Introduction to Xapavir 50mg Tablet Xapavir 50mg Tablet is an antiviral drug belonging to the Integrase strand transfer inhibitor category, containing the active ingredient Dolutegravir. It is used to treat human immunodeficiency virus (HIV) infection. HIV infection is mainly spread by sexual contact with anyone who has the infection or by transfer of infected blood (by sharing injection needles). This drug must be taken with other medicines used to treat HIV infection. This drug is contraindicated in individuals with liver disease. Due to the higher concentration, caution should be taken when administering the drug to individuals with liver impairment. The dosage of this drug may need to be adjusted by your doctor, or it may need to be used with extra monitoring in these individuals to ensure its safety and efficacy. During the early stages of HIV treatment, some patients may experience an inflammatory response to opportunistic infections. This condition, immune reconstitution syndrome, can occur after starting the drug or other antiretroviral therapies. Knowing this possibility and monitoring for any signs of worsening infections or inflammatory symptoms is necessary. Inform your healthcare provider if the symptoms concern you or persist longer than usual. It is necessary for healthcare professionals to carefully monitor patients taking this drug for any signs or symptoms of skin or hypersensitivity reactions, such as rash, blistering, or mucosal lesions. If a severe reaction is suspected, this medicine should be discontinued immediately, and appropriate medical treatment can be initiated. Patients are also advised to report any skin or hypersensitivity reactions to their healthcare provider and to seek medical emergency immediately if they experience any symptoms of a severe reaction. Tell your doctor immediately about all the medications you have been taking recently, including herbal and supplements, before taking this drug. Uses of Xapavir 50mg Tablet Human Immunodeficiency Virus (HIV) Therapeutic Effects of Xapavir 50mg Tablet Xapavir 50mg Tablet works by inhibiting the enzyme integrase, thereby reducing the virus in your body. It also increases a type of white blood cell called CD4 cells which help the body fight infection. Interaction of Xapavir 50mg Tablet with other drugs Inform your healthcare provider about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Xapavir 50mg Tablets and reduce effectiveness by causing undesirable side effects. More Information about Xapavir 50mg Tablet Store Xapavir 50mg Tablet at room temperature (15°to 25°C). Keep the Tablet out of reach of children and pets. How to consume Xapavir 50mg Tablet It is an orally available prescription drug. Your doctor will decide the dose and duration of the drug based on the disease condition and other factors. Always take Xapavir 50mg Tablet as prescribed by your doctor. Take the Tablet with or without food. Do not break, chew, or crush the Tablet. Swallow the whole Tablet with water. Safety Advices for Xapavir 50mg Tablet Image Not Available Pregnancy Suppose you are pregnant or planning for pregnancy during the treatment. Please consult your doctor before taking Xapavir 50mg Tablet. Image Not Available Breast Feeding Breastfeeding is not recommended in patients taking Xapavir 50mg Tablets because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment. Image Not Available Lungs It is unknown whether Xapavir 50mg Tablets can be prescribed for patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment. Image Not Available Liver Xapavir 50mg Tablet must be cautiously administered in patients with severe liver diseases. Dose adjustments are necessary for severe liver failure. Inform your doctor if you have liver problems before initiating the therapy Image Not Available Alcohol Consuming alcohol may affect the effectiveness of the Xapavir 50mg Tablet. It is highly advised to stop consuming alcohol if you take this medicine. Image Not Available Driving Driving vehicles or operating heavy machinery is unsafe after taking the Xapavir 50mg Tablet. It may cause dizziness and impair concentration. Side Effects of Xapavir 50mg Tablet Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Allergic reactions (swelling, high temperature) Infection, inflammation Inflammation of the liver; liver failure Joint pain Common Depression Abnormal dreams, insomnia Itching, rash Being sick Stomach discomfort, pain Headache Diarrhea Fatigue

Ichmune T contains Tacrolimus that helps to decrease itching, redness and inflammation associated with atopic dermatitis, Podo-dermatitis, Perianal fistula, Lupus and cutaneous vasculitis. Ichmune T is indicated for the lesions of atopic dermatitis, perianal fistula, podo-dermatitis, lupus and cutaneous vasculitis.

