'treatments fail hypotension'

Nor-ADR Injection is a brand of Noradrenaline (Norepinephrine) Bitartrate Injection, manufactured by American Remedies. It is primarily used in critical care settings to manage severe hypotension (low blood pressure) and shock. ________________________________________ ✅ Primary Uses Nor-ADR Injection is indicated for: • Septic Shock: A life-threatening condition caused by severe infection leading to dangerously low blood pressure. • Cardiogenic Shock: A state where the heart is unable to pump sufficient blood to meet the body's needs. Anaphylactic Shock: A severe allergic reaction causing a sudden drop in blood pressure. • Hypotension During Surgery or Trauma: To maintain adequate blood pressure during and after surgical procedures or traumatic events. • Cardiac Arrest: As an adjunct in the management of cardiac arrest to improve blood flow to vital organs. These indications are supported by clinical guidelines and pharmacological references. ________________________________________ ⚙️ Mechanism of Action Noradrenaline is a potent vasopressor that works by: Alpha-1 Adrenergic Receptor Activation: Causing vasoconstriction, which increases systemic vascular resistance and raises blood pressure. • Beta-1 Adrenergic Receptor Activation: Increasing heart rate and myocardial contractility, thereby enhancing cardiac output. This dual action helps restore blood pressure and improve perfusion to vital organs in shock states. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Administration: Should be administered intravenously under strict medical supervision, typically in an intensive care unit (ICU) setting. • Monitoring: Continuous monitoring of blood pressure and heart rate is essential during administration. • Contraindications: Should not be used in patients with mesenteric or peripheral vascular thrombosis unless absolutely necessary. Common Side Effects: • Hypertension (high blood pressure) • Headache Nausea • Anxiety • Dizziness Serious Side Effects: • Arrhythmias (irregular heartbeats) • Tissue necrosis at the injection site • Reduced renal perfusion leading to renal failure Immediate medical attention is required if any serious side effects occur.

Nitrocan 25 Injection is a brand of Nitroglycerin Injection 25 mg/5 mL, manufactured by American Remedies. It is primarily used in hospital settings for the management of certain cardiovascular conditions. ________________________________________ ✅ Primary Uses Nitrocan 25 Injection is indicated for: • Angina Pectoris: To treat and prevent chest pain caused by reduced blood flow to the heart. • Acute Myocardial Infarction (Heart Attack): To alleviate chest pain and improve blood flow to the heart muscle. Hypertension During Surgery: To control high blood pressure during and after surgical procedures. • Congestive Heart Failure: To reduce the workload on the heart and improve symptoms. ________________________________________ ⚙️ Mechanism of Action Nitroglycerin is a nitrate that, once administered, is converted into nitric oxide in the body. This leads to the relaxation and dilation of blood vessels, improving blood flow and reducing the heart's workload. ________________________________________ ⚠️ Precautions • Contraindications: Should not be used in patients with severe anemia, hypotension, or those taking medications for erectile dysfunction (e.g., sildenafil, tadalafil) due to the risk of a significant drop in blood pressure. • Monitoring: Requires careful monitoring of blood pressure and heart rate during administration. • Administration: Administered intravenously under medical supervision; dosage and duration are determined by the healthcare provider. ________________________________________ 💊 Common Side Effects • Headache • Dizziness or lightheadedness • Hypotension (low blood pressure) • Nausea or vomiting • Flushing

