Nor-ADR Injection is a brand of Noradrenaline (Norepinephrine) Bitartrate Injection, manufactured by American Remedies. It is primarily used in critical care settings to manage severe hypotension (low blood pressure) and shock. ________________________________________ ✅ Primary Uses Nor-ADR Injection is indicated for: • Septic Shock: A life-threatening condition caused by severe infection leading to dangerously low blood pressure. • Cardiogenic Shock: A state where the heart is unable to pump sufficient blood to meet the body's needs. Anaphylactic Shock: A severe allergic reaction causing a sudden drop in blood pressure. • Hypotension During Surgery or Trauma: To maintain adequate blood pressure during and after surgical procedures or traumatic events. • Cardiac Arrest: As an adjunct in the management of cardiac arrest to improve blood flow to vital organs. These indications are supported by clinical guidelines and pharmacological references. ________________________________________ ⚙️ Mechanism of Action Noradrenaline is a potent vasopressor that works by: Alpha-1 Adrenergic Receptor Activation: Causing vasoconstriction, which increases systemic vascular resistance and raises blood pressure. • Beta-1 Adrenergic Receptor Activation: Increasing heart rate and myocardial contractility, thereby enhancing cardiac output. This dual action helps restore blood pressure and improve perfusion to vital organs in shock states. ________________________________________ ⚠️ Precautions and Side Effects Precautions: • Administration: Should be administered intravenously under strict medical supervision, typically in an intensive care unit (ICU) setting. • Monitoring: Continuous monitoring of blood pressure and heart rate is essential during administration. • Contraindications: Should not be used in patients with mesenteric or peripheral vascular thrombosis unless absolutely necessary. Common Side Effects: • Hypertension (high blood pressure) • Headache Nausea • Anxiety • Dizziness Serious Side Effects: • Arrhythmias (irregular heartbeats) • Tissue necrosis at the injection site • Reduced renal perfusion leading to renal failure Immediate medical attention is required if any serious side effects occur.

Milicor 10mg Injection Marketer Samarth Life Sciences Pvt Ltd SALT COMPOSITION Milrinone (10mg) Storage Store below 30°C Uses of Milicor Injection Heart Failure Product introduction Milicor 10mg Injection is a medicine used for short-term treatment of heart failure. It is also used to treat patients with a poorly functioning heart after heart surgery. It makes the heart pump blood more efficiently. It is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. The doctor may closely monitor your blood pressure, heart rate, and ECG until you become stable. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection. Common side effects of this medicine include hypotension, headaches, arrhythmias, and tachycardia. Consult your doctor if these effects bother you. This medicine is used with caution for some people. Thus, you must inform the doctor if you are suffering from any kidney disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly. Side effects of Milicor Injection Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Milicor Hypotension (low blood pressure) Headache Arrhythmia (irregular heartbeats) Tachycardia How to use Milicor Injection Your doctor or nurse will give you this medicine. Kindly do not self administer. How Milicor Injection works Milicor 10mg Injection is a vasodilator. It increases the level of a chemical messenger (cAMP), which helps the smooth muscles to relax. Thus, dilates the blood vessels for better blood flow into the heart. It also has blood thinning property. Safety advice warnings Alcohol CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Milicor 10mg Injection. Please consult your doctor. warnings Pregnancy CONSULT YOUR DOCTOR Milicor 10mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. warnings Breast feeding SAFE IF PRESCRIBED Milicor 10mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. warnings Driving CONSULT YOUR DOCTOR It is not known whether Milicor 10mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. warnings Kidney CAUTION Milicor 10mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Milicor 10mg Injection may be needed. Please consult your doctor. warnings Liver SAFE IF PRESCRIBED Milicor 10mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Milicor 10mg Injection may not be needed in these patients. Please consult your doctor.

