Washington
+919359902383

'muscarinic antagonist'

Items tagged with 'muscarinic antagonist'

product image
Eye Care

Cyclopentolate Hydrochloride & Dexamethasone Ophthalmic Solution USP (Cyclopan-D) is a combination eye drop used for specific eye conditions involving both inflammation and pupil dilation. Here's a breakdown of its uses: 🔹 Primary Uses Treatment of Uveitis (Inflammation of the Uvea) Cyclopentolate dilates the pupil, helping to alleviate pain associated with inflammation in the eye. Dexamethasone, a corticosteroid, reduces inflammation. Post-Operative Inflammation and Pain Relief After eye surgeries (e.g., cataract surgery), this combination helps manage inflammation and promotes healing. Pupil Dilation for Diagnostic Purposes Used before certain eye exams or surgeries to dilate the pupil for better visibility and assessment of the eye's interior. 🔹 How It Works Cyclopentolate Hydrochloride: A muscarinic antagonist that causes pupil dilation (mydriasis) by blocking the action of acetylcholine on the muscles in the iris, which normally constrict the pupil. Dexamethasone: A potent corticosteroid that reduces inflammation by suppressing the immune response and inhibiting the production of inflammatory chemicals. Together, they reduce pain, control inflammation, and help improve vision in certain conditions by dilating the pupil and promoting healing. ⚠️ Common Side Effects Temporary blurred vision (due to pupil dilation) Stinging or burning after application Increased intraocular pressure (with prolonged use of dexamethasone) Sensitivity to light (from dilated pupil) Dryness or irritation in the eye 🔹 Usage Instructions Frequency: Follow your doctor's prescribed schedule, typically 1–2 drops in the affected eye(s) up to 4 times a day (especially for inflammation). For pupil dilation, it's usually a single application before the procedure or exam. Application Tips: Wash your hands before use. Tilt your head back and gently pull down the lower eyelid to form a pocket. Drop the medication into the pocket without touching the dropper to the eye. Close your eye gently and blink to spread the solution. If you have multiple eye drops to use, wait at least 5–10 minutes between applications. Contact Lenses: Remove contact lenses before using this drop and wait at least 15 minutes before reinserting. 🔹 Precautions Long-term Use: Dexamethasone can increase intraocular pressure and lead to glaucoma or cataract formation with prolonged use, so it should be used cautiously. Allergic Reactions: Inform your doctor if you're allergic to steroids, anticholinergic drugs, or any ingredients in this eye drop. Pregnancy and Breastfeeding: Consult with a healthcare provider before use if you are pregnant or breastfeeding.

Send Message
product image
General Medicine

Atrocan Injection is a medication containing Atropine Sulphate (0.6 mg), manufactured by American Remedies Ltd. It is primarily used in medical settings for various purposes: 🩺 Uses of Atrocan Injection 1. Treatment of Bradycardia: Atrocan is administered to manage bradycardia (slow heart rate), helping to restore normal heart rhythm during cardiac arrest situations. 2. Preoperative Medication: It is used before general anesthesia to reduce salivation and mucus secretions in the respiratory tract, facilitating smoother surgical procedures. 3. Antidote for Poisoning: Atrocan serves as an antidote for poisoning caused by organophosphate insecticides, nerve agents, or certain types of mushrooms. 4. Reversal of Muscle Relaxant Effects: In combination with other medications, Atrocan is used to reverse the effects of muscle relaxants during surgeries. 💊 Mechanism of Action Atropine, the active ingredient in Atrocan, is a muscarinic antagonist. It works by blocking the action of acetylcholine, a neurotransmitter, on muscarinic receptors. This leads to increased heart rate, reduced salivation, and decreased bronchial secretions. ⚠️ Side Effects Common side effects may include: • Dry mouth • Blurred vision • Increased heart rate • Flushing • Dizziness or confusion • Nausea or vomiting These side effects are generally mild and transient. If they persist or worsen, consult your healthcare provider. ⚠️ Precautions Before using Atrocan Injection, inform your doctor if you: • Have a history of allergies to atropine or other anticholinergic medications. • Suffer from glaucoma, urinary retention, or gastrointestinal disorders. • Are pregnant, planning to become pregnant, or breastfeeding. • Are taking other medications, including over-the-counter drugs and supplements.

