INTRODUCTION ABALAM 600/300 is a combination of Abacavir and Lamivudine which belongs to the group of medicines called Anti-viral agents. It is used in the management of HIV infection in adults, adolescents and in children (weighing above 25 kgs). HIV (human immunodeficiency virus) infection is a viral infection that damages our immune system and weakens our body’s ability to fight against various infections. Both abacavir and lamivudine are nucleoside reverse transcriptase inhibitors. They work by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. This prevents further multiplication of viral cells within the body. Also, they can improve immunity in the affected patients by increasing the number of certain types of white blood cells (CD4) in the body which is required to fight against various infections. ABALAM 600/300 cannot not manage HIV infection completely. It can reduce only the number of viral cells present in the body and maintains them at a lower level. During management with ABALAM 600/300 your doctor will closely monitor your body weight, blood cholesterol levels and blood sugar levels to reduce the risk of unwanted side effects. Do not take ABALAM 600/300 if you are allergic to abacavir or lamivudine. Before taking ABALAM 600/300 inform your doctor if you have diabetes or any liver (hepatitis C or B infection), kidney or heart problems. If you are already taking ABALAM 600/300 to manage hepatitis B or C infection, do not stop taking it without consulting your doctor. Even if you take ABALAM 600/300, it is important for you to follow certain measures to prevent the spread of infections to the other people (such as avoid having unprotected sexual intercourse or sharing needles or personal items like toothbrush, razors etc with other people). ABALAM 600/300 is not recommended for use in pregnant or breastfeeding women. The most common side effects of taking ABALAM 600/300 are difficulty in sleeping, increased signs of infections, nausea, stomach pain, headache, or dizziness. Consult your doctor if any of these side effects worsens. Also inform your doctor immediately if you experience severe fever with extreme tiredness, sudden changes in body weight or severe stomach pain along with dark urine after taking ABALAM 600/300. USES OF ABALAM 600/300 Manages HIV infection in adults, adolescents and in children (weighing above 25 kgs) HOW ABALAM 600/300 WORKS ABALAM 600/300 is an anti-retroviral medicine. It controls the multiplication of viral cell within the body, by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. It can also improve immunity in the affected patients by increasing the number of certain types of white blood cells (CD4) in the body which is required to fight against various infections. DIRECTIONS FOR USE Take ABALAM 600/300 as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. ABALAM 600/300 can be taken with or without meals. Your doctor will decide the correct dose and for how long ABALAM 600/300 must be taken depending upon your age, body weight and severity of the infection. Do not stop taking ABALAM 600/300 without consulting your doctor as it may reduce its effectiveness. SIDE EFFECTS OF ABALAM 600/300 COMMON difficulty in sleeping feeling depressed headache, tiredness, dizziness nausea, diarrhoea fever, skin rash stomach pain loss of appetite irritated or runny nose hair loss UNCOMMON decrease in RBC, WBC, and platelets RARE Stop taking ABALAM 600/300 and contact your doctor immediately if you experience any of the following side effects: signs of allergic reactions (such as skin rash, fever, accompanied with sore throat, cough, nausea, vomiting, stomach pain, diarrhea, tiredness, joint pain, muscle pain, swelling of the neck, difficulty in breathing, mouth ulcers, occasional headaches, inflammation of the eye, low blood pressure, sense of tingling or numbness of hands or feet) pure red cell aplasia (failure of bone marrow to produce new red blood cells) signs of infections (such as fever, headache, stomach-ache, breathing difficulty) signs of auto-immune disorders (such as rapid or irregular heartbeat, tremor, hyperactivity, general weakness) signs of osteonecrosis (death of bone cells causing joint stiffness, pain in the hip, knee or shoulder and difficulty in moving) signs of liver problems (such as yellowing of the skin and whites of the eye, dark urine, light-coloured stools, loss of appetite, nausea, pain, tenderness on the right side of stomach) heart attack changes in body fat (such as increase fat in the shoulder and neck (buffalo hump), breast, and in the middle body or fat loss from the legs, arms, or face)

