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Pipracan 4.5 Injection is a combination antibiotic medication containing Piperacillin (4 g) and Tazobactam (0.5 g). This formulation is used to treat a wide range of serious bacterial infections that may not respond to other antibiotics. ________________________________________ 🔹 Common Uses Pipracan 4.5 Injection is prescribed for: • Hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) • Urinary tract infections (UTIs) • Intra-abdominal infections (e.g., peritonitis) • Skin and soft tissue infections, including diabetic foot infections • Gynecological infections, such as uterine infections • Bone and joint infections • Bloodstream infections (bacteremia) It is also used for prophylactic treatment in surgical procedures to prevent infections. ________________________________________ 🔹 How It Works • Piperacillin is a broad-spectrum penicillin antibiotic that inhibits bacterial cell wall synthesis, leading to bacterial cell death. • Tazobactam is a beta-lactamase inhibitor that protects piperacillin from degradation by beta-lactamase enzymes produced by certain bacteria, thereby enhancing its efficacy. This combination allows Pipracan 4.5 to target a wide array of bacteria, including those resistant to other antibiotics. ________________________________________ 🔹 Administration Pipracan 4.5 Injection is administered intravenously by a healthcare professional. The dosage and duration of treatment depend on the type and severity of the infection, as well as the patient's medical condition. Self-administration is not recommended. ________________________________________ 🔹 Side Effects Common side effects may include: • Nausea or vomiting • Diarrhea • Rash or itching • Pain, redness, or swelling at the injection site Serious side effects are rare but can include allergic reactions, liver enzyme abnormalities, or blood disorders. Seek immediate medical attention if you experience symptoms like difficulty breathing, swelling of the face or throat, or unusual bruising or bleeding. ________________________________________ 🔹 Precautions Before using Pipracan 4.5 Injection, inform your doctor if you have: Allergies to penicillins or beta-lactam antibiotics • Kidney or liver disease • A history of gastrointestinal diseases, such as colitis • Bleeding disorders • Undergoing dialysisUse during pregnancy and breastfeeding should be discussed with your healthcare provider. The medication should only be used if the potential benefits justify the potential risks.

Nor-ADR Injection is a brand of Noradrenaline (Norepinephrine) Bitartrate Injection, manufactured by American Remedies. It is primarily used in critical care settings to manage severe hypotension (low blood pressure) and shock. ________________________________________ ✅ Primary Uses Nor-ADR Injection is indicated for: • Septic Shock: A life-threatening condition caused by severe infection leading to dangerously low blood pressure. • Cardiogenic Shock: A state where the heart is unable to pump sufficient blood to meet the body's needs. Anaphylactic Shock: A severe allergic reaction causing a sudden drop in blood pressure. • Hypotension During Surgery or Trauma: To maintain adequate blood pressure during and after surgical procedures or traumatic events. • Cardiac Arrest: As an adjunct in the management of cardiac arrest to improve blood flow to vital organs. These indications are supported by clinical guidelines and pharmacological references. ________________________________________ ⚙️ Mechanism of Action Noradrenaline is a potent vasopressor that works by: Alpha-1 Adrenergic Receptor Activation: Causing vasoconstriction, which increases systemic vascular resistance and raises blood pressure. • Beta-1 Adrenergic Receptor Activation: Increasing heart rate and myocardial contractility, thereby enhancing cardiac output. This dual action helps restore blood pressure and improve perfusion to vital organs in shock states. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Administration: Should be administered intravenously under strict medical supervision, typically in an intensive care unit (ICU) setting. • Monitoring: Continuous monitoring of blood pressure and heart rate is essential during administration. • Contraindications: Should not be used in patients with mesenteric or peripheral vascular thrombosis unless absolutely necessary. Common Side Effects: • Hypertension (high blood pressure) • Headache Nausea • Anxiety • Dizziness Serious Side Effects: • Arrhythmias (irregular heartbeats) • Tissue necrosis at the injection site • Reduced renal perfusion leading to renal failure Immediate medical attention is required if any serious side effects occur.

