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'osteonecrosis death'

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Hepatitis Medicine

Tavin 300mg tablet tablet consists of the active substance called Tenofovir Disoproxil Fumarate, which belongs to the class of antiretroviral or antiviral medicine. This medicine treats HIV (human immunodeficiency virus) and HBV (hepatitis B virus) infections. It is a nucleotide reverse transcriptase inhibitor (NRTI) and works by inhibiting the enzymes (HIV reverse transcriptase; hepatitis B DNA polymerase) that are important for virus replication. It should always take in combination with other medicines to treat HIV infection. This tablet is suitable for the adult and adolescents aged from 12 to 18 years. For HIV, this medicine is given to adolescents who have already been medicated with other HIV medicines which are no longer fully effective due to resistance or have caused side effects. This tablet is not been studied in patients over 65 years of age. Do not consume this drug if you have experienced hypersensitivity reactions to Tenofovir disoproxil fumarate or any of its ingredients. During the Tavin 300mg tablet tablet treatment, your doctor may periodically monitor your blood counts, bone mineral density, liver and kidney parameters to prevent serious complications. Report to your doctor if you have had a history of heart failure, pancreatitis, bone disease (osteonecrosis - the death of bone tissue), fractures, liver (chronic hepatitis B or C), or kidney problems.

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HIV/AIDS

INTRODUCTION ABALAM 600/300 is a combination of Abacavir and Lamivudine which belongs to the group of medicines called Anti-viral agents. It is used in the management of HIV infection in adults, adolescents and in children (weighing above 25 kgs). HIV (human immunodeficiency virus) infection is a viral infection that damages our immune system and weakens our body’s ability to fight against various infections. Both abacavir and lamivudine are nucleoside reverse transcriptase inhibitors. They work by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. This prevents further multiplication of viral cells within the body. Also, they can improve immunity in the affected patients by increasing the number of certain types of white blood cells (CD4) in the body which is required to fight against various infections. ABALAM 600/300 cannot not manage HIV infection completely. It can reduce only the number of viral cells present in the body and maintains them at a lower level. During management with ABALAM 600/300 your doctor will closely monitor your body weight, blood cholesterol levels and blood sugar levels to reduce the risk of unwanted side effects. Do not take ABALAM 600/300 if you are allergic to abacavir or lamivudine. Before taking ABALAM 600/300 inform your doctor if you have diabetes or any liver (hepatitis C or B infection), kidney or heart problems. If you are already taking ABALAM 600/300 to manage hepatitis B or C infection, do not stop taking it without consulting your doctor. Even if you take ABALAM 600/300, it is important for you to follow certain measures to prevent the spread of infections to the other people (such as avoid having unprotected sexual intercourse or sharing needles or personal items like toothbrush, razors etc with other people). ABALAM 600/300 is not recommended for use in pregnant or breastfeeding women. The most common side effects of taking ABALAM 600/300 are difficulty in sleeping, increased signs of infections, nausea, stomach pain, headache, or dizziness. Consult your doctor if any of these side effects worsens. Also inform your doctor immediately if you experience severe fever with extreme tiredness, sudden changes in body weight or severe stomach pain along with dark urine after taking ABALAM 600/300. USES OF ABALAM 600/300 Manages HIV infection in adults, adolescents and in children (weighing above 25 kgs) HOW ABALAM 600/300 WORKS ABALAM 600/300 is an anti-retroviral medicine. It controls the multiplication of viral cell within the body, by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. It can also improve immunity in the affected patients by increasing the number of certain types of white blood cells (CD4) in the body which is required to fight against various infections. DIRECTIONS FOR USE Take ABALAM 600/300 as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. ABALAM 600/300 can be taken with or without meals. Your doctor will decide the correct dose and for how long ABALAM 600/300 must be taken depending upon your age, body weight and severity of the infection. Do not stop taking ABALAM 600/300 without consulting your doctor as it may reduce its effectiveness. SIDE EFFECTS OF ABALAM 600/300 COMMON difficulty in sleeping feeling depressed headache, tiredness, dizziness nausea, diarrhoea fever, skin rash stomach pain loss of appetite irritated or runny nose hair loss UNCOMMON decrease in RBC, WBC, and platelets RARE Stop taking ABALAM 600/300 and contact your doctor immediately if you experience any of the following side effects: signs of allergic reactions (such as skin rash, fever, accompanied with sore throat, cough, nausea, vomiting, stomach pain, diarrhea, tiredness, joint pain, muscle pain, swelling of the neck, difficulty in breathing, mouth ulcers, occasional headaches, inflammation of the eye, low blood pressure, sense of tingling or numbness of hands or feet) pure red cell aplasia (failure of bone marrow to produce new red blood cells) signs of infections (such as fever, headache, stomach-ache, breathing difficulty) signs of auto-immune disorders (such as rapid or irregular heartbeat, tremor, hyperactivity, general weakness) signs of osteonecrosis (death of bone cells causing joint stiffness, pain in the hip, knee or shoulder and difficulty in moving) signs of liver problems (such as yellowing of the skin and whites of the eye, dark urine, light-coloured stools, loss of appetite, nausea, pain, tenderness on the right side of stomach) heart attack changes in body fat (such as increase fat in the shoulder and neck (buffalo hump), breast, and in the middle body or fat loss from the legs, arms, or face)

