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Eye Care

Paripher Eye Drop contains Phenylephrine Hydrochloride 10% and is primarily used in ophthalmology for its mydriatic (pupil-dilating) effects. This formulation is typically employed in clinical settings and is available by prescription.** ________________________________________ 🔍 Uses 1. Pupil Dilation (Mydriasis): Paripher is utilized to dilate the pupil during eye examinations and surgical procedures, allowing for a clearer view of the retina and other internal structures. 2. Treatment of Eye Redness and Irritation: As a decongestant, it constricts blood vessels in the eye, reducing redness and irritation caused by allergies or other factors. 3. Management of Uveitis: Phenylephrine's vasoconstrictive properties aid in managing inflammation associated with uveitis by decreasing blood flow to the affected area. 4. Adjunct in Nasal Decongestion: Though primarily an eye drop, Paripher's active ingredient is also utilized in nasal decongestants to relieve symptoms of the common cold. ________________________________________ ⚠️ Usage Instructions • Application: Instill the prescribed number of drops into the lower conjunctival sac of the eye. • Contact Lenses: Remove soft contact lenses before application and wait at least 10–15 minutes before reinsertion. • Avoid Contamination: Do not touch the dropper tip to any surface, including the eye, to prevent contamination. • Multiple Medications: If using other eye medications, wait at least 10 minutes before applying them to avoid dilution. ________________________________________ ⚠️ Safety and Side Effects • Common Side Effects: Temporary eye discomfort, such as stinging or burning sensations. • Serious Side Effects: Although rare, systemic absorption may lead to increased blood pressure, headache, or dizziness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding.

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General Medicine

Nor-ADR Injection is a brand of Noradrenaline (Norepinephrine) Bitartrate Injection, manufactured by American Remedies. It is primarily used in critical care settings to manage severe hypotension (low blood pressure) and shock. ________________________________________ ✅ Primary Uses Nor-ADR Injection is indicated for: • Septic Shock: A life-threatening condition caused by severe infection leading to dangerously low blood pressure. • Cardiogenic Shock: A state where the heart is unable to pump sufficient blood to meet the body's needs. Anaphylactic Shock: A severe allergic reaction causing a sudden drop in blood pressure. • Hypotension During Surgery or Trauma: To maintain adequate blood pressure during and after surgical procedures or traumatic events. • Cardiac Arrest: As an adjunct in the management of cardiac arrest to improve blood flow to vital organs. These indications are supported by clinical guidelines and pharmacological references. ________________________________________ ⚙️ Mechanism of Action Noradrenaline is a potent vasopressor that works by: Alpha-1 Adrenergic Receptor Activation: Causing vasoconstriction, which increases systemic vascular resistance and raises blood pressure. • Beta-1 Adrenergic Receptor Activation: Increasing heart rate and myocardial contractility, thereby enhancing cardiac output. This dual action helps restore blood pressure and improve perfusion to vital organs in shock states. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Administration: Should be administered intravenously under strict medical supervision, typically in an intensive care unit (ICU) setting. • Monitoring: Continuous monitoring of blood pressure and heart rate is essential during administration. • Contraindications: Should not be used in patients with mesenteric or peripheral vascular thrombosis unless absolutely necessary. Common Side Effects: • Hypertension (high blood pressure) • Headache Nausea • Anxiety • Dizziness Serious Side Effects: • Arrhythmias (irregular heartbeats) • Tissue necrosis at the injection site • Reduced renal perfusion leading to renal failure Immediate medical attention is required if any serious side effects occur.