INTRODUCTION ABOUT VALCYTE 450MG TABLET VALCYTE 450MG TABLET contains Valganciclovir which belongs to the group of medicines called Antiviral agents. It is used in adults (with acquired immunodeficiency syndrome) to manage cytomegalovirus (CMV) infection of the retina of the eye which generally cause vision problems and blindness. VALCYTE 450MG TABLET is also used in adults and children to manage cytomegalovirus (CMV) infection who are not infected with CMV or who had received an organ transplant from someone who earlier had CMV infection. VALCYTE 450MG TABLET is not recommended for use in patients allergic (hypersensitive) to Valganciclovir, and/or Ganciclovir. Before taking VALCYTE 450MG TABLET, inform your doctor if are undergoing radiotherapy/hemodialysis, and/or suffer from low red blood cell, white blood cell or platelets, kidney/liver problems. VALCYTE 450MG TABLET is not recommended for use in pregnant women unless it is clearly necessary since it may cause harm to the unborn baby. It is also not recommended for use in breastfeeding women. VALCYTE 450MG TABLET should be used with caution in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged 65 years and above) after consulting the doctor. The most common side effects of taking VALCYTE 450MG TABLET are oral thrush (fungal infection), headache, shortness of breath, abdominal pain, loss of appetite, nausea, vomiting, and/or diarrhea. Consult your doctor if any of these symptoms worsens. USES OF VALCYTE 450MG TABLET Manage cytomegalovirus (CMV) infection of the retina of the eye in adult patients with acquired immunodeficiency syndrome (AIDS). Prevents cytomegalovirus (CMV) infection who are not infected with CMV or in patients who had received an organ transplant from someone who earlier had CMV infection HOW VALCYTE 450MG TABLET WORKS VALCYTE 450MG TABLET works by managing the multiplication of virus in human cells by decreasing its growth which results in inhibition of production of new virus thus managing and managing the spread of infection to other parts of the body in affected individuals. DIRECTIONS FOR USE Take VALCYTE 450MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF VALCYTE 450MG TABLET COMMON thrush & oral thrush (fungal infection) upper respiratory tract infection such as sinusitis, tonsillitis headache cough, shortness of breath abdominal pain, loss of appetite, nausea/vomiting, diarrhea, weight loss eczema (skin inflammation) tiredness, fever influenza signs of urine infection such as fever, passing urine more often, and/or pain (while passing urine) skin infection signs of mild allergic reaction such as red, itchy skin feeling depressed, anxious or confused trouble sleeping feeling numb/weak in hands/feet changes in sense of touch, tingling/tickling/pricking/burning sensation altered taste, chills eye inflammation/pain or sight problems ear pain signs of low blood pressure such as feeling dizzy/faint difficulty while swallowing constipation, wind, indigestion, stomach pain, swelling of abdomen mouth ulcers night sweats itching, rash hair loss back pain, muscle/joint pain, muscle spasms feeling dizzy, weak/generally unwell UNCOMMON feeling agitated tremor/shaking deafness irregular heartbeat red itchy welt, dry skin blood in urine chest pain RARE Stop taking VALCYTE 450MG TABLET and contact your doctor if you experience any of the following side effects: signs of allergic reaction (anaphylactic shock) such as raised, itchy skin rash, sudden swelling of throat, face, lips/mouth resulting in difficulty while swallowing/breathing, and/or sudden swelling of the hands, feet/ankles. signs of infection (due to low white blood cell count) such as sore throat, mouth ulcer, and/or fever signs of low red blood cell count such as shortness of breath, tiredness, palpitation, and/or pale skin signs of blood infection (sepsis) such as fever, chills, palpitation, confusion, and/or slurred speech signs of low platelet count such as bleeding/bruising, blood in urine/stools, and/or bleeding from gums severely low blood cell count pancreatitis (inflammation of pancreas) associated with severe stomach pain fits hallucinations abnormal thoughts/feelings, losing contact with reality failure of kidney function HOW TO MANAGE SIDE EFFECTS Constipation Try to eat high-fiber foods such as vegetables, cereals, fresh fruit, and drink plenty of water. Involve in regular exercise (such as going for a daily walk or run) and if this does not help, consult and inform your doctor for receiving alternate managements for constipation.

