MNOphyllin Injection is a brand of Aminophylline Injection, manufactured by American Remedies. Aminophylline is a bronchodilator that works by relaxing the muscles of the air passages in the lungs, making it easier to breathe. ________________________________________ ✅ Primary Uses MNOphyllin Injection is primarily used for: • Asthma: A chronic condition where the airways become inflamed and narrow, leading to difficulty in breathing. • Chronic Obstructive Pulmonary Disease (COPD): A group of lung diseases that block airflow and make breathing difficult. • Bronchospasm: A condition where the muscles around the airways tighten, leading to wheezing and shortness of breath. It is administered intravenously in a hospital setting under medical supervision. ________________________________________ ⚙️ Mechanism of Action Aminophylline works by: • Relaxing the bronchial muscles: This leads to the widening of the air passages, making it easier to breathe. • Increasing the strength of the diaphragm: This enhances the ability to breathe effectively. • Reducing airway responsiveness to irritants: This helps in decreasing inflammation and bronchoconstriction. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Medical History: Inform your doctor if you have a history of heart disease, liver or kidney disorders, or seizures. • Pregnancy and Breastfeeding: Consult your doctor before use if pregnant or breastfeeding. • Drug Interactions: Certain medications can interact with Aminophylline, so it's essential to inform your healthcare provider about all medicines you are taking. Common Side Effects: • Nausea • Vomiting • Headache • Restlessness • Dizziness Serious Side Effects: • Irregular heartbeats • Seizures • Severe allergic reactions If you experience any of these serious side effects, seek immediate medical attention.

Ondican 2 Injection is a brand of Ondansetron 2 mg/2 mL Injection, manufactured by American Remedies. Ondansetron is a 5-HT₃ receptor antagonist commonly used as an antiemetic to prevent and treat nausea and vomiting associated with various medical conditions. ________________________________________ ✅ Primary Uses Ondican 2 Injection is indicated for: • Chemotherapy-Induced Nausea and Vomiting (CINV): To prevent and treat nausea and vomiting caused by cancer chemotherapy. Radiotherapy-Induced Nausea and Vomiting (RINV): To prevent and treat nausea and vomiting associated with radiation therapy. Postoperative Nausea and Vomiting (PONV): To prevent and treat nausea and vomiting following surgical procedures. These indications are supported by clinical guidelines and pharmacological references. ________________________________________ ⚙️ Mechanism of Action Ondansetron works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting. It specifically inhibits serotonin receptors in the chemoreceptor trigger zone (CTZ) in the brain, thereby preventing the sensation of nausea and the act of vomiting. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Allergy: Do not use if allergic to ondansetron or other 5-HT₃ receptor antagonists. • Cardiac Conditions: Use with caution in patients with a history of heart problems, as ondansetron may affect heart rhythm. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Headache • Constipation • DizzinessFatigue Serious Side Effects: • Allergic reactions (rash, itching, swelling) Severe dizziness or fainting • Irregular heartbeat Seek immediate medical attention if any serious side effects occur.

Omeecan 40 is a brand of Omeprazole 40 mg Injection, manufactured by American Remedies. Omeprazole is a proton pump inhibitor (PPI) that reduces stomach acid production. The injection form is typically used in hospital settings when oral administration is not feasible. ________________________________________ ✅ Primary Uses Omeecan 40 Injection is indicated for: • Gastroesophageal Reflux Disease (GERD): To treat and manage acid reflux symptoms. • Peptic Ulcers: Including gastric and duodenal ulcers, to promote healing and alleviate symptoms. • Stress Ulcers: To prevent and treat ulcers in critically ill patients. • Zollinger-Ellison Syndrome: A condition characterized by excessive stomach acid production. • Helicobacter pylori Eradication: As part of combination therapy to eliminate H. pylori infection, which can cause ulcers. ________________________________________ ⚙️ Mechanism of Action Omeprazole works by irreversibly inhibiting the proton pump (H+/K+ ATPase enzyme) in the stomach lining, thereby reducing gastric acid secretion. This leads to increased gastric pH, promoting healing of acid-related conditions. ________________________________________ ⚠️ Precautions • Allergy: Do not use if allergic to omeprazole or other PPIs. • Drug Interactions: May interact with medications like clopidogrel, warfarin, and certain HIV medications. • Kidney and Liver Function: Use with caution in patients with impaired kidney or liver function. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. ________________________________________ 💊 Side Effects Common Side Effects: • Headache • Nausea

