Introduction to Xapavir 50mg Tablet Xapavir 50mg Tablet is an antiviral drug belonging to the Integrase strand transfer inhibitor category, containing the active ingredient Dolutegravir. It is used to treat human immunodeficiency virus (HIV) infection. HIV infection is mainly spread by sexual contact with anyone who has the infection or by transfer of infected blood (by sharing injection needles). This drug must be taken with other medicines used to treat HIV infection. This drug is contraindicated in individuals with liver disease. Due to the higher concentration, caution should be taken when administering the drug to individuals with liver impairment. The dosage of this drug may need to be adjusted by your doctor, or it may need to be used with extra monitoring in these individuals to ensure its safety and efficacy. During the early stages of HIV treatment, some patients may experience an inflammatory response to opportunistic infections. This condition, immune reconstitution syndrome, can occur after starting the drug or other antiretroviral therapies. Knowing this possibility and monitoring for any signs of worsening infections or inflammatory symptoms is necessary. Inform your healthcare provider if the symptoms concern you or persist longer than usual. It is necessary for healthcare professionals to carefully monitor patients taking this drug for any signs or symptoms of skin or hypersensitivity reactions, such as rash, blistering, or mucosal lesions. If a severe reaction is suspected, this medicine should be discontinued immediately, and appropriate medical treatment can be initiated. Patients are also advised to report any skin or hypersensitivity reactions to their healthcare provider and to seek medical emergency immediately if they experience any symptoms of a severe reaction. Tell your doctor immediately about all the medications you have been taking recently, including herbal and supplements, before taking this drug. Uses of Xapavir 50mg Tablet Human Immunodeficiency Virus (HIV) Therapeutic Effects of Xapavir 50mg Tablet Xapavir 50mg Tablet works by inhibiting the enzyme integrase, thereby reducing the virus in your body. It also increases a type of white blood cell called CD4 cells which help the body fight infection. Interaction of Xapavir 50mg Tablet with other drugs Inform your healthcare provider about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Xapavir 50mg Tablets and reduce effectiveness by causing undesirable side effects. More Information about Xapavir 50mg Tablet Store Xapavir 50mg Tablet at room temperature (15°to 25°C). Keep the Tablet out of reach of children and pets. How to consume Xapavir 50mg Tablet It is an orally available prescription drug. Your doctor will decide the dose and duration of the drug based on the disease condition and other factors. Always take Xapavir 50mg Tablet as prescribed by your doctor. Take the Tablet with or without food. Do not break, chew, or crush the Tablet. Swallow the whole Tablet with water. Safety Advices for Xapavir 50mg Tablet Image Not Available Pregnancy Suppose you are pregnant or planning for pregnancy during the treatment. Please consult your doctor before taking Xapavir 50mg Tablet. Image Not Available Breast Feeding Breastfeeding is not recommended in patients taking Xapavir 50mg Tablets because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment. Image Not Available Lungs It is unknown whether Xapavir 50mg Tablets can be prescribed for patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment. Image Not Available Liver Xapavir 50mg Tablet must be cautiously administered in patients with severe liver diseases. Dose adjustments are necessary for severe liver failure. Inform your doctor if you have liver problems before initiating the therapy Image Not Available Alcohol Consuming alcohol may affect the effectiveness of the Xapavir 50mg Tablet. It is highly advised to stop consuming alcohol if you take this medicine. Image Not Available Driving Driving vehicles or operating heavy machinery is unsafe after taking the Xapavir 50mg Tablet. It may cause dizziness and impair concentration. Side Effects of Xapavir 50mg Tablet Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Allergic reactions (swelling, high temperature) Infection, inflammation Inflammation of the liver; liver failure Joint pain Common Depression Abnormal dreams, insomnia Itching, rash Being sick Stomach discomfort, pain Headache Diarrhea Fatigue