MNOphyllin Injection is a brand of Aminophylline Injection, manufactured by American Remedies. Aminophylline is a bronchodilator that works by relaxing the muscles of the air passages in the lungs, making it easier to breathe. ________________________________________ ✅ Primary Uses MNOphyllin Injection is primarily used for: • Asthma: A chronic condition where the airways become inflamed and narrow, leading to difficulty in breathing. • Chronic Obstructive Pulmonary Disease (COPD): A group of lung diseases that block airflow and make breathing difficult. • Bronchospasm: A condition where the muscles around the airways tighten, leading to wheezing and shortness of breath. It is administered intravenously in a hospital setting under medical supervision. ________________________________________ ⚙️ Mechanism of Action Aminophylline works by: • Relaxing the bronchial muscles: This leads to the widening of the air passages, making it easier to breathe. • Increasing the strength of the diaphragm: This enhances the ability to breathe effectively. • Reducing airway responsiveness to irritants: This helps in decreasing inflammation and bronchoconstriction. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Medical History: Inform your doctor if you have a history of heart disease, liver or kidney disorders, or seizures. • Pregnancy and Breastfeeding: Consult your doctor before use if pregnant or breastfeeding. • Drug Interactions: Certain medications can interact with Aminophylline, so it's essential to inform your healthcare provider about all medicines you are taking. Common Side Effects: • Nausea • Vomiting • Headache • Restlessness • Dizziness Serious Side Effects: • Irregular heartbeats • Seizures • Severe allergic reactions If you experience any of these serious side effects, seek immediate medical attention.

DARCEPT 40MG INJECTION belongs to the class of medication called 'blood-forming agent' primarily used to treat anaemia (low red blood cell count) in person with long-term serious (chronic) kidney disease and persons receiving chemotherapy for some types of cancer (except for bone marrow or blood cells' cancer). DARCEPT 40MG INJECTION helps to reverse anaemia and reduce the need for blood transfusion. Anaemia occurs when the body has a lower amount of red blood cells or haemoglobin. In chronic kidney disease, the kidney gets damaged and doesn't filter the blood, leading to anaemia. DARCEPT 40MG INJECTION contains a protein 'Darbepoetin alfa' which works by providing signals to the bone marrow to make more red blood cells. DARCEPT 40MG INJECTION is a biologic response modifier and erythropoiesis-stimulating protein. In chronic kidney disease, when the kidney fails to produce sufficient 'erythropoietin protein' which aids in the formation of red blood cells, DARCEPT 40MG INJECTION stimulates the production of this protein in the bone marrow. DARCEPT 40MG INJECTION will be injected by the healthcare provider. Do not self-administer. The most common side effects of DARCEPT 40MG INJECTION are shortness of breath, cough, low blood pressure during dialysis, headache, body aches, diarrhoea, injection site pain and abdominal pain. Most of these sides effects of DARCEPT 40MG INJECTION do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Alpostin 500mcg Injection Salt: Alprostadil (500mcg) Description Alpostin 500mcg Injection is used to treat patent ductus arteriosus (PDA), a heart defect that occurs in newborns. It improves blood circulation in such babies and helps treat this defect. Alpostin 500mcg Injection is used to treat patent ductus arteriosus (PDA), a heart defect that occurs in newborns. It improves blood circulation in such babies and helps treat this defect. Alpostin 500mcg Injection is given as an injection by a doctor or nurse and should not be used without medical supervision. The most common side effects of this medicine are interrupted breathing (apnea) and a high temperature for a short time period (transient pyrexia/fever). If your baby has these or any other side effects, let your doctor know. All babies can have Alpostin 500mcg Injection if they need it. The doctor will carry out tests before deciding whether to give this medicine to your baby. However, if your baby develops any signs of allergy to this medicine, such as wheezing, breathlessness, swelling of the face, hands, itchy rash, or redness of the skin, it is advised to not use this medicine. Consult your doctor if you have any doubts. Benefits 1. In Treatment of Patent ductus arteriosus (PDA): Patent ductus arteriosus (PDA) is a persistent opening between the two major blood vessels leading from the heart. Usually this opening closes shortly after birth, but it can remain open and lead to this heart defect in babies. Alpostin 500mcg Injection improves blood flow in such babies who have PDA. It is given as an injection by a doctor or nurse in a hospital setup. Follow your doctor’s instructions carefully to get the most benefit. Side Effects Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Common side effects of Alpostin: - Apnea (absence of breathing) - Fever