Introduction to Cytraze 1000mg Injection Cytraze 1000mg injection contains the active substance Cytarabine. It is an antineoplastic drug that belongs to the class antimetabolite. It is used alone or with other chemotherapy medications to treat certain types of leukemias (a type of blood cancer with too many white blood cells), including acute myeloid leukemia (AML) and chronic myelogenous leukemia (CML). It is also indicated to use alone or with other chemotherapy drugs to treat and prevent meningeal leukemia (cancer in the membrane that covers and protects the spinal cord and brain). Do not take Cytraze 1000mg injection if you are allergic to Cytarabine or any other ingredients of this medicine. Inform your physician if you have difficulties in body coordination, or taking any other anti-cancer medications, decreased bone marrow functioning, have liver problems, or have undergone dialysis immediately before or after treatment with this medicine. Cytraze 1000mg injection may cause an increased uric acid level in your blood, your doctor will tell you if you need to take any medicine to control this. Notify your physician if you have sudden signs of allergy, such as rash, itching, or hives on the skin, swelling of the face, lips, mouth, or throat, shortness of breath, or wheezing. It is unknown whether this medicine can be administered in patients with kidney failure, inform your doctor if you have any kidney diseases. Uses of Cytraze 1000mg Injection Acute myeloid leukemia (AML) Chronic myelogenous leukemia (CML) Meningeal leukemia Therapeutic Effects of Cytraze 1000mg Injection Cytraze 1000mg injection is a cytotoxic drug that acts by primarily killing cells undergoing DNA synthesis. It works by slowing or stopping the growth of cancer cells in your body. Interaction of Cytraze 1000mg Injection with other drugs Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, vaccines, and herbal products. Certain medications may interact with the effects of Cytraze 1000mg injection and reduce its effectiveness by causing undesirable side effects. Inform your physician if you are using digoxin. More Information about Cytraze 1000mg Injection Store Cytraze 1000mg injection at room temperature (25°C) Do not refrigerate or freeze. Keep the injection away from the reach of children and pets. If you forgot to take a dose on the scheduled day, contact your physician and reschedule the dose. Do not take a double dose to make up for a forgotten dose. How to consume Cytraze 1000mg Injection Cytraze 1000mg injection will be given to you in a hospital setting by a trained healthcare professional. This medicine may be given by solution for injection/infusion (using a syringe) under the skin (subcutaneous) or into a vein (intravenously) or into a muscle (intramuscularly), or into the spine (intrathecal). Your doctor will decide the dose, route of administration, and duration of the treatment based on your disease condition, severity, and other factors. Safety Advices for Cytraze 1000mg Injection Image Not Available Pregnancy Cytraze 1000mg injection is unsafe to administer in pregnant women because it may cause birth defects. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 6 months after your last dose is necessary. Image Not Available Breast Feeding Breastfeeding is not recommended in patients taking Cytraze 1000mg injection because the medicine passes into the breast milk in small amounts and may harm your baby. Image Not Available Lungs It is unknown whether Cytraze 1000mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment. Image Not Available Liver It is unknown whether Cytraze 1000mg injection can be used in patients with liver disorders. Consult your doctor if you have any liver diseases before starting the treatment. Image Not Available Alcohol It is not known whether it is safe to consume alcohol with Cytraze 1000mg injection. Please consult your doctor. Image Not Available Driving Cytraze 1000mg injection does not affect your ability to drive or use machinery. If you are affected, consult your doctor for more advice. Side Effects of Cytraze 1000mg Injection Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Fever Loss of appetite, abdominal pain Swallowing difficulties Nausea, vomiting Diarrhoea Inflammation or ulceration in the mouth or anus High blood uric acid levels Hair loss Skin rashes Speaking difficulties Inflammation in the vein Serious Swelling and irritation of the skin Increased blood uric acid levels Blisters of the skin Irregular heartbeat Lung diseases Anemia

