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'rare systemic absorption'

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Eye Care

Paricar (Pilocarpine Nitrate 4%) Eye Drops are a miotic ophthalmic solution primarily used to manage certain eye conditions by reducing intraocular pressure. ________________________________________ 🔍 Uses 1. Treatment of Glaucoma and Ocular Hypertension Pilocarpine Nitrate 4% is employed to lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. It facilitates the drainage of aqueous humor from the eye, thereby reducing IOP and helping prevent vision loss and nerve damage. 2. Management of Acute Angle-Closure Glaucoma In acute angle-closure glaucoma, Pilocarpine Nitrate 4% may be used to constrict the pupil, facilitating the opening of the angle between the iris and cornea, which helps in reducing IOP. 3. Induction of Miosis Pilocarpine Nitrate 4% is utilized to induce miosis (pupil constriction) during certain eye surgeries or to reverse the effects of drugs used to dilate the pupil during eye examinations. ________________________________________ 💧 Dosage and Administration • General Dosage: Instill one drop into the affected eye(s) 1 to 4 times daily, as directed by your healthcare provider. • Application Method: 1. Wash your hands thoroughly before use. 2. Tilt your head back slightly and pull down the lower eyelid to form a pouch. 3. Hold the dropper above the eye and instill the prescribed number of drops. 4. Close the eye gently and apply gentle pressure to the inner corner of the eye for 1 to 2 minutes to prevent the medication from draining away. 5. Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. ________________________________________ ⚠️ Safety and Side Effects • Common Side Effects: o Temporary eye discomfort, such as stinging or burning sensations. o Blurred vision. o Headache. • Visual disturbances. • Serious Side Effects: o Although rare, systemic absorption may lead to increased blood pressure, headache, or dizziness. • Precautions: o Consult your doctor if you are pregnant or breastfeeding, as the safety of Pilocarpine Nitrate 4% during these periods is not well-established. o Use with caution if you have a history of retinal diseases or other eye conditions. o Avoid driving or operating machinery if you experience blurred vision or visual disturbances.

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Eye Care

Paricar (Pilocarpine Nitrate 2% Eye Drops) is a miotic ophthalmic solution primarily used to manage certain eye conditions by reducing intraocular pressure. ________________________________________ 🔍 Uses 1. Treatment of Glaucoma and Ocular Hypertension Pilocarpine Nitrate 2% is employed to lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. It facilitates the drainage of aqueous humor from the eye, thereby reducing IOP and helping prevent vision loss and nerve damage. 2. Management of Acute Angle-Closure Glaucoma In acute angle-closure glaucoma, Pilocarpine Nitrate 2% may be used to constrict the pupil, facilitating the opening of the angle between the iris and cornea, which helps in reducing IOP. 3. Induction of Miosis Pilocarpine Nitrate 2% is utilized to induce miosis (pupil constriction) during certain eye surgeries or to reverse the effects of drugs used to dilate the pupil during eye examinations. ________________________________________ 💧 Dosage and Administration • General Dosage: Instill one drop into the affected eye(s) 1 to 4 times daily, as directed by your healthcare provider. • Application Method: 1. Wash your hands thoroughly before use. 2. Tilt your head back slightly and pull down the lower eyelid to form a pouch. 3. Hold the dropper above the eye and instill the prescribed number of drops. 4. Close the eye gently and apply gentle pressure to the inner corner of the eye for 1 to 2 minutes to prevent the medication from draining away. 5. Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. ________________________________________ ⚠️ Safety and Side Effects • Common Side Effects: o Temporary eye discomfort, such as stinging or burning sensations. o Blurred vision. o Headache. • Visual disturbances. • Serious Side Effects: o Although rare, systemic absorption may lead to increased blood pressure, headache, or dizziness. • Precautions: o Consult your doctor if you are pregnant or breastfeeding, as the safety of Pilocarpine Nitrate 2% during these periods is not well-established. o Use with caution if you have a history of retinal diseases or other eye conditions. o Avoid driving or operating machinery if you experience blurred vision or visual disturbances.