Zynesp 200 mcg Injection belongs to the class of medication called 'blood-forming agent' primarily used to treat anaemia (low red blood cell count) in person with long-term serious (chronic) kidney disease and persons receiving chemotherapy for some types of cancer (except for bone marrow or blood cells' cancer). Zynesp 200 mcg Injection helps to reverse anaemia and reduce the need for blood transfusion. Anaemia occurs when the body has a lower amount of red blood cells or haemoglobin. In chronic kidney disease, the kidney gets damaged and doesn't filter the blood, leading to anaemia. Zynesp 200 mcg Injection contains a protein 'Darbepoetin alfa' which works by providing signals to the bone marrow to make more red blood cells. Zynesp 200 mcg Injection is a biologic response modifier and erythropoiesis-stimulating protein. In chronic kidney disease, when the kidney fails to produce sufficient 'erythropoietin protein' which aids in the formation of red blood cells, Zynesp 200 mcg Injection stimulates the production of this protein in the bone marrow. Zynesp 200 mcg Injection will be injected by the healthcare provider. Do not self-administer. The most common side effects of Zynesp 200 mcg Injection are shortness of breath, cough, low blood pressure during dialysis, headache, body aches, diarrhoea, injection site pain and abdominal pain. Most of these sides effects of Zynesp 200 mcg Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. If you have uncontrolled/untreated high blood pressure or red cell aplasia (a type of anaemia) due to darbepoetin alfa or epoetin alfa, please inform your doctor before taking Zynesp 200 mcg Injection to avoid any complications. Also, mention all the other medications you are taking to affect the way Zynesp 200 mcg Injection works. Inform your doctor immediately, if you feel weak, lightheaded, tired, or short of breath, or if your skin looks pale as it may be signs that the body has stopped responding to Zynesp 200 mcg Injection .

Introduction to Lastet 100mg Injection Lastet 100mg injection is an anticancer drug with the ingredient Etoposide. It belongs to the medication class known as cytostatic. It is used to treat certain types of cancers such as testicular cancer, small-cell lung cancer, acute myeloid leukemia (blood cancer), tumor in the lymphatic system (Hodgkin’s lymphoma, non-Hodgkin’s lymphoma), and ovarian cancer in adults. Talk to your doctor if you had or currently having radiotherapy or chemotherapy. Report to your doctor if you have any infections or low levels of protein (albumin) in your blood. Lastet 100mg Injection should not be taken if you have recently been vaccinated with yellow fever or any live vaccines. Before starting treatment with this medicine, it is very important to tell your physician if you currently or previously had any medical conditions of kidney problems or liver disorders. Both women and men should use effective birth control during the treatment and at least 6 months after the last dose. In men, it is recommended not to father a child during and up to 6 months after the treatment. So it is advised to get suggestions about fertility concerns from your doctor. Administration of Lastet 100mg injection may cause a reduction in the level of blood cells and increase the risk of developing infections. So, your doctor may perform blood tests regularly to monitor your kidney and liver function. It is unknown whether it is safe to use on a child. Uses of Lastet 100mg Injection Testicular cancer Small-cell lung cancer Acute myeloid leukemia (blood cancer) Hodgkin’s lymphoma and non-Hodgkin’s lymphoma Ovarian cancer Therapeutic Effects of Lastet 100mg Injection Lastet 100mg works by inhibiting the activity of topoisomerase II (essential for cell replication) and DNA synthesis, which will prevent cancer cells from growing and multiplying, ultimately leading to cell death. Interaction of Lastet 100mg Injection with other drugs Inform your healthcare provider about all your medicines, including prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products. Certain medications such as Ciclosporin, Phenytoin, Phenobarbitone, Warfarin, Anthracyclines, Aspirin, and Fosphenytoin may interact with Lastet 100mg and reduce effectiveness by causing undesirable side effects. More Information about Lastet 100mg Injection Keep Lastet 100mg out of sight and reach of children. Store at a controlled room temperature between 15°C to 30°C. Store in the original package Do not refrigerate or freeze. How to consume Lastet 100mg Injection Lastet 100mg injection is administered as an intravenous infusion into the vein. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administrate. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person. Safety Advices for Lastet 100mg Injection Image Not Available Pregnancy Do not take this Lastet 100mg if you are pregnant because it may cause harm to the unborn baby. Consult your doctor before starting the treatment. Image Not Available Breast Feeding It is unsafe to breastfeed while taking Lastet 100mg because it can cause toxicity to the baby. Please consult your physician for more advice. Image Not Available Lungs Consult your doctor if you experience any lung-related symptoms like; shortness of breath or lung inflammation while taking a Lastet 100mg injection. Image Not Available Liver You need to tell your doctor if you have any liver disorders before taking Lastet 100mg Injection. Your doctor may perform blood tests regularly to monitor your condition. Consult your doctor for more information. Image Not Available Alcohol It is unknown if drinking alcohol while taking a Lastet 100mg injection is safe. Please speak with your physician. Image Not Available Driving Driving while taking a Lastet 100mg injection is unsafe because this medicine can cause tiredness, lightheadedness, or dizziness. Side Effects of Lastet 100mg Injection Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious Severe allergic reactions (swelling of tongue, or throat, breathing difficulties, rash, flushing, fast heartbeat) Irregular heartbeat (arrhythmia) Blood disorder Hepatotoxicity (damage to the liver) Acute leukemia Common Nausea, vomiting Loss of appetite Abdominal pain Constipation, diarrhea Changes in skin color Weakness Asthenia (feeling weak) Temporary hair loss High or low blood pressure Dizziness Redness of the skin Sore lips, throat, or mouth ulcers Word of Advice Discuss your fertility problem with the doctor since, in men, it is advised not to father a child during and after the 6 months of treatment. So it is advised to get suggestions about fertility concerns. Avoid planning for the pregnancy.