What is Encorate Chrono 300 Tablet CR Encorate Chrono 300 Tablet CR is an antiepileptic medication containing Sodium Valproate and Valproic Acid. It is primarily used to control seizures, prevent migraines, and manage bipolar disorder. Abbott manufactures Encorate Chrono 300 Tablet CR, which stabilizes electrical activity in the brain and increases GABA levels, a neurotransmitter that helps calm the nervous system. Uses of Encorate Chrono 300 Tablet CR Encorate Chrono 300 Tablet CR offers several benefits in treating various neurological conditions: Seizure control: Effectively manages different types of seizures, including generalized and absent seizures. Migraine prevention: Helps in reducing the frequency and severity of migraines. Bipolar disorder treatment: Assists in stabilizing mood swings associated with bipolar disorder. Improved GABA levels: Enhances the activity of GABA, reducing abnormal brain activity. How to use Encorate Chrono 300 Tablet CR Follow these general steps to use Encorate Chrono 300 Tablet CR correctly: Take the tablet with or without food as prescribed by your doctor. Swallow the tablet whole; do not chew, crush, or break it. Take it at the same time every day to maintain consistent drug levels. Do not stop taking the medication suddenly without consulting your doctor. Strengths and Substitutes Encorate Chrono 300 Tablet CR is available in various strengths and substitutes. Your doctor may adjust your dosage based on your specific condition and response to treatment. What are the side effects of Encorate Chrono 300 Tablet CR Like all medications, Encorate Chrono 300 Tablet CR can cause side effects, though not everyone experiences them. Common side effects include: Drowsiness Nausea Weight gain Tremors Hair loss If you experience severe side effects, contact your doctor immediately. Safety Advice Liver problemsLiver disease Regular monitoring of liver function is essential. Inform your doctor if you notice signs of liver damage, such as jaundice or severe abdominal pain. CardiovascularKidney impairment Use with caution in patients with kidney impairment. Dose adjustments may be necessary. PregnancyPregnant and breastfeeding women Not recommended during pregnancy or breastfeeding due to potential risks to the baby. wineAvoid Avoid alcohol, driving, and operating heavy machinery, as the medication may cause drowsiness or dizziness.

PYOclean® Spray is an innovative and patented purifying care to help manage localized cutaneous microbiota imbalances (superficial pyoderma and Malassezia dermatitis): pimples, scabs, etc. From the first signs of relapses. Thanks to its ingredients of 100% natural origin, PYOclean® Spray is a unique emulsion that also helps promote the skin’s natural defenses thanks to a prebiotic. PYOclean® Spray moisturizes, and helps reinforce the skin barrier. Thanks to its original patented texture, PYOclean® Spray perfectly adheres to the area, without massage, for a lasting action.

Timipar (Timolol Maleate 0.5%) Ophthalmic Solution is a prescription eye drop used to manage elevated intraocular pressure (IOP) in conditions such as open-angle glaucoma and ocular hypertension. By reducing the production of fluid within the eye, it helps lower IOP, thereby reducing the risk of optic nerve damage and potential vision loss. ________________________________________ ✅ Primary Uses • Open-Angle Glaucoma: A common form of glaucoma where the drainage angle in the eye remains open, but the trabecular meshwork is partially blocked, leading to increased IOP. • Ocular Hypertension: A condition characterized by higher-than-normal IOP without any signs of glaucoma damage. ________________________________________ 💊 Dosage and Administration • Typical Dosage: Instill one drop of the 0.5% solution into the affected eye(s) twice daily. • Application Tips: o Wash your hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. o After instilling the drop, gently press the corner of your eye (near the nose) for 1–2 minutes to prevent the medication from draining out. ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: o Hypersensitivity to any component of the formulation. o Bronchial asthma or a history of bronchial asthma. o Severe chronic obstructive pulmonary disease (COPD). o Sinus bradycardia, second- or third-degree atrioventricular block, overt cardiac failure, or cardiogenic shock. • Cautions: o Use with caution in patients with a history of heart disease, diabetes, or thyroid disorders, as beta-blockers can mask symptoms of hypoglycemia and hyperthyroidism. o Monitor for potential additive effects when used with other systemic beta-blockers. ________________________________________ 🧪 Mechanism of Action Timolol is a non-selective beta-adrenergic antagonist (beta-blocker) that reduces aqueous humor production in the eye, leading to a decrease in IOP. Its onset of action is typically within 20 minutes, with effects lasting up to 24 hours.