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Eye Care

Paripher Eye Drop contains Phenylephrine Hydrochloride 10% and is primarily used in ophthalmology for its mydriatic (pupil-dilating) effects. This formulation is typically employed in clinical settings and is available by prescription.** ________________________________________ 🔍 Uses 1. Pupil Dilation (Mydriasis): Paripher is utilized to dilate the pupil during eye examinations and surgical procedures, allowing for a clearer view of the retina and other internal structures. 2. Treatment of Eye Redness and Irritation: As a decongestant, it constricts blood vessels in the eye, reducing redness and irritation caused by allergies or other factors. 3. Management of Uveitis: Phenylephrine's vasoconstrictive properties aid in managing inflammation associated with uveitis by decreasing blood flow to the affected area. 4. Adjunct in Nasal Decongestion: Though primarily an eye drop, Paripher's active ingredient is also utilized in nasal decongestants to relieve symptoms of the common cold. ________________________________________ ⚠️ Usage Instructions • Application: Instill the prescribed number of drops into the lower conjunctival sac of the eye. • Contact Lenses: Remove soft contact lenses before application and wait at least 10–15 minutes before reinsertion. • Avoid Contamination: Do not touch the dropper tip to any surface, including the eye, to prevent contamination. • Multiple Medications: If using other eye medications, wait at least 10 minutes before applying them to avoid dilution. ________________________________________ ⚠️ Safety and Side Effects • Common Side Effects: Temporary eye discomfort, such as stinging or burning sensations. • Serious Side Effects: Although rare, systemic absorption may lead to increased blood pressure, headache, or dizziness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding.

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Eye Care

Paripher Eye Drop is a pharmaceutical product containing Phenylephrine Hydrochloride 5%. It is primarily used in ophthalmology for various diagnostic and therapeutic purposes. ________________________________________ 🔍 Uses of Paripher Eye Drop 1. Pupil Dilation (Mydriasis): Paripher is commonly employed to dilate the pupil during eye examinations and surgical procedures, facilitating a clearer view of the retina and other internal structures. 2. Treatment of Eye Redness and Irritation: As a decongestant, it constricts blood vessels in the eye, reducing redness and irritation caused by allergies or other factors. 3. Management of Uveitis: Phenylephrine's vasoconstrictive properties aid in managing inflammation associated with uveitis by decreasing blood flow to the affected area. 4. Adjunct in Nasal Decongestion: Though primarily an eye drop, Paripher's active ingredient is also utilized in nasal decongestants to relieve symptoms of the common cold. ________________________________________ ⚠️ Usage Instructions • Application: Instill the prescribed number of drops into the lower conjunctival sac of the eye. • Contact Lenses: Remove soft contact lenses before application and wait at least 10–15 minutes before reinsertion. • Avoid Contamination: Do not touch the dropper tip to any surface, including the eye, to prevent contamination. • Multiple Medications: If using other eye medications, wait at least 10 minutes before applying them to avoid dilution. ________________________________________ ⚠️ Safety and Side Effects • Common Side Effects: Temporary eye discomfort, such as stinging or burning sensations. • Serious Side Effects: Although rare, systemic absorption may lead to increased blood pressure, headache, or dizziness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding.