Gatipred belongs to a group of medications called ‘Antibiotics and Corticosteroids’ used to treat bacterial eye infections or eye discomfort, especially in patients who have undergone eye surgeries. It also decreases the risk of eye infections such as conjunctivitis (inflammation of the conjunctiva) and other inflammatory conditions of the eye (cornea, iris, and connective tissue) in postoperative patients. Gatipred is a combination of two medicines: Gatifloxacin and Prednisolone. Gatipred is an antibiotic that acts by interfering with the formation of essential proteins required for bacterial growth. Prednisolone is a steroid that reduces inflammation and symptoms associated with infection such as redness and irritation. It works by inhibiting the chemicals such as prostaglandins that cause inflammation. Gatifloxacin+prednisolone is available for external use only. You should take this medicine as prescribed by your doctor. The common side-effects of Gatipred are application site reactions such as redness, burning or stinging sensation, watery eyes, and blurred vision. These side-effects are mild and temporary. It may also cause inflammation of the cornea (clear outer layer of the eye), which is a serious side-effect and may cause vision problems. If any of these side-effects persist, consult your doctor immediately. Inform your doctor before using Gatipred if you have allergic reactions to medicines, tuberculosis, damaged cornea, ulcers in the eye, eye infection and producing pus, open lesions in the eye and glaucoma (a condition where the pressure inside the eye is increased). Pregnant and breastfeeding women should consult their doctor before starting Gatipred. This medicine may cause temporary blurred vision; hence drive only when you are alert and have clear vision.

Combinib 250mg Tablet is used in the treatment of breast cancer. It works by stopping or slowing down the growth of cancer cells. It is either used alone or in combination with some other medicine to cure advanced-stage breast cancer. Combinib 250mg Tablet should be taken on an empty stomach or an hour before or 2 hours after a meal. The dose and duration vary according to the severity of your condition and your response to treatment. Take it exactly as prescribed to avoid serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include nausea, headache, back pain, and breathing difficulty. It may cause severe diarrhea, drink plenty of fluids or consult with your doctor if it bothers you. You may be asked for regular monitoring of blood pressure while taking this medicine. Inform your doctor if you notice a severe headache, confusion, problems with your eyesight, nausea, or vomiting. Your doctor may check your liver function before, during, and after treatment with this medicine. Before taking Combinib 250mg Tablet, let your doctor know if you have liver or kidney problems. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are taking. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details. Uses of Combinib Tablet Pancreatic cancer Small cell lung cancer Liver cancer Kidney cancer Thyroid cancer Blood cancer (Chronic myeloid leukaemia) Gastrointestinal stromal tumour Cancer of colon and rectum Non-small cell lung cancer Soft tissue sarcoma Chronic idiopathic myelofibrosis Breast cancer Side effects of Combinib Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Combinib Abdominal pain Back pain Breathing problems Constipation Cough Diarrhea Fatigue Headache Hot flashes Increased bilirubin in the blood Insomnia (difficulty in sleeping) Joint pain Liver damage Loss of appetite Mucosal inflammation Nausea Pain in extremities Rash Stomatitis (Inflammation of the mouth) Vomiting Weakness Weight gain How to use Combinib Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Combinib 250mg Tablet is to be taken empty stomach. How Combinib Tablet works Combinib 250mg Tablet is an anti-cancer medication. It works against the HER2 (human epidermal growth factor receptor protein) receptors and EGFRs (epidermal growth factor receptor) which are responsible for the over-proliferation of cells. This is how it inhibits the growth of cancerous cells causing downstream signaling pathways. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Combinib 250mg Tablet. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Combinib 250mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding UNSAFE Combinib 250mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. warnings Driving UNSAFE Combinib 250mg Tablet may cause side effects which could affect your ability to drive. warnings Kidney CAUTION Combinib 250mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Combinib 250mg Tablet may be needed. Please consult your doctor. Limited information is available on the use of Combinib 250mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease. warnings Liver CAUTION Combinib 250mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Combinib 250mg Tablet may be needed. Please consult your doctor. Limited information is available on the use of this medicine in patients with the severe liver disease.

Marketer Getwell Pharma (I) Pvt Ltd SALT COMPOSITION Thiotepa (15mg) Storage Store below 30°C Uses of Tepawel Injection Malignant melanoma Hodgkin’s disease Multiple myeloma Brain tumor Blood cancer Breast cancer Non-small cell lung cancer Ovarian cancer Lung cancer Product introduction Tepawel 15mg Injection is used in the treatment of cancers of the brain, breast, lungs, and ovaries. It is used in combination with other cancer medicine during hematopoietic progenitor cell transplantation (HPCT). It may be also used to treat other conditions, as determined by the doctor. Tepawel 15mg Injection is generally given under the supervision of a healthcare professional. Your doctor will decide the dose and duration of the treatment based on the severity of your condition and what you are being treated for. It may take several weeks or months for you to see or feel the benefits but do not stop getting the injection unless your doctor tells you to. The most common side effects of this medicine include decreased white blood count, anemia, low blood platelets, increased liver enzymes, increased bilirubin in the blood, mucosal inflammation, hemorrhage, diarrhea, blood in urine, and rash. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidneys, liver, and heart function during treatment with this medicine. Before taking it, tell your doctor if you have bleeding, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. Side effects of Tepawel Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Tepawel Decreased white blood cell count (neutrophils) Anemia (low number of red blood cells) Low blood platelets Increased liver enzymes Increased bilirubin in the blood Mucosal inflammation Hemorrhage Rash Diarrhea Blood in urine How to use Tepawel Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Tepawel Injection works Tepawel 15mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Tepawel 15mg Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Tepawel 15mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding UNSAFE Tepawel 15mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. warnings Driving UNSAFE Tepawel 15mg Injection may cause side effects which could affect your ability to drive. It is likely that certain adverse events of Tepawel 15mg Injection are dizziness, headache, and blurred vision which could affect your ability to drive. warnings Kidney SAFE IF PRESCRIBED Tepawel 15mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Tepawel 15mg Injection may not be needed in these patients. Please consult your doctor. warnings Liver CAUTION Tepawel 15mg Injection should be used with caution in patients with liver disease. Dose adjustment of Tepawel 15mg Injection may be needed. Please consult your doctor. Regular monitoring of liver function tests may be advised while you are taking this medicine.