INTRODUCTION ABOUT I DOX 20MG INJECTION I DOX 20MG INJECTION contains Doxorubicin which belongs to the group of medicines called Anti-cancer agents. It is used to manage certain types of cancers. It is used either alone or along with other anti-cancer medicines. Cancer is a disease in which some of the cells of the body grow uncontrollably and spread to other parts of the body. Before receiving I DOX 20MG INJECTION, inform your doctor if you have or ever had heart disease, either before or during radiotherapy, had or having live or live-attenuated vaccinations, are currently taking or have recently taken Trastuzumab (used in the management of certain cancers). There are no adequate and well-controlled studies in pregnant women. Consult your doctor during breast-feeding before starting management with this medicine as it may pass through the breast milk and possibly harm your child. Consult your doctor for advice before receiving the medicine. The most common side effects of I DOX 20MG INJECTION are infection, lack of appetite, inflammation in the mouth, diarrhea, nausea, vomiting, reddening, swelling, pain, numbness and tingling in the palms and feet may also occur whilst being managed with this medicine. Hair loss is very common and may be quite severe, beard growth may stop in men, fever, feeling weak, chills, abnormal ECG (electrical trace of the heart) results, raised levels of liver enzymes (as detected by a blood test) can determine if the medicine is having an abnormal effect on your liver, weight increased in patients with early breast cancer. USES OF I DOX 20MG INJECTION Used to manage certain types of cancer HOW I DOX 20MG INJECTION WORKS I DOX 20MG INJECTION works by suppressing the activity of an enzyme (topoisomerase II) involved in the DNA multiplication of the cancer cells. On the other hand, this also forms harmful chemicals (free radicals) which cause damage to the DNA. This slowdown the growth of cancer cells and eventually works against them. DIRECTIONS FOR USE I DOX 20MG INJECTION will be administered intravenously (IV) into the vein by your doctor or nurse. Your doctor will administer the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF I DOX 20MG INJECTION COMMON infection lack of appetite inflammation in the mouth diarrhea nausea, vomiting hair loss beard growth may stop (in men) redness, swelling and blistering on the palms of the hands and soles of the feet (palmar-plantar erythrodysesthesia syndrome) chills weakness abnormal ECG raised levels of liver enzymes weight increased in patients with early breast cancer blood poisoning heart problems conjunctivitis (red watery eyes) lacrimation, excess tear production shortness of breath and swelling of the ankles increased heart rate inflammation of the throat and gullet stomach pain skin rashes, redness, hives nails and skin may appear darker than usual injection site reactions such as redness and swelling neutropenia thrombocytopenia malaise/asthenia infertility (in women) absence or decrease in sperm count (in men) UNCOMMON embolism (blockage in the bloodstream) RARE Stop receiving I DOX 20MG INJECTION and contact your doctor immediately if you experience any of the following side effects: dizzy, feverish, short of breath with a tight chest or throat or having an itchy rash anemia (low red blood cell count) decrease in white blood cell counts which in turn causes an increase in infections and a raised temperature (fever) platelets can be affected which could make a bruise or bleed more easily decreased activity in bone marrow reddening of urine dehydration inflammation of veins irritation or bleeding in the intestines inflammation of the lining of the stomach heartburn soreness or ulcers in the mouth

