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'clinical guidelines'

Items tagged with 'clinical guidelines'

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General Medicine

Ondican 2 Injection is a brand of Ondansetron 2 mg/2 mL Injection, manufactured by American Remedies. Ondansetron is a 5-HT₃ receptor antagonist commonly used as an antiemetic to prevent and treat nausea and vomiting associated with various medical conditions. ________________________________________ ✅ Primary Uses Ondican 2 Injection is indicated for: • Chemotherapy-Induced Nausea and Vomiting (CINV): To prevent and treat nausea and vomiting caused by cancer chemotherapy. Radiotherapy-Induced Nausea and Vomiting (RINV): To prevent and treat nausea and vomiting associated with radiation therapy. Postoperative Nausea and Vomiting (PONV): To prevent and treat nausea and vomiting following surgical procedures. These indications are supported by clinical guidelines and pharmacological references. ________________________________________ ⚙️ Mechanism of Action Ondansetron works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting. It specifically inhibits serotonin receptors in the chemoreceptor trigger zone (CTZ) in the brain, thereby preventing the sensation of nausea and the act of vomiting. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Allergy: Do not use if allergic to ondansetron or other 5-HT₃ receptor antagonists. • Cardiac Conditions: Use with caution in patients with a history of heart problems, as ondansetron may affect heart rhythm. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding. Common Side Effects: • Headache • Constipation • DizzinessFatigue Serious Side Effects: • Allergic reactions (rash, itching, swelling) Severe dizziness or fainting • Irregular heartbeat Seek immediate medical attention if any serious side effects occur.

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General Medicine

Nor-ADR Injection is a brand of Noradrenaline (Norepinephrine) Bitartrate Injection, manufactured by American Remedies. It is primarily used in critical care settings to manage severe hypotension (low blood pressure) and shock. ________________________________________ ✅ Primary Uses Nor-ADR Injection is indicated for: • Septic Shock: A life-threatening condition caused by severe infection leading to dangerously low blood pressure. • Cardiogenic Shock: A state where the heart is unable to pump sufficient blood to meet the body's needs. Anaphylactic Shock: A severe allergic reaction causing a sudden drop in blood pressure. • Hypotension During Surgery or Trauma: To maintain adequate blood pressure during and after surgical procedures or traumatic events. • Cardiac Arrest: As an adjunct in the management of cardiac arrest to improve blood flow to vital organs. These indications are supported by clinical guidelines and pharmacological references. ________________________________________ ⚙️ Mechanism of Action Noradrenaline is a potent vasopressor that works by: Alpha-1 Adrenergic Receptor Activation: Causing vasoconstriction, which increases systemic vascular resistance and raises blood pressure. • Beta-1 Adrenergic Receptor Activation: Increasing heart rate and myocardial contractility, thereby enhancing cardiac output. This dual action helps restore blood pressure and improve perfusion to vital organs in shock states. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Administration: Should be administered intravenously under strict medical supervision, typically in an intensive care unit (ICU) setting. • Monitoring: Continuous monitoring of blood pressure and heart rate is essential during administration. • Contraindications: Should not be used in patients with mesenteric or peripheral vascular thrombosis unless absolutely necessary. Common Side Effects: • Hypertension (high blood pressure) • Headache Nausea • Anxiety • Dizziness Serious Side Effects: • Arrhythmias (irregular heartbeats) • Tissue necrosis at the injection site • Reduced renal perfusion leading to renal failure Immediate medical attention is required if any serious side effects occur.

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Cats and Dogs

Electroytes help to carry out hundreds of critical proceses in the body. Loss of water results in electrolye imbalances and needs to be corrected with supplements. One of the most common reasons for water loss is dehydration related to heat stress. Redospet restores electrolyte balance in such hot weather conditions. Many common canine and feline health problems can also result in a loss of not only water but also electrolytes. Redospet helps to maintain hydration by providing electrolytes that help recovery from vomiting, diarrhea, and gastroenteritis. Redospet contains Bacillus coagulans, a probiotic bacteria that supports gut and immune health. Unlike standard Oral rehydration solutions (ORS), Redospet is formulated as per the latest WHO guidelines of the righ osmolarity of 245mOsmol/l and helps to reduce vomiting, stool output/volume and the need fo iv therapy.