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Cats and Dogs

A healthy liver produces glutathione, a natural anti-oxidant that neutralises free radicals. However, during oxidative stress, when there is an imbalance between free radicals and the levels of antioxidants in the body, there is injury and damage to liver cells. Lisybin is an advanced liver support formula that combines the anti-oxidant properties of 2 potent ingredients – S-Adenosyl Methionine & Silybin as Silybin – Phosphatidyl choline complex (SPC complex) that help in increasing glutathione levels. LISYBIN is indicated in the maintenance, improvement and protection of liver function in dogs and cats. Lisybin increases liver glutathione levels which helps in cell repair and regeneration and protecting liver cells from cell death. LISYBIN is formulated with World’s best ingredients and offers dosing convenience and accuracy

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Eye Care

Tobi-D (Tobramycin with Dexamethasone) Eye Drops is a prescription ophthalmic solution combining an antibiotic and a corticosteroid to treat specific bacterial eye infections accompanied by inflammation. ________________________________________ ✅ Primary Uses Tobi-D is primarily used for: • Bacterial Conjunctivitis: Infection of the conjunctiva (the membrane covering the white part of the eye and the inner surface of the eyelids). • Keratitis: Infection of the cornea. • Post-surgical Infections: Prophylactic treatment or management of infections following eye surgeries. It addresses both the infection and the inflammation associated with these conditions. ________________________________________ 💊 Dosage and Administration • Standard Dosage: Instill 1–2 drops into the affected eye(s) every 4–6 hours, or as directed by your healthcare provider. • Application Tips: o Wash your hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. ________________________________________ ⚠️ Contraindications and Cautions • Contraindications: o Hypersensitivity to tobramycin, dexamethasone, or any component of the formulation. o Active viral infections of the eye, such as herpes simplex keratitis. o Untreated fungal or mycobacterial infections of the eye. • Cautions: o Use with caution in patients with a history of glaucoma, as corticosteroids can increase intraocular pressure. o Prolonged use may lead to cataract formation or secondary ocular infections. o Consult your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. ________________________________________ 🧪 Mechanism of Action • Tobramycin: An aminoglycoside antibiotic that inhibits bacterial protein synthesis, leading to bacterial cell death. • Dexamethasone: A corticosteroid that reduces inflammation by inhibiting the release of inflammatory mediators. Together, these components address both the infection and the inflammation associated with certain eye conditions.

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General Medicine

Pipracan 4.5 Injection is a combination antibiotic medication containing Piperacillin (4 g) and Tazobactam (0.5 g). This formulation is used to treat a wide range of serious bacterial infections that may not respond to other antibiotics. ________________________________________ 🔹 Common Uses Pipracan 4.5 Injection is prescribed for: • Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) • Urinary tract infections (UTIs) • Intra-abdominal infections (e.g., peritonitis) • Skin and soft tissue infections, including diabetic foot infections • Gynecological infections, such as uterine infections • Bone and joint infections • Bloodstream infections (bacteremia) It is also used for prophylactic treatment in surgical procedures to prevent infections. ________________________________________ 🔹 How It Works • Piperacillin is a broad-spectrum penicillin antibiotic that inhibits bacterial cell wall synthesis, leading to bacterial cell death. • Tazobactam is a beta-lactamase inhibitor that protects piperacillin from degradation by beta-lactamase enzymes produced by certain bacteria, thereby enhancing its efficacy. This combination allows Pipracan 4.5 to target a wide array of bacteria, including those resistant to other antibiotics. ________________________________________ 🔹 Administration Pipracan 4.5 Injection is administered intravenously by a healthcare professional. The dosage and duration of treatment depend on the type and severity of the infection, as well as the patient's medical condition. Self-administration is not recommended. ________________________________________ 🔹 Side Effects Common side effects may include: • Nausea or vomiting • Diarrhea • Rash or itching • Pain, redness, or swelling at the injection site Serious side effects are rare but can include allergic reactions, liver enzyme abnormalities, or blood disorders. Seek immediate medical attention if you experience symptoms like difficulty breathing, swelling of the face or throat, or unusual bruising or bleeding. ________________________________________ 🔹 Precautions Before using Pipracan 4.5 Injection, inform your doctor if you have: Allergies to penicillins or beta-lactam antibiotics • Kidney or liver disease • A history of gastrointestinal diseases, such as colitis • Bleeding disorders • Undergoing dialysisUse during pregnancy and breastfeeding should be discussed with your healthcare provider. The medication should only be used if the potential benefits justify the potential risks.