INTRODUCTION ABOUT TAXONAB 100MG INJECTION TAXONAB 100MG INJECTION contains Paclitaxel which belongs to a group of anti-cancer medicines called Taxanes. TAXONAB 100MG INJECTION is used to manage ovarian and breast cancer as a first line of therapy and as a second line of management when platinum containing medicines (such as cisplatin) or anthracyclines are insufficient to manage the disease in affected individuals. TAXONAB 100MG INJECTION is also used to manage advanced NSCLC (non-small cell lung cancer) when surgery/radiation therapy is not suitable. The medicine is also indicated for use to manage AIDS-related Kaposi’s sarcoma when other managements (such as anthracyclines) are insufficient to manage the disease in affected individuals. TAXONAB 100MG INJECTION is not recommended for use in patients allergic to paclitaxel and polyoxyethylated castor oil. It is also not recommended for use in patients with few white blood cells count and serious & uncontrolled infection. The medicine is also not used in patients suffering from severe liver disease. Before receiving TAXONAB 100MG INJECTION, inform your doctor if you had previously received radiation to your chest and/or suffering from thrombocytopenia (low platelet count)/acute infections (such as herpes zoster, chickenpox, herpes), kidney problems (such as chronic kidney disease), liver problems (such as mild/moderate hepatic impairment) and/or heart problems (such as severe coronary artery disease, myocardial infarction and arrhythmias). TAXONAB 100MG INJECTION is not recommended for use during pregnancy. Women of child-bearing potential should use effective contraception method while receiving TAXONAB 100MG INJECTION which should be continued for next-6 months after completing the management. The medicine is also not recommended for use in breastfeeding women. TAXONAB 100MG INJECTION is also not recommended for use in children and adolescents (aged below 18 years). The medicine can be used with caution in elderly patients (aged above 65 years) after consulting the doctor. The most common side effects of receiving TAXONAB 100MG INJECTION are minor allergic reactions (such as flushing, rash, itching), shortness of breath, sore throat/mouth ulcers, diarrhea, nausea, vomiting and/or loss of hair. Consult your doctor if any of these symptoms worsen. USES OF TAXONAB 100MG INJECTION Manage ovarian and breast cancer. Manage advanced NSCLC (non-small cell lung cancer) Manage AIDS-related Kaposi’s sarcoma in affected individuals. HOW TAXONAB 100MG INJECTION WORKS TAXONAB 100MG INJECTION works by interfering with the microtubule structures in the cell (substance which aids cancer cells to divide and multiply) thus inhibiting the growth of cancer cells and managing its spread in affected individuals. DIRECTIONS FOR USE TAXONAB 100MG INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. SIDE EFFECTS OF TAXONAB 100MG INJECTION COMMON minor allergic reactions such as flushing, rash and/or itching infections such as upper respiratory infection, urinary tract infection shortness of breath sore throat/mouth ulcers, sore and red mouth diarrhea, nausea, vomiting loss of hair pain in the muscles, cramps, joints fever, severe chills, headache, dizziness, tiredness, looking pale bleeding, bruising more easily than normal signs of peripheral neuropathy such as numbness, tingling/weakness in arms and legs temporary mild nail change and skin changes reactions at injection sites such as localized swelling, pain and/or redness of the skin. UNCOMMON septic shock (severe drop in blood pressure) due to infections racing heartbeat, rapid beating of the heart, respiratory distress, heart attack, heart block fatigue, sweating, fainting, significant allergic reactions, phlebitis (inflammation of a vein), swelling of the face, lips, mouth, tongue and/or throat back pain, chest pain, pain around hands and feet, chills, abdominal pain. RARE febrile neutropenia (type of fever) due to low white blood cell count associated with fever and increased risk of infection motor neuropathy (disease that affects your body’s motor nerves) pulmonary embolism (blockade of lung artery), lung fibrosis (damaged/scarred lung tissue), interstitial pneumonia (scarring of lung tissue), pleural effusion (build of fluid between lungs and chest) bowel obstruction, bowel perforation, inflammation of colon, inflammation of the pancreas (pancreatitis) skin redness peritonitis (inflammation of abdominal layer) fever, dehydration, weakness anaphylactic reactions (life threatening allergic reaction). HOW TO MANAGE SIDE EFFECTS Diarrhea: Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to manage diarrhea. Consult your doctor and inform them if the symptom gets worse.

