INTRODUCTION ABOUT RITUXIREL 100 INJECTION RITUXIREL 100 INJECTION contains Rituximab which belongs to the group of medicines called Anticancer drugs. It is used to manage blood cancer (leukaemia) and lymph cancer (lymphoma). It can also be used to manage various auto-immune disease conditions such as rheumatoid arthritis, granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels) and pemphigus vulgaris (severe skin blistering and peeling especially on the mouth, nose, throat, eyes and genitals). It is mostly used in combination with other cytotoxic anticancer agents to achieve better results. It is suitable for use both in adults and in children (aged 6 months or older). RITUXIREL 100 INJECTION will be administered to you only by an oncologist or a trained professional into your vein (as intravenous infusion). Before receiving RITUXIREL 100 INJECTION inform your doctor if you have any heart problems (such as chest pain, heart attack, heart failure or abnormal heartbeat). You must also inform your doctor if you currently have or previously had hepatitis B infection or any other mild infections (including minor cough and cold) as a precaution. RITUXIREL 100 INJECTION is not recommended for use in pregnant or breastfeeding women. Both men and women receiving RITUXIREL 100 INJECTION must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with RITUXIREL 100 INJECTION. The most common side effects of receiving this medicine are fever, chills, skin rashes with itching, shortness of breath and low blood pressure. Consult your doctor if any of these side effect worsens. USES OF RITUXIREL 100 INJECTION It is used to manage: Blood cancer (Chronic lymphocytic leukaemia) Lymph cancer (Non-Hodgkin’s Lymphoma) Rheumatoid arthritis (joint pain and inflammation) Granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels) Pemphigus vulgaris (severe skin blistering and peeling especially on the mouth, nose, throat, eyes and genitals) HOW RITUXIREL 100 INJECTION WORKS RITUXIREL 100 INJECTION is a monoclonal antibody. It destroys the immune cells (B-cells) that triggers cancer formation. It also reduces the production of certain chemicals within the body (such as rheumatoid factor, T-cells, cytokines) that causes inflammation, pain and swelling which helps in managing various autoimmune diseases. DIRECTIONS FOR USE RITUXIREL 100 INJECTION will be given to you only by a doctor or a nurse into the vein (intravenously). Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF RITUXIREL 100 INJECTION COMMON increased infections (bacterial, viral or fungal) low RBC, WBC and platelet counts in blood nausea, vomiting, diarrhea, stomach pain, constipation, indigestion mouth ulcers hair loss fever, chills, pneumonia, shingles, cold, sinusitis thrush, urinary tract infection headache, dizziness, tiredness, weakness hepatitis B infection high blood sugar and cholesterol levels weight loss, lack of appetite numbness, tingling, pricking, burning sensation on the skin restlessness, problems in falling asleep, anxiety, depression flushing (skin redness) eye inflammation or watery eyes ringing sound in the ears, ear pain uneven or fast heart rate, high or low blood pressure shortness of breath, runny nose, nasal itching and repeated sneezing increased sweating, night sweats muscle pain, joint pain, back pain, neck pain pain while passing urine fungal foot infection (athlete’s foot) tremors (shakiness) swelling of the hands or ankles UNCOMMON blood clotting problems changes in taste slow heart rate chest tightness and lung problems RARE Contact your doctor immediately if you experience any of the following side effects: fever, chills, shivering, nausea, vomiting, skin rashes with blisters and itching, flushing, pain at the infusion site, headache, tiredness, wheezing, high blood pressure, palpitations, swelling of throat or tongue, runny or itchy nose and chest pain fever, cough, sore throat, burning pain while passing urine, feeling weak or generally unwell signs of brain problem (such as memory loss, trouble thinking, difficulty in walking or vision problems) signs of severe skin reactions (such as severe skin blistering and redness that may appear on the on the mucous membranes, such as inside the mouth, the genital areas or the eyelids, with fever)

