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General Medicine

Nor-ADR Injection is a brand of Noradrenaline (Norepinephrine) Bitartrate Injection, manufactured by American Remedies. It is primarily used in critical care settings to manage severe hypotension (low blood pressure) and shock. ________________________________________ ✅ Primary Uses Nor-ADR Injection is indicated for: • Septic Shock: A life-threatening condition caused by severe infection leading to dangerously low blood pressure. • Cardiogenic Shock: A state where the heart is unable to pump sufficient blood to meet the body's needs. Anaphylactic Shock: A severe allergic reaction causing a sudden drop in blood pressure. • Hypotension During Surgery or Trauma: To maintain adequate blood pressure during and after surgical procedures or traumatic events. • Cardiac Arrest: As an adjunct in the management of cardiac arrest to improve blood flow to vital organs. These indications are supported by clinical guidelines and pharmacological references. ________________________________________ ⚙️ Mechanism of Action Noradrenaline is a potent vasopressor that works by: Alpha-1 Adrenergic Receptor Activation: Causing vasoconstriction, which increases systemic vascular resistance and raises blood pressure. • Beta-1 Adrenergic Receptor Activation: Increasing heart rate and myocardial contractility, thereby enhancing cardiac output. This dual action helps restore blood pressure and improve perfusion to vital organs in shock states. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Administration: Should be administered intravenously under strict medical supervision, typically in an intensive care unit (ICU) setting. • Monitoring: Continuous monitoring of blood pressure and heart rate is essential during administration. • Contraindications: Should not be used in patients with mesenteric or peripheral vascular thrombosis unless absolutely necessary. Common Side Effects: • Hypertension (high blood pressure) • Headache Nausea • Anxiety • Dizziness Serious Side Effects: • Arrhythmias (irregular heartbeats) • Tissue necrosis at the injection site • Reduced renal perfusion leading to renal failure Immediate medical attention is required if any serious side effects occur.

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General Medicine

Nezolid 600 Injection is a brand of Linezolid Injection 600 mg/300 mL, manufactured by American Remedies. Linezolid is an antibiotic belonging to the oxazolidinone class, effective against various serious bacterial infections. ________________________________________ ✅ Primary Uses Nezolid 600 Injection is indicated for the treatment of: • Nosocomial Pneumonia: Hospital-acquired pneumonia caused by susceptible strains of bacteria. • Community-Acquired Pneumonia (CAP): Pneumonia acquired outside of healthcare settings. • Complicated Skin and Skin Structure Infections (cSSSIs): Infections involving deeper layers of the skin and underlying tissues. • Vancomycin-Resistant Enterococcus faecium (VRE) Infections: Including cases with concurrent bacteremia. These infections are typically caused by Gram-positive bacteria, including multidrug-resistant strains. ________________________________________ ⚙️ Mechanism of Action Linezolid works by inhibiting bacterial protein synthesis. It binds to the bacterial ribosome, preventing the formation of the initiation complex necessary for protein production, thereby halting bacterial growth. This bacteriostatic action is particularly effective against Gram-positive organisms. ________________________________________ ⚠️ Precautions • Drug Interactions: Avoid concurrent use with monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants (TCAs), and certain other medications due to the risk of serotonin syndrome. • Pre-existing Conditions: Use with caution in patients with a history of seizures, diabetes mellitus, liver cirrhosis, or renal impairment. • Dietary Restrictions: Limit intake of foods high in tyramine (e.g., aged cheeses, cured meats, soy products) to reduce the risk of hypertensive reactions. • Pregnancy and Lactation: Consult a healthcare provider before use during pregnancy or breastfeeding.

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General Medicine

Nitrocan 25 Injection is a brand of Nitroglycerin Injection 25 mg/5 mL, manufactured by American Remedies. It is primarily used in hospital settings for the management of certain cardiovascular conditions. ________________________________________ ✅ Primary Uses Nitrocan 25 Injection is indicated for: • Angina Pectoris: To treat and prevent chest pain caused by reduced blood flow to the heart. • Acute Myocardial Infarction (Heart Attack): To alleviate chest pain and improve blood flow to the heart muscle. Hypertension During Surgery: To control high blood pressure during and after surgical procedures. • Congestive Heart Failure: To reduce the workload on the heart and improve symptoms. ________________________________________ ⚙️ Mechanism of Action Nitroglycerin is a nitrate that, once administered, is converted into nitric oxide in the body. This leads to the relaxation and dilation of blood vessels, improving blood flow and reducing the heart's workload. ________________________________________ ⚠️ Precautions • Contraindications: Should not be used in patients with severe anemia, hypotension, or those taking medications for erectile dysfunction (e.g., sildenafil, tadalafil) due to the risk of a significant drop in blood pressure. • Monitoring: Requires careful monitoring of blood pressure and heart rate during administration. • Administration: Administered intravenously under medical supervision; dosage and duration are determined by the healthcare provider. ________________________________________ 💊 Common Side Effects • Headache • Dizziness or lightheadedness • Hypotension (low blood pressure) • Nausea or vomiting • Flushing