Dobutacan 12 Injection is a brand of Dobutamine Hydrochloride 12.5 mg/mL, a synthetic catecholamine used in critical care settings to support heart function. It is administered intravenously under medical supervision. ________________________________________ 🩺 Medical Uses Dobutacan 12 Injection is indicated for: • Cardiac Decompensation: Acute heart failure due to conditions like myocardial infarction, cardiomyopathies, or post-cardiac surgery. • Cardiogenic Shock: A state of low cardiac output leading to inadequate tissue perfusion. • Septic Shock: A severe infection causing low blood pressure and organ dysfunction. • Stress Echocardiography: As a pharmacological agent to assess coronary artery disease when exercise is not feasible. It works by stimulating beta-1 adrenergic receptors, increasing heart contractility and stroke volume, thereby improving cardiac output. ________________________________________ ⚙️ Dosage and Administration Dobutacan 12 Injection is administered intravenously in a hospital setting. The typical dosage ranges from 2.5 to 10 mcg/kg/min, adjusted based on the patient's response. In some cases, doses up to 20 mcg/kg/min may be required. ________________________________________ ⚠️ Precautions and Contraindications Before using Dobutacan 12 Injection, inform your healthcare provider if you have: • Allergies to dobutamine or other components of the injection. • A history of arrhythmias or heart disease. • Kidney or liver problems. • A history of stroke or blood clots. This medication is typically administered by healthcare professionals in a clinical setting and is not intended for self-administration. It is usually given as an intramuscular (IM) or intravenous (IV) injection. ________________________________________ 💊 Side Effects Common side effects may include: • Headache • Nausea or vomiting • Dizziness or lightheadedness • Injection site reactions (pain, redness, or swelling) Serious side effects are rare but can occur. Seek immediate medical attention if you experience symptoms like chest pain, shortness of breath, or signs of gastrointestinal bleeding.

Cezocalm Injection is a brand name for Chlorpromazine Hydrochloride Injection, manufactured by American Remedies. Chlorpromazine is a first-generation antipsychotic medication belonging to the phenothiazine class. ________________________________________ 🩺 Uses of Cezocalm Injection Cezocalm Injection is primarily used to manage various psychiatric and neurological conditions, including: • Schizophrenia: A chronic mental health disorder characterized by distorted thinking, perception, emotions, and behavior. • Acute Psychotic Episodes: Short-term episodes of severe mental disturbances. • Manic Episodes in Bipolar Disorder: Periods of abnormally elevated mood and energy levels. • Severe Behavioral Problems in Children: Such as hyperactivity and aggression. • Severe Nausea and Vomiting: Especially when other treatments are ineffective. Hiccups: Persistent and intractable cases. • Preoperative Sedation: To relax patients before surgery. ________________________________________ 💊 Mechanism of Action Chlorpromazine works by: Blocking dopamine receptors in the brain, which helps in reducing symptoms of psychosis. • Exhibiting sedative properties by affecting various neurotransmitter systems. ________________________________________ ⚠️ Precautions and Side Effects Before administering Cezocalm Injection, inform your healthcare provider if you have: • Allergies to chlorpromazine or other medications. • A history of liver or kidney disease. • Heart conditions, especially arrhythmias. • Blood disorders. • Seizure disorders. • Pregnancy or breastfeeding status. Common side effects may include: Drowsiness or sedation. • Dizziness. • Dry mouth. • Constipation. • Hypotension (low blood pressure). • Extrapyramidal symptoms (e.g., tremors, rigidity). • Photosensitivity.

Amioron Injection is a prescription medication primarily used to manage serious cardiac arrhythmias, particularly life-threatening ventricular arrhythmias. ________________________________________ 🩺 Primary Uses • Ventricular Fibrillation (VF): A life-threatening irregular heart rhythm originating in the ventricles. • Ventricular Tachycardia (VT): A rapid heart rate originating from the ventricles, which may be unstable and require immediate treatment. Amioron is classified as a Class III antiarrhythmic agent and works by inhibiting certain electrical impulses in the heart, thereby stabilizing the heart rhythm. ________________________________________ ⚠️ Side Effects Common side effects may include: • Injection site reactions (pain, redness, swelling) • Dizziness or lightheadedness • Fatigue • Nausea Serious side effects can occur, including prolonged QT interval, hypotension, or worsening arrhythmias. Regular monitoring by healthcare professionals is essential during treatment. ________________________________________ 💊 Administration Amioron Injection is administered intravenously under strict medical supervision, typically in a hospital or emergency care setting. The dosage and duration depend on the specific cardiac condition and patient response. ________________________________________ ⚠️ Precautions • Inform your doctor if you have a history of thyroid disorders, liver disease, or respiratory issues. • Regular ECG monitoring is recommended during treatment. Use during pregnancy or breastfeeding should be discussed with a healthcare provider