INTRODUCTION ABOUT RITUXIREL 500MG INJECTION RITUXIREL 500MG INJECTION contains Rituximab which belongs to the group of medicines called Anticancer drugs. It is used to manage blood cancer (leukaemia) and lymph cancer (lymphoma). It can also be used to manage various auto-immune disease conditions such as rheumatoid arthritis, granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels) and pemphigus vulgaris (severe skin blistering and peeling especially on the mouth, nose, throat, eyes and genitals). It is mostly used in combination with other cytotoxic anticancer agents to achieve better results. It is suitable for use both in adults and in children (aged 6 months or older). RITUXIREL 500MG INJECTION will be administered to you only by an oncologist or a trained professional into your vein (as intravenous infusion). Before receiving RITUXIREL 500MG INJECTION inform your doctor if you have any heart problems (such as chest pain, heart attack, heart failure or abnormal heartbeat). You must also inform your doctor if you currently have or previously had hepatitis B infection or any other mild infections (including minor cough and cold) as a precaution. RITUXIREL 500MG INJECTION is not recommended for use in pregnant or breastfeeding women. Both men and women receiving RITUXIREL 500MG INJECTION must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with RITUXIREL 500MG INJECTION. The most common side effects of receiving this medicine are fever, chills, skin rashes with itching, shortness of breath and low blood pressure. Consult your doctor if any of these side effect worsens. USES OF RITUXIREL 500MG INJECTION It is used to manage: Blood cancer (Chronic lymphocytic leukaemia) Lymph cancer (Non-Hodgkin’s Lymphoma) Rheumatoid arthritis (joint pain and inflammation) Granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels) Pemphigus vulgaris (severe skin blistering and peeling especially on the mouth, nose, throat, eyes and genitals) HOW RITUXIREL 500MG INJECTION WORKS RITUXIREL 500MG INJECTION is a monoclonal antibody. It destroys the immune cells (B-cells) that triggers cancer formation. It also reduces the production of certain chemicals within the body (such as rheumatoid factor, T-cells, cytokines) that causes inflammation, pain and swelling which helps in managing various autoimmune diseases. DIRECTIONS FOR USE RITUXIREL 500MG INJECTION will be given to you only by a doctor or a nurse into the vein (intravenously). Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF RITUXIREL 500MG INJECTION COMMON increased infections (bacterial, viral or fungal) low RBC, WBC and platelet counts in blood nausea, vomiting, diarrhea, stomach pain, constipation, indigestion mouth ulcers hair loss fever, chills, pneumonia, shingles, cold, sinusitis thrush, urinary tract infection headache, dizziness, tiredness, weakness hepatitis B infection high blood sugar and cholesterol levels weight loss, lack of appetite numbness, tingling, pricking, burning sensation on the skin restlessness, problems in falling asleep, anxiety, depression flushing (skin redness) eye inflammation or watery eyes ringing sound in the ears, ear pain uneven or fast heart rate, high or low blood pressure shortness of breath, runny nose, nasal itching and repeated sneezing increased sweating, night sweats muscle pain, joint pain, back pain, neck pain pain while passing urine fungal foot infection (athlete’s foot) tremors (shakiness) swelling of the hands or ankles UNCOMMON blood clotting problems changes in taste slow heart rate chest tightness and lung problems RARE Contact your doctor immediately if you experience any of the following side effects: fever, chills, shivering, nausea, vomiting, skin rashes with blisters and itching, flushing, pain at the infusion site, headache, tiredness, wheezing, high blood pressure, palpitations, swelling of throat or tongue, runny or itchy nose and chest pain fever, cough, sore throat, burning pain while passing urine, feeling weak or generally unwell signs of brain problem (such as memory loss, trouble thinking, difficulty in walking or vision problems) signs of severe skin reactions (such as severe skin blistering and redness that may appear on the on the mucous membranes, such as inside the mouth, the genital areas or the eyelids, with fever) HOW TO MANAGE SIDE EFFECTS Constipation Try to eat more high-fibre foods such as fresh fruit, vegetables, cereals, and drink plenty of water. Try doing exercise regularly (going for a daily walk or run). If this does not help, inform your doctor for receiving alternate managements for constipation.