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Cats and Dogs

Fiprofort Plus is a combination of the adulticide Fipronil and the insect growth regulator S-methoprene. Fipronil paralyses & kills adult fleas /ticks, while S-methoprene aids to break the life cycle of fleas, thereby helping in controlling the population of fleas in the environment. It offers one-month protection from fleas and ticks. Fiprofort Plus is safe for pets & pet parents. It breaks flea lifecycles & prevents re-infestation. Clinical studies have shown that Fiprofort Plus reduces the egg laying and hatching capacity in female ticks. Monthly use of Fiprofort Plusalong with integrated pest management measures can reduce flea and tick burden.

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Cats and Dogs

Dutrek is the next generation of joint support and mobility. Dutrek helps to strengthen cartilage, improve joint mobility, and reduce joint stiffness to promote flexibility. It contains clinically proven ingredients such as UC-II*, curcumin, rosehip extract and vitamin D3. UC-II is a patented blend of undenatured type II collage that helps to repair and regenerate cartilage. Unlike hydrolzed collagen which is there is many commercially available brands, undenatured type II collagen has not been exposed to heat and enzymes and thereby helps to trigger body’s own response to repair joints and reduce inflammation. The use of UC-II has been well studied in small animals with osteoarthritis.

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Cats and Dogs

Advaren is a urinary stone breaker syrup. It helps to break urinary stones and support kidney health. Advaren contains 3 clinically proven and safe ingredients – Phyllanthus niruri, Tribulus terrestris and Grape seed extract. Phyllanthus niruri prevents stone formation, reduces aggregation of crystals and helps in easy elimination of crystals. Tribulus terrestris acts as a diuretic, which helps to remove excess water from the body and Grape seed is a safe and effective anti-oxidant. Advaren is indicated in dogs and cats with urinary stones and also after surgical removal of stones to prevent recurrence.

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Eye Care

Paripher Eye Drop contains Phenylephrine Hydrochloride 10% and is primarily used in ophthalmology for its mydriatic (pupil-dilating) effects. This formulation is typically employed in clinical settings and is available by prescription.** ________________________________________ 🔍 Uses 1. Pupil Dilation (Mydriasis): Paripher is utilized to dilate the pupil during eye examinations and surgical procedures, allowing for a clearer view of the retina and other internal structures. 2. Treatment of Eye Redness and Irritation: As a decongestant, it constricts blood vessels in the eye, reducing redness and irritation caused by allergies or other factors. 3. Management of Uveitis: Phenylephrine's vasoconstrictive properties aid in managing inflammation associated with uveitis by decreasing blood flow to the affected area. 4. Adjunct in Nasal Decongestion: Though primarily an eye drop, Paripher's active ingredient is also utilized in nasal decongestants to relieve symptoms of the common cold. ________________________________________ ⚠️ Usage Instructions • Application: Instill the prescribed number of drops into the lower conjunctival sac of the eye. • Contact Lenses: Remove soft contact lenses before application and wait at least 10–15 minutes before reinsertion. • Avoid Contamination: Do not touch the dropper tip to any surface, including the eye, to prevent contamination. • Multiple Medications: If using other eye medications, wait at least 10 minutes before applying them to avoid dilution. ________________________________________ ⚠️ Safety and Side Effects • Common Side Effects: Temporary eye discomfort, such as stinging or burning sensations. • Serious Side Effects: Although rare, systemic absorption may lead to increased blood pressure, headache, or dizziness. • Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding.

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General Medicine

Paracan IV is an intravenous (IV) injection that contains paracetamol (also known as acetaminophen). It's commonly used for: 1. Pain Relief: • Post-operative pain: Helps manage pain following surgeries. • Headaches: Effective for treating mild to moderate headaches. • Muscle and joint pain: Used for muscle strains, back pain, or arthritis pain. • Other pain types: Such as toothaches, menstrual cramps, and nerve pain. 2. Fever Reduction: • Paracan IV is used to reduce fever in cases of infections, inflammation, or after surgical procedures. How It Works: Paracan IV works by inhibiting the production of prostaglandins (chemicals in the body that cause pain and inflammation). This provides both pain relief (analgesic effect) and fever reduction (antipyretic effect). Administration: Paracan IV is given through an intravenous (IV) line, typically in a hospital or clinical setting. The dosage depends on the patient's condition, but it's commonly administered when oral medication is not an option. Side Effects: While generally safe when used as directed, it can cause side effects, such as: • Headaches • Nausea or vomiting • Injection site reactions (pain, redness, or swelling) If you experience severe allergic reactions (e.g., difficulty breathing, swelling), immediate medical attention is required. Precautions: Before use, inform your healthcare provider if you have: • Liver or kidney disease • Alcohol use disorder • Allergies to paracetamol or any components of the injection Always use under medical supervision, especially for pregnant or breastfeeding women.

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