INTRODUCTION ABOUT TAXONAB 100MG INJECTION TAXONAB 100MG INJECTION contains Paclitaxel which belongs to a group of anti-cancer medicines called Taxanes. TAXONAB 100MG INJECTION is used to manage ovarian and breast cancer as a first line of therapy and as a second line of management when platinum containing medicines (such as cisplatin) or anthracyclines are insufficient to manage the disease in affected individuals. TAXONAB 100MG INJECTION is also used to manage advanced NSCLC (non-small cell lung cancer) when surgery/radiation therapy is not suitable. The medicine is also indicated for use to manage AIDS-related Kaposi’s sarcoma when other managements (such as anthracyclines) are insufficient to manage the disease in affected individuals. TAXONAB 100MG INJECTION is not recommended for use in patients allergic to paclitaxel and polyoxyethylated castor oil. It is also not recommended for use in patients with few white blood cells count and serious & uncontrolled infection. The medicine is also not used in patients suffering from severe liver disease. Before receiving TAXONAB 100MG INJECTION, inform your doctor if you had previously received radiation to your chest and/or suffering from thrombocytopenia (low platelet count)/acute infections (such as herpes zoster, chickenpox, herpes), kidney problems (such as chronic kidney disease), liver problems (such as mild/moderate hepatic impairment) and/or heart problems (such as severe coronary artery disease, myocardial infarction and arrhythmias). TAXONAB 100MG INJECTION is not recommended for use during pregnancy. Women of child-bearing potential should use effective contraception method while receiving TAXONAB 100MG INJECTION which should be continued for next-6 months after completing the management. The medicine is also not recommended for use in breastfeeding women. TAXONAB 100MG INJECTION is also not recommended for use in children and adolescents (aged below 18 years). The medicine can be used with caution in elderly patients (aged above 65 years) after consulting the doctor. The most common side effects of receiving TAXONAB 100MG INJECTION are minor allergic reactions (such as flushing, rash, itching), shortness of breath, sore throat/mouth ulcers, diarrhea, nausea, vomiting and/or loss of hair. Consult your doctor if any of these symptoms worsen. USES OF TAXONAB 100MG INJECTION Manage ovarian and breast cancer. Manage advanced NSCLC (non-small cell lung cancer) Manage AIDS-related Kaposi’s sarcoma in affected individuals. HOW TAXONAB 100MG INJECTION WORKS TAXONAB 100MG INJECTION works by interfering with the microtubule structures in the cell (substance which aids cancer cells to divide and multiply) thus inhibiting the growth of cancer cells and managing its spread in affected individuals. DIRECTIONS FOR USE TAXONAB 100MG INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF TAXONAB 100MG INJECTION COMMON minor allergic reactions such as flushing, rash and/or itching infections such as upper respiratory infection, urinary tract infection shortness of breath sore throat/mouth ulcers, sore and red mouth diarrhea, nausea, vomiting loss of hair pain in the muscles, cramps, joints fever, severe chills, headache, dizziness, tiredness, looking pale bleeding, bruising more easily than normal signs of peripheral neuropathy such as numbness, tingling/weakness in arms and legs temporary mild nail change and skin changes reactions at injection sites such as localized swelling, pain and/or redness of the skin. UNCOMMON septic shock (severe drop in blood pressure) due to infections racing heartbeat, rapid beating of the heart, respiratory distress, heart attack, heart block fatigue, sweating, fainting, significant allergic reactions, phlebitis (inflammation of a vein), swelling of the face, lips, mouth, tongue and/or throat back pain, chest pain, pain around hands and feet, chills, abdominal pain. RARE febrile neutropenia (type of fever) due to low white blood cell count associated with fever and increased risk of infection motor neuropathy (disease that affects your body’s motor nerves) pulmonary embolism (blockade of lung artery), lung fibrosis (damaged/scarred lung tissue), interstitial pneumonia (scarring of lung tissue), pleural effusion (build of fluid between lungs and chest) bowel obstruction, bowel perforation, inflammation of colon, inflammation of the pancreas (pancreatitis) skin redness peritonitis (inflammation of abdominal layer) fever, dehydration, weakness anaphylactic reactions (life threatening allergic reaction). HOW TO MANAGE SIDE EFFECTS Diarrhea: Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult your doctor and inform them if the symptom gets worse.