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General Medicine

Dopacan Injection is a brand of Dopamine Hydrochloride, a potent vasopressor and inotropic agent used in critical care settings to manage various cardiovascular conditions. It is administered intravenously under medical supervision. ________________________________________ 🩺 Medical Uses Dopacan Injection is indicated for: • Shock Management: Including septic shock, cardiogenic shock, and hypovolemic shock. • Acute Heart Failure: To improve cardiac output and perfusion. • Severe Hypotension: Especially in patients unresponsive to volume resuscitation. • Renal Protection: To enhance renal blood flow and urine output in certain critically ill patients. Dopamine works by stimulating dopaminergic and beta-adrenergic receptors, leading to increased heart rate, contractility, and renal perfusion. At higher doses, it also stimulates alpha-adrenergic receptors, causing vasoconstriction and increased blood pressure. ________________________________________ ⚙️ Dosage and Administration Dopacan Injection is administered intravenously, with the dosage tailored to the patient's condition and response: • Low Dose (1–5 mcg/kg/min): Primarily stimulates dopaminergic receptors, increasing renal blood flow and urine output. • Medium Dose (5–15 mcg/kg/min): Stimulates beta-1 adrenergic receptors, enhancing heart rate and contractility. • High Dose (15–50 mcg/kg/min): Stimulates alpha-1 adrenergic receptors, leading to vasoconstriction and increased blood pressure. Continuous monitoring of blood pressure, heart rate, and urine output is essential during administration. ________________________________________ ⚠️ Precautions and Contraindications Before using Dopacan Injection, inform your healthcare provider if you have: • Allergies to dopamine or other components of the injection. • A history of heart rhythm disorders or coronary artery disease. • Pheochromocytoma (a rare tumor of the adrenal glands). • Diabetes, asthma, or sulfite allergies. • Circulatory disorders such as Raynaud's disease or Buerger's disease. • Recent use of monoamine oxidase inhibitors (MAOIs). This medication is typically administered by healthcare professionals in a clinical setting and is not intended for self-administration. ________________________________________ 💊 Side Effects Common side effects may include: • Palpitations or increased heart rate. • Nausea and vomiting. • Headache. • Difficulty breathing. • Gangrene (in rare cases, due to excessive vasoconstriction). Serious side effects are rare but can occur. Seek immediate medical attention if you experience symptoms like chest pain, shortness of breath, or signs of gastrointestinal bleeding.

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General Medicine

Dobutacan 12 Injection is a brand of Dobutamine Hydrochloride 12.5 mg/mL, a synthetic catecholamine used in critical care settings to support heart function. It is administered intravenously under medical supervision. ________________________________________ 🩺 Medical Uses Dobutacan 12 Injection is indicated for: • Cardiac Decompensation: Acute heart failure due to conditions like myocardial infarction, cardiomyopathies, or post-cardiac surgery. • Cardiogenic Shock: A state of low cardiac output leading to inadequate tissue perfusion. • Septic Shock: A severe infection causing low blood pressure and organ dysfunction. • Stress Echocardiography: As a pharmacological agent to assess coronary artery disease when exercise is not feasible. It works by stimulating beta-1 adrenergic receptors, increasing heart contractility and stroke volume, thereby improving cardiac output. ________________________________________ ⚙️ Dosage and Administration Dobutacan 12 Injection is administered intravenously in a hospital setting. The typical dosage ranges from 2.5 to 10 mcg/kg/min, adjusted based on the patient's response. In some cases, doses up to 20 mcg/kg/min may be required. ________________________________________ ⚠️ Precautions and Contraindications Before using Dobutacan 12 Injection, inform your healthcare provider if you have: • Allergies to dobutamine or other components of the injection. • A history of arrhythmias or heart disease. • Kidney or liver problems. • A history of stroke or blood clots. This medication is typically administered by healthcare professionals in a clinical setting and is not intended for self-administration. It is usually given as an intramuscular (IM) or intravenous (IV) injection. ________________________________________ 💊 Side Effects Common side effects may include: • Headache • Nausea or vomiting • Dizziness or lightheadedness • Injection site reactions (pain, redness, or swelling) Serious side effects are rare but can occur. Seek immediate medical attention if you experience symptoms like chest pain, shortness of breath, or signs of gastrointestinal bleeding.

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General Medicine

Diclocan AQ Injection is a brand of Diclofenac Sodium 75 mg/ml, a nonsteroidal anti-inflammatory drug (NSAID) used to manage acute pain and inflammation. It is commonly prescribed in clinical settings for conditions where rapid pain relief is necessary. ________________________________________ 🩺 Medical Uses Diclocan AQ Injection is utilized for: • Acute Inflammatory Conditions: Such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. • Musculoskeletal Injuries: Including sprains, strains, and fractures. • Postoperative Pain: For pain management following surgical procedures. • Acute Gout Attacks: To alleviate pain and inflammation associated with gout. • Renal and Biliary Colic: For pain relief due to kidney stones or gallstones. The injection works by inhibiting the synthesis of prostaglandins, chemicals in the body responsible for inflammation and pain . ________________________________________ ⚠️ Precautions and Contraindications Before administering Diclocan AQ Injection, inform your healthcare provider if you have: • Allergies to diclofenac or other NSAIDs. • A history of gastrointestinal issues, such as ulcers or bleeding. • Heart, liver, or kidney problems. • High blood pressure or a history of stroke. • Pregnancy, especially in the third trimester, or breastfeeding. This medication is typically administered by a healthcare professional in a clinical setting and is not intended for self-administration. It is usually given as an intramuscular (IM) or intravenous (IV) injection. ________________________________________ 💊 Side Effects Common side effects may include: • Injection site reactions (pain, redness, or swelling). • Nausea or vomiting. • Dizziness or headache. • Gastrointestinal discomfort. Serious side effects are rare but can occur. Seek immediate medical attention if you experience symptoms like chest pain, shortness of breath, or signs of gastrointestinal bleeding. ________________________________________

