'bone therapeutic effects'

ALKACEL 50MG INJECTION belongs to a class of alkylating agents, also known as chemotherapeutic agents. It is used to treat various cancer conditions such as multiple myeloma ((a type of cancer that develops from cells in the bone marrow called plasma cells), advanced cancer of the ovaries, childhood neuroblastoma (cancer of the nervous system), malignant melanoma (skin cancer) and soft tissue sarcoma. Cancer is a genetic change in which the body's cells divide uncontrollably and spread into surrounding tissues. ALKACEL 50MG INJECTION is also used to destroy bone marrow and cancer cells in preparation for a bone marrow transplant in people with multiple myeloma. ALKACEL 50MG INJECTION contains Melphalan, which reduces the number of abnormal cells your body makes. Thus, it treats cancer efficiently. ALKACEL 50MG INJECTION will be administered only in a hospital setting by an experienced healthcare professional. The most common adverse reactions observed in patients treated with ALKACEL 50MG INJECTION are neutrophil count decreased, white blood cell count decreased, platelet count decreased, lymphocyte count decreased, diarrhoea, fatigue, anaemia, nausea, vomiting and hypokalemia. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if any of these side effects persist or worsen.

Introduction to Xolnic 4mg Injection Xolnic 4mg contains the active substance Zoledronic Acid. It belongs to the group of substances called bisphosphonates. It is used to reduce the amount of calcium in the blood in adult patients where it is too high due to the presence of a tumor. Tumors can accelerate normal bone change in such a way that the release of calcium from bone is increased. This condition is known as tumor-induced hypercalcemia (TIH). It is also used to prevent bone complications in adult patients with multiple myeloma and bone metastases from solid tumors (spread of cancer from the primary site to the bone), in addition to standard cancer therapy. Xolnic 4mg is also indicated to prevent or treat osteoporosis (a condition in which the bones become thin and weak and break easily) in women who have undergone menopause. It is also used to treat osteoporosis in men. It is used to treat Paget’s disease of bone (a condition in which the bones are soft and weak and may be deformed, painful, or easily broken). Other uses include treating or preventing osteoporosis in men and women taking glucocorticoids (a corticosteroid medication that may cause osteoporosis). Do not take this injection if you are allergic to zoledronic acid, another bisphosphonate, or any other ingredients of this medicine and if you are pregnant or breastfeeding. Before initiating the treatment, inform your physician if you have kidney or liver problems, bone diseases, pain, swelling, or jaw numbness. This medicine is not recommended for use in adolescents and children below the age of 18 years. Xolnic 4mg is not cancer chemotherapy and will not slow or stop the spread of cancer. However, it can be used to treat bone diseases in patients with cancer. Uses of Xolnic 4mg Injection Treat hypercalcemia of malignancy Multiple myeloma Bone metastases from solid tumors Osteoporosis in postmenopausal women Osteoporosis in men Paget’s disease of bone Therapeutic Effects of Xolnic 4mg Injection Xolnic 4mg primarily inhibits bone resorption. It works by slowing bone breakdown, increasing bone density (thickness), and decreasing the amount of calcium released from the bones into the blood. Interaction of Xolnic 4mg Injection with other drugs Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications like aminoglycosides, loop diuretics, and nephrotoxic drugs may interact with Xolnic 4mg and reduce its effectiveness by causing undesirable side effects. More Information about Xolnic 4mg Injection Store Xolnic 4mg at room temperature (20°C to 25°C) keep the injection away from the reach of children and pets. If you have missed any dosing appointments, inform your doctor and schedule immediately. How to consume Xolnic 4mg Injection It should only be administered by a trained doctor or nurse. It will be given as a drip (infusion) into your vein. Your doctor will decide the dose and duration of the treatment based on your disease severity and other factors. Do not self-administer the medication. Safety Advices for Xolnic 4mg Injection Image Not Available Pregnancy Xolnic 4mg is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Image Not Available Breast Feeding Breastfeeding is not recommended in patients taking Xolnic 4mg because the medicine passes into the breast milk in small amounts and may harm your baby. Image Not Available Lungs It is unknown whether Xolnic 4mg can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment. Image Not Available Liver It is unknown whether Xolnic 4mg can be used in patients with liver disorders. Inform your physician if you have liver problems before initiating the therapy. Image Not Available Alcohol Caution is advised when consuming alcohol with Xolnic 4mg. Please consult your doctor. Image Not Available Driving It is unsafe to drive or operate heavy machinery after using Xolnic 4mg as this medicine causes drowsiness and sleepiness. Side Effects of Xolnic 4mg Injection Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Nausea, vomiting Fatigue Anemia Bone pain Constipation, diarrhea dyspnea, and fever Swelling in the legs and feet Decreased weight Abdominal pain Muscle pain Tiredness Serious Changes in heart rhythm Severe hypersensitivity skin reactions Decreased calcium levels Severe bone pain Severe kidney problems Unusual fractures of the bone