INTRODUCTION ABOUT RITUXIREL 100 INJECTION RITUXIREL 100 INJECTION contains Rituximab which belongs to the group of medicines called Anticancer drugs. It is used to manage blood cancer (leukaemia) and lymph cancer (lymphoma). It can also be used to manage various auto-immune disease conditions such as rheumatoid arthritis, granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels) and pemphigus vulgaris (severe skin blistering and peeling especially on the mouth, nose, throat, eyes and genitals). It is mostly used in combination with other cytotoxic anticancer agents to achieve better results. It is suitable for use both in adults and in children (aged 6 months or older). RITUXIREL 100 INJECTION will be administered to you only by an oncologist or a trained professional into your vein (as intravenous infusion). Before receiving RITUXIREL 100 INJECTION inform your doctor if you have any heart problems (such as chest pain, heart attack, heart failure or abnormal heartbeat). You must also inform your doctor if you currently have or previously had hepatitis B infection or any other mild infections (including minor cough and cold) as a precaution. RITUXIREL 100 INJECTION is not recommended for use in pregnant or breastfeeding women. Both men and women receiving RITUXIREL 100 INJECTION must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with RITUXIREL 100 INJECTION. The most common side effects of receiving this medicine are fever, chills, skin rashes with itching, shortness of breath and low blood pressure. Consult your doctor if any of these side effect worsens. USES OF RITUXIREL 100 INJECTION It is used to manage: Blood cancer (Chronic lymphocytic leukaemia) Lymph cancer (Non-Hodgkin’s Lymphoma) Rheumatoid arthritis (joint pain and inflammation) Granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels) Pemphigus vulgaris (severe skin blistering and peeling especially on the mouth, nose, throat, eyes and genitals) HOW RITUXIREL 100 INJECTION WORKS RITUXIREL 100 INJECTION is a monoclonal antibody. It destroys the immune cells (B-cells) that triggers cancer formation. It also reduces the production of certain chemicals within the body (such as rheumatoid factor, T-cells, cytokines) that causes inflammation, pain and swelling which helps in managing various autoimmune diseases. DIRECTIONS FOR USE RITUXIREL 100 INJECTION will be given to you only by a doctor or a nurse into the vein (intravenously). Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF RITUXIREL 100 INJECTION COMMON increased infections (bacterial, viral or fungal) low RBC, WBC and platelet counts in blood nausea, vomiting, diarrhea, stomach pain, constipation, indigestion mouth ulcers hair loss fever, chills, pneumonia, shingles, cold, sinusitis thrush, urinary tract infection headache, dizziness, tiredness, weakness hepatitis B infection high blood sugar and cholesterol levels weight loss, lack of appetite numbness, tingling, pricking, burning sensation on the skin restlessness, problems in falling asleep, anxiety, depression flushing (skin redness) eye inflammation or watery eyes ringing sound in the ears, ear pain uneven or fast heart rate, high or low blood pressure shortness of breath, runny nose, nasal itching and repeated sneezing increased sweating, night sweats muscle pain, joint pain, back pain, neck pain pain while passing urine fungal foot infection (athlete’s foot) tremors (shakiness) swelling of the hands or ankles UNCOMMON blood clotting problems changes in taste slow heart rate chest tightness and lung problems RARE Contact your doctor immediately if you experience any of the following side effects: fever, chills, shivering, nausea, vomiting, skin rashes with blisters and itching, flushing, pain at the infusion site, headache, tiredness, wheezing, high blood pressure, palpitations, swelling of throat or tongue, runny or itchy nose and chest pain fever, cough, sore throat, burning pain while passing urine, feeling weak or generally unwell signs of brain problem (such as memory loss, trouble thinking, difficulty in walking or vision problems) signs of severe skin reactions (such as severe skin blistering and redness that may appear on the on the mucous membranes, such as inside the mouth, the genital areas or the eyelids, with fever)