Defstead 30 Tablet belongs to a group of medicines called steroids. It is used for the treatment of various diseases and conditions such as inflammatory conditions and autoimmune conditions. Defstead 30 Tablet works by inhibiting the release of substances that cause swelling or by changing how the immune system works. It can be taken on an empty stomach or after food. Taking the medicine regularly at the right times increases its effectiveness. It is important to keep taking the medicine regularly until your doctor tells you it is safe to stop. Use of this medicine may cause some common side effects such as increased appetite, weight gain, frequent urge to urinate, Cushing syndrome, cough, upper respiratory tract infection, abnormal hair growth, obesity, and nasopharyngitis. If any of these side effects bother you, let your doctor know.

Dexam 8mg Tablet belongs to a group of medicines called steroids. It is used in the treatment of various diseases and conditions such as inflammatory conditions, autoimmune conditions, and cancer. Dexam 8mg Tablet provides relief from swelling, redness, pain, and itching in the affected area by preventing the release of substances that cause inflammation. It should be taken with food to avoid stomach upset. Taking the medicine regularly at the right times increases its effectiveness. It is important to keep taking the medicine regularly until your doctor tells you it is safe to stop. The most common side effects of this medicine include cardiovascular complications, electrolyte imbalances, gastrointestinal disorders, metabolic disorders, musculoskeletal pain, neurological disorders, and weight gain. If you experience such symptoms that persist or get worse, let your doctor know.

Dexam 4mg Tablet belongs to a group of medicines called steroids. It is used in the treatment of various diseases and conditions such as inflammatory conditions, autoimmune conditions, and cancer. Dexam 4mg Tablet provides relief from swelling, redness, pain, and itching in the affected area by preventing the release of substances that cause inflammation. It should be taken with food to avoid stomach upset. Taking the medicine regularly at the right times increases its effectiveness. It is important to keep taking the medicine regularly until your doctor tells you it is safe to stop. The most common side effects of this medicine include cardiovascular complications, electrolyte imbalances, gastrointestinal disorders, metabolic disorders, musculoskeletal pain, neurological disorders, and weight gain. If you experience such symptoms that persist or get worse, let your doctor know.

Decmax 8mg Tablet belongs to a group of medicines called steroids. It is used in the treatment of various diseases and conditions such as inflammatory conditions, autoimmune conditions, and cancer. Decmax 8mg Tablet provides relief from swelling, redness, pain, and itching in the affected area by preventing the release of substances that cause inflammation. It should be taken with food to avoid stomach upset. Taking the medicine regularly at the right times increases its effectiveness. It is important to keep taking the medicine regularly until your doctor tells you it is safe to stop. The most common side effects of this medicine include cardiovascular complications, electrolyte imbalances, gastrointestinal disorders, metabolic disorders, musculoskeletal pain, neurological disorders, and weight gain. If you experience such symptoms that persist or get worse, let your doctor know.

Decmax 4mg Tablet belongs to a group of medicines called steroids. It is used in the treatment of various diseases and conditions such as inflammatory conditions, autoimmune conditions, and cancer. Decmax 4mg Tablet provides relief from swelling, redness, pain, and itching in the affected area by preventing the release of substances that cause inflammation. It should be taken with food to avoid stomach upset. Taking the medicine regularly at the right times increases its effectiveness. It is important to keep taking the medicine regularly until your doctor tells you it is safe to stop. The most common side effects of this medicine include cardiovascular complications, electrolyte imbalances, gastrointestinal disorders, metabolic disorders, musculoskeletal pain, neurological disorders, and weight gain. If you experience such symptoms that persist or get worse, let your doctor know.