Introduction to Cytraze 1000mg Injection Cytraze 1000mg injection contains the active substance Cytarabine. It is an antineoplastic drug that belongs to the class antimetabolite. It is used alone or with other chemotherapy medications to treat certain types of leukemias (a type of blood cancer with too many white blood cells), including acute myeloid leukemia (AML) and chronic myelogenous leukemia (CML). It is also indicated to use alone or with other chemotherapy drugs to treat and prevent meningeal leukemia (cancer in the membrane that covers and protects the spinal cord and brain). Do not take Cytraze 1000mg injection if you are allergic to Cytarabine or any other ingredients of this medicine. Inform your physician if you have difficulties in body coordination, or taking any other anti-cancer medications, decreased bone marrow functioning, have liver problems, or have undergone dialysis immediately before or after treatment with this medicine. Cytraze 1000mg injection may cause an increased uric acid level in your blood, your doctor will tell you if you need to take any medicine to control this. Notify your physician if you have sudden signs of allergy, such as rash, itching, or hives on the skin, swelling of the face, lips, mouth, or throat, shortness of breath, or wheezing. It is unknown whether this medicine can be administered in patients with kidney failure, inform your doctor if you have any kidney diseases. Uses of Cytraze 1000mg Injection Acute myeloid leukemia (AML) Chronic myelogenous leukemia (CML) Meningeal leukemia Therapeutic Effects of Cytraze 1000mg Injection Cytraze 1000mg injection is a cytotoxic drug that acts by primarily killing cells undergoing DNA synthesis. It works by slowing or stopping the growth of cancer cells in your body. Interaction of Cytraze 1000mg Injection with other drugs Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, vaccines, and herbal products. Certain medications may interact with the effects of Cytraze 1000mg injection and reduce its effectiveness by causing undesirable side effects. Inform your physician if you are using digoxin. More Information about Cytraze 1000mg Injection Store Cytraze 1000mg injection at room temperature (25°C) Do not refrigerate or freeze. Keep the injection away from the reach of children and pets. If you forgot to take a dose on the scheduled day, contact your physician and reschedule the dose. Do not take a double dose to make up for a forgotten dose. How to consume Cytraze 1000mg Injection Cytraze 1000mg injection will be given to you in a hospital setting by a trained healthcare professional. This medicine may be given by solution for injection/infusion (using a syringe) under the skin (subcutaneous) or into a vein (intravenously) or into a muscle (intramuscularly), or into the spine (intrathecal). Your doctor will decide the dose, route of administration, and duration of the treatment based on your disease condition, severity, and other factors. Safety Advices for Cytraze 1000mg Injection Image Not Available Pregnancy Cytraze 1000mg injection is unsafe to administer in pregnant women because it may cause birth defects. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 6 months after your last dose is necessary. Image Not Available Breast Feeding Breastfeeding is not recommended in patients taking Cytraze 1000mg injection because the medicine passes into the breast milk in small amounts and may harm your baby. Image Not Available Lungs It is unknown whether Cytraze 1000mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment. Image Not Available Liver It is unknown whether Cytraze 1000mg injection can be used in patients with liver disorders. Consult your doctor if you have any liver diseases before starting the treatment. Image Not Available Alcohol It is not known whether it is safe to consume alcohol with Cytraze 1000mg injection. Please consult your doctor. Image Not Available Driving Cytraze 1000mg injection does not affect your ability to drive or use machinery. If you are affected, consult your doctor for more advice. Side Effects of Cytraze 1000mg Injection Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Fever Loss of appetite, abdominal pain Swallowing difficulties Nausea, vomiting Diarrhoea Inflammation or ulceration in the mouth or anus High blood uric acid levels Hair loss Skin rashes Speaking difficulties Inflammation in the vein Serious Swelling and irritation of the skin Increased blood uric acid levels Blisters of the skin Irregular heartbeat Lung diseases Anemia

