About I-Dox 20Mg/10Ml Inj I-Dox 20Mg/10Ml Inj is an anti-cancer medicine used in the treatment of cancer. Cancer is a disease where the cells grow abnormally and divide uncontrollably. I-Dox 20Mg/10Ml Inj is primarily used as adjuvant chemotherapy in women with axillary lymph nodes with involvement resection of breast cancer (abnormal growth in the cells of the breast). It is also used to treat neuroblastoma (cancer that starts in nerve cells and primarily affects children) and Wilms' tumor (a form of kidney cancer that affects children). I-Dox 20Mg/10Ml Inj contains Doxorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, destroying DNA and RNA synthesis. I-Dox 20Mg/10Ml Inj may cause certain side effects such as nausea, headache, abdominal pain, loss of appetite, vomiting, dizziness, mouth sores, tiredness, back pain, red discoloration of urine, diarrhea, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare doctor will administer I-Dox 20Mg/10Ml Inj. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition. I-Dox 20Mg/10Ml Inj should be avoided if you are allergic to it or any other components of this medicine. It is contraindicated in patients having severe myocardial insufficiency, a recent history of myocardial infarction (MI), severe persistent drug-induced myelosuppression, and severe liver disease. Hence, if you have any such conditions, inform your doctor. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, or taking any CYP3A4 or CYP2D6 inducers medication, as it can cause adverse effects. I-Dox 20Mg/10Ml Inj is known to cause embryo-fetal toxicity. Hence, if you are pregnant or breastfeeding, inform your doctor beforehand. Uses of I-Dox 20Mg/10Ml Inj Treatment of Breast Cancer Directions for Use A trained healthcare professional will administer I-Dox 20Mg/10Ml Inj. Hence, do not self-administer. Medicinal Benefits I-Dox 20Mg/10Ml Inj contains Doxorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. I-Dox 20Mg/10Ml Inj is also used in the treatment of acute lymphoblastic leukaemia, acute myeloblastic leukaemia, Hodgkin lymphoma, Non-Hodgkin lymphoma, metastatic breast cancer, metastatic Wilms’ tumour, metastatic neuroblastoma, metastatic soft tissue sarcoma, metastatic bone sarcomas, metastatic ovarian carcinoma, metastatic transitional cell bladder carcinoma, metastatic thyroid carcinoma, metastatic gastric carcinoma, metastatic bronchogenic carcinoma. How I-Dox 20Mg/10Ml Inj Works I-Dox 20Mg/10Ml Inj contains Doxorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, destroying DNA and RNA synthesis. Storage Store in a cool and dry place away from sunlight Side Effects of I-Dox 20Mg/10Ml Inj Nausea Abdominal pain Vomiting Dizziness Back pain Pain at the site of injection Red discolouration of urine Loss of appetite Mouth sores Tiredness Weight gain What if I have taken an overdose of I-Dox 20Mg/10Ml Inj Since I-Dox 20Mg/10Ml Inj is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly. Overdose of I-Dox 20Mg/10Ml Inj may cause sores in the mouth and throat, fever, sore throat, chills, or other signs of infection, unusual bleeding or bruising, black and tarry stools, red blood in stools, and bloody vomit or vomited material that looks like coffee grounds. Drug Warnings I-Dox 20Mg/10Ml Inj should be avoided if you are allergic to it. It is contraindicated in patients having severe myocardial insufficiency, a recent history of myocardial infarction (MI), severe persistent drug-induced myelosuppression and severe liver disease. Hence avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, or taking any CYP3A4 or CYP2D6 inducers medication, as it can cause serious adverse effects. I-Dox 20Mg/10Ml Inj is known to cause embryo-fetal toxicity. Hence it is contraindicated in pregnant or breastfeeding women. Do not stop receiving I-Dox 20Mg/10Ml Inj without a doctor’s advice, as it can cause serious health conditions. I-Dox 20Mg/10Ml Inj is known to cause secondary malignancies.

