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'betalactamase inhibitor'

Items tagged with 'betalactamase inhibitor'

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Cats and Dogs

Carodyl contains the most widely used non-steroidal anti-inflammatory drug – Carprofen. Carprofen works by inhibiting an enzyme called cyclooxygenase (COX). This results in lower production of a substance called prostaglandins. By reducing prostaglandin levels, carprofen helps to control pain. Carprofen is a preferential COX 2 inhibitor, with higher ratio of COX 2 to COX 1 inhibition. This is associated with good pain control (analgesic property) with minimal risk of side effects associated with COX 1 inhibition (minimal risk of bleeding). Carodyl Is indicated for the relief of pain and inflammation associated with osteoarthritis and for the control of post-operative pain associated with soft tissue and orthopedic surgeries in dogs.

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Cats and Dogs

Aceptor contains Benazepril hydrochloride, an Angiotensin Converting Enzyme (ACE)-inhibitor. ACE inhibitors block an enzyme called Angiotensin Converting Enzyme (ACE) and helps in relaxing (dilatation) of blood vessels, thereby reducing blood pressure. Aceptor increases survival of patients with Dilated Cardiomyopathy (DCM) and Mitral valve disease (MMVD). It also reduces protein loss associated with Chronic Kidney Disease (CKD), decreases left ventricular wall thickness in Hypertrophic Cardiomyopathy (HCM) in cats and helps in the treatment of hypertension.

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Eye Care

Tropind Plus is a combination ophthalmic solution containing Tropicamide 0.8% and Phenylephrine 5%. This formulation is primarily used for both diagnostic and therapeutic purposes in ophthalmology. 🩺 Primary Uses of Tropind Plus 1. Pupillary Dilation (Mydriasis): The combination of Tropicamide and Phenylephrine effectively dilates the pupil, allowing eye care professionals to conduct thorough examinations of the retina, optic nerve, and other internal structures. 2. Cycloplegia: Tropicamide paralyzes the ciliary muscle, preventing accommodation (focusing), which is useful in refractive error assessments. 3. Uveitis Management: In cases of uveitis, Tropind Plus helps alleviate pain and prevents further spasms of the eye muscles. 4. Preoperative Preparation: Before surgeries like cataract extraction or retinal procedures, dilating the pupil is essential for clear visualization of the posterior segment. 5. Retinal Imaging: Facilitates procedures such as fundus photography and optical coherence tomography (OCT) by ensuring adequate pupil dilation. ⚙️ How It Works • Tropicamide is a parasympatholytic agent that inhibits the contraction of the circular muscle and paralyzes the ciliary muscle, leading to pupil dilation and cycloplegia. Phenylephrine is a sympathomimetic drug that causes contraction of the radial muscle of the iris, contributing to pupil dilation. Together, these agents produce rapid and effective dilation of the pupil, facilitating detailed eye examinations and procedures. ⚠️ Side Effects Common side effects may include: • Eye pain or stinging • Blurred vision • Sensitivity to light (photophobia) • Allergic reactions These effects are typically temporary and resolve shortly after the examination. 🧪 Safety and Precautions • Driving and Operating Machinery: Avoid activities that require clear vision, such as driving, immediately after application, as the solution can cause temporary blurred vision. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or while breastfeeding, as safety data may be limited. • Drug Interactions: Be cautious when using Tropind Plus with certain medications, especially monoamine oxidase inhibitors (MAOIs) or tricyclic antidepressants, as interactions may occur.