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General Medicine

CPM Injection refers to Chlorpheniramine Maleate Injection, a first-generation antihistamine commonly used in clinical settings to manage allergic reactions and related conditions. It is available in various strengths, such as 4 mg, 10 mg, and 20 mg per vial, and is administered via intravenous (IV) or intramuscular (IM) injection. ________________________________________ 🩺 Medical Uses CPM Injection is employed to treat a range of allergic and hypersensitivity conditions, including: • Acute Allergic Reactions: Such as anaphylaxis, where rapid intervention is crucial. • Chronic Allergies: Including hay fever, allergic rhinitis, and conjunctivitis. • Skin Conditions: Like urticaria (hives), angioedema (swelling), and pruritus (itching). • Pre-Medication: Administered before blood transfusions or certain medications to prevent allergic reactions. • Motion Sickness: To alleviate symptoms associated with nausea and vomiting. • Common Cold Symptoms: Such as sneezing and runny nose. Its rapid onset makes it particularly valuable in emergency and hospital settings. ________________________________________ ⚙️ Mechanism of Action Chlorpheniramine Maleate works by blocking histamine receptors (H1 receptors) in the body. Histamine is a chemical involved in allergic responses; by inhibiting its action, CPM reduces symptoms like itching, swelling, and redness. ________________________________________ 💉 Administration and Dosage CPM Injection is administered by healthcare professionals: • Intravenous (IV) Injection: For rapid onset of action. • Intramuscular (IM) Injection: For sustained release and longer duration of effect. The dosage and frequency depend on the specific condition being treated, the patient's age, weight, and overall health status. It is crucial to follow the prescribing healthcare provider's instructions. ________________________________________ ⚠️ Precautions and Contraindications Before administering CPM Injection, inform the healthcare provider if the patient has: • Allergy: To chlorpheniramine or any other antihistamines. • Medical Conditions: Such as glaucoma, high blood pressure, or gastrointestinal issues. • Pregnancy or Breastfeeding: Discuss potential risks and benefits. CPM may cause drowsiness; therefore, activities requiring alertness, like driving, should be avoided during treatment. Alcohol consumption should also be limited, as it can exacerbate drowsiness. ________________________________________ ⚠️ Side Effects Common side effects may include: • Drowsiness or sedation. • Dizziness or lightheadedness. • Dry mouth. • Blurred vision. • Nausea or vomiting. If any side effects persist or worsen, consult a healthcare provider promptly.

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General Medicine

Methylene Blue Injection is a versatile medication with several clinical uses. It’s a synthetic dye that also functions as a medicinal agent, especially in emergency and critical care settings. ✅ Primary Medical Uses of Methylene Blue Injection Methemoglobinemia Treatment Main use: It rapidly treats methemoglobinemia, a condition where hemoglobin can’t carry oxygen effectively. Converts methemoglobin (Fe³⁺) back to normal hemoglobin (Fe²⁺), restoring oxygen delivery. Urinary Tract Antiseptic (rarely used today) Has mild antiseptic properties in the urinary tract when used with other agents. Ifosfamide-Induced Encephalopathy Used off-label to counteract neurotoxicity caused by the chemotherapy drug ifosfamide. Intraoperative Staining Agent Surgeons and urologists may use it to identify structures (e.g., fistulas, ureters, sentinel lymph nodes). Vasoplegic Syndrome in Cardiac Surgery (off-label) Helps raise blood pressure in cases of refractory hypotension after heart surgery, by inhibiting nitric oxide pathways. Diagnostic Aid Sometimes used to help visualize certain body structures or to test for leaks (like gastrointestinal perforations). ⚠️ Important Warnings & Precautions Serotonin Syndrome Risk: Methylene blue is a monoamine oxidase inhibitor (MAOI) — do not use with SSRIs, SNRIs, or other serotonergic drugs. G6PD Deficiency: Can cause hemolysis in people with glucose-6-phosphate dehydrogenase deficiency. Pregnancy: Generally avoided unless absolutely necessary. 💉 Side Effects Pain at the injection site Nausea, vomiting Headache, dizziness Blue or green discoloration of urine, stool, or skin (temporary and harmless) High doses: confusion, agitation, or chest pain