Nor-ADR Injection is a brand of Noradrenaline (Norepinephrine) Bitartrate Injection, manufactured by American Remedies. It is primarily used in critical care settings to manage severe hypotension (low blood pressure) and shock. ________________________________________ ✅ Primary Uses Nor-ADR Injection is indicated for: • Septic Shock: A life-threatening condition caused by severe infection leading to dangerously low blood pressure. • Cardiogenic Shock: A state where the heart is unable to pump sufficient blood to meet the body's needs. Anaphylactic Shock: A severe allergic reaction causing a sudden drop in blood pressure. • Hypotension During Surgery or Trauma: To maintain adequate blood pressure during and after surgical procedures or traumatic events. • Cardiac Arrest: As an adjunct in the management of cardiac arrest to improve blood flow to vital organs. These indications are supported by clinical guidelines and pharmacological references. ________________________________________ ⚙️ Mechanism of Action Noradrenaline is a potent vasopressor that works by: Alpha-1 Adrenergic Receptor Activation: Causing vasoconstriction, which increases systemic vascular resistance and raises blood pressure. • Beta-1 Adrenergic Receptor Activation: Increasing heart rate and myocardial contractility, thereby enhancing cardiac output. This dual action helps restore blood pressure and improve perfusion to vital organs in shock states. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Administration: Should be administered intravenously under strict medical supervision, typically in an intensive care unit (ICU) setting. • Monitoring: Continuous monitoring of blood pressure and heart rate is essential during administration. • Contraindications: Should not be used in patients with mesenteric or peripheral vascular thrombosis unless absolutely necessary. Common Side Effects: • Hypertension (high blood pressure) • Headache Nausea • Anxiety • Dizziness Serious Side Effects: • Arrhythmias (irregular heartbeats) • Tissue necrosis at the injection site • Reduced renal perfusion leading to renal failure Immediate medical attention is required if any serious side effects occur.

Nitrocan 25 Injection is a brand of Nitroglycerin Injection 25 mg/5 mL, manufactured by American Remedies. It is primarily used in hospital settings for the management of certain cardiovascular conditions. ________________________________________ ✅ Primary Uses Nitrocan 25 Injection is indicated for: • Angina Pectoris: To treat and prevent chest pain caused by reduced blood flow to the heart. • Acute Myocardial Infarction (Heart Attack): To alleviate chest pain and improve blood flow to the heart muscle. Hypertension During Surgery: To control high blood pressure during and after surgical procedures. • Congestive Heart Failure: To reduce the workload on the heart and improve symptoms. ________________________________________ ⚙️ Mechanism of Action Nitroglycerin is a nitrate that, once administered, is converted into nitric oxide in the body. This leads to the relaxation and dilation of blood vessels, improving blood flow and reducing the heart's workload. ________________________________________ ⚠️ Precautions • Contraindications: Should not be used in patients with severe anemia, hypotension, or those taking medications for erectile dysfunction (e.g., sildenafil, tadalafil) due to the risk of a significant drop in blood pressure. • Monitoring: Requires careful monitoring of blood pressure and heart rate during administration. • Administration: Administered intravenously under medical supervision; dosage and duration are determined by the healthcare provider. ________________________________________ 💊 Common Side Effects • Headache • Dizziness or lightheadedness • Hypotension (low blood pressure) • Nausea or vomiting • Flushing

Mucanix Injection is a brand of Acetylcysteine Injection, manufactured by American Remedies. Acetylcysteine is a mucolytic agent that helps in thinning and loosening mucus in the airways, making it easier to cough up and clear the airways. ________________________________________ ✅ Primary Uses Mucanix Injection is primarily used for: • Respiratory Disorders: Conditions such as chronic bronchitis, asthma, and cystic fibrosis, where there is excessive mucus production. • Paracetamol (Acetaminophen) Overdose: As an antidote to prevent liver damage when administered within 8 hours of overdose. ________________________________________ ⚙️ Mechanism of Action Acetylcysteine works by: • Breaking down mucus: It reduces the viscosity of mucus, facilitating easier expectoration. • Restoring glutathione levels: In cases of paracetamol overdose, it replenishes glutathione, a vital antioxidant, aiding in detoxification and protecting the liver. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Allergy: Do not use if allergic to acetylcysteine or any of its components. • Asthma: Use with caution in patients with asthma; monitoring is required. • Pregnancy and Breastfeeding: Consult a doctor before use during pregnancy or breastfeeding. Common Side Effects: • Nausea • Vomiting • Rash • Fever • Headache Serious Side Effects: • Anaphylactic reactions (rare) • Hypotension • Tachycardia If you experience any of these serious side effects, seek immediate medical attention.