What is Magprol CR 400 tablet Magprol CR 400 is an Anti-epileptic medication primarily used to manage Epilepsy and Bipolar Disorder and prevent Migraines. It contains Magnesium Valproate as a potent active ingredient and is manufactured by Intas Pharmaceuticals Ltd. It works by stabilizing abnormal brain activity, thereby reducing seizures and mood swings. You can use this medicine after consulting your doctor. Your doctor knows your health condition and can prescribe the ideal dosage of this medicine. You can take it alone or alongside other treatments. Furthermore, you may consume it with or without food. Your doctor determines the appropriate dosage, which may gradually increase until your condition is stable. Although it may take several weeks to see visible results, it is crucial to continue taking the medication regularly, even if symptoms improve. Sudden discontinuation of Magprol can lead to a resurgence of seizures or worsening of Bipolar symptoms. Like all medications, Magprol may also cause some side effects. Some common side effects include skin rashes, headaches, nausea, sleep disturbances, dizziness, and drowsiness. While most side effects are temporary, persistent issues should be discussed with your doctor. Furthermore, long-term use may lead to bone weakness (Osteoporosis), increasing fracture risk. You should inform their doctor about any pre-existing kidney or liver conditions, mental health issues, or other medications being taken, including contraceptives. Women during pregnancy or breastfeeding stages may require dosage adjustments. Be extremely cautious when driving or operating machinery, as the medication may cause drowsiness or dizziness. Regular blood tests are also necessary to monitor treatment response. What are the benefits of Magprol CR 400 tablet Magprol CR 400 tablet is primarily used in the treatment of Epilepsy, Bipolar Disorder, and Migraine prevention. It modulates neurotransmitter activity in the brain and controls seizures. Furthermore, it enhances the effects of Gamma-Aminobutyric Acid (GABA), a key inhibitory neurotransmitter that promotes calmness. This action helps to stabilize abnormal electrical activity. Thus, it reduces the severity and frequency of seizures in people with Epilepsy. Additionally, by balancing mood-regulating chemicals, it effectively mitigates extreme mood swings associated with Bipolar Disorder. Furthermore, its ability to inhibit excessive nerve signal transmission contributes to Migraine prevention, reducing headache attacks. While it may take several weeks to achieve its full therapeutic effects, consistent use is essential for optimal results. How to take Magprol CR 400 tablet You need to take Magprol tablets only after consulting a doctor. Your doctor can prescribe the ideal dosage based on your medical condition and response. For the best results, take the tablet in the following ways: Take Magprol when your doctor prescribes it, usually in the morning and the evening. Swallow the 400 mg tablet as a whole with a glass of water. Avoid breaking, crushing, or chewing the tablet. You can take this tablet with or without food. However, be sure to take this at a fixed time. You need to adhere to your doctor’s prescription and take this medicine at the same time regularly. What are the side effects of Magprol CR 400 tablet Like all Anti-epileptic medications, these tablets may also cause specific side effects in some people. These side effects are mild, well-tolerated, and temporary. They disappear as the body gets used to the new medicine or its adjusted dosage. Some common Magprol CR 400 tablet side effects are as follows: Headache Vomiting Nausea Hair loss Dizziness Fatigue Loss of appetite Irritation and agitation Blurred vision If these side effects worsen or persist for longer than usual, consult your doctor and seek immediate medical treatment. Safety Advice Liver problemsLiver disease Magprol CR tablet is unsafe to use in people with liver diseases. Consult your doctor before using them. CardiovascularKidney impairment People with kidney impairment should use Magprol CR tablets cautiously. Dose adjustments may be necessary, so discussing any kidney-related issues with their doctor is essential. PregnancyPregnant and breastfeeding women Magprol is unsafe during pregnancy due to the potential risks to the fetus. Effective contraception is advised for women of childbearing age while on this medication. If breastfeeding, consult your doctor, as the drug may pass into breast milk and pose risks to the infant. wineAvoid Avoid Magprol if you are allergic to its active ingredient. Furthermore, avoid consuming alcohol with Magprol, as there is less information available regarding the safety of consuming them together. Moreover, avoid driving or operating machinery, as Magprol may lead to decreased alertness.