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Heart Disorder

Duron Injection Salt: Amiodarone (150mg) Description Duron 150mg Injection is used to treat various types of serious irregular heartbeat (arrhythmia) such as fibrillation and tachycardia (increased heart rate). It is an anti-arrhythmic type of medicine which rapidly restores your heart to a steady and regular rhythm. Duron 150mg Injection is used to treat various types of serious irregular heartbeat (arrhythmia) such as fibrillation and tachycardia (increased heart rate). It is an anti-arrhythmic type of medicine which rapidly restores your heart to a steady and regular rhythm. Duron 150mg Injection is given by a slow drip (infusion) into a vein under the supervision of a doctor. Continuous monitoring of blood pressure and heart rate may be needed while this medicine is administered. It is important that you keep having the injections until your doctor decides it is safe to stop them. After this, your doctor may prescribe tablets instead of the injection. If you stop taking this medicine, you may get dangerous uneven heartbeats, which can be life-threatening. The most common side effects of this medicine include decreased blood pressure (hypotension), decreased heart rate (bradycardia), blurred vision, and application site reaction(pain, itching, and skin redness). This medicine can also cause problems with your liver, lungs, nerves, and thyroid gland. Ask your doctor what signs to look out for and report any symptoms you have. This medicine takes a long time to get cleared from the body. You may continue to have side effects after you stop using it. Ask your doctor about ways to prevent or reduce them Benefits 1. In Arrhythmia: Duron 150mg Injection belongs to a group of medicines called anti-arrhythmics. It works by blocking abnormal electrical signals in the heart. This helps control the uneven beating of your heart and helps it to beat normally. It is normally only given by injection in a hospital when a fast response is needed or when tablets have not worked or cannot be given. This medicine thus prevents serious health problems that can sometimes be fatal and reduces your risk of death. Side Effects Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Common side effects of Duron: - Decreased blood pressure - Slow heart rate - Blurred vision - Application site reactions (burning, irritation, itching and redness)

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Heart Disorder

Icikinase 1.5MIU Injection Marketer Abbott SALT COMPOSITION Streptokinase (1500000IU) Storage Store in a refrigerator (2 - 8°C). Do not freeze. Uses of Icikinase Injection Heart attack Pulmonary embolism Product introduction Icikinase 1.5MIU Injection is a medicine used to break down harmful blood clots that have formed in the blood vessels. It is used to treat patients who have suffered a recent heart attack. It is also used in treating conditions such as pulmonary embolism and stroke. Icikinase 1.5MIU Injection is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. The doctor may closely monitor your condition until you become stable. Use of this medicine may cause injection site bleeding, nausea, allergic reaction, and a decrease in blood pressure. It may increase your risk of bleeding also. Your doctor will explain the benefits and risks associated with this medicine before it is administered. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection. This medicine is used with caution for some people. Thus, you must inform the doctor if you are suffering from any bleeding disorder, kidney, or liver disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly. Side effects of Icikinase Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Icikinase Allergic reaction Nausea Injection site bleeding Decrease in blood pressure How to use Icikinase Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Icikinase Injection works Icikinase 1.5MIU Injection works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected tissue, thereby preventing tissue death and improving outcomes. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Icikinase 1.5MIU Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Icikinase 1.5MIU Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. warnings Breast feeding CONSULT YOUR DOCTOR Information regarding the use of Icikinase 1.5MIU Injection during breastfeeding is not available. Please consult your doctor. warnings Driving NOT RELEVANT Not relevant, as Icikinase 1.5MIU Injection is intended for use in hospitalised patients. warnings Kidney SAFE IF PRESCRIBED Icikinase 1.5MIU Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Icikinase 1.5MIU Injection may not be needed in these patients. Please consult your doctor. Use of Icikinase 1.5MIU Injection is not recommended in patients with severe kidney disease. warnings Liver CAUTION Icikinase 1.5MIU Injection should be used with caution in patients with severe liver disease. Dose adjustment of Icikinase 1.5MIU Injection may be needed. Please consult your doctor. What if you forget to take Icikinase Injection? If you miss a dose of Icikinase 1.5MIU Injection, please consult your doctor.n