Dexacan Injection contains Dexamethasone Sodium Phosphate, a potent corticosteroid used to manage various inflammatory, allergic, and autoimmune conditions. It is typically administered in hospital settings under medical supervision. ________________________________________ 🩺 Medical Uses Dexacan Injection is indicated for: • Adrenal Insufficiency: To replace deficient corticosteroids in conditions like Addison's disease. • Severe Allergic Reactions: Including anaphylaxis and angioedema. • Autoimmune Disorders: Such as rheumatoid arthritis, lupus, and vasculitis. • Inflammatory Conditions: Including ulcerative colitis, Crohn's disease, and certain skin disorders. • Neurological Conditions: For managing cerebral edema and certain types of meningitis. • Endocrine Disorders: As a diagnostic tool in Cushing's syndrome. • Shock Management: Particularly in cases of septic shock, often as an adjunct to other therapies. It works by suppressing inflammation and modulating the immune response. This is achieved through its glucocorticoid activity, which reduces the production of inflammatory mediators. ________________________________________ ⚙️ Dosage and Administration Dexacan Injection is administered intravenously (IV) or intramuscularly (IM) by healthcare professionals. The dosage varies based on the specific condition being treated and the patient's response. For instance, in cerebral edema, an initial IV dose of 10 mg may be followed by 4 mg IM every six hours. ________________________________________ ⚠️ Precautions and Contraindications Before using Dexacan Injection, inform your healthcare provider if you have: • Allergies to dexamethasone or other corticosteroids. • Infections, as corticosteroids can suppress the immune system. • Gastrointestinal issues, such as ulcers. • Cardiovascular diseases, including hypertension. • Diabetes, as corticosteroids can affect blood sugar levels. • Osteoporosis or other bone disorders. Use during pregnancy or breastfeeding should be discussed with a healthcare provider. ________________________________________ 💊 Side Effects Common side effects may include: • Increased appetite and weight gain. • Fluid retention and swelling. • Elevated blood pressure. • Mood swings or psychological effects. • Gastrointestinal discomfort. Long-term use can lead to more serious effects, such as osteoporosis, cataracts, and increased susceptibility to infections. ________________________________________

Dexacan Injection contains Dexamethasone Sodium Phosphate, a potent corticosteroid used to manage various inflammatory, allergic, and autoimmune conditions. It is typically administered in hospital settings under medical supervision. ________________________________________ 🩺 Medical Uses Dexacan Injection is indicated for: • Adrenal Insufficiency: To replace deficient corticosteroids in conditions like Addison's disease. • Severe Allergic Reactions: Including anaphylaxis and angioedema. • Autoimmune Disorders: Such as rheumatoid arthritis, lupus, and vasculitis. • Inflammatory Conditions: Including ulcerative colitis, Crohn's disease, and certain skin disorders. • Neurological Conditions: For managing cerebral edema and certain types of meningitis. • Endocrine Disorders: As a diagnostic tool in Cushing's syndrome. • Shock Management: Particularly in cases of septic shock, often as an adjunct to other therapies. It works by suppressing inflammation and modulating the immune response. This is achieved through its glucocorticoid activity, which reduces the production of inflammatory mediators. ________________________________________ ⚙️ Dosage and Administration Dexacan Injection is administered intravenously (IV) or intramuscularly (IM) by healthcare professionals. The dosage varies based on the specific condition being treated and the patient's response. For instance, in cerebral edema, an initial IV dose of 10 mg may be followed by 4 mg IM every six hours. ________________________________________ ⚠️ Precautions and Contraindications Before using Dexacan Injection, inform your healthcare provider if you have: • Allergies to dexamethasone or other corticosteroids. • Infections, as corticosteroids can suppress the immune system. • Gastrointestinal issues, such as ulcers. • Cardiovascular diseases, including hypertension. • Diabetes, as corticosteroids can affect blood sugar levels. • Osteoporosis or other bone disorders. Use during pregnancy or breastfeeding should be discussed with a healthcare provider. ________________________________________ 💊 Side Effects Common side effects may include: • Increased appetite and weight gain. • Fluid retention and swelling. • Elevated blood pressure. • Mood swings or psychological effects. • Gastrointestinal discomfort. Long-term use can lead to more serious effects, such as osteoporosis, cataracts, and increased susceptibility to infections. ________________________________________