INTRODUCTION ABOUT ENCORATE CHRONO 500MG TABLET ENCORATE CHRONO 500MG TABLET is a combination of Sodium valproate and Valproic acid, which belong to the group of medicines called Anticonvulsant/Antiepileptic drugs. It is used to manage epilepsy in adults and children. It is also used to manage bipolar disorders. Epilepsy is an abnormal electrical activity in the brain and nervous system. The symptoms may include temporary confusion, muscle stiffness, jerky movements in legs or arms, loss of consciousness, psychological symptoms (such as anxiety or fear), etc. ENCORATE CHRONO 500MG TABLET is not recommended for use in patients with liver problems or with a family history of liver problems, porphyria (a hereditary disease that affects the skin or nervous system), blood coagulation or clotting disorders, pancreatic diseases (inflammation of the pancreas), urea cycle disorder (a genetic disorder) or Alpers-Huttenlocher syndrome (a rare disorder that affects brain, liver & muscles), etc. ENCORATE CHRONO 500MG TABLET should be used with caution in patients with kidney problems or lung diseases (such as chronic obstructive pulmonary disease) and diabetes. ENCORATE CHRONO 500MG TABLET is also not recommended for use in pregnant and breastfeeding women. It should be used with caution in children (below 2 years of age). Consult your doctor before taking the medicine. The common side effects of taking ENCORATE CHRONO 500MG TABLET may include dizziness, headache, sleep disorders, clumsiness/unsteadiness, trembling of hands and arms and nervousness. Consult your doctor if any of the symptoms worsen or persist. USES OF ENCORATE CHRONO 500MG TABLET Manage epilepsy Manage bipolar disorders HOW ENCORATE CHRONO 500MG TABLET WORKS ENCORATE CHRONO 500MG TABLET helps in managing epilepsy, where sodium valproate and valproic acid effectively increases the GABA (a neurotransmitter/chemical messenger) concentration in the central nervous system by reducing its degradation. It also blocks certain ion channels which reduce high-frequency neuronal activity in the brain, thereby reliving seizure activity. DIRECTIONS FOR USE Take ENCORATE CHRONO 500MG TABLET as advised by your physician. Swallow the medicine with a glass of water with or after food. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition. SIDE EFFECTS OF ENCORATE CHRONO 500MG TABLET COMMON headache sleep disorders clumsiness or unsteadiness trembling of hands and arms nervousness changing moods blurred vision ringing in ears deafness dizziness flu abdominal or stomach pain heartburn nausea and vomiting diarrhoea skin rash hair loss or thinning of hair back pain change in menstrual periods lack or loss of strength mental confusion aggression convulsion memory problems becoming unreactive bedwetting signs of liver damage such as skin and eyes that appear yellowish (jaundice), abdominal pain and swelling. signs of inflammation of the pancreas (pancreatitis) such as upper abdominal pain, abdomen tenderness, fever and rapid pulse signs of Fanconi syndrome (a disorder of kidney tubes) such as excessive thirst, urination, vomiting overgrown gum tissue agitation disturbance in attention abnormal behaviour hyperactivity learning disorder UNCOMMON unusual bleeding or bruising abnormal dreams anxiety feeling sad irritability pain in joints cough constipation dry eyes spots before the eyes ear infection ear pain runny nose dental pain bloating muscle pains or stiffness tiredness weight gain or loss learning disorder coma loss of muscle control brittle bones and fractures shortness of breath chest pain blood clotting problems RARE Stop taking ENCORATE CHRONO 500MG TABLET and contact your doctor if you experience any of the following side effects: signs of allergic reactions such as swelling of the face, lips, eyelids, throat and tongue, which may cause difficulty in breathing and swallowing signs of altered levels of ammonia in the blood characterized by vomiting, balance issues and lack of alertness signs of liver problems characterized by nausea, vomiting, tiredness, sleepiness, weakness, stomach pain, yellowing of the skin or whites of the eye signs of inflammation of the pancreas characterized by acute abdominal pain chest pain shortness of breath hallucinations suicidal thoughts psychosis (mental disorder causing disconnection from reality) toxic epidermal necrolysis (life-threatening skin disorder causing widespread skin pain, rashes, blisters, sores and crusting) Steven-Johnson syndrome (a skin disorder characterized by painful rashes and blisters on the skin) anaphylaxis (severe allergic reaction characterized by shortness of breath, fainting or fastened heartbeat) erythema multiforme (a skin condition characterized by raised red rashes on the skin)