Timipar (Timolol Maleate 0.25%) eye drops are a prescription medication primarily used to manage elevated intraocular pressure (IOP) associated with conditions like open-angle glaucoma and ocular hypertension. By reducing the production of aqueous humor, the fluid inside the eye, Timolol helps lower IOP, thereby reducing the risk of optic nerve damage and potential vision loss . ________________________________________ ✅ Primary Uses • Open-Angle Glaucoma: A common type of glaucoma where the drainage angle in the eye remains open, but the trabecular meshwork is partially blocked, leading to increased IOP. • Ocular Hypertension: A condition characterized by higher-than-normal IOP without any signs of glaucoma damage. ________________________________________ 💊 Dosage and Administration • Typical Dosage: Instill one drop of the 0.25% solution into the affected eye(s) once or twice daily, as directed by your healthcare provider. • Application Tips: o Wash your hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them . ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: o Hypersensitivity to any component of the formulation. o Bronchial asthma or a history of bronchial asthma. o Severe chronic obstructive pulmonary disease (COPD). • Sinus bradycardia, second- or third-degree atrioventricular block, overt cardiac failure, or cardiogenic shock . • Cautions: o Use with caution in patients with a history of heart disease, diabetes, or thyroid disorders, as beta-blockers can mask symptoms of hypoglycemia and hyperthyroidism. o Monitor for potential additive effects when used with other systemic beta-blockers . ________________________________________ 🧪 Mechanism of Action Timolol is a non-selective beta-adrenergic antagonist (beta-blocker) that reduces aqueous humor production in the eye, leading to a decrease in IOP. Its onset of action is typically within 20 minutes, with effects lasting up to 24 hours .

Paristin-Z (Sulphacetamide & Zinc Sulphate) Eye Drops Uses: • Bacterial Eye Infections: Paristin-Z is primarily used to treat bacterial eye infections such as conjunctivitis (pink eye), blepharitis (inflammation of the eyelids), and other superficial eye infections caused by susceptible bacteria. • Eye Irritation Relief: The combination of Sulphacetamide and Zinc Sulphate helps alleviate symptoms like redness, itching, and discharge associated with eye infections. Dosage: • Typical Dosage: Instill 1–2 drops into the affected eye(s) every 3 to 4 hours, or as directed by your healthcare provider. • Application Method: 1. Wash your hands thoroughly before use. 2. Tilt your head back and gently pull down the lower eyelid to create a small pocket. 3. Place the dropper tip near the eye without touching it. 4. Squeeze the prescribed number of drops into the pocket. 5. Close your eye and blink several times to spread the solution evenly. Precautions: • Allergic Reactions: If you experience signs of an allergic reaction such as rash, itching, swelling, or difficulty breathing, discontinue use and consult your doctor immediately. • Contact Lenses: Avoid wearing contact lenses during the course of treatment unless advised otherwise by your healthcare provider. • Pregnancy and Breastfeeding: Consult your doctor before using Paristin-Z if you are pregnant or breastfeeding. Side Effects: • Common Side Effects: o Temporary burning or stinging upon application. o Mild irritation or redness. o Temporary blurred vision. • Serious Side Effects: o Persistent eye pain or swelling. o Worsening of vision. o Signs of an allergic reaction (rash, itching, swelling).

Paristin-C (Sulphacetamide & Chloramphenicol) Eye/Ear Drops Paristin-C is a combination ophthalmic and otic solution containing Sulphacetamide (20% w/v) and Chloramphenicol (0.5% w/v). It is primarily used to treat bacterial infections of the eye and ear. ________________________________________ 🔍 Uses • Bacterial Eye Infections: Effective in treating conditions such as conjunctivitis (pink eye), blepharitis (inflammation of the eyelids), and other superficial eye infections caused by susceptible bacteria. • Bacterial Ear Infections: Used to treat external ear infections (otitis externa) caused by bacteria. ________________________________________ 💧 Dosage and Administration • For Eye Infections: o Instill 1–2 drops into the affected eye(s) every 3 to 4 hours, or as directed by your healthcare provider. o Continue the full course of treatment even if symptoms improve to ensure complete eradication of the infection. o Apply 2–3 drops into the affected ear canal, 3 to 4 times daily, or as prescribed by your doctor. o Keep the head tilted for a few minutes to allow the medication to reach the affected area. ________________________________________ ⚠️ Side Effects and Precautions • Common Side Effects: o Mild irritation or burning sensation upon application. o Temporary blurred vision (for eye drops). o Ear discomfort or itching (for ear drops). • Serious Side Effects: o Signs of an allergic reaction, such as rash, itching, swelling, or difficulty breathing. o Persistent redness or discomfort in the eye or ear. • Precautions: o Do not touch the dropper tip to any surface to avoid contamination. o If using contact lenses, remove them before applying the eye drops and wait at least 15 minutes before reinserting. o Consult your healthcare provider before use if you are pregnant, breastfeeding, or have a history of allergies to sulfonamides or chloramphenicol. ________________________________________