Send Message
product image
Eye Care

Timipar (Timolol Maleate 0.5%) Ophthalmic Solution is a prescription eye drop used to manage elevated intraocular pressure (IOP) in conditions such as open-angle glaucoma and ocular hypertension. By reducing the production of fluid within the eye, it helps lower IOP, thereby reducing the risk of optic nerve damage and potential vision loss. ________________________________________ ✅ Primary Uses • Open-Angle Glaucoma: A common form of glaucoma where the drainage angle in the eye remains open, but the trabecular meshwork is partially blocked, leading to increased IOP. • Ocular Hypertension: A condition characterized by higher-than-normal IOP without any signs of glaucoma damage. ________________________________________ 💊 Dosage and Administration • Typical Dosage: Instill one drop of the 0.5% solution into the affected eye(s) twice daily. • Application Tips: o Wash your hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. o After instilling the drop, gently press the corner of your eye (near the nose) for 1–2 minutes to prevent the medication from draining out. ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: o Hypersensitivity to any component of the formulation. o Bronchial asthma or a history of bronchial asthma. o Severe chronic obstructive pulmonary disease (COPD). o Sinus bradycardia, second- or third-degree atrioventricular block, overt cardiac failure, or cardiogenic shock. • Cautions: o Use with caution in patients with a history of heart disease, diabetes, or thyroid disorders, as beta-blockers can mask symptoms of hypoglycemia and hyperthyroidism. o Monitor for potential additive effects when used with other systemic beta-blockers. ________________________________________ 🧪 Mechanism of Action Timolol is a non-selective beta-adrenergic antagonist (beta-blocker) that reduces aqueous humor production in the eye, leading to a decrease in IOP. Its onset of action is typically within 20 minutes, with effects lasting up to 24 hours.

Send Message
product image
Eye Care

Timipar (Timolol Maleate 0.25%) eye drops are a prescription medication primarily used to manage elevated intraocular pressure (IOP) associated with conditions like open-angle glaucoma and ocular hypertension. By reducing the production of aqueous humor, the fluid inside the eye, Timolol helps lower IOP, thereby reducing the risk of optic nerve damage and potential vision loss . ________________________________________ ✅ Primary Uses • Open-Angle Glaucoma: A common type of glaucoma where the drainage angle in the eye remains open, but the trabecular meshwork is partially blocked, leading to increased IOP. • Ocular Hypertension: A condition characterized by higher-than-normal IOP without any signs of glaucoma damage. ________________________________________ 💊 Dosage and Administration • Typical Dosage: Instill one drop of the 0.25% solution into the affected eye(s) once or twice daily, as directed by your healthcare provider. • Application Tips: o Wash your hands before use. o Avoid touching the dropper tip to any surface, including the eye, to prevent contamination. o If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them . ________________________________________ ⚠️ Precautions and Contraindications • Contraindications: o Hypersensitivity to any component of the formulation. o Bronchial asthma or a history of bronchial asthma. o Severe chronic obstructive pulmonary disease (COPD). • Sinus bradycardia, second- or third-degree atrioventricular block, overt cardiac failure, or cardiogenic shock . • Cautions: o Use with caution in patients with a history of heart disease, diabetes, or thyroid disorders, as beta-blockers can mask symptoms of hypoglycemia and hyperthyroidism. o Monitor for potential additive effects when used with other systemic beta-blockers . ________________________________________ 🧪 Mechanism of Action Timolol is a non-selective beta-adrenergic antagonist (beta-blocker) that reduces aqueous humor production in the eye, leading to a decrease in IOP. Its onset of action is typically within 20 minutes, with effects lasting up to 24 hours .