Paristin-Z (Sulphacetamide & Zinc Sulphate) Eye Drops Uses: • Bacterial Eye Infections: Paristin-Z is primarily used to treat bacterial eye infections such as conjunctivitis (pink eye), blepharitis (inflammation of the eyelids), and other superficial eye infections caused by susceptible bacteria. • Eye Irritation Relief: The combination of Sulphacetamide and Zinc Sulphate helps alleviate symptoms like redness, itching, and discharge associated with eye infections. Dosage: • Typical Dosage: Instill 1–2 drops into the affected eye(s) every 3 to 4 hours, or as directed by your healthcare provider. • Application Method: 1. Wash your hands thoroughly before use. 2. Tilt your head back and gently pull down the lower eyelid to create a small pocket. 3. Place the dropper tip near the eye without touching it. 4. Squeeze the prescribed number of drops into the pocket. 5. Close your eye and blink several times to spread the solution evenly. Precautions: • Allergic Reactions: If you experience signs of an allergic reaction such as rash, itching, swelling, or difficulty breathing, discontinue use and consult your doctor immediately. • Contact Lenses: Avoid wearing contact lenses during the course of treatment unless advised otherwise by your healthcare provider. • Pregnancy and Breastfeeding: Consult your doctor before using Paristin-Z if you are pregnant or breastfeeding. Side Effects: • Common Side Effects: o Temporary burning or stinging upon application. o Mild irritation or redness. o Temporary blurred vision. • Serious Side Effects: o Persistent eye pain or swelling. o Worsening of vision. o Signs of an allergic reaction (rash, itching, swelling).

Paristin-C (Sulphacetamide & Chloramphenicol) Eye/Ear Drops Paristin-C is a combination ophthalmic and otic solution containing Sulphacetamide (20% w/v) and Chloramphenicol (0.5% w/v). It is primarily used to treat bacterial infections of the eye and ear. ________________________________________ 🔍 Uses • Bacterial Eye Infections: Effective in treating conditions such as conjunctivitis (pink eye), blepharitis (inflammation of the eyelids), and other superficial eye infections caused by susceptible bacteria. • Bacterial Ear Infections: Used to treat external ear infections (otitis externa) caused by bacteria. ________________________________________ 💧 Dosage and Administration • For Eye Infections: o Instill 1–2 drops into the affected eye(s) every 3 to 4 hours, or as directed by your healthcare provider. o Continue the full course of treatment even if symptoms improve to ensure complete eradication of the infection. o Apply 2–3 drops into the affected ear canal, 3 to 4 times daily, or as prescribed by your doctor. o Keep the head tilted for a few minutes to allow the medication to reach the affected area. ________________________________________ ⚠️ Side Effects and Precautions • Common Side Effects: o Mild irritation or burning sensation upon application. o Temporary blurred vision (for eye drops). o Ear discomfort or itching (for ear drops). • Serious Side Effects: o Signs of an allergic reaction, such as rash, itching, swelling, or difficulty breathing. o Persistent redness or discomfort in the eye or ear. • Precautions: o Do not touch the dropper tip to any surface to avoid contamination. o If using contact lenses, remove them before applying the eye drops and wait at least 15 minutes before reinserting. o Consult your healthcare provider before use if you are pregnant, breastfeeding, or have a history of allergies to sulfonamides or chloramphenicol. ________________________________________