INTRODUCTION ABOUT I DOX 20MG INJECTION I DOX 20MG INJECTION contains Doxorubicin which belongs to the group of medicines called Anti-cancer agents. It is used to manage certain types of cancers. It is used either alone or along with other anti-cancer medicines. Cancer is a disease in which some of the cells of the body grow uncontrollably and spread to other parts of the body. Before receiving I DOX 20MG INJECTION, inform your doctor if you have or ever had heart disease, either before or during radiotherapy, had or having live or live-attenuated vaccinations, are currently taking or have recently taken Trastuzumab (used in the management of certain cancers). There are no adequate and well-controlled studies in pregnant women. Consult your doctor during breast-feeding before starting management with this medicine as it may pass through the breast milk and possibly harm your child. Consult your doctor for advice before receiving the medicine. The most common side effects of I DOX 20MG INJECTION are infection, lack of appetite, inflammation in the mouth, diarrhea, nausea, vomiting, reddening, swelling, pain, numbness and tingling in the palms and feet may also occur whilst being managed with this medicine. Hair loss is very common and may be quite severe, beard growth may stop in men, fever, feeling weak, chills, abnormal ECG (electrical trace of the heart) results, raised levels of liver enzymes (as detected by a blood test) can determine if the medicine is having an abnormal effect on your liver, weight increased in patients with early breast cancer. USES OF I DOX 20MG INJECTION Used to manage certain types of cancer HOW I DOX 20MG INJECTION WORKS I DOX 20MG INJECTION works by suppressing the activity of an enzyme (topoisomerase II) involved in the DNA multiplication of the cancer cells. On the other hand, this also forms harmful chemicals (free radicals) which cause damage to the DNA. This slowdown the growth of cancer cells and eventually works against them. DIRECTIONS FOR USE I DOX 20MG INJECTION will be administered intravenously (IV) into the vein by your doctor or nurse. Your doctor will administer the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF I DOX 20MG INJECTION COMMON infection lack of appetite inflammation in the mouth diarrhea nausea, vomiting hair loss beard growth may stop (in men) redness, swelling and blistering on the palms of the hands and soles of the feet (palmar-plantar erythrodysesthesia syndrome) chills weakness abnormal ECG raised levels of liver enzymes weight increased in patients with early breast cancer blood poisoning heart problems conjunctivitis (red watery eyes) lacrimation, excess tear production shortness of breath and swelling of the ankles increased heart rate inflammation of the throat and gullet stomach pain skin rashes, redness, hives nails and skin may appear darker than usual injection site reactions such as redness and swelling neutropenia thrombocytopenia malaise/asthenia infertility (in women) absence or decrease in sperm count (in men) UNCOMMON embolism (blockage in the bloodstream) RARE Stop receiving I DOX 20MG INJECTION and contact your doctor immediately if you experience any of the following side effects: dizzy, feverish, short of breath with a tight chest or throat or having an itchy rash anemia (low red blood cell count) decrease in white blood cell counts which in turn causes an increase in infections and a raised temperature (fever) platelets can be affected which could make a bruise or bleed more easily decreased activity in bone marrow reddening of urine dehydration inflammation of veins irritation or bleeding in the intestines inflammation of the lining of the stomach heartburn soreness or ulcers in the mouth

Marketer Getwell Pharma (I) Pvt Ltd SALT COMPOSITION Epirubicin (50mg) Storage Store in a refrigerator (2 - 8°C). Do not freeze. Uses of Epiruba Injection Cancer Breast cancer Non-small cell lung cancer Prostate cancer Cancer of head and neck Stomach cancer Pancreatic cancer Testicular cancer Small cell lung cancer Wilms' tumor Bone cancer Gestational trophoblastic neoplasia Blood cancer Skin cancer Cancer of mouth, nasopharynx and paranasal sinuses, larynx, oesophagus Cervical cancer Ovarian cancer Ewing's sarcoma Product introduction Epiruba 50mg Injection is used in the treatment of various types of cancers of blood, breast, stomach, lung, ovaries and soft tissues. It also helps to prevent the recurrence of bladder cancer after surgery. It is given as a drip or infusion vein with extreme caution by a qualified medical professional. It can be used alone, or sometimes given together with certain other medicines as part of combination chemotherapy. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes contraceptive pills less effective, so it advised to both male and female to use reliable contraception during the treatment. The most common side effects of this medicine include nausea, low blood platelets, hair loss, absence of menstrual periods, fever and rash. It is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Infections can sometimes be life threatening. Regular blood tests are required to monitor your blood cells along with kidney, liver and heart function during treatment with this medicine. Before taking this medicine, tell your doctor if you have liver disease, or have heart problem. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant or breastfeeding. Benefits of Epiruba Injection In Cancer Epiruba 50mg Injection helps to treat certain kinds of cancer. It may be used alone or in combination with other medicines to treat cancer in various parts of the body. Epiruba 50mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated. Side effects of Epiruba Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Epiruba Low blood platelets Nausea Hair loss Absence of menstrual periods Fever Anemia (low number of red blood cells) Diarrhea Weight loss Decreased white blood cell count (neutrophils) Hot flashes Gastrointestinal inflammation Rash Low energy Eye disorder How to use Epiruba Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Epiruba Injection works Epiruba 50mg Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase II) involved in DNA multiplication of the breast cancer cells. It also forms harmful chemicals (free radicals) which cause DNA damage. This slows the growth of breast cancer cells and eventually kills them.