Tropind Plus is a combination ophthalmic solution containing Tropicamide 0.8% and Phenylephrine 5%. This formulation is primarily used for both diagnostic and therapeutic purposes in ophthalmology. 🩺 Primary Uses of Tropind Plus 1. Pupillary Dilation (Mydriasis): The combination of Tropicamide and Phenylephrine effectively dilates the pupil, allowing eye care professionals to conduct thorough examinations of the retina, optic nerve, and other internal structures. 2. Cycloplegia: Tropicamide paralyzes the ciliary muscle, preventing accommodation (focusing), which is useful in refractive error assessments. 3. Uveitis Management: In cases of uveitis, Tropind Plus helps alleviate pain and prevents further spasms of the eye muscles. 4. Preoperative Preparation: Before surgeries like cataract extraction or retinal procedures, dilating the pupil is essential for clear visualization of the posterior segment. 5. Retinal Imaging: Facilitates procedures such as fundus photography and optical coherence tomography (OCT) by ensuring adequate pupil dilation. ⚙️ How It Works • Tropicamide is a parasympatholytic agent that inhibits the contraction of the circular muscle and paralyzes the ciliary muscle, leading to pupil dilation and cycloplegia. Phenylephrine is a sympathomimetic drug that causes contraction of the radial muscle of the iris, contributing to pupil dilation. Together, these agents produce rapid and effective dilation of the pupil, facilitating detailed eye examinations and procedures. ⚠️ Side Effects Common side effects may include: • Eye pain or stinging • Blurred vision • Sensitivity to light (photophobia) • Allergic reactions These effects are typically temporary and resolve shortly after the examination. 🧪 Safety and Precautions • Driving and Operating Machinery: Avoid activities that require clear vision, such as driving, immediately after application, as the solution can cause temporary blurred vision. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or while breastfeeding, as safety data may be limited. • Drug Interactions: Be cautious when using Tropind Plus with certain medications, especially monoamine oxidase inhibitors (MAOIs) or tricyclic antidepressants, as interactions may occur.

Paripher Eye Drop is a pharmaceutical product containing Phenylephrine Hydrochloride 5%. It is primarily used in ophthalmology for various diagnostic and therapeutic purposes. ________________________________________ 🔍 Uses of Paripher Eye Drop 1. Pupil Dilation (Mydriasis): Paripher is commonly employed to dilate the pupil during eye examinations and surgical procedures, facilitating a clearer view of the retina and other internal structures. 2. Treatment of Eye Redness and Irritation: As a decongestant, it constricts blood vessels in the eye, reducing redness and irritation caused by allergies or other factors. 3. Management of Uveitis: Phenylephrine's vasoconstrictive properties aid in managing inflammation associated with uveitis by decreasing blood flow to the affected area. 4. Adjunct in Nasal Decongestion: Though primarily an eye drop, Paripher's active ingredient is also utilized in nasal decongestants to relieve symptoms of the common cold. ________________________________________ ⚠️ Usage Instructions • Application: Instill the prescribed number of drops into the lower conjunctival sac of the eye. • Contact Lenses: Remove soft contact lenses before application and wait at least 10–15 minutes before reinsertion. • Avoid Contamination: Do not touch the dropper tip to any surface, including the eye, to prevent contamination. • Multiple Medications: If using other eye medications, wait at least 10 minutes before applying them to avoid dilution. ________________________________________ ⚠️ Safety and Side Effects • Common Side Effects: Temporary eye discomfort, such as stinging or burning sensations. • Serious Side Effects: Although rare, systemic absorption may lead to increased blood pressure, headache, or dizziness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding.