Marketer Getwell Pharma (I) Pvt Ltd SALT COMPOSITION Irinotecan (100mg) Storage Store below 25°C Uses of Rinowel Injection Ovarian cancer Small cell lung cancer Cervical cancer Cancer of colon and rectum Uses of Rinowel Injection Ovarian cancer Small cell lung cancer Cervical cancer Cancer of colon and rectum Side effects of Rinowel Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Rinowel Fatigue Nausea Vomiting Weakness Hair loss Fever Anemia (low number of red blood cells) Diarrhea Decreased white blood cell count (neutrophils) Decreased appetite Mucosal inflammation How to use Rinowel Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Rinowel Injection works Rinowel 100mg Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase I) involved in DNA multiplication of the cancer cells. This slows the growth of cancer cells and eventually kills them. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Rinowel 100mg Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Rinowel 100mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding UNSAFE Rinowel 100mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. warnings Driving UNSAFE Rinowel 100mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. warnings Kidney SAFE IF PRESCRIBED Rinowel 100mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Rinowel 100mg Injection may not be needed in these patients. Please consult your doctor. Use of this medicine is not recommended for patients on dialysis. warnings Liver CONSULT YOUR DOCTOR There is limited information available on the use of Rinowel 100mg Injection in patients with liver disease. Please consult your doctor.

Regonat Tablet is a Tyrosine kinase inhibitors used in the treatment of cancer of colon and rectum. Regonat Tablet should be taken with food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include infection, low blood platelets, anemia, decreased appetite, hemorrhage, and high blood pressure. It can also cause voice change, diarrhea, stomatitis, vomiting, nausea, bilirubin in urine, increased liver enzyme, rash, weakness, pain, fever, mucosal inflammation, and weight loss. If any of these side effects bother you, let your doctor know. Regular blood tests are required to check your blood cells along with liver functioning.

Marketer Fresenius Kabi India Pvt Ltd SALT COMPOSITION Irinotecan (100mg) Storage Store below 25°C Uses of Irinotel Injection Ovarian cancer Small cell lung cancer Cervical cancer Cancer of colon and rectum Product introduction Irinotel 100mg Injection is used in the treatment of cancer of colon and rectum. It shows its working by stopping or slowing down the growth of cancer cells. Irinotel 100mg Injection is given as an IV infusion into vein by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include fatigue, nausea, vomiting, weakness, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Inform your doctor if you notice fever, sore throat, and continuous episodes of diarrhea. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels. Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. Side effects of Irinotel Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Irinotel Fatigue Nausea Vomiting Weakness Hair loss Fever Anemia (low number of red blood cells) Diarrhea Decreased white blood cell count (neutrophils) Decreased appetite Mucosal inflammation How to use Irinotel Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Irinotel Injection works Irinotel 100mg Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase I) involved in DNA multiplication of the cancer cells. This slows the growth of cancer cells and eventually kills them. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Irinotel 100mg Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Irinotel 100mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. warnings Breast feeding UNSAFE Irinotel 100mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. warnings Driving UNSAFE Irinotel 100mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Marketer Khandelwal Laboratories Pvt Ltd SALT COMPOSITION Irinotecan (40mg) Storage Store below 30°C Uses of Irinot Injection Ovarian cancer Small cell lung cancer Cervical cancer Cancer of colon and rectum Product introduction Irinot 40mg Injection is used in the treatment of cancer of colon and rectum. It shows its working by stopping or slowing down the growth of cancer cells. Irinot 40mg Injection is given as an IV infusion into vein by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include fatigue, nausea, vomiting, weakness, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Inform your doctor if you notice fever, sore throat, and continuous episodes of diarrhea. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels. Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. Side effects of Irinot Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Irinot Fatigue Nausea Vomiting Weakness Hair loss Fever Anemia (low number of red blood cells) Diarrhea Decreased white blood cell count (neutrophils) Decreased appetite Mucosal inflammation How to use Irinot Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Irinot Injection works Irinot 40mg Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase I) involved in DNA multiplication of the cancer cells. This slows the growth of cancer cells and eventually kills them.