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General Medicine

Pipracan 4.5 Injection is a combination antibiotic medication containing Piperacillin (4 g) and Tazobactam (0.5 g). This formulation is used to treat a wide range of serious bacterial infections that may not respond to other antibiotics. ________________________________________ 🔹 Common Uses Pipracan 4.5 Injection is prescribed for: • Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) • Urinary tract infections (UTIs) • Intra-abdominal infections (e.g., peritonitis) • Skin and soft tissue infections, including diabetic foot infections • Gynecological infections, such as uterine infections • Bone and joint infections • Bloodstream infections (bacteremia) It is also used for prophylactic treatment in surgical procedures to prevent infections. ________________________________________ 🔹 How It Works • Piperacillin is a broad-spectrum penicillin antibiotic that inhibits bacterial cell wall synthesis, leading to bacterial cell death. • Tazobactam is a beta-lactamase inhibitor that protects piperacillin from degradation by beta-lactamase enzymes produced by certain bacteria, thereby enhancing its efficacy. This combination allows Pipracan 4.5 to target a wide array of bacteria, including those resistant to other antibiotics. ________________________________________ 🔹 Administration Pipracan 4.5 Injection is administered intravenously by a healthcare professional. The dosage and duration of treatment depend on the type and severity of the infection, as well as the patient's medical condition. Self-administration is not recommended. ________________________________________ 🔹 Side Effects Common side effects may include: • Nausea or vomiting • Diarrhea • Rash or itching • Pain, redness, or swelling at the injection site Serious side effects are rare but can include allergic reactions, liver enzyme abnormalities, or blood disorders. Seek immediate medical attention if you experience symptoms like difficulty breathing, swelling of the face or throat, or unusual bruising or bleeding. ________________________________________ 🔹 Precautions Before using Pipracan 4.5 Injection, inform your doctor if you have: Allergies to penicillins or beta-lactam antibiotics • Kidney or liver disease • A history of gastrointestinal diseases, such as colitis • Bleeding disorders • Undergoing dialysisUse during pregnancy and breastfeeding should be discussed with your healthcare provider. The medication should only be used if the potential benefits justify the potential risks.

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General Medicine

Omeecan 40 is a brand of Omeprazole 40 mg Injection, manufactured by American Remedies. Omeprazole is a proton pump inhibitor (PPI) that reduces stomach acid production. The injection form is typically used in hospital settings when oral administration is not feasible. ________________________________________ ✅ Primary Uses Omeecan 40 Injection is indicated for: • Gastroesophageal Reflux Disease (GERD): To treat and manage acid reflux symptoms. • Peptic Ulcers: Including gastric and duodenal ulcers, to promote healing and alleviate symptoms. • Stress Ulcers: To prevent and treat ulcers in critically ill patients. • Zollinger-Ellison Syndrome: A condition characterized by excessive stomach acid production. • Helicobacter pylori Eradication: As part of combination therapy to eliminate H. pylori infection, which can cause ulcers. ________________________________________ ⚙️ Mechanism of Action Omeprazole works by irreversibly inhibiting the proton pump (H+/K+ ATPase enzyme) in the stomach lining, thereby reducing gastric acid secretion. This leads to increased gastric pH, promoting healing of acid-related conditions. ________________________________________ ⚠️ Precautions • Allergy: Do not use if allergic to omeprazole or other PPIs. • Drug Interactions: May interact with medications like clopidogrel, warfarin, and certain HIV medications. • Kidney and Liver Function: Use with caution in patients with impaired kidney or liver function. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. ________________________________________ 💊 Side Effects Common Side Effects: • Headache • Nausea

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General Medicine

Nezolid 600 Injection is a brand of Linezolid Injection 600 mg/300 mL, manufactured by American Remedies. Linezolid is an antibiotic belonging to the oxazolidinone class, effective against various serious bacterial infections. ________________________________________ ✅ Primary Uses Nezolid 600 Injection is indicated for the treatment of: • Nosocomial Pneumonia: Hospital-acquired pneumonia caused by susceptible strains of bacteria. • Community-Acquired Pneumonia (CAP): Pneumonia acquired outside of healthcare settings. • Complicated Skin and Skin Structure Infections (cSSSIs): Infections involving deeper layers of the skin and underlying tissues. • Vancomycin-Resistant Enterococcus faecium (VRE) Infections: Including cases with concurrent bacteremia. These infections are typically caused by Gram-positive bacteria, including multidrug-resistant strains. ________________________________________ ⚙️ Mechanism of Action Linezolid works by inhibiting bacterial protein synthesis. It binds to the bacterial ribosome, preventing the formation of the initiation complex necessary for protein production, thereby halting bacterial growth. This bacteriostatic action is particularly effective against Gram-positive organisms. ________________________________________ ⚠️ Precautions • Drug Interactions: Avoid concurrent use with monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants (TCAs), and certain other medications due to the risk of serotonin syndrome. • Pre-existing Conditions: Use with caution in patients with a history of seizures, diabetes mellitus, liver cirrhosis, or renal impairment. • Dietary Restrictions: Limit intake of foods high in tyramine (e.g., aged cheeses, cured meats, soy products) to reduce the risk of hypertensive reactions. • Pregnancy and Lactation: Consult a healthcare provider before use during pregnancy or breastfeeding.

