a brand of Linezolid Injection 600 mg/300 mL, manufactured by American Remedies. Linezolid is an antibiotic belonging to the oxazolidinone class, effective against various serious bacterial infections. ________________________________________ ✅ Primary Uses Nezolid 600 Injection is indicated for the treatment of: • Nosocomial Pneumonia: Hospital-acquired pneumonia caused by susceptible strains of bacteria. • Community-Acquired Pneumonia (CAP): Pneumonia acquired outside of healthcare settings. • Complicated Skin and Skin Structure Infections (cSSSIs): Infections involving deeper layers of the skin and underlying tissues. • Vancomycin-Resistant Enterococcus faecium (VRE) Infections: Including cases with concurrent bacteremia. These infections are typically caused by Gram-positive bacteria, including multidrug-resistant strains. ________________________________________ ⚙️ Mechanism of Action Linezolid works by inhibiting bacterial protein synthesis. It binds to the bacterial ribosome, preventing the formation of the initiation complex necessary for protein production, thereby halting bacterial growth. This bacteriostatic action is particularly effective against Gram-positive organisms. ________________________________________ ⚠️ Precautions • Drug Interactions: Avoid concurrent use with monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants (TCAs), and certain other medications due to the risk of serotonin syndrome. • Pre-existing Conditions: Use with caution in patients with a history of seizures, diabetes mellitus, liver cirrhosis, or renal impairment. • Dietary Restrictions: Limit intake of foods high in tyramine (e.g., aged cheeses, cured meats, soy products) to reduce the risk of hypertensive reactions. • Pregnancy and Lactation: Consult a healthcare provider before use during pregnancy or breastfeeding.

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General Medicine

Mucanix Injection is a brand of Acetylcysteine Injection, manufactured by American Remedies. Acetylcysteine is a mucolytic agent that helps in thinning and loosening mucus in the airways, making it easier to cough up and clear the airways. ________________________________________ ✅ Primary Uses Mucanix Injection is primarily used for: • Respiratory Disorders: Conditions such as chronic bronchitis, asthma, and cystic fibrosis, where there is excessive mucus production. • Paracetamol (Acetaminophen) Overdose: As an antidote to prevent liver damage when administered within 8 hours of overdose. ________________________________________ ⚙️ Mechanism of Action Acetylcysteine works by: • Breaking down mucus: It reduces the viscosity of mucus, facilitating easier expectoration. • Restoring glutathione levels: In cases of paracetamol overdose, it replenishes glutathione, a vital antioxidant, aiding in detoxification and protecting the liver. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Allergy: Do not use if allergic to acetylcysteine or any of its components. • Asthma: Use with caution in patients with asthma; monitoring is required. • Pregnancy and Breastfeeding: Consult a doctor before use during pregnancy or breastfeeding. Common Side Effects: • Nausea • Vomiting • Rash • Fever • Headache Serious Side Effects: • Anaphylactic reactions (rare) • Hypotension • Tachycardia If you experience any of these serious side effects, seek immediate medical attention.

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Antibiotic Medicine

Colistican 2 Injection is a brand of Colistimethate Sodium for Injection, manufactured by American Remedies. It is a polymyxin-class antibiotic used to treat serious infections caused by multidrug-resistant Gram-negative bacteria. ________________________________________ 🩺 Uses of Colistican 2 Injection Colistican 2 Injection is primarily indicated for: • Ventilator-Associated Pneumonia (VAP): A lung infection acquired during mechanical ventilation. • Bacteremia (Bloodstream Infection): Infections caused by resistant bacteria entering the bloodstream. • Lower Respiratory Tract Infections: Including severe cases of pneumonia and bronchitis. • Urinary Tract Infections (UTIs): Caused by multidrug-resistant Gram-negative organisms. These infections are typically caused by pathogens such as Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae, which are resistant to multiple antibiotics. ________________________________________ 💊 Mechanism of Action Colistimethate sodium is a prodrug that, upon administration, is converted to colistin. Colistin binds to the bacterial cell membrane, disrupting its structure and leading to cell death. It is particularly effective against aerobic Gram-negative bacteria with hydrophobic outer membranes. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Renal Function: Use with caution in patients with kidney impairment. • Neurological Effects: Monitor for signs of neurotoxicity, including dizziness and muscle weakness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Injection site reactions • Renal toxicity • Neurological symptoms (e.g., confusion, dizziness) • Gastrointestinal disturbances (e.g., nausea, vomiting) • Muscle weakness