INTRODUCTION ABOUT RITUXIREL 500MG INJECTION RITUXIREL 500MG INJECTION contains Rituximab which belongs to the group of medicines called Anticancer drugs. It is used to manage blood cancer (leukaemia) and lymph cancer (lymphoma). It can also be used to manage various auto-immune disease conditions such as rheumatoid arthritis, granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels) and pemphigus vulgaris (severe skin blistering and peeling especially on the mouth, nose, throat, eyes and genitals). It is mostly used in combination with other cytotoxic anticancer agents to achieve better results. It is suitable for use both in adults and in children (aged 6 months or older). RITUXIREL 500MG INJECTION will be administered to you only by an oncologist or a trained professional into your vein (as intravenous infusion). Before receiving RITUXIREL 500MG INJECTION inform your doctor if you have any heart problems (such as chest pain, heart attack, heart failure or abnormal heartbeat). You must also inform your doctor if you currently have or previously had hepatitis B infection or any other mild infections (including minor cough and cold) as a precaution. RITUXIREL 500MG INJECTION is not recommended for use in pregnant or breastfeeding women. Both men and women receiving RITUXIREL 500MG INJECTION must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with RITUXIREL 500MG INJECTION. The most common side effects of receiving this medicine are fever, chills, skin rashes with itching, shortness of breath and low blood pressure. Consult your doctor if any of these side effect worsens. USES OF RITUXIREL 500MG INJECTION It is used to manage: Blood cancer (Chronic lymphocytic leukaemia) Lymph cancer (Non-Hodgkin’s Lymphoma) Rheumatoid arthritis (joint pain and inflammation) Granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels) Pemphigus vulgaris (severe skin blistering and peeling especially on the mouth, nose, throat, eyes and genitals) HOW RITUXIREL 500MG INJECTION WORKS RITUXIREL 500MG INJECTION is a monoclonal antibody. It destroys the immune cells (B-cells) that triggers cancer formation. It also reduces the production of certain chemicals within the body (such as rheumatoid factor, T-cells, cytokines) that causes inflammation, pain and swelling which helps in managing various autoimmune diseases. DIRECTIONS FOR USE RITUXIREL 500MG INJECTION will be given to you only by a doctor or a nurse into the vein (intravenously). Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF RITUXIREL 500MG INJECTION COMMON increased infections (bacterial, viral or fungal) low RBC, WBC and platelet counts in blood nausea, vomiting, diarrhea, stomach pain, constipation, indigestion mouth ulcers hair loss fever, chills, pneumonia, shingles, cold, sinusitis thrush, urinary tract infection headache, dizziness, tiredness, weakness hepatitis B infection high blood sugar and cholesterol levels weight loss, lack of appetite numbness, tingling, pricking, burning sensation on the skin restlessness, problems in falling asleep, anxiety, depression flushing (skin redness) eye inflammation or watery eyes ringing sound in the ears, ear pain uneven or fast heart rate, high or low blood pressure shortness of breath, runny nose, nasal itching and repeated sneezing increased sweating, night sweats muscle pain, joint pain, back pain, neck pain pain while passing urine fungal foot infection (athlete’s foot) tremors (shakiness) swelling of the hands or ankles UNCOMMON blood clotting problems changes in taste slow heart rate chest tightness and lung problems RARE Contact your doctor immediately if you experience any of the following side effects: fever, chills, shivering, nausea, vomiting, skin rashes with blisters and itching, flushing, pain at the infusion site, headache, tiredness, wheezing, high blood pressure, palpitations, swelling of throat or tongue, runny or itchy nose and chest pain fever, cough, sore throat, burning pain while passing urine, feeling weak or generally unwell signs of brain problem (such as memory loss, trouble thinking, difficulty in walking or vision problems) signs of severe skin reactions (such as severe skin blistering and redness that may appear on the on the mucous membranes, such as inside the mouth, the genital areas or the eyelids, with fever) HOW TO MANAGE SIDE EFFECTS Constipation Try to eat more high-fibre foods such as fresh fruit, vegetables, cereals, and drink plenty of water. Try doing exercise regularly (going for a daily walk or run). If this does not help, inform your doctor for receiving alternate managements for constipation.