Dutrek is the next generation of joint support and mobility. Dutrek helps to strengthen cartilage, improve joint mobility, and reduce joint stiffness to promote flexibility. It contains clinically proven ingredients such as UC-II*, curcumin, rosehip extract and vitamin D3. UC-II is a patented blend of undenatured type II collage that helps to repair and regenerate cartilage. Unlike hydrolzed collagen which is there is many commercially available brands, undenatured type II collagen has not been exposed to heat and enzymes and thereby helps to trigger body’s own response to repair joints and reduce inflammation. The use of UC-II has been well studied in small animals with osteoarthritis.

Marketer Getwell Pharma (I) Pvt Ltd SALT COMPOSITION Irinotecan (100mg) Storage Store below 25°C Uses of Rinowel Injection Ovarian cancer Small cell lung cancer Cervical cancer Cancer of colon and rectum Uses of Rinowel Injection Ovarian cancer Small cell lung cancer Cervical cancer Cancer of colon and rectum Side effects of Rinowel Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Rinowel Fatigue Nausea Vomiting Weakness Hair loss Fever Anemia (low number of red blood cells) Diarrhea Decreased white blood cell count (neutrophils) Decreased appetite Mucosal inflammation How to use Rinowel Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Rinowel Injection works Rinowel 100mg Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase I) involved in DNA multiplication of the cancer cells. This slows the growth of cancer cells and eventually kills them. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Rinowel 100mg Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Rinowel 100mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding UNSAFE Rinowel 100mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. warnings Driving UNSAFE Rinowel 100mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. warnings Kidney SAFE IF PRESCRIBED Rinowel 100mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Rinowel 100mg Injection may not be needed in these patients. Please consult your doctor. Use of this medicine is not recommended for patients on dialysis. warnings Liver CONSULT YOUR DOCTOR There is limited information available on the use of Rinowel 100mg Injection in patients with liver disease. Please consult your doctor.

Introduction to Lastet 100mg Injection Lastet 100mg injection is an anticancer drug with the ingredient Etoposide. It belongs to the medication class known as cytostatic. It is used to treat certain types of cancers such as testicular cancer, small-cell lung cancer, acute myeloid leukemia (blood cancer), tumor in the lymphatic system (Hodgkin’s lymphoma, non-Hodgkin’s lymphoma), and ovarian cancer in adults. Talk to your doctor if you had or currently having radiotherapy or chemotherapy. Report to your doctor if you have any infections or low levels of protein (albumin) in your blood. Lastet 100mg Injection should not be taken if you have recently been vaccinated with yellow fever or any live vaccines. Before starting treatment with this medicine, it is very important to tell your physician if you currently or previously had any medical conditions of kidney problems or liver disorders. Both women and men should use effective birth control during the treatment and at least 6 months after the last dose. In men, it is recommended not to father a child during and up to 6 months after the treatment. So it is advised to get suggestions about fertility concerns from your doctor. Administration of Lastet 100mg injection may cause a reduction in the level of blood cells and increase the risk of developing infections. So, your doctor may perform blood tests regularly to monitor your kidney and liver function. It is unknown whether it is safe to use on a child. Uses of Lastet 100mg Injection Testicular cancer Small-cell lung cancer Acute myeloid leukemia (blood cancer) Hodgkin’s lymphoma and non-Hodgkin’s lymphoma Ovarian cancer Therapeutic Effects of Lastet 100mg Injection Lastet 100mg works by inhibiting the activity of topoisomerase II (essential for cell replication) and DNA synthesis, which will prevent cancer cells from growing and multiplying, ultimately leading to cell death. Interaction of Lastet 100mg Injection with other drugs Inform your healthcare provider about all your medicines, including prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products. Certain medications such as Ciclosporin, Phenytoin, Phenobarbitone, Warfarin, Anthracyclines, Aspirin, and Fosphenytoin may interact with Lastet 100mg and reduce effectiveness by causing undesirable side effects. More Information about Lastet 100mg Injection Keep Lastet 100mg out of sight and reach of children. Store at a controlled room temperature between 15°C to 30°C. Store in the original package Do not refrigerate or freeze. How to consume Lastet 100mg Injection Lastet 100mg injection is administered as an intravenous infusion into the vein. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administrate. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person. Safety Advices for Lastet 100mg Injection Image Not Available Pregnancy Do not take this Lastet 100mg if you are pregnant because it may cause harm to the unborn baby. Consult your doctor before starting the treatment. Image Not Available Breast Feeding It is unsafe to breastfeed while taking Lastet 100mg because it can cause toxicity to the baby. Please consult your physician for more advice. Image Not Available Lungs Consult your doctor if you experience any lung-related symptoms like; shortness of breath or lung inflammation while taking a Lastet 100mg injection. Image Not Available Liver You need to tell your doctor if you have any liver disorders before taking Lastet 100mg Injection. Your doctor may perform blood tests regularly to monitor your condition. Consult your doctor for more information. Image Not Available Alcohol It is unknown if drinking alcohol while taking a Lastet 100mg injection is safe. Please speak with your physician. Image Not Available Driving Driving while taking a Lastet 100mg injection is unsafe because this medicine can cause tiredness, lightheadedness, or dizziness. Side Effects of Lastet 100mg Injection Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious Severe allergic reactions (swelling of tongue, or throat, breathing difficulties, rash, flushing, fast heartbeat) Irregular heartbeat (arrhythmia) Blood disorder Hepatotoxicity (damage to the liver) Acute leukemia Common Nausea, vomiting Loss of appetite Abdominal pain Constipation, diarrhea Changes in skin color Weakness Asthenia (feeling weak) Temporary hair loss High or low blood pressure Dizziness Redness of the skin Sore lips, throat, or mouth ulcers Word of Advice Discuss your fertility problem with the doctor since, in men, it is advised not to father a child during and after the 6 months of treatment. So it is advised to get suggestions about fertility concerns. Avoid planning for the pregnancy.