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General Medicine

Clocivir 500 Injection is an intravenous formulation containing Acyclovir 500 mg, manufactured by American Remedies. It is primarily used to treat severe viral infections caused by herpes viruses. ________________________________________ 🩺 Uses of Clocivir 500 Injection Clocivir 500 Injection is indicated for: • Herpes Simplex Infections in Immunocompromised Patients: Including severe primary or non-primary genital herpes. • Herpes Simplex Encephalitis: A serious brain infection caused by the herpes simplex virus. • Neonatal Herpes Simplex Virus Infection: In newborns. • Varicella-Zoster Infections in Immunocompromised Patients: Such as severe cases of chickenpox or shingles. • Severe Herpes Zoster (Shingles): In immunocompetent patients with very severe acute local or systemic manifestations. ________________________________________ 💊 Mechanism of Action Acyclovir, the active ingredient in Clocivir, is a synthetic purine nucleoside analogue. It exerts its antiviral effects by inhibiting viral DNA synthesis, thereby preventing the replication of herpes viruses. Acyclovir is converted to its active form, Acyclovir Triphosphate, within infected cells, which then interferes with viral DNA polymerase. ________________________________________ ⚠️ Precautions • Administration: Clocivir 500 Injection should be administered by a healthcare professional through slow intravenous infusion over a 1-hour period to minimize the risk of kidney damage. • Hydration: Adequate hydration is essential during treatment to prevent dehydration and kidney damage. • Kidney Function: Use with caution in patients with pre-existing kidney conditions. • Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

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General Medicine

Clocivir 250 Injection is an intravenous formulation containing Acyclovir 250 mg, manufactured by American Remedies. It is primarily used to treat severe viral infections caused by herpes viruses. ________________________________________ 🩺 Uses of Clocivir 250 Injection Clocivir 250 Injection is indicated for: • Herpes Simplex Virus Infections: Including severe cases in immunocompromised patients. • Genital Herpes: Especially primary or non-primary severe cases. • Herpes Zoster (Shingles): In immunocompetent patients with severe manifestations. • Chickenpox (Varicella Zoster Virus Infection): Particularly in immunocompromised individuals. • Herpes Simplex Encephalitis: A severe brain infection caused by the herpes simplex virus. ________________________________________ 💊 Mechanism of Action Acyclovir, the active ingredient in Clocivir, is a synthetic purine nucleoside analogue. It exerts its antiviral effects by inhibiting viral DNA synthesis, thereby preventing the replication of herpes viruses. Acyclovir is converted to its active form, Acyclovir Triphosphate, within infected cells, which then interferes with viral DNA polymerase . ________________________________________ ⚠️ Precautions • Administration: Clocivir 250 Injection should be administered by a healthcare professional through slow intravenous infusion over a 1-hour period to minimize the risk of kidney damage . • Hydration: Adequate hydration is essential during treatment to prevent dehydration and kidney damage. • Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning to conceive, or breastfeeding. • Drug Interactions: Inform your healthcare provider about all other medications you are taking to avoid potential interactions.

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General Medicine

Cezocalm Injection is a brand name for Chlorpromazine Hydrochloride Injection, manufactured by American Remedies. Chlorpromazine is a first-generation antipsychotic medication belonging to the phenothiazine class. ________________________________________ 🩺 Uses of Cezocalm Injection Cezocalm Injection is primarily used to manage various psychiatric and neurological conditions, including: • Schizophrenia: A chronic mental health disorder characterized by distorted thinking, perception, emotions, and behavior. • Acute Psychotic Episodes: Short-term episodes of severe mental disturbances. • Manic Episodes in Bipolar Disorder: Periods of abnormally elevated mood and energy levels. • Severe Behavioral Problems in Children: Such as hyperactivity and aggression. • Severe Nausea and Vomiting: Especially when other treatments are ineffective. Hiccups: Persistent and intractable cases. • Preoperative Sedation: To relax patients before surgery. ________________________________________ 💊 Mechanism of Action Chlorpromazine works by: Blocking dopamine receptors in the brain, which helps in reducing symptoms of psychosis. • Exhibiting sedative properties by affecting various neurotransmitter systems. ________________________________________ ⚠️ Precautions and Side Effects Before administering Cezocalm Injection, inform your healthcare provider if you have: • Allergies to chlorpromazine or other medications. • A history of liver or kidney disease. • Heart conditions, especially arrhythmias. • Blood disorders. • Seizure disorders. • Pregnancy or breastfeeding status. Common side effects may include: Drowsiness or sedation. • Dizziness. • Dry mouth. • Constipation. • Hypotension (low blood pressure). • Extrapyramidal symptoms (e.g., tremors, rigidity). • Photosensitivity.