Milrican 10 is a brand of Milrinone Lactate Injection, manufactured by American Remedies. Milrinone is a phosphodiesterase-3 (PDE3) inhibitor that serves as both an inotropic agent and a vasodilator. ________________________________________ ✅ Primary Uses of Milrican 10 Milrican 10 is indicated for the short-term intravenous treatment of: • Severe congestive heart failure: Particularly in patients unresponsive to conventional therapies. • Acute decompensated heart failure: Including low output states following cardiac surgery. It is commonly used in intensive care units or during cardiac procedures to support heart function. ________________________________________ ⚙️ Mechanism of Action Milrinone works by inhibiting PDE3, leading to increased cyclic AMP (cAMP) levels in cardiac and vascular smooth muscle cells. This results in: • Increased myocardial contractility: Enhancing the heart's ability to pump blood. • Vasodilation: Relaxing blood vessels, which reduces the heart's workload and improves blood flow. ________________________________________ ⚠️ Important Considerations • Administration: Milrican 10 should only be administered intravenously under the supervision of a healthcare professional. • Monitoring: Patients receiving Milrican 10 require close monitoring of blood pressure, heart rate, and kidney function. • Contraindications: Not recommended for patients with severe dehydration, electrolyte imbalances, or known hypersensitivity to milrinone. • Pregnancy and Breastfeeding: Consult a doctor before use if pregnant or breastfeeding.

Colistican 3 Injection is an intravenous formulation containing Colistimethate Sodium 3 Million IU, manufactured by American Remedies. It is primarily used to treat severe infections caused by multidrug-resistant Gram-negative bacteria. ________________________________________ 🩺 Uses of Colistican 3 Injection Colistican 3 Injection is indicated for: • Ventilator-Associated Pneumonia (VAP): A lung infection acquired during mechanical ventilation. • Bloodstream Infections (Sepsis): Infections caused by resistant bacteria entering the bloodstream. • Urinary Tract Infections (UTIs): Caused by multidrug-resistant Gram-negative organisms. • Intra-abdominal Infections: Such as peritonitis. • Cystic Fibrosis: For chronic pulmonary infections due to Pseudomonas aeruginosa in both adults and children. ________________________________________ 💊 Mechanism of Action Colistimethate sodium is a prodrug that, upon administration, is converted to colistin. Colistin binds to the bacterial cell membrane, disrupting its structure and leading to cell death. It is particularly effective against aerobic Gram-negative bacteria with hydrophobic outer membranes. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Renal Function: Use with caution in patients with kidney impairment. • Neurological Effects: Monitor for signs of neurotoxicity, including dizziness and muscle weakness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Injection site reactions • Renal toxicity • Neurological symptoms (e.g., confusion, dizziness) • Gastrointestinal disturbances (e.g., nausea, vomiting) • Muscle weakness

Colistican 2 Injection is a brand of Colistimethate Sodium for Injection, manufactured by American Remedies. It is a polymyxin-class antibiotic used to treat serious infections caused by multidrug-resistant Gram-negative bacteria. ________________________________________ 🩺 Uses of Colistican 2 Injection Colistican 2 Injection is primarily indicated for: • Ventilator-Associated Pneumonia (VAP): A lung infection acquired during mechanical ventilation. • Bacteremia (Bloodstream Infection): Infections caused by resistant bacteria entering the bloodstream. • Lower Respiratory Tract Infections: Including severe cases of pneumonia and bronchitis. • Urinary Tract Infections (UTIs): Caused by multidrug-resistant Gram-negative organisms. These infections are typically caused by pathogens such as Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae, which are resistant to multiple antibiotics. ________________________________________ 💊 Mechanism of Action Colistimethate sodium is a prodrug that, upon administration, is converted to colistin. Colistin binds to the bacterial cell membrane, disrupting its structure and leading to cell death. It is particularly effective against aerobic Gram-negative bacteria with hydrophobic outer membranes. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Renal Function: Use with caution in patients with kidney impairment. • Neurological Effects: Monitor for signs of neurotoxicity, including dizziness and muscle weakness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Injection site reactions • Renal toxicity • Neurological symptoms (e.g., confusion, dizziness) • Gastrointestinal disturbances (e.g., nausea, vomiting) • Muscle weakness