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General Medicine

Milrican 10 is a brand of Milrinone Lactate Injection, manufactured by American Remedies. Milrinone is a phosphodiesterase-3 (PDE3) inhibitor that serves as both an inotropic agent and a vasodilator. ________________________________________ ✅ Primary Uses of Milrican 10 Milrican 10 is indicated for the short-term intravenous treatment of: • Severe congestive heart failure: Particularly in patients unresponsive to conventional therapies. • Acute decompensated heart failure: Including low output states following cardiac surgery. It is commonly used in intensive care units or during cardiac procedures to support heart function. ________________________________________ ⚙️ Mechanism of Action Milrinone works by inhibiting PDE3, leading to increased cyclic AMP (cAMP) levels in cardiac and vascular smooth muscle cells. This results in: • Increased myocardial contractility: Enhancing the heart's ability to pump blood. • Vasodilation: Relaxing blood vessels, which reduces the heart's workload and improves blood flow. ________________________________________ ⚠️ Important Considerations • Administration: Milrican 10 should only be administered intravenously under the supervision of a healthcare professional. • Monitoring: Patients receiving Milrican 10 require close monitoring of blood pressure, heart rate, and kidney function. • Contraindications: Not recommended for patients with severe dehydration, electrolyte imbalances, or known hypersensitivity to milrinone. • Pregnancy and Breastfeeding: Consult a doctor before use if pregnant or breastfeeding.

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General Medicine

Esomecan 40mg Injection is a medicine that reduces the amount of acid produced in your stomach. It is used for treating acid-related diseases of the stomach and intestine such as acid reflux and some other stomach conditions associated with excessive acid production. Esomecan 40mg Injection is also used to prevent stress ulcers in seriously ill patients and is administered before anesthetic medication to help prevent aspiration-related complications. It belongs to a class of medicines known as proton pump inhibitors (PPIs). This medicine is administered into a vein by a healthcare professional and will only be given to you if your doctor thinks that an injection is more suitable for you at the moment than a tablet. The dose will depend on your underlying condition and how you respond to the medicine. Additionally, your doctor will decide the duration of treatment. You can increase the efficiency of the treatment by eating smaller meals more often and avoiding caffeinated drinks (like tea and coffee), and spicy or fatty foods. The most common side effects observed with this medicine include injection site reactions, nausea, headache, dizziness, flatulence, diarrhea, stomach pain, and fundic gland polyps. These symptoms are generally mild but if they bother you or do not go away, consult your doctor. Talk to your doctor about ways to prevent bone loss (osteoporosis), like taking calcium and vitamin D supplements.

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Immunoglobulins

Tacrocord 0.5mg Capsule contains the active substance Tacrolimus. It is an immunosuppressant that belongs to the class of medications called calcineurin inhibitors. This capsule is used along with other medications to prevent organ transplant rejection in people receiving liver, kidney, heart, or other transplants. It is also indicated to control your body’s immune response, enabling it to accept the transplanted organ. Do not take this Tacrocord 0.5mg Capsule if you are allergic to tacrolimus or any of the other ingredients of this medicine. Report your physician if you are allergic to any antibiotic group. Inform your doctor if you have or had a liver or heart disease before initiating the treatment. Notify your physician immediately if you develop fever, bruising under the skin (which may appear as red dots), unexplained tiredness, confusion, yellowing of the skin or eyes, reduced urine output, vision loss, and seizures after taking this medicine. Limit exposure to sunlight and UV light while consuming Tacrocord 0.5mg Capsule by wearing appropriate protective clothing and sunscreen with a high sun protection factor. This is because of the potential risk of malignant skin changes with immunosuppressive therapy. This medicine may cause diarrhea; inform your physician if you have diarrhea for over a day. If you need to receive any vaccinations, consult your doctor once before receiving them.

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