Magnesium Chloride Injection is a sterile solution used to treat or prevent magnesium deficiency and related conditions. It's typically given when oral magnesium supplements are ineffective or inappropriate (e.g., in emergencies or hospitalized patients). 🔹 Main Uses of Magnesium Chloride Injection: 🧪 Treatment of Hypomagnesemia (Low Magnesium Levels) Used when blood magnesium levels drop too low, which can cause muscle cramps, fatigue, tremors, and arrhythmias. Common in alcoholics, diabetics, or those with malabsorption syndromes. 🫀 Cardiac Arrhythmias Especially effective in treating: Torsades de pointes (a type of ventricular tachycardia) Irregular heartbeats due to magnesium deficiency. 🤰 Eclampsia and Pre-eclampsia (Pregnancy-related Seizures) Magnesium sulfate is more commonly used, but magnesium chloride may be considered as an alternative. 💨 Severe Asthma Attacks (Adjunct Therapy) Can help relax bronchial smooth muscle and improve breathing during status asthmaticus when other treatments fail. ⚕️ Electrolyte Imbalance Correction Often used with other electrolytes (like potassium) in critical care settings to restore balance in ICU patients. 💉 How It's Given: Intravenously (IV) or Intramuscularly (IM) by a healthcare professional. Dosage depends on the severity of magnesium deficiency or the condition being treated. ⚠️ Precautions & Side Effects: Monitor serum magnesium levels to avoid overdose. High levels can cause: Low blood pressure Flushing Muscle weakness Slow heart rate Respiratory depression or cardiac arrest in severe overdose Use with caution in patients with kidney disease, as magnesium is excreted by the kidneys. ✅ Summary: Condition Use of MgCl Injection Hypomagnesemia ✅ Yes Torsades de Pointes ✅ Yes Pre-eclampsia / Eclampsia ✅ Alternative (to MgSO₄) Severe Asthma (adjunct) ✅ Yes Routine supplementation ⚠️ Only in hospital/clinical setting

LIVOMAG Injection (Magnesium Chloride Injection) is used to treat or prevent magnesium deficiency and manage various medical conditions that require magnesium supplementation. 🔹 Common Uses of LIVOMAG Injection: Magnesium Deficiency (Hypomagnesemia) Used when blood magnesium levels are low, especially in hospitalized or critically ill patients. Eclampsia & Pre-eclampsia (in pregnancy) Acts as a central nervous system depressant to prevent or treat seizures in pregnant women with eclampsia. Cardiac Arrhythmias Especially helpful in treating torsades de pointes, a specific type of irregular heartbeat. Severe Asthma (Adjunct therapy) IV magnesium can help relax bronchial muscles during acute asthma attacks when other treatments fail. Neuromuscular Function Support Used in cases of muscle cramps, spasms, or twitching due to low magnesium. Electrolyte Imbalance Correction Often part of treatment in critical care, especially in ICU settings when patients have multiple electrolyte imbalances. 💉 Dosage & Administration: Administered intravenously (IV) or intramuscularly (IM) depending on the clinical situation. Doses vary based on severity and condition being treated. ⚠️ Precautions & Side Effects: Too much magnesium can lead to low blood pressure, respiratory depression, or irregular heartbeat. Caution in patients with kidney disease, as magnesium is excreted by the kidneys. Monitor serum magnesium levels during treatment.

Chronic kidney disease is a common kidney disorder in adult and aged dogs and cats. The gradual decline in kidney function leads to an accumulation of toxins normally cleared by the kidneys, resulting in uremia. Renodis is a combination of prebiotic and probiotic bacteria that helps to normalize gut dysbiosis, a condition that happens when there is an imbalance between good and bad bacteria in the gut. Renodis contains 3 live therapeutic bacteria that have been validated in patients with kidney disease. Renodis performs natural enteric dialysis by helping to restore the balance of bacteria in the gut. It can further help to slow down uremic toxin build-up in patients with renal insufficiency