Pipracan 4.5 Injection is a combination antibiotic medication containing Piperacillin (4 g) and Tazobactam (0.5 g). This formulation is used to treat a wide range of serious bacterial infections that may not respond to other antibiotics. ________________________________________ 🔹 Common Uses Pipracan 4.5 Injection is prescribed for: • Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) • Urinary tract infections (UTIs) • Intra-abdominal infections (e.g., peritonitis) • Skin and soft tissue infections, including diabetic foot infections • Gynecological infections, such as uterine infections • Bone and joint infections • Bloodstream infections (bacteremia) It is also used for prophylactic treatment in surgical procedures to prevent infections. ________________________________________ 🔹 How It Works • Piperacillin is a broad-spectrum penicillin antibiotic that inhibits bacterial cell wall synthesis, leading to bacterial cell death. • Tazobactam is a beta-lactamase inhibitor that protects piperacillin from degradation by beta-lactamase enzymes produced by certain bacteria, thereby enhancing its efficacy. This combination allows Pipracan 4.5 to target a wide array of bacteria, including those resistant to other antibiotics. ________________________________________ 🔹 Administration Pipracan 4.5 Injection is administered intravenously by a healthcare professional. The dosage and duration of treatment depend on the type and severity of the infection, as well as the patient's medical condition. Self-administration is not recommended. ________________________________________ 🔹 Side Effects Common side effects may include: • Nausea or vomiting • Diarrhea • Rash or itching • Pain, redness, or swelling at the injection site Serious side effects are rare but can include allergic reactions, liver enzyme abnormalities, or blood disorders. Seek immediate medical attention if you experience symptoms like difficulty breathing, swelling of the face or throat, or unusual bruising or bleeding. ________________________________________ 🔹 Precautions Before using Pipracan 4.5 Injection, inform your doctor if you have: Allergies to penicillins or beta-lactam antibiotics • Kidney or liver disease • A history of gastrointestinal diseases, such as colitis • Bleeding disorders • Undergoing dialysisUse during pregnancy and breastfeeding should be discussed with your healthcare provider. The medication should only be used if the potential benefits justify the potential risks.

Actorise 100 Injection is used in the treatment of anemia that may have occurred due to chronic kidney disease or chemotherapy. It works by stimulating the bone marrow to produce more red blood cells. Actorise 100 Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects. It is important that you seek treatment from a doctor who is experienced in providing this medical therapy. You should follow all the directions of the doctor strictly. It is given under the supervision of a healthcare professional. It may cause side effects like high blood pressure and hypersensitivity. Inform your doctor if there are symptoms of very high blood pressure such as severe headache, problems with your eyesight, nausea, vomiting, or fits (seizures). Your doctor may get your blood tests done regularly to monitor the levels of salts (electrolytes such as potassium), hemoglobin, and blood cells in your blood. You should stop taking it and consult with a doctor if you develop shortness of breath or skin rash.

Actorise 200 Injection is used in the treatment of anemia that may have occurred due to chronic kidney disease or chemotherapy. It works by stimulating the bone marrow to produce more red blood cells. Actorise 200 Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects. It is important that you seek treatment from a doctor who is experienced in providing this medical therapy. You should follow all the directions of the doctor strictly. It is given under the supervision of a healthcare professional. It may cause side effects like high blood pressure and hypersensitivity. Inform your doctor if there are symptoms of very high blood pressure such as severe headache, problems with your eyesight, nausea, vomiting, or fits (seizures).