Paristin-Z (Sulphacetamide & Zinc Sulphate) Eye Drops Uses: • Bacterial Eye Infections: Paristin-Z is primarily used to treat bacterial eye infections such as conjunctivitis (pink eye), blepharitis (inflammation of the eyelids), and other superficial eye infections caused by susceptible bacteria. • Eye Irritation Relief: The combination of Sulphacetamide and Zinc Sulphate helps alleviate symptoms like redness, itching, and discharge associated with eye infections. Dosage: • Typical Dosage: Instill 1–2 drops into the affected eye(s) every 3 to 4 hours, or as directed by your healthcare provider. • Application Method: 1. Wash your hands thoroughly before use. 2. Tilt your head back and gently pull down the lower eyelid to create a small pocket. 3. Place the dropper tip near the eye without touching it. 4. Squeeze the prescribed number of drops into the pocket. 5. Close your eye and blink several times to spread the solution evenly. Precautions: • Allergic Reactions: If you experience signs of an allergic reaction such as rash, itching, swelling, or difficulty breathing, discontinue use and consult your doctor immediately. • Contact Lenses: Avoid wearing contact lenses during the course of treatment unless advised otherwise by your healthcare provider. • Pregnancy and Breastfeeding: Consult your doctor before using Paristin-Z if you are pregnant or breastfeeding. Side Effects: • Common Side Effects: o Temporary burning or stinging upon application. o Mild irritation or redness. o Temporary blurred vision. • Serious Side Effects: o Persistent eye pain or swelling. o Worsening of vision. o Signs of an allergic reaction (rash, itching, swelling).

Paristin-C (Sulphacetamide & Chloramphenicol) Eye/Ear Drops Paristin-C is a combination ophthalmic and otic solution containing Sulphacetamide (20% w/v) and Chloramphenicol (0.5% w/v). It is primarily used to treat bacterial infections of the eye and ear. ________________________________________ 🔍 Uses • Bacterial Eye Infections: Effective in treating conditions such as conjunctivitis (pink eye), blepharitis (inflammation of the eyelids), and other superficial eye infections caused by susceptible bacteria. • Bacterial Ear Infections: Used to treat external ear infections (otitis externa) caused by bacteria. ________________________________________ 💧 Dosage and Administration • For Eye Infections: o Instill 1–2 drops into the affected eye(s) every 3 to 4 hours, or as directed by your healthcare provider. o Continue the full course of treatment even if symptoms improve to ensure complete eradication of the infection. o Apply 2–3 drops into the affected ear canal, 3 to 4 times daily, or as prescribed by your doctor. o Keep the head tilted for a few minutes to allow the medication to reach the affected area. ________________________________________ ⚠️ Side Effects and Precautions • Common Side Effects: o Mild irritation or burning sensation upon application. o Temporary blurred vision (for eye drops). o Ear discomfort or itching (for ear drops). • Serious Side Effects: o Signs of an allergic reaction, such as rash, itching, swelling, or difficulty breathing. o Persistent redness or discomfort in the eye or ear. • Precautions: o Do not touch the dropper tip to any surface to avoid contamination. o If using contact lenses, remove them before applying the eye drops and wait at least 15 minutes before reinserting. o Consult your healthcare provider before use if you are pregnant, breastfeeding, or have a history of allergies to sulfonamides or chloramphenicol. ________________________________________

HYLA FRESH (Sodium Hyaluronate) Eye Drops are designed to provide relief for dry, tired, or irritated eyes. These drops combine sodium hyaluronate with Euphrasia officinalis (Eyebright) extract, offering a soothing effect for various eye discomforts. ________________________________________ 🔍 Uses • Dry Eye Relief: HYLA FRESH helps alleviate dryness caused by environmental factors such as air conditioning, heating, or prolonged screen time. • Contact Lens Comfort: Provides lubrication to reduce discomfort associated with contact lens wear. Environmental Irritation: Soothes eyes irritated by wind, dust, or pollen exposure. Post-Surgical Care: Assists in the healing process following eye surgeries by maintaining moisture and reducing irritation. ________________________________________ 💧 Dosage and Administration • General Dosage: Instill 1–2 drops into the affected eye(s) as needed. • Application Method: 1. Wash your hands thoroughly. 2. Tilt your head back and gently pull down the lower eyelid to create a small pocket. 3. Place the dropper tip near the eye without touching it. 4. Squeeze the bottle to release the prescribed number of drops. 5. Close your eye and blink several times to spread the solution evenly. ________________________________________ ⚠️ Side Effects and Precautions • Common Side Effects: o Temporary blurred vision. o Mild burning or stinging sensation upon application. • Serious Side Effects: o Persistent eye discomfort or redness. o Signs of an allergic reaction (rash, itching, swelling). • Precautions: o Consult a healthcare provider before use if you have any known allergies to the ingredients. o Avoid touching the dropper tip to any surface to prevent contamination. o If you wear contact lenses, remove them before applying the drops unless otherwise directed by your doctor.