Send Message
product image
General Medicine

Ondican 2 Injection is a brand of Ondansetron 2 mg/2 mL Injection, manufactured by American Remedies. Ondansetron is a 5-HT₃ receptor antagonist commonly used as an antiemetic to prevent and treat nausea and vomiting associated with various medical conditions. ________________________________________ ✅ Primary Uses Ondican 2 Injection is indicated for: • Chemotherapy-Induced Nausea and Vomiting (CINV): To prevent and treat nausea and vomiting caused by cancer chemotherapy. Radiotherapy-Induced Nausea and Vomiting (RINV): To prevent and treat nausea and vomiting associated with radiation therapy. Postoperative Nausea and Vomiting (PONV): To prevent and treat nausea and vomiting following surgical procedures. These indications are supported by clinical guidelines and pharmacological references. ________________________________________ ⚙️ Mechanism of Action Ondansetron works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting. It specifically inhibits serotonin receptors in the chemoreceptor trigger zone (CTZ) in the brain, thereby preventing the sensation of nausea and the act of vomiting. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Allergy: Do not use if allergic to ondansetron or other 5-HT₃ receptor antagonists. • Cardiac Conditions: Use with caution in patients with a history of heart problems, as ondansetron may affect heart rhythm. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Headache • Constipation • DizzinessFatigue Serious Side Effects: • Allergic reactions (rash, itching, swelling) Severe dizziness or fainting • Irregular heartbeat Seek immediate medical attention if any serious side effects occur.

Send Message
product image
Anti Emetic

What is Ondem 8mg Ondem 8mg is an antiemetic medication used to treat nausea and vomiting caused by illnesses like chemotherapy, radiation therapy, or surgery. The active component is Ondansetron, a Serotonin Receptor Antagonist. Ondansetron reduces nausea and vomiting by inhibiting Serotonin receptors in the gastrointestinal tract and brain. Ondem is widely administered for people receiving Cancer treatment or recovering from surgery, where nausea and vomiting are prevalent side effects. The medicine should be taken with caution in those with a history of cardiac issues, especially those with an electrolyte imbalance because it might cause QT prolongation (a kind of heart Arrhythmia). Furthermore, Ondem should not be used with some medications, such as Apomorphine (which is used to treat Parkinson's disease), due to the possibility of severe Hypotension (low blood pressure) and trouble maintaining consciousness. Patients should tell their doctor if they are taking any additional medicines, particularly those that impact the heart, liver, or Serotonin levels (e.g., antidepressants) because these interactions might increase the risk of side effects. Alkem Laboratories Ltd. primarily manufactures this medicine in a GMP-complaint facility. What are the benefits of Ondem 8mg Ondansetron in Ondem 8mg reduces nausea and vomiting by targeting a neurotransmitter in your body called Serotonin. Serotonin can cause nausea and vomiting, particularly in cancer treatment, following surgery, or even during pregnancy. Ondem inhibits Serotonin activity by binding to specific receptors in the brain's chemoreceptor trigger zone (CTZ), which regulates nausea and vomiting. The medication efficiently reduces nausea and the urge to vomit by preventing Serotonin from binding to these receptors. The medicine is quickly absorbed in the body, reaching its maximum concentration in around 1.5 hours. How to take Ondem 8mg Take Ondem 8mg tablets after consulting your doctor. Some general usage instructions include: The medicine is usually taken 1 hour before the treatment or as your doctor suggests. Swallow the tablet whole with water. Never crush or chew it. It can be taken with or without food. Follow the prescribed dose precisely as directed by your healthcare provider. What are the side effects of Ondem 8mg tablets Ondem 8 mg side effects include: Fatigue Headache Upset stomach Diarrhea These side effects are usually mild and temporary and tend to disappear as your body gets used to the medication. If any of these side effects continue or start to bother you, it's important to contact your healthcare provider without delay. Safety Advice Liver problemsLiver disease There is insufficient data regarding the use of Ondem 8mg in individuals with liver disease. It's crucial to get guidance from your healthcare expert before using this medication. CardiovascularKidney impairment The medication is usually safe for kidney patients when taken as advised. However, it is best to take a doctor’s advice before taking the pill. PregnancyPregnant and breastfeeding women There is limited information on the safety of Ondem tablets during pregnancy and breastfeeding. It's advisable to contact your doctor for personalized advice before using this medication in these situations. wineAvoid Alcohol should be avoided while taking Ondem, as it may worsen side effects. However, for overall health, it is not recommended to drink alcohol. Avoid taking the pill if you are allergic to Ondansartan or other ingredients.

Send Message

Still searching for
muscarinic antagonist?