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Eye Care

FZ-3 Eye-Ear Drops containing Fluconazole are primarily used to treat fungal infections of the eyes and ears. Fluconazole is an antifungal medication that works by inhibiting the growth of fungi. 🔹 Primary Uses Fungal Eye Infections (Ophthalmic Fungal Infections) Fluconazole in eye drop form is used to treat fungal infections of the eye, such as fungal keratitis or endophthalmitis, which can cause inflammation, pain, and potentially lead to vision loss if left untreated. Fungal Ear Infections (Otomycosis) FZ-3 can be used for treating fungal ear infections, also known as otomycosis, which is often caused by fungi like Aspergillus or Candida. Symptoms include itching, pain, and discharge from the ear canal. 🔹 How It Works Fluconazole is an antifungal agent that works by inhibiting the fungal enzyme lanosterol 14α-demethylase, which is involved in the synthesis of ergosterol, an essential component of the fungal cell membrane. By blocking this enzyme, fluconazole disrupts the fungal cell membrane, leading to fungal cell death or inhibition of growth. ⚠️ Common Side Effects Eye: Mild eye irritation or burning sensation upon application Blurred vision (temporary) Redness or stinging in the eyes Ear: Mild ear irritation Ear itching or discomfort after application Temporary hearing changes (rare) If any of these side effects persist or worsen, consult your healthcare provider. 🔹 Usage Tips Dosage: Typically, 1–2 drops are applied to the affected eye or ear 2–3 times daily, as prescribed by your doctor. Application Instructions: Wash your hands thoroughly before applying the drops. For the eyes: Tilt your head back and gently pull down the lower eyelid to form a pocket. Instill the prescribed number of drops and gently close your eye for a few seconds. For the ears: Tilt your head to one side, apply the drops into the ear canal, and gently massage the ear to help the drops penetrate. If you are using other medications for the eyes or ears, wait about 5 minutes between applying each medication. Contact Lenses: If you wear contact lenses, remove them before applying the drops to avoid any contamination. You can reinsert your lenses after 15 minutes. 🔹 Precautions Allergies: If you have a known allergy to fluconazole or other azole antifungals, do not use the drops. Pregnancy and Breastfeeding: Fluconazole should be used with caution in pregnancy, particularly during the first trimester. Always consult your doctor if you are pregnant or breastfeeding. Underlying Conditions: Inform your healthcare provider if you have any liver or kidney diseases, as these conditions may affect how the medication works in your body. Systemic Absorption: Although FZ-3 is used topically, there is a possibility of systemic absorption. Monitor for any systemic side effects, especially with prolonged use.

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Eye Care

Dorzopar Eye Drops containing Dorzolamide 2% are primarily used to lower intraocular pressure (IOP) in individuals with glaucoma or ocular hypertension (high eye pressure). Here's a detailed breakdown of its uses: 🔹 Primary Uses Open-Angle Glaucoma Dorzolamide is a carbonic anhydrase inhibitor that helps reduce the production of aqueous humor (the fluid inside the eye). By decreasing the amount of fluid produced, it lowers the intraocular pressure (IOP), which is important in treating open-angle glaucoma. Glaucoma is a condition where high eye pressure can damage the optic nerve and lead to vision loss. Ocular Hypertension Dorzopar is also used for the treatment of ocular hypertension, a condition in which the eye pressure is elevated but glaucoma has not yet developed. Lowering eye pressure helps prevent the progression to glaucoma. 🔹 How It Works Dorzolamide works by inhibiting the carbonic anhydrase enzyme in the eye. This enzyme is involved in the production of aqueous humor. By blocking this enzyme, Dorzolamide reduces the amount of fluid produced inside the eye, which in turn lowers the eye pressure. ⚠️ Common Side Effects Eye irritation, burning, or stinging upon application Blurred vision (temporary) Redness in the eyes or foreign body sensation Dry eyes or increased tear production Headaches or dizziness (in some cases) Taste disturbance (a bitter taste in the mouth) 🔹 Usage Tips Dosage: Typically, 1 drop in each affected eye, twice daily (morning and evening), or as prescribed by your healthcare provider. Application Instructions: Wash your hands thoroughly before applying the drops. Tilt your head back slightly and pull down your lower eyelid to form a small pocket. Place one drop in the pocket without touching the dropper tip to your eye. Gently close your eye and blink a few times to help spread the medication. If using other eye medications, wait 5–10 minutes between applications. Contact Lenses: Remove contact lenses before applying the drops and wait at least 15 minutes before reinserting them. 🔹 Precautions Kidney or Liver Problems: Since Dorzolamide is metabolized in the body, it should be used with caution in individuals with kidney or liver issues. Pregnancy and Breastfeeding: Consult your doctor before using this medication if you are pregnant or breastfeeding, as the safety of Dorzolamide during pregnancy or while breastfeeding has not been fully established. Eye Infections: Be cautious if you have an eye infection, as Dorzolamide may not be suitable for some active infections. Systemic Effects: While Dorzolamide is generally applied locally to the eye, some systemic absorption may occur, leading to side effects like metabolic acidosis (rare). It should be used cautiously in patients with a history of diabetes, kidney disease, or respiratory problems.