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General Medicine

Canpam Injection is a medication containing Pralidoxime Iodide 500 mg/20 ml, manufactured by American Remedies. It is primarily used as an antidote in cases of organophosphate poisoning. ________________________________________ 🩺 Uses of Canpam Injection Canpam Injection is administered to counteract the toxic effects of organophosphates, which are commonly found in certain pesticides and nerve agents. When these substances inhibit acetylcholinesterase, an enzyme essential for nerve function, they lead to an accumulation of acetylcholine, causing overstimulation of muscles and glands. Pralidoxime works by reactivating acetylcholinesterase, thereby alleviating symptoms such as muscle weakness, respiratory distress, and convulsions. ________________________________________ ⚠️ Precautions Before administering Canpam Injection, healthcare providers should assess for: • Allergies to pralidoxime or related compounds. • Kidney or liver impairments, as dosage adjustments may be necessary. • Concurrent use of other medications, to avoid potential drug interactions.

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Eye Care

Atropine Sulphate Eye Drops IP refers to atropine sulfate in its pharmaceutical grade form, used specifically for ocular (eye) treatments. 'IP' stands for Indian Pharmacopoeia, which is a set of standards for medicines in India, ensuring quality, safety, and efficacy. Uses of Atropine Sulphate Eye Drops IP: Pupil Dilation (Mydriasis): One of the most common uses of atropine eye drops is to dilate the pupil for diagnostic purposes, especially during an eye examination. The drops relax the muscles in the eye, allowing for better visibility of the retina and optic nerve. Treatment of Uveitis and Iritis: Atropine is frequently prescribed for conditions such as uveitis and iritis (inflammation of the iris). The medication helps relieve pain and inflammation and prevents the iris from sticking to the lens. This is important to avoid complications like synechiae (adhesions between the iris and lens). Cycloplegia: Cycloplegia is the paralysis of the ciliary muscle that controls focusing. Atropine is used to temporarily paralyze this muscle during eye exams to assess the retina or the overall refractive status of the eye. Prevention of Post-Surgical Complications: After certain eye surgeries, atropine can help in preventing the formation of adhesions between the iris and the lens, which can occur after surgery like cataract surgery. It aids in recovery and minimizes the risk of complications. Management of Myopia (Nearsightedness): In some cases, atropine drops have been used in research to slow the progression of myopia (nearsightedness) in children, though this is less common in routine practice. How It Works: Atropine is an anticholinergic drug that blocks the action of acetylcholine, a neurotransmitter involved in eye muscle contraction. By inhibiting the contraction of the pupil’s sphincter muscle and the ciliary muscle, atropine causes pupil dilation and paralysis of accommodation, allowing for eye relaxation and easier examination. Dosage: The dosage depends on the condition being treated. Typically, for eye exams, one or two drops are applied to each eye, and the effects (pupil dilation) usually last for several hours. For therapeutic use, your doctor will prescribe the frequency and duration based on the specific condition. Precautions: Side Effects: Common side effects include blurred vision, sensitivity to light (photophobia), and dry mouth. In some cases, you may experience increased intraocular pressure or tachycardia (rapid heart rate). Avoid Exposure to Bright Light: Since atropine causes pupil dilation, you may be more sensitive to light. It's advisable to wear sunglasses when outside in bright conditions. Do Not Drive: Due to blurred vision, avoid driving or operating heavy machinery until the effects wear off. Systemic Effects: Rarely, atropine can be absorbed into the bloodstream, leading to symptoms such as confusion, rapid heart rate, or dry skin. If you experience these symptoms, seek medical help immediately. Contraindications: Glaucoma: Atropine should be used with caution, or avoided, in individuals with narrow-angle glaucoma or other eye conditions that affect intraocular pressure. Pregnancy and Breastfeeding: While atropine is generally considered safe in therapeutic doses, it’s essential to consult your doctor if you are pregnant or breastfeeding before using the drops.

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