Gufipol 5,00,000Unit Injection contains an active component as Polymyxin B. This medication is an antibiotic medication used to treat various bacterial infections, especially those caused by Gram-negative bacteria. It is commonly used when other antibiotics are ineffective or when dealing with multi-drug-resistant bacteria. It may be prescribed for conditions such as urinary tract infections, pneumonia, bacterial skin infections, and ventilator-associated pneumonia. A urinary tract infection (UTI) is a bacterial infection that affects the urinary system, primarily the bladder, urethra, or kidneys. Pneumonia is a respiratory condition characterized by inflammation of the lungs, usually caused by infection from bacteria, viruses, or fungi. Ventilator-associated pneumonia (VAP) is a type of lung infection that occurs in patients who are on mechanical ventilation in the hospital, typically caused by bacteria entering the lungs through the ventilator tube. Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Gufipol Anaphylactic reaction Fever Kidney damage Neurotoxicity Injection site reactions (pain, swelling, redness)

Poly B 500000IU Injection is an antibiotic that fights bacteria. It is used to treat severe bacterial infections of the body. It works by killing and stopping the growth of bacteria that cause these problems. It is commonly used to treat critically ill patients admitted to the hospital. Poly B 500000IU Injection is given under the supervision of a healthcare professional. You should get the injections at the same time each day to get the most benefit and you should keep on taking this medicine for as long as you are prescribed it, even if your symptoms quickly improve. If you stop taking it too early the infection may return or worsen. Some people may develop side effects like anaphylactic reaction, kidney damage, neurotoxicity, fever, or pain, redness, and swelling at the site of injection. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or will not go away. Before starting treatment with this medicine, you should tell your doctor if you are allergic to any antibiotic or have any liver or kidney problems. Pregnant women should consult their doctor before using it. Your doctor may get regular blood tests done to monitor kidney function.

Poly Mxb 500000IU Injection is an antibiotic that fights bacteria. It is used to treat severe bacterial infections of the body. It works by killing and stopping the growth of bacteria that cause these problems. It is commonly used to treat critically ill patients admitted to the hospital. Poly Mxb 500000IU Injection is given under the supervision of a healthcare professional. You should get the injections at the same time each day to get the most benefit and you should keep on taking this medicine for as long as you are prescribed it, even if your symptoms quickly improve. If you stop taking it too early the infection may return or worsen. Some people may develop side effects like anaphylactic reaction, kidney damage, neurotoxicity, fever, or pain, redness, and swelling at the site of injection. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or will not go away.

Colistican 2 Injection is a brand of Colistimethate Sodium for Injection, manufactured by American Remedies. It is a polymyxin-class antibiotic used to treat serious infections caused by multidrug-resistant Gram-negative bacteria. ________________________________________ 🩺 Uses of Colistican 2 Injection Colistican 2 Injection is primarily indicated for: • Ventilator-Associated Pneumonia (VAP): A lung infection acquired during mechanical ventilation. • Bacteremia (Bloodstream Infection): Infections caused by resistant bacteria entering the bloodstream. • Lower Respiratory Tract Infections: Including severe cases of pneumonia and bronchitis. • Urinary Tract Infections (UTIs): Caused by multidrug-resistant Gram-negative organisms. These infections are typically caused by pathogens such as Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae, which are resistant to multiple antibiotics. ________________________________________ 💊 Mechanism of Action Colistimethate sodium is a prodrug that, upon administration, is converted to colistin. Colistin binds to the bacterial cell membrane, disrupting its structure and leading to cell death. It is particularly effective against aerobic Gram-negative bacteria with hydrophobic outer membranes. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Renal Function: Use with caution in patients with kidney impairment. • Neurological Effects: Monitor for signs of neurotoxicity, including dizziness and muscle weakness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Injection site reactions • Renal toxicity • Neurological symptoms (e.g., confusion, dizziness) • Gastrointestinal disturbances (e.g., nausea, vomiting) • Muscle weakness

Colistican 1 Injection is a brand of Colistimethate Sodium for Injection manufactured by American Remedies. Colistimethate sodium is a polymyxin-class antibiotic, also known as polymyxin E, used to treat serious infections caused by multidrug-resistant Gram-negative bacteria. ________________________________________ 🩺 Uses of Colistican 1 Injection Colistican 1 Injection is primarily used for: • Multidrug-Resistant Infections: Especially those caused by Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae. • Ventilator-Associated Pneumonia (VAP): A lung infection acquired during mechanical ventilation. • Urinary Tract Infections (UTIs): Caused by resistant Gram-negative bacteria. • Bloodstream Infections (Sepsis): Resulting from resistant pathogens. • Intra-abdominal Infections: Such as peritonitis. • Cystic Fibrosis: For chronic pulmonary infections due to Pseudomonas aeruginosa in both adults and children. ________________________________________ 💊 Mechanism of Action Colistimethate sodium is a prodrug that, upon administration, is converted to colistin. Colistin binds to the bacterial cell membrane, disrupting its structure and leading to cell death. It is particularly effective against aerobic Gram-negative bacteria with hydrophobic outer membranes. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Renal Function: Use with caution in patients with kidney impairment. • Neurological Effects: Monitor for signs of neurotoxicity, including dizziness and muscle weakness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Injection site reactions • Renal toxicity • Neurological symptoms (e.g., confusion, dizziness) • Gastrointestinal disturbances (e.g., nausea, vomiting) • Muscle weakness