Povar (Povidone Iodine) Eye Drops are antiseptic ophthalmic solutions primarily used for preoperative and postoperative eye care, as well as for certain eye infections. The active ingredient, povidone-iodine, is a broad-spectrum antimicrobial agent effective against bacteria, viruses, and fungi. ________________________________________ 🔍 Uses of Povidone Iodine Eye Drops 1. Preoperative Antisepsis Applied to the ocular surface before eye surgeries such as cataract or glaucoma procedures to reduce the risk of postoperative infections. 2. Postoperative Care Used after eye surgeries to prevent infection and promote healing of the ocular surface. 3. Treatment of Conjunctivitis In some cases, povidone-iodine eye drops are used to treat bacterial or viral conjunctivitis, commonly known as pink eye. 4. Prevention of Ophthalmia Neonatorum Instilled in newborns' eyes shortly after birth to prevent gonococcal or chlamydial eye infections. ________________________________________ ⚠️ Safety and Side Effects • Common Side Effects Temporary stinging or burning sensation upon application. Mild irritation or redness of the eye. Temporary yellow discoloration of the whites of the eyes or surrounding skin. Serious Side Effects Signs of an allergic reaction, such as rash, itching, swelling, or difficulty breathing. If any of these occur, seek immediate medical attention. Precautions o Do not use if allergic to iodine or any components of the product. o Use with caution in individuals with thyroid disorders due to potential iodine absorption. o Not recommended for use in infants under one month of age. o Avoid concurrent use with other antiseptic eye drops containing mercury-based preservatives or sodium thiosulfate.

Pipracan 4.5 Injection is a combination antibiotic medication containing Piperacillin (4 g) and Tazobactam (0.5 g). This formulation is used to treat a wide range of serious bacterial infections that may not respond to other antibiotics. ________________________________________ 🔹 Common Uses Pipracan 4.5 Injection is prescribed for: • Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) • Urinary tract infections (UTIs) • Intra-abdominal infections (e.g., peritonitis) • Skin and soft tissue infections, including diabetic foot infections • Gynecological infections, such as uterine infections • Bone and joint infections • Bloodstream infections (bacteremia) It is also used for prophylactic treatment in surgical procedures to prevent infections. ________________________________________ 🔹 How It Works • Piperacillin is a broad-spectrum penicillin antibiotic that inhibits bacterial cell wall synthesis, leading to bacterial cell death. • Tazobactam is a beta-lactamase inhibitor that protects piperacillin from degradation by beta-lactamase enzymes produced by certain bacteria, thereby enhancing its efficacy. This combination allows Pipracan 4.5 to target a wide array of bacteria, including those resistant to other antibiotics. ________________________________________ 🔹 Administration Pipracan 4.5 Injection is administered intravenously by a healthcare professional. The dosage and duration of treatment depend on the type and severity of the infection, as well as the patient's medical condition. Self-administration is not recommended. ________________________________________ 🔹 Side Effects Common side effects may include: • Nausea or vomiting • Diarrhea • Rash or itching • Pain, redness, or swelling at the injection site Serious side effects are rare but can include allergic reactions, liver enzyme abnormalities, or blood disorders. Seek immediate medical attention if you experience symptoms like difficulty breathing, swelling of the face or throat, or unusual bruising or bleeding. ________________________________________ 🔹 Precautions Before using Pipracan 4.5 Injection, inform your doctor if you have: Allergies to penicillins or beta-lactam antibiotics • Kidney or liver disease • A history of gastrointestinal diseases, such as colitis • Bleeding disorders • Undergoing dialysisUse during pregnancy and breastfeeding should be discussed with your healthcare provider. The medication should only be used if the potential benefits justify the potential risks.