Furopad 300MG/30ml Syrup Salt: Furosemide (10mg/ml) Description Furoped Oral Solution Pineapple belongs to a group of medicines called diuretics or water tablets. It is used to reduce the swelling (edema) caused by too much water in the body in people who have heart failure, liver or kidney disease. This medicine is also used to treat high blood pressure. Furoped Oral Solution Pineapple belongs to a group of medicines called diuretics or water tablets. It is used to reduce the swelling (edema) caused by too much water in the body in people who have heart failure, liver or kidney disease. This medicine is also used to treat high blood pressure. Furoped Oral Solution Pineapple helps your body get rid of extra water and salt through urine. It may be used alone or in combination with other medicines as per the dose advised by your doctor. It can be taken with or without food and should be taken at the same time each day. It is best to avoid taking this medicine within 4 hours of your bedtime to prevent having to get up at night to urinate. It is important to continue taking this medication even if you feel well. If you stop taking it without consulting your doctor, your condition may worsen. Lifestyle changes like reducing stress, restricting salt intake, and stopping smoking may help this medication work better. Common side effects of this medicine include hypotension, electrolyte imbalance, dehydration, decreased sodium level in blood, decreased potassium level in the blood, and decreased magnesium level in blood. These are usually mild and disappear after a short time. Consult your doctor if they bother you or do not go away. Before taking this medicine, let your doctor know if you have any liver problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Regular monitoring of kidney function tests and electrolyte levels is important while using this medicine. It may reduce the potassium level in your blood so your doctor may ask you to add potassium-rich foods to your diet (such as bananas, coconut water, etc.) or prescribe supplements. Benefits 1. In Treatment of Hypertension (high blood pressure): Furoped Oral Solution Pineapple prevents your body from absorbing too much salt and allows the salt to be removed in your urine instead. It also helps get rid of excess water. This helps to lower your blood pressure and makes it easier for your heart to pump blood around your body. When your blood pressure is lower, you are less at risk of having a heart attack or a stroke. You should make appropriate lifestyle changes to help this medicine be effective and you need to take it regularly. 2. In Treatment of Edema: Furoped Oral Solution Pineapple works by increasing the amount of urine produced. This helps your body get rid of extra water thereby relieving symptoms such as shortness of breath and swelling in your arms, legs, or abdomen. This will help you go about your daily activities more easily and make you more confident about being active. Take it regularly and make appropriate lifestyle changes to help this medicine be effective. Side Effects Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Common side effects of Furoped: - Dehydration - Decreased potassium level in blood - Decreased magnesium level in blood - Decreased blood pressure - Electrolyte imbalance - Decreased sodium level in blood

Milicor 10mg Injection Marketer Samarth Life Sciences Pvt Ltd SALT COMPOSITION Milrinone (10mg) Storage Store below 30°C Uses of Milicor Injection Heart Failure Product introduction Milicor 10mg Injection is a medicine used for short-term treatment of heart failure. It is also used to treat patients with a poorly functioning heart after heart surgery. It makes the heart pump blood more efficiently. It is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. The doctor may closely monitor your blood pressure, heart rate, and ECG until you become stable. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection. Common side effects of this medicine include hypotension, headaches, arrhythmias, and tachycardia. Consult your doctor if these effects bother you. This medicine is used with caution for some people. Thus, you must inform the doctor if you are suffering from any kidney disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly. Side effects of Milicor Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Milicor Hypotension (low blood pressure) Headache Arrhythmia (irregular heartbeats) Tachycardia How to use Milicor Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Milicor Injection works Milicor 10mg Injection is a vasodilator. It increases the level of a chemical messenger (cAMP), which helps the smooth muscles to relax. Thus, dilates the blood vessels for better blood flow into the heart. It also has blood thinning property. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Milicor 10mg Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Milicor 10mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. warnings Breast feeding SAFE IF PRESCRIBED Milicor 10mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. warnings Driving CONSULT YOUR DOCTOR It is not known whether Milicor 10mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. warnings Kidney CAUTION Milicor 10mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Milicor 10mg Injection may be needed. Please consult your doctor. warnings Liver SAFE IF PRESCRIBED Milicor 10mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Milicor 10mg Injection may not be needed in these patients. Please consult your doctor.

Nipress 50mg Injection Marketer Samarth Life Sciences Pvt Ltd SALT COMPOSITION Nitroprusside (50mg) Storage Store below 30°C Uses of Nipress Injection Angina (heart-related chest pain) Heart Failure Coronary artery disease Hypertensive emergency Anal fissure Product introduction Nipress 50mg Injection is a medicine used in the immediate treatment of hypertensive emergency (severely increased blood pressure) and acute heart failure. It brings about an immediate reduction in blood pressure and the workload of the heart. Nipress 50mg Injection is given as a drip into the vein under the supervision of a doctor. Your doctor is the right person to decide the dose and duration, hence do not try to self-administered the injection at home. Regular monitoring of blood pressure is required while on treatment. Decreased blood pressure (hypotension) may occur as a side effect of this medicine. Inform your doctor if you are pregnant, planning to conceive or breastfeeding. It is also advisable to avoid medication like sildenafil or tadalafil while on treatment as it may cause a sudden lowering of blood pressure. Side effects of Nipress Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Nipress Cyanide poisoning Decreased blood pressure How to use Nipress Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Nipress Injection works Nipress 50mg Injection is a vasodilator. It works by relaxing the muscles in your blood vessels to help them widen and results in the lowering of blood pressure. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Nipress 50mg Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Nipress 50mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. warnings Breast feeding CONSULT YOUR DOCTOR Nipress 50mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. warnings Driving CONSULT YOUR DOCTOR It is not known whether Nipress 50mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. warnings Kidney SAFE IF PRESCRIBED Nipress 50mg Injection is safe to use in patients with kidney disease. No dose adjustment of Nipress 50mg Injection is recommended. However, talk to your doctor if you have any underlying kidney disease.