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Heart Disorder

U Frag 5000IU Injection Marketer Bharat Serums & Vaccines Ltd SALT COMPOSITION Urokinase (5000IU) Storage Store in a refrigerator (2 - 8°C). Do not freeze. Uses of U Frag Injection Heart attack Pulmonary embolism Product introduction U Frag 5000IU Injection is a medicine used to break down harmful blood clots that have formed in the blood vessels. It is used to treat patients who have suffered a recent heart attack. It is also used in treating conditions such as pulmonary embolism and stroke. U Frag 5000IU Injection is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. The doctor may closely monitor your condition until you become stable. Use of this medicine may cause nausea, vomiting, injection site bleeding, allergic reaction, and a decrease in blood pressure. It may increase your risk of bleeding also. Your doctor will explain the benefits and risks associated with this medicine before it is administered. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection. This medicine is used with caution for some people. Thus, you must inform the doctor if you are suffering from any bleeding disorder, kidney, or liver disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly. Side effects of U Frag Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of U Frag Allergic reaction Nausea Vomiting Injection site bleeding Decreased blood pressure How to use U Frag Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How U Frag Injection works U Frag 5000IU Injection works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected tissue, thereby preventing tissue death and improving outcomes. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with U Frag 5000IU Injection. Please consult your doctor. warnings Pregnancy SAFE IF PRESCRIBED U Frag 5000IU Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies. warnings Breast feeding SAFE IF PRESCRIBED U Frag 5000IU Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. warnings Driving NOT RELEVANT Not relevant, as U Frag 5000IU Injection is intended for use in hospitalised patients. warnings Kidney SAFE IF PRESCRIBED U Frag 5000IU Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of U Frag 5000IU Injection may not be needed in these patients. Please consult your doctor. Use of U Frag 5000IU Injection is not recommended in patients with severe kidney disease. warnings Liver CAUTION U Frag 5000IU Injection should be used with caution in patients with liver disease. Dose adjustment of U Frag 5000IU Injection may be needed. Please consult your doctor.

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Heart Disorder

U Frag 500000IU Injection Marketer Bharat Serums & Vaccines Ltd SALT COMPOSITION Urokinase (500000IU) Storage Store in a refrigerator (2 - 8°C). Do not freeze. Uses of U Frag Injection Heart attack Pulmonary embolism Product introduction U Frag 500000IU Injection is a medicine used to break down harmful blood clots that have formed in the blood vessels. It is used to treat patients who have suffered a recent heart attack. It is also used in treating conditions such as pulmonary embolism and stroke. U Frag 500000IU Injection is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. The doctor may closely monitor your condition until you become stable. Use of this medicine may cause nausea, vomiting, injection site bleeding, allergic reaction, and a decrease in blood pressure. It may increase your risk of bleeding also. Your doctor will explain the benefits and risks associated with this medicine before it is administered. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection. This medicine is used with caution for some people. Thus, you must inform the doctor if you are suffering from any bleeding disorder, kidney, or liver disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly. Side effects of U Frag Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of U Frag Allergic reaction Nausea Vomiting Injection site bleeding Decreased blood pressure How to use U Frag Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How U Frag Injection works U Frag 500000IU Injection works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected tissue, thereby preventing tissue death and improving outcomes. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with U Frag 500000IU Injection. Please consult your doctor. warnings Pregnancy SAFE IF PRESCRIBED U Frag 500000IU Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies. warnings Breast feeding SAFE IF PRESCRIBED U Frag 500000IU Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. warnings Driving NOT RELEVANT Not relevant, as U Frag 500000IU Injection is intended for use in hospitalised patients. warnings Kidney SAFE IF PRESCRIBED U Frag 500000IU Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of U Frag 500000IU Injection may not be needed in these patients. Please consult your doctor. Use of U Frag 500000IU Injection is not recommended in patients with severe kidney disease. warnings Liver CAUTION U Frag 500000IU Injection should be used with caution in patients with liver disease. Dose adjustment of U Frag 500000IU Injection may be needed. Please consult your doctor.

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