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General Medicine

L-Carnitine Injection is the injectable form of L-carnitine, a naturally occurring amino acid derivative involved in the metabolism of fatty acids. It plays a crucial role in the transport of fatty acids into the mitochondria, where they are burned for energy. L-Carnitine injections are typically used when the body has a deficiency or when enhanced fat metabolism is needed for therapeutic purposes. 🔹 Common Uses of L-Carnitine Injection: 🔋 Fatigue & Energy Production Often used to improve fat metabolism, especially in cases of chronic fatigue or low energy, as it helps the body utilize fat as an energy source more effectively. ⚖️ Weight Loss Support Can be used as an adjunct to weight loss programs to enhance fat burning (though the evidence for significant weight loss with L-carnitine injections alone is limited). 🧠 Cognitive Function & Mental Clarity L-carnitine has shown potential benefits in improving mental clarity and cognitive function, especially in older adults or individuals with Alzheimer's disease or age-related cognitive decline. ❤️ Heart Health May be used in patients with heart disease or heart failure, as it helps improve the efficiency of heart muscle cells by providing them with more energy to function. Supports fat metabolism in heart cells, which is vital for optimal heart function. 🧬 Muscle Recovery & Performance Commonly used by athletes and those undergoing intensive physical training to reduce muscle damage and enhance recovery. It helps in the transport of fatty acids for energy during exercise, reducing reliance on glycogen stores. 🍖 Primary and Secondary Carnitine Deficiency In individuals with genetic disorders or other conditions that impair carnitine production or transport, L-carnitine injections can be used to treat primary carnitine deficiency or to address deficiencies due to renal disease or dialysis. 🍏 Metabolic Disorders (in some cases) Used to support people with metabolic disorders that impair fat oxidation or in cases of dialysis-related carnitine deficiency. 💉 How It’s Administered: Usually given intravenously (IV) or intramuscularly (IM), depending on the clinical scenario. Typically administered in hospital or clinical settings, though outpatient clinics sometimes offer it for weight management or athletic performance. ⚠️ Precautions & Side Effects: Generally safe, but excessive use can lead to: Nausea or abdominal discomfort Muscle weakness or cramping Fishy body odor (a common side effect of high-dose carnitine) Increased risk of seizures (in people with certain conditions like epilepsy) Use with caution in renal patients since carnitine is primarily excreted by the kidneys. Consult a doctor before use in individuals with heart disease, since excess carnitine may have unwanted effects on heart rhythms. ✅ Summary: Condition Use of L-Carnitine Injection Fatigue & Energy Support ✅ Yes Weight Loss (Adjunct Therapy) ✅ Yes (with exercise/diet) Muscle Recovery & Athletic Performance ✅ Yes Heart Health (Heart Failure) ✅ Yes Cognitive Function & Mental Clarity ✅ In age-related decline Carnitine Deficiency ✅ Yes

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General Medicine

Magnesium Chloride Injection is a sterile solution used to treat or prevent magnesium deficiency and related conditions. It's typically given when oral magnesium supplements are ineffective or inappropriate (e.g., in emergencies or hospitalized patients). 🔹 Main Uses of Magnesium Chloride Injection: 🧪 Treatment of Hypomagnesemia (Low Magnesium Levels) Used when blood magnesium levels drop too low, which can cause muscle cramps, fatigue, tremors, and arrhythmias. Common in alcoholics, diabetics, or those with malabsorption syndromes. 🫀 Cardiac Arrhythmias Especially effective in treating: Torsades de pointes (a type of ventricular tachycardia) Irregular heartbeats due to magnesium deficiency. 🤰 Eclampsia and Pre-eclampsia (Pregnancy-related Seizures) Magnesium sulfate is more commonly used, but magnesium chloride may be considered as an alternative. 💨 Severe Asthma Attacks (Adjunct Therapy) Can help relax bronchial smooth muscle and improve breathing during status asthmaticus when other treatments fail. ⚕️ Electrolyte Imbalance Correction Often used with other electrolytes (like potassium) in critical care settings to restore balance in ICU patients. 💉 How It's Given: Intravenously (IV) or Intramuscularly (IM) by a healthcare professional. Dosage depends on the severity of magnesium deficiency or the condition being treated. ⚠️ Precautions & Side Effects: Monitor serum magnesium levels to avoid overdose. High levels can cause: Low blood pressure Flushing Muscle weakness Slow heart rate Respiratory depression or cardiac arrest in severe overdose Use with caution in patients with kidney disease, as magnesium is excreted by the kidneys. ✅ Summary: Condition Use of MgCl Injection Hypomagnesemia ✅ Yes Torsades de Pointes ✅ Yes Pre-eclampsia / Eclampsia ✅ Alternative (to MgSO₄) Severe Asthma (adjunct) ✅ Yes Routine supplementation ⚠️ Only in hospital/clinical setting

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