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Eye Care

Tropicamide Ophthalmic Solution USP 0.5% is a sterile, anticholinergic eye drop used primarily for diagnostic purposes in ophthalmology. ________________________________________ 🔍 Primary Uses 1. Pupillary Dilation (Mydriasis): Tropicamide 0.5% is employed to dilate the pupil, facilitating detailed examination of the retina, optic nerve, and other internal eye structures during procedures like fundoscopy and slit-lamp assessments. 2. Cycloplegia: It temporarily paralyzes the ciliary muscle, preventing accommodation (focusing), which is useful in refractive error assessments. 3. Management of Uveitis: Tropicamide 0.5% is utilized in treating conditions like acute and subacute iridocyclitis, chronic iridocyclitis, and to prevent adhesions and disruptions of the iris and ciliary body. ________________________________________ ⚠️ Side Effects While generally well-tolerated, potential side effects may include: • Temporary stinging or burning sensation upon instillation • Blurred vision • Sensitivity to light (photophobia) • Dry mouth • Headache • Nausea or vomiting • Pale skin • Central nervous system disturbances, including agitation or confusion, especially in pediatric patients ________________________________________ 🧪 Usage Instructions • Administration: Instill one or two drops into the affected eye(s) as directed by your healthcare provider. • Contact Lenses: Remove contact lenses before application. • Hygiene: Avoid touching the dropper tip to any surface to prevent contamination. • Post-application: Apply gentle pressure to the inner corner of the eye for 1–3 minutes to minimize systemic absorption. ________________________________________ ⚠️ Precautions • Driving and Operating Machinery: Avoid engaging in activities requiring clear vision, such as driving, until the effects of the medication have worn off. • Pediatric Use: Use with caution in children, as anticholinergic drugs may cause CNS disturbances. • Pregnancy and Breastfeeding: Consult your healthcare provider before use during pregnancy or while breastfeeding.

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Eye Care

Biotrav-T (Travoprost and Timolol Maleate) Ophthalmic Solution is a prescription eye drop used to manage elevated intraocular pressure (IOP) in individuals with open-angle glaucoma or ocular hypertension. It combines two medications—travoprost (a prostaglandin analog) and timolol maleate (a non-selective beta-blocker)—to reduce IOP through complementary mechanisms. ________________________________________ ✅ Primary Uses • Open-Angle Glaucoma: A common form of glaucoma characterized by gradual loss of vision due to increased IOP. • Ocular Hypertension: Elevated IOP without optic nerve damage, which can lead to glaucoma if untreated. ________________________________________ 💊 Dosage and Administration • Recommended Dosage: Instill one drop into the affected eye(s) once daily, preferably in the evening. • Application Tips: o Wash hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: o Hypersensitivity to any component of the formulation. o Active or suspected ocular infections. o History of hypersensitivity to beta-blockers. • Cautions: o Use with caution in patients with cardiovascular or pulmonary diseases, as timolol may exacerbate conditions like asthma, bradycardia, or heart block. o Monitor for potential systemic absorption effects, including hypotension or bradycardia. o Consult a healthcare provider before use if pregnant, planning to become pregnant, or breastfeeding. ________________________________________

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Hepatitis Medicine

Tafnat Tablet is used in the treatment of HIV infection and chronic hepatitis B virus (HBV) infection. It prevents the multiplication of viruses in human cells. This stops the virus from producing new viruses and clears up your infection. Tafnat Tablet should be used in the dose and duration as advised by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Take it with food, as this increases the absorption of the medicine into the body. It is important to keep taking them until your doctor tells you it is safe to stop. Common side effects of this medicine include headache, diarrhea, nausea, joint pain, abdominal pain, and indigestion. Please consult your doctor if it persists for a longer duration. These are usually not serious but tell your doctor if they bother you or do not go away. Rarely, some people may experience a skin reaction or liver damage. Your doctor will closely monitor you for these in the initial period of treatment.

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