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General Medicine

Milrican 10 is a brand of Milrinone Lactate Injection, manufactured by American Remedies. Milrinone is a phosphodiesterase-3 (PDE3) inhibitor that serves as both an inotropic agent and a vasodilator. ________________________________________ ✅ Primary Uses of Milrican 10 Milrican 10 is indicated for the short-term intravenous treatment of: • Severe congestive heart failure: Particularly in patients unresponsive to conventional therapies. • Acute decompensated heart failure: Including low output states following cardiac surgery. It is commonly used in intensive care units or during cardiac procedures to support heart function. ________________________________________ ⚙️ Mechanism of Action Milrinone works by inhibiting PDE3, leading to increased cyclic AMP (cAMP) levels in cardiac and vascular smooth muscle cells. This results in: • Increased myocardial contractility: Enhancing the heart's ability to pump blood. • Vasodilation: Relaxing blood vessels, which reduces the heart's workload and improves blood flow. ________________________________________ ⚠️ Important Considerations • Administration: Milrican 10 should only be administered intravenously under the supervision of a healthcare professional. • Monitoring: Patients receiving Milrican 10 require close monitoring of blood pressure, heart rate, and kidney function. • Contraindications: Not recommended for patients with severe dehydration, electrolyte imbalances, or known hypersensitivity to milrinone. • Pregnancy and Breastfeeding: Consult a doctor before use if pregnant or breastfeeding.

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General Medicine

Menacan K3 Injection is a brand name for Menadione Sodium Bisulphite Injection, which is a synthetic form of Vitamin K3. It is primarily used in medical and veterinary settings to address Vitamin K deficiencies and related conditions. ________________________________________ 💉 Medical Uses Menacan K3 Injection is indicated for: • Treatment of Vitamin K Deficiency: Essential for synthesizing clotting factors II, VII, IX, and X in the liver. A deficiency can lead to bleeding disorders. • Management of Hypoprothrombinemia: A condition characterized by low levels of prothrombin, increasing the risk of bleeding • Reversal of Anticoagulant Effects: Used in cases of anticoagulant overdose, particularly when rapid reversal is necessary. • Support in Liver Disease: Beneficial for patients with liver disease where vitamin K absorption is impaired. • Treatment of Malabsorption Syndromes: In patients with conditions that disrupt vitamin K absorption. ________________________________________ ⚠️ Important Considerations • Administration: Should only be administered by a trained healthcare professional. Self-administration is not recommended. • Contraindications: Not suitable for individuals with G6PD deficiency, as it can cause serious side effects. Also, use with caution in patients with liver or kidney disease, or those who are pregnant or breastfeeding. • Side Effects: May include facial flushing, sweating, injection site reactions, hemolysis, and altered taste. These side effects are generally mild and resolve over time.

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General Medicine

Kdion 1mg Injection 0.5 ml is a medicine used to treat vitamin K deficiency in the body. It helps in improving conditions caused due to low levels of vitamin K in the body. Vitamin K is an important nutrient that is necessary for blood clotting and bone metabolism. Kdion 1mg Injection 0.5 ml is given under the supervision of a doctor to a nurse and should not be self-administered. You should take it regularly to get the most benefit from it. This medicine may be only part of a complete program of treatment that also includes making changes to your diet and taking vitamin supplements. Kdion 1mg Injection 0.5 ml is generally safe with little or no side effects. However, it may cause pain, redness, or swelling at the site of injection in some people. Let your doctor know if they persist or get worse.

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Heart Disorder

Kenadion 1mg Injection 0.5 ml is a medicine used to treat vitamin K deficiency in the body. It helps in improving conditions caused due to low levels of vitamin K in the body. Vitamin K is an important nutrient that is necessary for blood clotting and bone metabolism. Kenadion 1mg Injection 0.5 ml is given under the supervision of a doctor to a nurse and should not be self-administered. You should take it regularly to get the most benefit from it. This medicine may be only part of a complete program of treatment that also includes making changes to your diet and taking vitamin supplements. Kenadion 1mg Injection 0.5 ml is generally safe with little or no side effects. However, it may cause pain, redness, or swelling at the site of injection in some people. Let your doctor know if they persist or get worse.

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Kidney Disease Medicine

Encicarb 100mg Injection is an iron replacement product. It is used to treat a type of anemia in which the number of red blood cells is less due to a low level of iron in your body (iron-deficiency anemia). Iron is needed to produce the red blood cells that carry oxygen around your body. Encicarb 100mg Injection is generally given by a doctor or nurse. You should not self-administer this medicine at home. You will be watched carefully to make sure you do not have an allergic reaction. Your doctor will decide how many doses you need depending on the cause of your anemia. It is advisable to eat iron-rich foods like meat, eggs, raisins, broccoli and lentils along with taking Encicarb 100mg Injection. The most common side effects include vomiting, nausea, constipation, and dark-colored stools. Most of these usually go away within a short time. If you are bothered by them or they go on for longer, talk to your doctor or nurse.

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Anti Cancer Medicine

Samenza 40mg Capsule is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone. Samenza 40mg Capsule should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Headache, hot flashes, weakness and high blood pressure is very common side effect of this medicine. Other than this, fractures, falls, dry skin, pruritus,decreased appetite, and constipation might be observed as side effects. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out.

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