Paracan IV is an intravenous (IV) injection that contains paracetamol (also known as acetaminophen). It's commonly used for: 1. Pain Relief: • Post-operative pain: Helps manage pain following surgeries. • Headaches: Effective for treating mild to moderate headaches. • Muscle and joint pain: Used for muscle strains, back pain, or arthritis pain. • Other pain types: Such as toothaches, menstrual cramps, and nerve pain. 2. Fever Reduction: • Paracan IV is used to reduce fever in cases of infections, inflammation, or after surgical procedures. How It Works: Paracan IV works by inhibiting the production of prostaglandins (chemicals in the body that cause pain and inflammation). This provides both pain relief (analgesic effect) and fever reduction (antipyretic effect). Administration: Paracan IV is given through an intravenous (IV) line, typically in a hospital or clinical setting. The dosage depends on the patient's condition, but it's commonly administered when oral medication is not an option. Side Effects: While generally safe when used as directed, it can cause side effects, such as: • Headaches • Nausea or vomiting • Injection site reactions (pain, redness, or swelling) If you experience severe allergic reactions (e.g., difficulty breathing, swelling), immediate medical attention is required. Precautions: Before use, inform your healthcare provider if you have: • Liver or kidney disease • Alcohol use disorder • Allergies to paracetamol or any components of the injection Always use under medical supervision, especially for pregnant or breastfeeding women.

Ondican 2 Injection is a brand of Ondansetron 2 mg/2 mL Injection, manufactured by American Remedies. Ondansetron is a 5-HT₃ receptor antagonist commonly used as an antiemetic to prevent and treat nausea and vomiting associated with various medical conditions. ________________________________________ ✅ Primary Uses Ondican 2 Injection is indicated for: • Chemotherapy-Induced Nausea and Vomiting (CINV): To prevent and treat nausea and vomiting caused by cancer chemotherapy. Radiotherapy-Induced Nausea and Vomiting (RINV): To prevent and treat nausea and vomiting associated with radiation therapy. Postoperative Nausea and Vomiting (PONV): To prevent and treat nausea and vomiting following surgical procedures. These indications are supported by clinical guidelines and pharmacological references. ________________________________________ ⚙️ Mechanism of Action Ondansetron works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting. It specifically inhibits serotonin receptors in the chemoreceptor trigger zone (CTZ) in the brain, thereby preventing the sensation of nausea and the act of vomiting. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Allergy: Do not use if allergic to ondansetron or other 5-HT₃ receptor antagonists. • Cardiac Conditions: Use with caution in patients with a history of heart problems, as ondansetron may affect heart rhythm. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Headache • Constipation • DizzinessFatigue Serious Side Effects: • Allergic reactions (rash, itching, swelling) Severe dizziness or fainting • Irregular heartbeat Seek immediate medical attention if any serious side effects occur.

MNOphyllin Injection is a brand of Aminophylline Injection, manufactured by American Remedies. Aminophylline is a bronchodilator that works by relaxing the muscles of the air passages in the lungs, making it easier to breathe. ________________________________________ ✅ Primary Uses MNOphyllin Injection is primarily used for: • Asthma: A chronic condition where the airways become inflamed and narrow, leading to difficulty in breathing. • Chronic Obstructive Pulmonary Disease (COPD): A group of lung diseases that block airflow and make breathing difficult. • Bronchospasm: A condition where the muscles around the airways tighten, leading to wheezing and shortness of breath. It is administered intravenously in a hospital setting under medical supervision. ________________________________________ ⚙️ Mechanism of Action Aminophylline works by: • Relaxing the bronchial muscles: This leads to the widening of the air passages, making it easier to breathe. • Increasing the strength of the diaphragm: This enhances the ability to breathe effectively. • Reducing airway responsiveness to irritants: This helps in decreasing inflammation and bronchoconstriction. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Medical History: Inform your doctor if you have a history of heart disease, liver or kidney disorders, or seizures. • Pregnancy and Breastfeeding: Consult your doctor before use if pregnant or breastfeeding. • Drug Interactions: Certain medications can interact with Aminophylline, so it's essential to inform your healthcare provider about all medicines you are taking. Common Side Effects: • Nausea • Vomiting • Headache • Restlessness • Dizziness Serious Side Effects: • Irregular heartbeats • Seizures • Severe allergic reactions If you experience any of these serious side effects, seek immediate medical attention.