Marketer Fresenius Kabi India Pvt Ltd SALT COMPOSITION Irinotecan (100mg) Storage Store below 25°C Uses of Irinotel Injection Ovarian cancer Small cell lung cancer Cervical cancer Cancer of colon and rectum Product introduction Irinotel 100mg Injection is used in the treatment of cancer of colon and rectum. It shows its working by stopping or slowing down the growth of cancer cells. Irinotel 100mg Injection is given as an IV infusion into vein by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include fatigue, nausea, vomiting, weakness, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Inform your doctor if you notice fever, sore throat, and continuous episodes of diarrhea. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels. Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. Side effects of Irinotel Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Irinotel Fatigue Nausea Vomiting Weakness Hair loss Fever Anemia (low number of red blood cells) Diarrhea Decreased white blood cell count (neutrophils) Decreased appetite Mucosal inflammation How to use Irinotel Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Irinotel Injection works Irinotel 100mg Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase I) involved in DNA multiplication of the cancer cells. This slows the growth of cancer cells and eventually kills them. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Irinotel 100mg Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Irinotel 100mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding UNSAFE Irinotel 100mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. warnings Driving UNSAFE Irinotel 100mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Marketer Khandelwal Laboratories Pvt Ltd SALT COMPOSITION Irinotecan (40mg) Storage Store below 30°C Uses of Irinot Injection Ovarian cancer Small cell lung cancer Cervical cancer Cancer of colon and rectum Product introduction Irinot 40mg Injection is used in the treatment of cancer of colon and rectum. It shows its working by stopping or slowing down the growth of cancer cells. Irinot 40mg Injection is given as an IV infusion into vein by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include fatigue, nausea, vomiting, weakness, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Inform your doctor if you notice fever, sore throat, and continuous episodes of diarrhea. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels. Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. Side effects of Irinot Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Irinot Fatigue Nausea Vomiting Weakness Hair loss Fever Anemia (low number of red blood cells) Diarrhea Decreased white blood cell count (neutrophils) Decreased appetite Mucosal inflammation How to use Irinot Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Irinot Injection works Irinot 40mg Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase I) involved in DNA multiplication of the cancer cells. This slows the growth of cancer cells and eventually kills them.

Carodyl contains the most widely used non-steroidal anti-inflammatory drug – Carprofen. Carprofen works by inhibiting an enzyme called cyclooxygenase (COX). This results in lower production of a substance called prostaglandins. By reducing prostaglandin levels, carprofen helps to control pain. Carprofen is a preferential COX 2 inhibitor, with higher ratio of COX 2 to COX 1 inhibition. This is associated with good pain control (analgesic property) with minimal risk of side effects associated with COX 1 inhibition (minimal risk of bleeding). Carodyl Is indicated for the relief of pain and inflammation associated with osteoarthritis and for the control of post-operative pain associated with soft tissue and orthopedic surgeries in dogs.