SGOS-5 (Sodium Chloride 5% Ophthalmic Solution) is a hypertonic saline eye drop primarily used to treat corneal edema—a condition where the cornea swells due to fluid accumulation, leading to blurred vision and discomfort. ________________________________________ 🔍 Uses • Corneal Edema Management: SGOS-5 helps reduce swelling in the cornea by drawing out excess fluid, thereby improving vision clarity. Post-Surgical Care: It is commonly used after eye surgeries like cataract operations to alleviate corneal swelling. • Treatment of Corneal Disorders: Conditions such as Fuchs' dystrophy or bullous keratopathy, which cause fluid buildup in the cornea, can be managed with SGOS-5. ________________________________________ 💧 Dosage and Administration • Typical Dosage: Instill 1–2 drops into the affected eye(s) every 3 to 4 hours, or as directed by your healthcare provider. • Application Tips: 1. Wash your hands thoroughly before use. 2. Tilt your head back and gently pull down the lower eyelid to form a pocket. 3. Squeeze the prescribed number of drops into the pocket. 4. Close your eye and apply gentle pressure to the inner corner for 1–2 minutes to prevent drainage. 5. Avoid touching the dropper tip to any surface to maintain sterility. ________________________________________ ⚠️ Side Effects and Precautions • Common Side Effects: o Temporary burning or stinging upon application. o Mild irritation or redness. • Temporary blurred vision. • Serious Side Effects: o Persistent eye pain or swelling. o Worsening of vision. • Signs of an allergic reaction (rash, itching, swelling). • Precautions: o Use under medical supervision, especially if you have thyroid disorders. o Not recommended for use in infants under one month of age. o Avoid concurrent use with other antiseptic eye drops containing mercury-based preservatives or sodium thiosulfate.

Povar (Povidone Iodine) Eye Drops are antiseptic ophthalmic solutions primarily used for preoperative and postoperative eye care, as well as for certain eye infections. The active ingredient, povidone-iodine, is a broad-spectrum antimicrobial agent effective against bacteria, viruses, and fungi. ________________________________________ 🔍 Uses of Povidone Iodine Eye Drops 1. Preoperative Antisepsis Applied to the ocular surface before eye surgeries such as cataract or glaucoma procedures to reduce the risk of postoperative infections. 2. Postoperative Care Used after eye surgeries to prevent infection and promote healing of the ocular surface. 3. Treatment of Conjunctivitis In some cases, povidone-iodine eye drops are used to treat bacterial or viral conjunctivitis, commonly known as pink eye. 4. Prevention of Ophthalmia Neonatorum Instilled in newborns' eyes shortly after birth to prevent gonococcal or chlamydial eye infections. ________________________________________ ⚠️ Safety and Side Effects • Common Side Effects Temporary stinging or burning sensation upon application. Mild irritation or redness of the eye. Temporary yellow discoloration of the whites of the eyes or surrounding skin. Serious Side Effects Signs of an allergic reaction, such as rash, itching, swelling, or difficulty breathing. If any of these occur, seek immediate medical attention. Precautions o Do not use if allergic to iodine or any components of the product. o Use with caution in individuals with thyroid disorders due to potential iodine absorption. o Not recommended for use in infants under one month of age. o Avoid concurrent use with other antiseptic eye drops containing mercury-based preservatives or sodium thiosulfate.