Dopan 200mg Injection Salt Composition : Dopamine Hydrochloride Manufacturer : CELON LABORATORIES LTD Introduction to Dopan 200mg Injection Dopan 200mg injection contains the active ingredient Dopamine hydrochloride. It is used to treat low blood pressure and helps improve the muscle contraction strength in the heart. It also aids in improving low blood pressure due to open heart surgery, injury, congestive heart failure, heart attack, blood poisoning, and infection. Inform your doctor before using Dopan 200mg injection if you are pregnant or breastfeeding, if you have heart problems, liver or kidney problems, sulphite sensitivity, a tumor, narrow-angle glaucoma, diabetes, blood disorder, hyperthyroidism, or if you have been taking antidepressants. Headache, nausea and vomiting, palpitation, trouble breathing (dyspnoea), low blood pressure, and chest pain are common side effects seen with the use of Dopan 200mg injection. Uses of Dopan 200mg Injection In treating low blood pressure or shock due to heart attack, trauma, or injury In treating low blood pressure due to blood infections or blood poisoning To treat congestive heart failure In combination with other treatments to treat low blood pressure after open heart surgery. Therapeutic Effects of Dopan 200mg Injection Dopan 200mg injection works by producing an ionotropic effect on the muscles of the heart, which causes an increase in the strength of heart muscle contractions and heart rate. As a result of this, there is an increase in blood pressure and cardiac output. Interaction of Dopan 200mg Injection with other drugs Inform your healthcare professional about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications belong to Tricyclic antidepressant drugs, and interacting with Dopan 200mg injection may reduce effectiveness by causing undesirable side effects. More Information about Dopan 200mg Injection Keep Dopan 200mg injection out of the reach and sight of children. Do not store above 25°C. How to consume Dopan 200mg Injection Dopan 200mg injection is administered as an intravenous infusion into the vein. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person. Safety Advices for Dopan 200mg Injection Image Not Available Pregnancy If you are planning a pregnancy or think you may be pregnant, inform your doctor. Dopan 200mg injection might be unsafe during pregnancy because it can harm the unborn baby. Image Not Available Breast Feeding Inform your doctor in case you are breastfeeding since it is unknow whether Dopan 200mg injection is good for breast milk or not. Image Not Available Lungs It is unknown whether Dopan 200mg injection is safe for lung conditions. So consult your doctor in case you have any lung disease before starting the treatment. Image Not Available Liver Inform your doctor in case you have any liver diseases before starting treatment with Dopan 200mg injection. Image Not Available Alcohol It is unknown whether consuming alcohol while taking a Dopan 200 mg injection is safe. Please speak with your physician. Image Not Available Driving Instructions for driving are not applicable as Dopan 200mg injection is administered at the hospital. Side Effects of Dopan 200mg Injection Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Dopacan Injection is a brand of Dopamine Hydrochloride, a potent vasopressor and inotropic agent used in critical care settings to manage various cardiovascular conditions. It is administered intravenously under medical supervision. ________________________________________ 🩺 Medical Uses Dopacan Injection is indicated for: • Shock Management: Including septic shock, cardiogenic shock, and hypovolemic shock. • Acute Heart Failure: To improve cardiac output and perfusion. • Severe Hypotension: Especially in patients unresponsive to volume resuscitation. • Renal Protection: To enhance renal blood flow and urine output in certain critically ill patients. Dopamine works by stimulating dopaminergic and beta-adrenergic receptors, leading to increased heart rate, contractility, and renal perfusion. At higher doses, it also stimulates alpha-adrenergic receptors, causing vasoconstriction and increased blood pressure. ________________________________________ ⚙️ Dosage and Administration Dopacan Injection is administered intravenously, with the dosage tailored to the patient's condition and response: • Low Dose (1–5 mcg/kg/min): Primarily stimulates dopaminergic receptors, increasing renal blood flow and urine output. • Medium Dose (5–15 mcg/kg/min): Stimulates beta-1 adrenergic receptors, enhancing heart rate and contractility. • High Dose (15–50 mcg/kg/min): Stimulates alpha-1 adrenergic receptors, leading to vasoconstriction and increased blood pressure. Continuous monitoring of blood pressure, heart rate, and urine output is essential during administration. ________________________________________ ⚠️ Precautions and Contraindications Before using Dopacan Injection, inform your healthcare provider if you have: • Allergies to dopamine or other components of the injection. • A history of heart rhythm disorders or coronary artery disease. • Pheochromocytoma (a rare tumor of the adrenal glands). • Diabetes, asthma, or sulfite allergies. • Circulatory disorders such as Raynaud's disease or Buerger's disease. • Recent use of monoamine oxidase inhibitors (MAOIs). This medication is typically administered by healthcare professionals in a clinical setting and is not intended for self-administration. ________________________________________ 💊 Side Effects Common side effects may include: • Palpitations or increased heart rate. • Nausea and vomiting. • Headache. • Difficulty breathing. • Gangrene (in rare cases, due to excessive vasoconstriction). Serious side effects are rare but can occur. Seek immediate medical attention if you experience symptoms like chest pain, shortness of breath, or signs of gastrointestinal bleeding.