Dopacan Injection is a brand of Dopamine Hydrochloride, a potent vasopressor and inotropic agent used in critical care settings to manage various cardiovascular conditions. It is administered intravenously under medical supervision. ________________________________________ 🩺 Medical Uses Dopacan Injection is indicated for: • Shock Management: Including septic shock, cardiogenic shock, and hypovolemic shock. • Acute Heart Failure: To improve cardiac output and perfusion. • Severe Hypotension: Especially in patients unresponsive to volume resuscitation. • Renal Protection: To enhance renal blood flow and urine output in certain critically ill patients. Dopamine works by stimulating dopaminergic and beta-adrenergic receptors, leading to increased heart rate, contractility, and renal perfusion. At higher doses, it also stimulates alpha-adrenergic receptors, causing vasoconstriction and increased blood pressure. ________________________________________ ⚙️ Dosage and Administration Dopacan Injection is administered intravenously, with the dosage tailored to the patient's condition and response: • Low Dose (1–5 mcg/kg/min): Primarily stimulates dopaminergic receptors, increasing renal blood flow and urine output. • Medium Dose (5–15 mcg/kg/min): Stimulates beta-1 adrenergic receptors, enhancing heart rate and contractility. • High Dose (15–50 mcg/kg/min): Stimulates alpha-1 adrenergic receptors, leading to vasoconstriction and increased blood pressure. Continuous monitoring of blood pressure, heart rate, and urine output is essential during administration. ________________________________________ ⚠️ Precautions and Contraindications Before using Dopacan Injection, inform your healthcare provider if you have: • Allergies to dopamine or other components of the injection. • A history of heart rhythm disorders or coronary artery disease. • Pheochromocytoma (a rare tumor of the adrenal glands). • Diabetes, asthma, or sulfite allergies. • Circulatory disorders such as Raynaud's disease or Buerger's disease. • Recent use of monoamine oxidase inhibitors (MAOIs). This medication is typically administered by healthcare professionals in a clinical setting and is not intended for self-administration. ________________________________________ 💊 Side Effects Common side effects may include: • Palpitations or increased heart rate. • Nausea and vomiting. • Headache. • Difficulty breathing. • Gangrene (in rare cases, due to excessive vasoconstriction). Serious side effects are rare but can occur. Seek immediate medical attention if you experience symptoms like chest pain, shortness of breath, or signs of gastrointestinal bleeding.

Dobutacan 12 Injection is a brand of Dobutamine Hydrochloride 12.5 mg/mL, a synthetic catecholamine used in critical care settings to support heart function. It is administered intravenously under medical supervision. ________________________________________ 🩺 Medical Uses Dobutacan 12 Injection is indicated for: • Cardiac Decompensation: Acute heart failure due to conditions like myocardial infarction, cardiomyopathies, or post-cardiac surgery. • Cardiogenic Shock: A state of low cardiac output leading to inadequate tissue perfusion. • Septic Shock: A severe infection causing low blood pressure and organ dysfunction. • Stress Echocardiography: As a pharmacological agent to assess coronary artery disease when exercise is not feasible. It works by stimulating beta-1 adrenergic receptors, increasing heart contractility and stroke volume, thereby improving cardiac output. ________________________________________ ⚙️ Dosage and Administration Dobutacan 12 Injection is administered intravenously in a hospital setting. The typical dosage ranges from 2.5 to 10 mcg/kg/min, adjusted based on the patient's response. In some cases, doses up to 20 mcg/kg/min may be required. ________________________________________ ⚠️ Precautions and Contraindications Before using Dobutacan 12 Injection, inform your healthcare provider if you have: • Allergies to dobutamine or other components of the injection. • A history of arrhythmias or heart disease. • Kidney or liver problems. • A history of stroke or blood clots. This medication is typically administered by healthcare professionals in a clinical setting and is not intended for self-administration. It is usually given as an intramuscular (IM) or intravenous (IV) injection. ________________________________________ 💊 Side Effects Common side effects may include: • Headache • Nausea or vomiting • Dizziness or lightheadedness • Injection site reactions (pain, redness, or swelling) Serious side effects are rare but can occur. Seek immediate medical attention if you experience symptoms like chest pain, shortness of breath, or signs of gastrointestinal bleeding.