Cezocalm Injection is a brand name for Chlorpromazine Hydrochloride Injection, manufactured by American Remedies. Chlorpromazine is a first-generation antipsychotic medication belonging to the phenothiazine class. ________________________________________ 🩺 Uses of Cezocalm Injection Cezocalm Injection is primarily used to manage various psychiatric and neurological conditions, including: • Schizophrenia: A chronic mental health disorder characterized by distorted thinking, perception, emotions, and behavior. • Acute Psychotic Episodes: Short-term episodes of severe mental disturbances. • Manic Episodes in Bipolar Disorder: Periods of abnormally elevated mood and energy levels. • Severe Behavioral Problems in Children: Such as hyperactivity and aggression. • Severe Nausea and Vomiting: Especially when other treatments are ineffective. Hiccups: Persistent and intractable cases. • Preoperative Sedation: To relax patients before surgery. ________________________________________ 💊 Mechanism of Action Chlorpromazine works by: Blocking dopamine receptors in the brain, which helps in reducing symptoms of psychosis. • Exhibiting sedative properties by affecting various neurotransmitter systems. ________________________________________ ⚠️ Precautions and Side Effects Before administering Cezocalm Injection, inform your healthcare provider if you have: • Allergies to chlorpromazine or other medications. • A history of liver or kidney disease. • Heart conditions, especially arrhythmias. • Blood disorders. • Seizure disorders. • Pregnancy or breastfeeding status. Common side effects may include: Drowsiness or sedation. • Dizziness. • Dry mouth. • Constipation. • Hypotension (low blood pressure). • Extrapyramidal symptoms (e.g., tremors, rigidity). • Photosensitivity.

Magnesium Chloride Injection is a sterile solution used to treat or prevent magnesium deficiency and related conditions. It's typically given when oral magnesium supplements are ineffective or inappropriate (e.g., in emergencies or hospitalized patients). 🔹 Main Uses of Magnesium Chloride Injection: 🧪 Treatment of Hypomagnesemia (Low Magnesium Levels) Used when blood magnesium levels drop too low, which can cause muscle cramps, fatigue, tremors, and arrhythmias. Common in alcoholics, diabetics, or those with malabsorption syndromes. 🫀 Cardiac Arrhythmias Especially effective in treating: Torsades de pointes (a type of ventricular tachycardia) Irregular heartbeats due to magnesium deficiency. 🤰 Eclampsia and Pre-eclampsia (Pregnancy-related Seizures) Magnesium sulfate is more commonly used, but magnesium chloride may be considered as an alternative. 💨 Severe Asthma Attacks (Adjunct Therapy) Can help relax bronchial smooth muscle and improve breathing during status asthmaticus when other treatments fail. ⚕️ Electrolyte Imbalance Correction Often used with other electrolytes (like potassium) in critical care settings to restore balance in ICU patients. 💉 How It's Given: Intravenously (IV) or Intramuscularly (IM) by a healthcare professional. Dosage depends on the severity of magnesium deficiency or the condition being treated. ⚠️ Precautions & Side Effects: Monitor serum magnesium levels to avoid overdose. High levels can cause: Low blood pressure Flushing Muscle weakness Slow heart rate Respiratory depression or cardiac arrest in severe overdose Use with caution in patients with kidney disease, as magnesium is excreted by the kidneys. ✅ Summary: Condition Use of MgCl Injection Hypomagnesemia ✅ Yes Torsades de Pointes ✅ Yes Pre-eclampsia / Eclampsia ✅ Alternative (to MgSO₄) Severe Asthma (adjunct) ✅ Yes Routine supplementation ⚠️ Only in hospital/clinical setting